Details of the Drug

General Information of Drug (ID: DMDFA3E)

Drug Name
349U85.HCL
Synonyms 6-Piperidinoquinolin-2(1H)-one hydrochloride
Indication
Disease Entry ICD 11 Status REF
Cardiovascular disease BA00-BE2Z Phase 1 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski):
0		 Molecular Weight 264.75
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 1
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 2
Chemical Identifiers
Formula
C14H17ClN2O
IUPAC Name
6-piperidin-1-yl-1H-quinolin-2-one;hydrochloride
Canonical SMILES
C1CCN(CC1)C2=CC3=C(C=C2)NC(=O)C=C3.Cl
InChI
InChI=1S/C14H16N2O.ClH/c17-14-7-4-11-10-12(5-6-13(11)15-14)16-8-2-1-3-9-16;/h4-7,10H,1-3,8-9H2,(H,15,17);1H
InChIKey
KYTREJMWHJPVSI-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
164016
CAS Number
116942-30-4
TTD ID
D0F7NT

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Phosphodiesterase 3 (PDE3) TTZCG4L NOUNIPROTAC Modulator [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Pharmacokinetics and pharmacodynamics of a new cardiotonic vasodilator agent, 349U85, in normal subjects. Clin Pharmacol Ther. 1994 Jan;55(1):55-63.