Details of Disease

General Information of Disease (ID: DIS2IQDX)

Disease Name Cardiovascular disease
Synonyms
circulatory system disease; cardiovascular disease; cardiovascular disorder; disorder of cardiovascular system; cardiovascular disease (CVD); cardiovascular system disease; disease of subdivision of hemolymphoid system; disease or disorder of cardiovascular system; disease of cardiovascular system; cardiovascular system disease or disorder
Disease Class BA00-BE2Z: Cardiovascular disease
Definition A disease involving the cardiovascular system.
Disease Hierarchy
DISH7H5I: Human disease
DIS2IQDX: Cardiovascular disease
ICD Code
ICD-11
ICD-11: BA00-BE2Z
Disease Identifiers
MONDO ID
MONDO_0004995
MESH ID
D002318
UMLS CUI
C0007222
MedGen ID
2848
SNOMED CT ID
49601007

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 39 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Acarbose DMRM3AW Approved Small molecular drug [1]
Adoniside DMJDZ83 Approved NA [2]
Alacepril DML6SRO Approved Small molecular drug [2]
Alpha-acetyldigoxin DMAS02L Approved Small molecular drug [2]
Aspirin DM672AH Approved Small molecular drug [3]
Atorvastatin DMF28YC Approved Small molecular drug [2]
Bempedoic acid DM1CI9R Approved Small molecular drug [4]
Beta-acetyldigoxin DMI6GKT Approved Small molecular drug [2]
Convallatoxin DM91GKZ Approved Small molecular drug [2]
Delapril DM7EUK3 Approved Small molecular drug [5]
Digitalin DM01P50 Approved Small molecular drug [2]
Exenatide DMYHBKN Approved Small molecular drug [6]
FENOFIBRIC ACID DMGO2MC Approved Small molecular drug [7]
Gitalin DM0GIPM Approved NA [2]
Hidrosmin DM05HP4 Approved Small molecular drug [2]
Imidapril DMUL7T1 Approved Small molecular drug [2]
Iodixanol DMA2Q8L Approved NA [2]
Iopamidol DM4I07A Approved Small molecular drug [2]
Ioversol DMJKHDL Approved Small molecular drug [2]
Ioxaglate DM7245Q Approved Small molecular drug [2]
Ioxithalamate DMZGNXN Approved NA [2]
Kawain DMENHCI Approved Small molecular drug [2]
Lanatoside a DMOC7MO Approved Small molecular drug [2]
Lanatoside b DMQOLRL Approved Small molecular drug [2]
Lanatoside c DMNB3RP Approved Small molecular drug [2]
Levovist DMZYSUG Approved NA [2]
Lovastatin DM9OZWQ Approved Small molecular drug [8]
Macitentan DMP79A1 Approved Small molecular drug [9]
Pemafibrate DMD1VZL Approved NA [4]
Perflexane-lipid microsphere DMY9UR6 Approved NA [2]
Prasterone DM67VKL Approved Small molecular drug [10]
Sennoside a DM4A4ZM Approved Small molecular drug [2]
Sennoside b DMQSU98 Approved Small molecular drug [2]
Sotagliflozin DMMLXA9 Approved Small molecular drug [4]
Sulfur hexafluoride lipid-type a microspheres DM1SV6T Approved NA [11]
Sulphur hexafluoride microbubble ultrasound agent DMJ9EDH Approved NA [12]
Temocapril hydrochloride DM0JXFL Approved Small molecular drug [2]
Vitamin E DMZC90K Approved Small molecular drug [2]
Mirogabalin DM5GIWZ Registered Small molecular drug [13]
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⏷ Show the Full List of 39 Drug(s)
This Disease is Treated as An Indication in 65 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
BiovaxlD DMRHD2G Preregistration NA [14]
Apabetalone DMCGATN Phase 3 NA [15]
Evacetrapib DMCDZ15 Phase 3 Small molecular drug [16]
NT0102 DM797Z8 Phase 3 NA [17]
PB-127 DMR7T3X Phase 3 Small molecular drug [18]
Pelacarsen DMY757D Phase 3 Antisense oligonucleotide [19]
TQJ230 DM9LI62 Phase 3 NA [20]
1-MNA DM5DC3R Phase 2/3 NA [4]
LCP-AtorFen DM9M7GE Phase 2/3 NA [21]
Myo-inositol hexaphosphate DME2CAK Phase 2/3 Small molecular drug [22]
PEG-bHb-CO DMJ38X9 Phase 2/3 NA [23]
3,5-diiodothyropropionic acid DML8M5T Phase 2 Small molecular drug [24]
A-101 DMNDZMB Phase 2 Small molecular drug [25]
AKCEA-ANGPTL3-LRX DMR8W7Y Phase 2 NA [4]
ARI-3037MO DM9LNXS Phase 2 NA [4]
AX-200 DMTAEMB Phase 2 NA [26]
AZD8233 DMBT2D2 Phase 2 Antisense oligonucleotide [27]
AZD8601 DMSQSR6 Phase 2 NA [4]
BAY-Y-5959 DMLO18H Phase 2 NA [28]
BXT-51072 DMD8GNB Phase 2 Small molecular drug [29]
CALDARET HYDRATE DMDV8MK Phase 2 Small molecular drug [30]
CER-001 DMWUQI9 Phase 2 NA [4]
CSL-112 DMZCG91 Phase 2 NA [4]
Delphinidin DMS2WIN Phase 2 Small molecular drug [31]
Etripamil DMXZKV7 Phase 2 NA [32]
INS-50589 DMKZUVC Phase 2 Small molecular drug [33]
LA-419 DM87B0C Phase 2 Small molecular drug [34]
LY-2189102 DMU81BH Phase 2 Antibody [35]
LY3015014 DMFMKQ3 Phase 2 Antibody [36]
LY3473329 DM9AP55 Phase 2 Small molecule [37]
MEDI6570 DML8S0W Phase 2 Antibody [38]
MPSK3169A DMMRYEK Phase 2 NA [39]
NCX-1000 DM2YIZH Phase 2 Small molecular drug [40]
Odiparcil DMWCBY7 Phase 2 Small molecular drug [41]
SLV-337 DMRY6NX Phase 2 NA [42]
TA-8995 DMAZHT0 Phase 2 NA [4]
ZK-91587 DMJ94L0 Phase 2 Small molecular drug [43]
Autologous VEGF-and angiopoietin-1-expressing endothelial and smooth muscle cell therapy DMPNUYZ Phase 1/2 NA [44]
EchoGen DM3GQXA Phase 1/2 NA [45]
OXY-111A DMTH75R Phase 1/2 NA [46]
349U85.HCL DMDFA3E Phase 1 Small molecular drug [47]
ACT-178882 DMOZ3AT Phase 1 NA [48]
Adipose-derived stem cell therapy DMW2W1R Phase 1 NA [49]
AMG 529 DMNEFQ6 Phase 1 NA [4]
AZD3366 DMS57UF Phase 1 Small molecule [50]
AZD5462 DM2QQZO Phase 1 Small molecule [51]
CARD-024 DM4SNK8 Phase 1 NA [52]
COR-001 DMEVHKO Phase 1 NA [4]
DB-772d DM48891 Phase 1 NA [53]
FP-045 DMV9FTH Phase 1 NA [4]
IL-1 Monoclonal Antibody DM1F7EX Phase 1 NA [54]
ISIS-CRP DMQDUG4 Phase 1 Antisense drug [55]
K-312 DME8K4S Phase 1 NA [4]
Monohydroxyethylrutoside DMAQJHO Phase 1 NA [56]
NCX-6560 DMM7RC5 Phase 1 NA [57]
NV-04 DMNF09S Phase 1 NA [58]
PCSK9 Adnectin DMH86KO Phase 1 NA [59]
PF-06427878 DMGB32Z Phase 1 NA [4]
REGN-728 DMWUDE1 Phase 1 NA [60]
Rilapladib DMB9861 Phase 1 Small molecular drug [61]
SAR247799 DMUAJZD Phase 1 NA [4]
SLV-338 DM7WKTM Phase 1 NA [62]
Temanogrel DM7Q4EX Phase 1 Small molecular drug [63]
XL652/XL014 DM89NML Phase 1 NA [64]
PMID23981898C11d DMX1IZ9 Clinical trial Small molecular drug [65]
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⏷ Show the Full List of 65 Drug(s)
This Disease is Treated as An Indication in 41 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Etilefrine DM67PWD Withdrawn from market Small molecular drug [2]
ViaScint DM3QYWK Discontinued in Preregistration NA [66]
Eprotirome DMYFQTD Discontinued in Phase 3 Small molecular drug [67]
LOTRAFIBAN DMHE804 Discontinued in Phase 3 Small molecular drug [68]
ORBOFIBAN DMEDLXJ Discontinued in Phase 3 Small molecular drug [15]
Pexelizumab DM4IM0G Discontinued in Phase 3 Antibody [69]
SIBRAFIBAN DMZU1TV Discontinued in Phase 3 Small molecular drug [15]
Tagatose DMK7DA8 Discontinued in Phase 3 Small molecular drug [70]
XEMILOFIBAN DMBRYT8 Discontinued in Phase 3 Small molecular drug [15]
AM103 DMAQNBW Discontinued in Phase 2 Small molecular drug [71]
E-4021 DMWIA56 Discontinued in Phase 2 Small molecular drug [72]
EP-2104R DMG3R14 Discontinued in Phase 2 NA [73]
H-409/22 DMYJ9CF Discontinued in Phase 2 Small molecular drug [74]
KC706 DMBX6C7 Discontinued in Phase 2 NA [75]
NC-100150 DMVP015 Discontinued in Phase 2 NA [76]
OPC-8490 DM9ORUL Discontinued in Phase 2 Small molecular drug [77]
SL65.0472 DMU5RKC Discontinued in Phase 2 Small molecular drug [78]
BMS-844421 DMMIUR3 Discontinued in Phase 1 NA [79]
EMD-53998 DMVS8IE Discontinued in Phase 1 Small molecular drug [80]
GED-aPC DM041IZ Discontinued in Phase 1 NA [81]
R 80122 DMU93JL Discontinued in Phase 1 Small molecular drug [82]
RG-7236 DMDPWCM Discontinued in Phase 1 NA [83]
AQ-RA-741 DMPMW03 Terminated Small molecular drug [84]
AWD-160-275 DMFOPSX Terminated NA [85]
BMS-182657 DM0K4DZ Terminated NA [86]
BVF-247 DM0JHLA Terminated NA [87]
CS-207 DMFJ4VT Terminated NA [88]
CY-1747 DMANUPL Terminated NA [89]
DPI-201-106 DM1AQVE Terminated Small molecular drug [90]
DV-7028 DMKNJM7 Terminated Small molecular drug [91]
Flosequinan DMY89KQ Terminated Small molecular drug [92]
ICI-D-1542 DM2GNF3 Terminated NA [93]
ISIS 353512 DMHS32W Terminated NA [94]
LSI-518P DMFJPYV Terminated NA [95]
Myomap DMEK00Y Terminated NA [96]
PX-867 DMCNE2G Terminated Small molecular drug [97]
SC-108 DM96CTH Terminated NA [98]
TBC-395 DMQVC0I Terminated NA [99]
UK-51656 DM23YPS Terminated NA [100]
Vapiprost DMJLV03 Terminated Small molecular drug [101]
WS-75624B DM89BA1 Terminated Small molecular drug [102]
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⏷ Show the Full List of 41 Drug(s)
This Disease is Treated as An Indication in 49 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
A-003 DMD47Z9 Investigative NA [103]
ACS-14 DMGCI8O Investigative NA [103]
ALD-306 DM0A0IW Investigative NA [103]
Aom-0821 DMTXDQ9 Investigative NA [103]
AR-9273 DMP07GX Investigative NA [103]
BA-207 DM8XT75 Investigative NA [103]
BIA-12 DM4LL4H Investigative NA [103]
BPL-001 DMKX6LY Investigative NA [104]
C4X-301 DMGHY1P Investigative NA [103]
CAT-3000 DMAI14Y Investigative NA [103]
CGEN-856 DMAT8J6 Investigative NA [105]
CPG23CARD DMJCDUW Investigative NA [103]
CT-406 DMJAY6D Investigative NA [103]
ECFCs DMMFVPE Investigative NA [103]
FP-0210 DM98MMA Investigative NA [103]
FP-0220 DMEWAXQ Investigative NA [103]
FP-0230 DM80Z4B Investigative NA [103]
Gadomelitol DM4CN38 Investigative NA [103]
GKT-136901 DMJN1SA Investigative NA [103]
GSK-1842799C DM2KT17 Investigative NA [106]
HDL-based therapeutics DM2AV22 Investigative NA [103]
HG-1154 DM8W4IL Investigative NA [103]
IG-MD-009 DM9X3RQ Investigative NA [103]
IPS cell program DM1Y7UE Investigative NA [103]
JIN-2013 DM7FQHO Investigative NA [103]
KM-01221 DMG594K Investigative Small molecular drug [107]
KT-1 DM2UY1Z Investigative Small molecular drug [103]
LPCVD DMRCYU7 Investigative NA [103]
Modified SDF-1 DM6O0VK Investigative NA [103]
NFTA-105 DM2BGNN Investigative NA [103]
NFTB-104 DMV7HK0 Investigative NA [103]
NFTC-103 DM58AZO Investigative NA [103]
NVLS/FX-18A DM0TPZ8 Investigative Small molecular drug [103]
PA-10040 DMELTM2 Investigative NA [108]
PA-508 DM8Z82S Investigative NA [103]
PA08140 DMMCDSD Investigative NA [103]
PRT-060096 DM25EDB Investigative NA [109]
PRT-061103 DMFCNTR Investigative NA [103]
RESP-3000 DMN5GE5 Investigative NA [103]
RLY-106 DMP78J4 Investigative NA [103]
RVX-408 DMXLUQB Investigative NA [103]
Safflower seed-derived apolipoprotein A1 DMFBL8E Investigative NA [103]
ShRNA apolipoprotein B100 gene siliencer DMOAPVF Investigative NA [103]
ST-0701 DM8E8AA Investigative NA [103]
ST-0703 DMM5X5W Investigative NA [103]
Tiapamil DMWSI0H Investigative Small molecular drug [103]
TK-115339 DMBAMGP Investigative NA [103]
VAS-2870 DMG2DAY Investigative NA [103]
XEL-007DO DM49CI4 Investigative NA [103]
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⏷ Show the Full List of 49 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 438 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ABCG1 TTMWDGU Limited Biomarker [111]
ADRA2B TTWM4TY Limited Biomarker [112]
ADRB1 TTR6W5O Limited Altered Expression [113]
AMD1 TTBFROQ Limited Genetic Variation [114]
ANGPT1 TTWNQ1T Limited Biomarker [115]
ARSA TTYQANR Limited Biomarker [116]
CALCR TTLWS2O Limited Biomarker [117]
CCR5 TTJIH8Q Limited Genetic Variation [118]
CFH TTUW6OP Limited Biomarker [119]
CTSS TTUMQVO Limited Biomarker [120]
CXCR6 TT2BVUA Limited Biomarker [112]
CYP19A1 TTSZLWK Limited Genetic Variation [121]
ELANE TTPLTSQ Limited Biomarker [122]
ENG TTB30LE Limited Altered Expression [123]
FABP3 TT3TGLR Limited Biomarker [124]
G6PD TTKN8W0 Limited Biomarker [125]
GIP TT40HS5 Limited Biomarker [126]
GRK2 TTAZ3MN Limited Biomarker [127]
HTRA1 TT8POQR Limited Genetic Variation [114]
IL23A TTC1GLB Limited Biomarker [128]
KDM3A TTKXS4A Limited Biomarker [129]
KLK3 TTS78AZ Limited Biomarker [130]
LEPR TT0HD6V Limited Genetic Variation [131]
LIPG TTHSZXO Limited Biomarker [132]
MAP4K4 TT6NI13 Limited Biomarker [133]
MGAM TTXWASR Limited Genetic Variation [134]
MME TT5TKPM Limited Biomarker [135]
MMP1 TTMX39J Limited Biomarker [136]
MMP12 TTXZ0KQ Limited Biomarker [137]
MMP8 TTGA1IV Limited Biomarker [138]
MTTP TTUS1RD Limited Biomarker [139]
NPPC TTRK0B9 Limited Biomarker [140]
PDE5A TTJ0IQB Limited Biomarker [141]
PDGFC TTOABM9 Limited Genetic Variation [142]
PLA2G1B TT9V5JH Limited Biomarker [143]
PPIA TTL2ADK Limited Genetic Variation [144]
PTPN1 TTELIN2 Limited Biomarker [145]
S100A8 TT4AF6N Limited Biomarker [146]
SCARB1 TTRE324 Limited Genetic Variation [147]
SCN5A TTZOVE0 Limited Biomarker [148]
SCN8A TT54ERL Limited Biomarker [149]
SLC2A4 TTP6MT5 Limited Biomarker [150]
SLC33A1 TTL69WB Limited Genetic Variation [151]
SLC6A2 TTAWNKZ Limited Genetic Variation [152]
SLC6A4 TT3ROYC Limited Genetic Variation [153]
TFPI TT068JH Limited Biomarker [154]
THBD TTAPV67 Limited Biomarker [155]
THBS1 TTKI0H1 Limited Biomarker [156]
TNFSF11 TT9E8HR Limited Biomarker [157]
TSPO TTPTXIN Limited Biomarker [158]
TXN TTZJ5U9 Limited Biomarker [159]
UCP2 TTSC2YM Limited Biomarker [160]
VKORC1 TTEUC8H Limited Genetic Variation [161]
ABCG5 TTKZ7WY moderate Biomarker [162]
ACKR1 TTKY2NS moderate Biomarker [163]
ADAM8 TTQWYMD moderate Biomarker [164]
ADAMTS5 TTXSU2Y moderate Biomarker [165]
ADM2 TTM642F moderate Biomarker [166]
ADRA1A TTNGILX moderate Biomarker [112]
AGRP TT4DE1O moderate Biomarker [167]
AKR1B1 TTFBNVI moderate Biomarker [168]
ALPL TTMR5UV moderate Altered Expression [169]
APOA4 TTNC3WS moderate Biomarker [170]
B2M TTY7FKA moderate Biomarker [171]
BRD7 TT07ZS1 moderate Genetic Variation [172]
BRS3 TTKYEPM moderate Biomarker [112]
BTLA TTER58P moderate Altered Expression [173]
CA2 TTANPDJ moderate Biomarker [174]
CAPN1 TT1WBIJ moderate Altered Expression [175]
CASP1 TTCQIBE moderate Biomarker [176]
CCR2 TTFZYTO moderate Biomarker [177]
CPB2 TTP18AY moderate Genetic Variation [178]
CTH TTLQUZS moderate Biomarker [179]
CTSK TTDZN01 moderate Genetic Variation [180]
CYBB TT5T8MR moderate Biomarker [181]
CYP2J2 TTNE1C7 moderate Altered Expression [182]
DUSP1 TTG8HIM moderate Altered Expression [183]
ENAH TTY36UA moderate Genetic Variation [154]
F11 TTDM4ZU moderate Genetic Variation [184]
F2RL3 TTD0652 moderate Biomarker [185]
F7 TTF0EGX moderate Genetic Variation [186]
FABP2 TTS4YLO moderate Genetic Variation [187]
FADS2 TTT2VDU moderate Genetic Variation [188]
FCGR3A TTIFOC0 moderate Biomarker [189]
FGG TTR31L7 moderate Biomarker [190]
GALR1 TTX3HNZ moderate Biomarker [191]
GLUL TTURQ2G moderate Biomarker [192]
GP6 TTTJUVZ moderate Biomarker [193]
GPER1 TTDSB34 moderate Biomarker [194]
HCAR2 TTWNV8U moderate Biomarker [195]
HCRTR2 TT9N02I moderate Biomarker [196]
HSPB3 TTLH8WG moderate Altered Expression [197]
HSPD1 TT9HL5R moderate Biomarker [198]
HTR2A TTJQOD7 moderate Genetic Variation [153]
IGFBP1 TTCJTWF moderate Biomarker [199]
IL1RL1 TT4GZA4 moderate Genetic Variation [200]
IL32 TTD4G7L moderate Genetic Variation [201]
IRS1 TTAJSQ0 moderate Biomarker [202]
ITGB3 TTJA1ZO moderate Biomarker [203]
KCNH2 TTQ6VDM moderate Genetic Variation [148]
KEAP1 TT3Z6Y9 moderate Biomarker [204]
LBP TTVQJLY moderate Biomarker [205]
LCAT TTGZ91P moderate Altered Expression [206]
LPAR2 TTB7Y8I moderate Biomarker [112]
LTA TTP73TM moderate Genetic Variation [207]
MAS1 TTOISYB moderate Biomarker [115]
MBP TT2RY5P moderate Biomarker [208]
MGLL TTZ963I moderate Biomarker [209]
MMP7 TTMTWOS moderate Altered Expression [210]
MSR1 TT2TDH9 moderate Biomarker [211]
MTR TTUTO39 moderate Biomarker [212]
MUSK TT6SA0X moderate Biomarker [213]
NAMPT TTD1WIG moderate Genetic Variation [214]
NOD1 TTYSRXM moderate Biomarker [215]
NPEPPS TT371QC moderate Biomarker [130]
NPR3 TTWVLS6 moderate Biomarker [216]
NTN1 TT0AH4L moderate Biomarker [217]
OPRK1 TTQW87Y moderate Biomarker [218]
P2RY12 TTZ1DT0 moderate Biomarker [219]
PADI4 TTQHAXM moderate Biomarker [220]
PDE4A TTZ97H5 moderate Biomarker [221]
PDXP TT9UYG4 moderate Biomarker [222]
PEPD TTLZXI0 moderate Biomarker [142]
PGF TT48I1Y moderate Biomarker [223]
PLTP TTZF6SN moderate Biomarker [224]
PPARD TT2JWF6 moderate Biomarker [225]
PRDX5 TTLPJWH moderate Biomarker [226]
PTGIS TTLXKZR moderate Genetic Variation [227]
RENBP TTZCG0Q moderate Genetic Variation [228]
ROCK1 TTZN7RP moderate Biomarker [229]
SERPINF1 TTR59S1 moderate Biomarker [230]
SLC17A5 TTFSUIA moderate Biomarker [231]
SPHK2 TTCN0M9 moderate Biomarker [232]
SSTR4 TTAE1BR moderate Biomarker [112]
TH TTUHP71 moderate Biomarker [233]
TIRAP TTKU0LS moderate Biomarker [234]
TNFRSF11A TT3K9S2 moderate Biomarker [157]
TNFRSF17 TTZ3P4W moderate Biomarker [235]
TNFRSF1B TT63WSF moderate Biomarker [236]
TPSD1 TTNWD8O moderate Biomarker [237]
TYRP1 TTFRV98 moderate Altered Expression [238]
WDR5 TT7OFWB moderate Biomarker [239]
ABCA1 TTJW1GN Strong Biomarker [111]
ABCC9 TTEF5MJ Strong Biomarker [240]
ACAT1 TTK3C21 Strong Biomarker [241]
ACE2 TTUI5H7 Strong Biomarker [242]
ACLY TT0Z6Y2 Strong Biomarker [243]
ACVRL1 TTGYPTC Strong Genetic Variation [244]
ADAM10 TTVXEGU Strong Biomarker [245]
ADAMTS1 TTS2TEI Strong Biomarker [246]
ADAMTS13 TTUREBK Strong Genetic Variation [247]
ADGRL1 TTM5OJN Strong Biomarker [248]
ADK TTL732K Strong Genetic Variation [249]
ADM TTV14YH Strong Biomarker [250]
ADRA2A TTWG9A4 Strong Biomarker [251]
AGER TTMO9HF Strong Biomarker [252]
ALDH2 TTFLN4T Strong Genetic Variation [253]
ALOX12 TT12ABZ Strong Biomarker [254]
ALOX5 TTSJ6Q4 Strong Genetic Variation [255]
ANG TTURHFP Strong Biomarker [256]
ANGPT2 TTKLQTJ Strong Biomarker [257]
ANGPTL3 TT59GO7 Strong Biomarker [258]
ANPEP TTPHMWB Strong Biomarker [259]
AOC3 TT7HC21 Strong Biomarker [260]
APCS TTB7VAT Strong Biomarker [261]
APLN TT87D3J Strong Biomarker [262]
APLNR TTJ8E43 Strong Altered Expression [263]
APOA2 TTGQA9W Strong Biomarker [264]
APOB TTN1IE2 Strong Biomarker [265]
APOC3 TTXOZQ1 Strong Genetic Variation [266]
APOH TT2OUI9 Strong Genetic Variation [267]
APOL1 TTDB8PW Strong Genetic Variation [268]
AQP7 TTNGCRK Strong Biomarker [269]
ARG2 TTV1AG6 Strong Biomarker [270]
ASIC3 TTLGDIS Strong Biomarker [271]
ATG7 TTLVB9Z Strong Genetic Variation [249]
ATP4A TTF1QVM Strong Genetic Variation [272]
ATXN2 TTPQJ7P Strong Genetic Variation [249]
AVP TTJ8EWH Strong Biomarker [273]
BACE1 TTJUNZF Strong Genetic Variation [274]
BDKRB2 TTGY8IW Strong Genetic Variation [275]
BDNF TTSMLOH Strong Biomarker [276]
BGN TT0JPVF Strong Genetic Variation [277]
CACNA1D TT7RGTM Strong Genetic Variation [249]
CCL23 TTHAPJK Strong Biomarker [278]
CD320 TT0KV32 Strong Genetic Variation [279]
CD36 TTPJMCU Strong Altered Expression [280]
CD69 TTPQE9F Strong Genetic Variation [281]
CDC25C TTESBNC Strong Biomarker [282]
CDK8 TTBJR4L Strong Biomarker [283]
CEACAM1 TTA9CK4 Strong Biomarker [284]
CES1 TTMF541 Strong Biomarker [241]
CFB TTA0P7K Strong Biomarker [285]
CGA TTFC29G Strong Genetic Variation [286]
CHM TTOA18V Strong Genetic Variation [287]
CHRNA5 TTH2QRX Strong Biomarker [288]
CLCN3 TT8XNZ7 Strong Biomarker [289]
CLCN6 TTCJRDO Strong Genetic Variation [249]
CLCN7 TTST1AJ Strong Biomarker [290]
CNR2 TTMSFAW Strong Biomarker [291]
COMT TTKWFB8 Strong Biomarker [292]
CR1 TTEA8OW Strong Biomarker [293]
CRTC1 TT4GO0F Strong Genetic Variation [249]
CRY1 TT5MLZR Strong Biomarker [294]
CRYZ TTP6UO8 Strong Biomarker [295]
CTF1 TTXGTZU Strong Biomarker [296]
CXCL12 TT4UGTF Strong Genetic Variation [297]
CYP11B1 TTIQUX7 Strong Biomarker [298]
CYP11B2 TT9MNE2 Strong Biomarker [298]
CYP1B1 TTI84H7 Strong Biomarker [299]
CYP2C19 TTZ58XG Strong Genetic Variation [300]
CYP2C9 TTR40YJ Strong Genetic Variation [301]
CYP3A4 TTWP7HQ Strong Genetic Variation [302]
CYP3A5 TTHS0OK Strong Genetic Variation [303]
DAPK3 TTERVQN Strong Biomarker [304]
DBH TTYIP79 Strong Genetic Variation [249]
DCLK1 TTOHTCY Strong Biomarker [248]
DNMT1 TT6S2FE Strong Genetic Variation [249]
DPEP1 TTYUENF Strong Genetic Variation [249]
DPYSL2 TTZCW3T Strong Genetic Variation [249]
DRD4 TTE0A2F Strong Genetic Variation [305]
DYSF TTA7MXQ Strong Biomarker [306]
ECE1 TTQ9RYT Strong Biomarker [307]
EDN2 TTMR0OP Strong Genetic Variation [308]
EDNRA TTKRD0G Strong Biomarker [112]
EIF2AK2 TTXEZJ4 Strong Altered Expression [309]
ENPEP TT9PBIL Strong Genetic Variation [249]
ENPP1 TTZTIWS Strong Genetic Variation [310]
ENPP3 TTD4TKP Strong Biomarker [311]
EPHA1 TTLFZVU Strong Biomarker [312]
EPOR TTAUX24 Strong Biomarker [313]
F12 TTRJSMV Strong Genetic Variation [314]
F13A1 TTXI2RA Strong Genetic Variation [315]
F8 TT1290U Strong Altered Expression [316]
FABP4 TTHWMFZ Strong Biomarker [317]
FDFT1 TTFQEO5 Strong Genetic Variation [318]
FDXR TT3W4IX Strong Genetic Variation [319]
FER TTRA9G0 Strong Biomarker [320]
FES TTLBY21 Strong Genetic Variation [249]
FFAR2 TT0FYAN Strong Biomarker [321]
FGFR4 TT1KX2S Strong Biomarker [322]
FHL1 TTI7ENL Strong Genetic Variation [323]
FLNA TTSTRZY Strong Biomarker [324]
FOXC2 TTLBAP1 Strong Biomarker [325]
G3BP1 TTG0R8Z Strong Biomarker [326]
GAP43 TTSGLN5 Strong Altered Expression [327]
GAS6 TT69QD2 Strong Genetic Variation [328]
GCH1 TTLSWP6 Strong Biomarker [329]
GCK TTDLNGZ Strong Biomarker [330]
GDF2 TTAP4T1 Strong Biomarker [331]
GGH TTZJRL0 Strong Genetic Variation [332]
GIPR TTYMKBE Strong Biomarker [333]
GJA4 TTQO1VY Strong Biomarker [334]
GJA5 TTFQKZ7 Strong Altered Expression [335]
GJB6 TTAU8SJ Strong Biomarker [336]
GPR35 TT254XD Strong Biomarker [337]
GPR55 TTNET8J Strong Biomarker [338]
GPRC5D TTHRAPJ Strong Biomarker [339]
GPRC6A TTI1PRE Strong Biomarker [340]
GPX1 TTYAHBP Strong Genetic Variation [341]
GRIA1 TTVPQTF Strong Biomarker [342]
GRK3 TT5A4DX Strong Altered Expression [113]
GRK5 TTTCXO0 Strong Altered Expression [113]
HBEGF TT15SL0 Strong Altered Expression [343]
HGFAC TTD96RW Strong Genetic Variation [249]
HIPK2 TTOB49C Strong Genetic Variation [249]
HMGCR TTPADOQ Strong Biomarker [344]
HNF1A TT01M3K Strong Genetic Variation [345]
HNRNPA1 TTPJ9XK Strong Biomarker [346]
HPD TT8DSFC Strong Genetic Variation [347]
HRH1 TTTIBOJ Strong Altered Expression [348]
HSD11B1 TTN7BL9 Strong Biomarker [349]
HSD17B13 TTDJYZR Strong Genetic Variation [350]
HTT TTIWZ0O Strong Genetic Variation [351]
IDE TT2EDHU Strong Genetic Variation [352]
IGFBP3 TTZHNQA Strong Biomarker [353]
IL11 TTGUYTR Strong Biomarker [354]
IL18 TTRICUF Strong Genetic Variation [355]
IL18RAP TTZUJVE Strong Genetic Variation [356]
IL37 TTQTX98 Strong Biomarker [357]
INSR TTCBFJO Strong Genetic Variation [249]
IRS2 TTF95B8 Strong Biomarker [358]
JAK3 TTT7PJU Strong Genetic Variation [359]
KCNJ11 TT329V4 Strong Biomarker [360]
KCNJ5 TTEO25X Strong Genetic Variation [361]
KCNMA1 TTE87WJ Strong Genetic Variation [362]
KCNN4 TT7M9I6 Strong Biomarker [363]
KLKB1 TTN0PCX Strong Biomarker [364]
LDLR TTH0DUS Strong Biomarker [365]
LIPA TTS8T1M Strong Genetic Variation [366]
LIPE TTLUQ8E Strong Genetic Variation [367]
LPAR3 TTE2YJR Strong Biomarker [340]
LPL TTOF3WZ Strong Genetic Variation [368]
LRP6 TTSXOWE Strong Biomarker [369]
LTA4H TTXZEAJ Strong Biomarker [370]
LTB4R TTN53ZF Strong Biomarker [371]
LTC4S TTW7OTG Strong Genetic Variation [372]
MAD1L1 TTNE9U7 Strong Genetic Variation [249]
MAP3K3 TTJZNIG Strong Altered Expression [373]
MAP3K5 TTOQCD8 Strong Genetic Variation [374]
MAP4 TT0VFPN Strong Biomarker [375]
MAPK10 TT056SO Strong Genetic Variation [350]
MAPK7 TTU6FSC Strong Biomarker [376]
MAPK9 TT3IVG2 Strong Biomarker [377]
MAPKAP1 TTWDKCL Strong Biomarker [378]
MBL2 TTMQDZ5 Strong Biomarker [379]
MBTPS1 TTNSM2I Strong Biomarker [380]
MC3R TTNI91K Strong Genetic Variation [381]
MMP11 TTZW4MV Strong Altered Expression [382]
MRGPRX1 TTIX6PK Strong Biomarker [340]
MSTN TTM8I2X Strong Biomarker [383]
MYBPC3 TT9WOBN Strong Genetic Variation [249]
MYH7 TTNIMDP Strong Biomarker [384]
NAAA TTMN4HY Strong Genetic Variation [385]
NAALAD2 TTUWQLT Strong Genetic Variation [386]
NCF1 TTZ4JC3 Strong Biomarker [387]
NFKBIA TTSHAEB Strong Genetic Variation [249]
NISCH TT789FN Strong Altered Expression [388]
NLRP3 TT4EN8X Strong Altered Expression [389]
NOX4 TTQRBSJ Strong Biomarker [390]
NPPB TTY63XT Strong Altered Expression [391]
NPR1 TTM9IYA Strong Genetic Variation [249]
NPY TT64REZ Strong Biomarker [392]
NPY1R TTRK9JT Strong Genetic Variation [393]
NR1H4 TTS4UGC Strong Biomarker [394]
NR3C1 TTOZRK6 Strong Genetic Variation [395]
NR3C2 TT26PHO Strong Biomarker [396]
NR4A2 TT9HKN3 Strong Genetic Variation [397]
NRG4 TTWAGKJ Strong Biomarker [398]
OLR1 TTKSND3 Strong Biomarker [399]
OPRL1 TTNT7K8 Strong Genetic Variation [249]
OSMR TTAH0KM Strong Biomarker [400]
OXER1 TT7WBSV Strong Biomarker [340]
PAH TTGSVH2 Strong Genetic Variation [401]
PCSK7 TTD30LY Strong Biomarker [402]
PDE10A TTJW4LU Strong Genetic Variation [249]
PDE3A TT06AWU Strong Biomarker [403]
PDGFD TTSN0GA Strong Biomarker [404]
PDZK1 TTDTBLM Strong Genetic Variation [405]
PF4 TTSG7Q5 Strong Biomarker [406]
PKD2L1 TTAHD89 Strong Genetic Variation [249]
PLA2G2A TTO8QRU Strong Altered Expression [407]
PLA2G4A TTT1JVS Strong Altered Expression [408]
PLCB1 TTLPGU7 Strong Genetic Variation [249]
PLG TTP86E2 Strong Genetic Variation [409]
PLIN1 TTIV27N Strong Genetic Variation [367]
PLN TTMCVJF Strong Genetic Variation [410]
PNPLA3 TTEUAEH Strong Genetic Variation [411]
PPARGC1B TTKSQ3W Strong Biomarker [412]
PPID TTNAFOU Strong Biomarker [413]
PPIF TTRFQTB Strong Biomarker [413]
PREP TTNGKET Strong Biomarker [414]
PRG4 TTSKF4V Strong Biomarker [415]
PRKCD TT7A1BO Strong Genetic Variation [416]
PRKCE TT57MT2 Strong Genetic Variation [249]
PRKD1 TTSLUMT Strong Altered Expression [417]
PRKG1 TT7IZSA Strong Altered Expression [418]
PROC TTZUXYS Strong Genetic Variation [419]
PROKR1 TTB9CIL Strong Biomarker [420]
PROKR2 TTM67AX Strong Biomarker [420]
PSEN1 TTZ3S8C Strong Biomarker [421]
PTAFR TTQL5VC Strong Biomarker [422]
PTGER3 TTPNGDE Strong Biomarker [423]
PTGIR TTOFYT1 Strong Genetic Variation [424]
PTH TT6F7GZ Strong Genetic Variation [425]
RAPGEF3 TTOE7I0 Strong Altered Expression [426]
RAPGEF4 TTOS63B Strong Altered Expression [426]
RBP4 TT0C8BY Strong Biomarker [427]
RGS2 TTKB7T3 Strong Biomarker [428]
RIPK2 TTCQ2E5 Strong Biomarker [429]
RNF43 TTD91BL Strong Genetic Variation [249]
ROBO1 TTND1YP Strong Biomarker [430]
RORA TT1TYN7 Strong Genetic Variation [249]
ROS1 TTSZ6Y3 Strong Biomarker [431]
RPS6KA1 TTIXKA4 Strong Biomarker [432]
RYR1 TTU5CIX Strong Biomarker [433]
S100A9 TT0TMQG Strong Biomarker [146]
S1PR2 TTVSMOH Strong Genetic Variation [249]
SAA1 TTY0DN9 Strong Genetic Variation [434]
SCD TT6RIOV Strong Biomarker [213]
SCN2A TTLJTUF Strong Genetic Variation [435]
SELE TT1PL7M Strong Biomarker [436]
SELPLG TTS5K8U Strong Biomarker [437]
SENP1 TTW9HY5 Strong Biomarker [438]
SERPINH1 TTPSWQG Strong Altered Expression [439]
SFTPD TTGLMU7 Strong Biomarker [440]
SH2B3 TT36N7Z Strong Genetic Variation [249]
SIRT6 TTUXYWF Strong Biomarker [441]
SLC10A1 TTWZRY5 Strong Biomarker [442]
SLC12A3 TTP362L Strong Genetic Variation [443]
SLC1A5 TTF7WRM Strong Genetic Variation [444]
SLC22A12 TTA592U Strong Biomarker [445]
SLC22A2 TT0XOJN Strong Altered Expression [446]
SLC23A2 TTOP832 Strong Biomarker [447]
SLC29A1 TTLXAKE Strong Genetic Variation [448]
SLC2A9 TTIF3GB Strong Biomarker [449]
SLC5A1 TT2UE56 Strong Biomarker [450]
SLC6A7 TT9LGO5 Strong Biomarker [451]
SLC6A8 TTYUHB5 Strong Biomarker [117]
SLC7A1 TT4S150 Strong Genetic Variation [249]
SLC8A1 TTCF82X Strong Genetic Variation [452]
SLC9A1 TTGSEFH Strong Biomarker [453]
SLIT2 TTDWK85 Strong Biomarker [430]
SMYD2 TT7YJFO Strong Biomarker [454]
SOAT2 TTAK0IN Strong Biomarker [455]
SORT1 TTRX9AV Strong Genetic Variation [456]
SPRY1 TT0PSN6 Strong Biomarker [457]
TAGLN TTDRZ9H Strong Posttranslational Modification [458]
TERF1 TT1Y6J2 Strong Altered Expression [459]
TERF2 TT5XSLT Strong Genetic Variation [249]
THPO TTCG5PE Strong Biomarker [460]
TIAM1 TTNU6I5 Strong Biomarker [461]
TLR8 TT8CWFK Strong Biomarker [462]
TM6SF2 TTE1OHM Strong Genetic Variation [463]
TNC TTUCPMY Strong Genetic Variation [464]
TNFRSF11B TT2CJ75 Strong Biomarker [157]
TNFRSF25 TTDV6BQ Strong Genetic Variation [465]
TNFSF12 TTBTDM1 Strong Biomarker [466]
TNNI3 TTNLDK6 Strong Altered Expression [467]
TNNT2 TTWAS18 Strong Biomarker [468]
TPCN1 TTODQE2 Strong Biomarker [469]
TREM1 TTHZQP0 Strong Biomarker [470]
TRPC1 TTA76X0 Strong Biomarker [471]
TRPM4 TTJ2HKA Strong Biomarker [472]
TRPV2 TTBECWA Strong Biomarker [473]
TUBB1 TT63KYR Strong Genetic Variation [474]
TXNRD1 TTR7UJ3 Strong Biomarker [475]
TXNRD3 TTDYFVB Strong Biomarker [476]
UCP1 TTI12YJ Strong Biomarker [477]
UTS2 TTERU0T Strong Biomarker [250]
UTS2R TTW5UDX Strong Biomarker [478]
VCAM1 TTHCEF6 Strong Biomarker [479]
VDAC1 TTAMKGB Strong Biomarker [480]
VDR TTK59TV Strong Biomarker [481]
VEGFD TTOM5H4 Strong Biomarker [482]
WRN TT2H5WQ Strong Genetic Variation [249]
YES1 TT0SQ8J Strong Genetic Variation [249]
ADA TTLP57V Definitive Altered Expression [483]
------------------------------------------------------------------------------------
⏷ Show the Full List of 438 DTT(s)
This Disease Is Related to 17 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLCO6A1 DTIFXNS Limited Genetic Variation [484]
ABCB6 DTF9Y2V moderate Genetic Variation [485]
ABCC6 DT582KR moderate Genetic Variation [486]
SLC25A20 DTQOUM4 moderate Biomarker [174]
SLC2A2 DTUJPOL moderate Genetic Variation [487]
SLC35A1 DTVZIRG moderate Biomarker [488]
ABCA2 DTJ4NEG Strong Biomarker [489]
ATP12A DT5NLZA Strong Genetic Variation [272]
ATP2B1 DTJWQ1L Strong Genetic Variation [249]
CACNB2 DTBZWL4 Strong Genetic Variation [249]
SLC12A2 DTHKL3Q Strong Biomarker [490]
SLC17A4 DTHE530 Strong Genetic Variation [491]
SLC25A3 DTCRIWV Strong Biomarker [145]
SLC27A1 DTKDTML Strong Biomarker [492]
SLC27A6 DTG4CWJ Strong Biomarker [492]
SLC2A6 DTS4MKQ Strong Biomarker [445]
SLC9B1 DTR462N Strong Genetic Variation [249]
------------------------------------------------------------------------------------
⏷ Show the Full List of 17 DTP(s)
This Disease Is Related to 38 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
SI DE5EO4Y Limited Genetic Variation [134]
ACSS2 DEE76VW moderate Biomarker [493]
CYP7A1 DEDZRQ1 moderate Biomarker [494]
MSRA DEU2ZBY moderate Biomarker [495]
PSAT1 DEBS17P moderate Biomarker [130]
AKR1A1 DED2FW3 Strong Genetic Variation [496]
ALDH1A2 DEKN1H4 Strong Genetic Variation [497]
AOC2 DE8DP90 Strong Biomarker [498]
AS3MT DE9KJP3 Strong Genetic Variation [499]
CHST3 DEQIZP2 Strong Biomarker [500]
CYP27A1 DEBS639 Strong Altered Expression [501]
CYP2C18 DEZMWRE Strong Genetic Variation [301]
CYP4F2 DE3GT9C Strong Genetic Variation [502]
CYP4F3 DEFCMPI Strong Biomarker [301]
DDAH1 DEY0TQC Strong Biomarker [503]
DHCR7 DEL7GFA Strong Genetic Variation [504]
FAAH DEUM1EX Strong Biomarker [505]
FADS1 DE05S8C Strong Genetic Variation [506]
FMO3 DEP76YL Strong Biomarker [507]
GNPDA2 DEPJGQB Strong Genetic Variation [508]
HSD17B12 DE915QP Strong Genetic Variation [249]
MAT1A DEQ6NC9 Strong Genetic Variation [509]
MAT2B DEKF1OH Strong Biomarker [476]
MT1A DE5ME8A Strong Genetic Variation [510]
NADSYN1 DELF8BA Strong Genetic Variation [504]
NAT10 DEZV4AP Strong Biomarker [511]
NNMT DECVGJ3 Strong Genetic Variation [512]
NT5C2 DE1DOKJ Strong Genetic Variation [249]
PGPEP1 DEVDR46 Strong Genetic Variation [249]
PMM2 DEBRX3L Strong Altered Expression [513]
PON2 DEHJU7E Strong Biomarker [514]
PON3 DETXQZ1 Strong Altered Expression [515]
SAT1 DEMWO83 Strong Genetic Variation [142]
SCLY DEH4TD6 Strong Biomarker [516]
SULT1A1 DEYWLRK Strong Biomarker [517]
SULT1E1 DESTKG6 Strong Biomarker [518]
UBASH3B DE10BJ5 Strong Genetic Variation [249]
UGT1A6 DESD26P Strong Biomarker [519]
------------------------------------------------------------------------------------
⏷ Show the Full List of 38 DME(s)
This Disease Is Related to 556 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ABCG8 OTIJ76XW Limited Genetic Variation [249]
ANGPTL2 OTB6JG41 Limited Altered Expression [520]
ATP6AP2 OT0IABVV Limited Altered Expression [521]
CD180 OTITK5E6 Limited Biomarker [522]
CDKN2B OTAG24N1 Limited Genetic Variation [297]
COL9A1 OTWBR27Y Limited Biomarker [149]
COMP OTS2FPMI Limited Biomarker [149]
CP OTM8JE4Y Limited Biomarker [523]
CREM OTJIJ5AL Limited Biomarker [524]
ETV2 OTP5URZ8 Limited Biomarker [525]
FAM3B OTC2S91N Limited Biomarker [526]
FSD1 OT8P6PT3 Limited Biomarker [527]
FSD1L OTBQ48RF Limited Biomarker [527]
FSTL1 OT6KEZUD Limited Biomarker [528]
GNB3 OTA6HYBA Limited Genetic Variation [529]
GSTK1 OTDNGWAF Limited Genetic Variation [484]
HAVCR1 OT184CRZ Limited Biomarker [530]
IFI30 OT9DERT1 Limited Genetic Variation [531]
IMPACT OTQ923OB Limited Biomarker [532]
KIF6 OTDH3MR4 Limited Genetic Variation [533]
KLF15 OTGMQMVR Limited Biomarker [534]
KLF2 OTIP1UFX Limited Genetic Variation [535]
NTS OTPGDNQS Limited Altered Expression [536]
PLA2G6 OT5FL0WU Limited Altered Expression [537]
PPIG OTZ8BTTM Limited Genetic Variation [538]
PROS1 OTXQWNOI Limited Biomarker [130]
RMC1 OT7K8MTJ Limited Biomarker [539]
S100A1 OT1F2G4J Limited Genetic Variation [540]
SAA2 OTYAVJWG Limited Genetic Variation [434]
SELENOS OTUEWIU9 Limited Genetic Variation [541]
SERPINA5 OTTZXPGD Limited Biomarker [542]
SPX OTY3G4AR Limited Biomarker [543]
ACCS OTHIHI9D moderate Biomarker [493]
ADD1 OTTF68DC moderate Genetic Variation [544]
ADIPOR2 OT2HDTL8 moderate Genetic Variation [545]
AKAP1 OTIIB2JB moderate Biomarker [546]
AMPD1 OTU17BCI moderate Genetic Variation [547]
ANGPT4 OT881M3K moderate Biomarker [548]
ANGPTL1 OTXIN6V5 moderate Biomarker [548]
ANGPTL8 OTQFINCD moderate Biomarker [549]
ANXA7 OTLMD0TK moderate Genetic Variation [550]
APBB3 OTNUTR0N moderate Biomarker [211]
ARFGEF3 OTGQV0CU moderate Biomarker [239]
ARL2BP OT7REEDA moderate Genetic Variation [551]
ARTN OTWIWGL6 moderate Biomarker [167]
BMPR1A OTQOA4ZH moderate Biomarker [552]
BPIFB4 OTHF0EOJ moderate Altered Expression [553]
BSND OTYWZWPD moderate Genetic Variation [551]
C1QTNF6 OT57EPQC moderate Biomarker [554]
C1QTNF9 OTLI3VA3 moderate Biomarker [555]
CACUL1 OT6P1ZVP moderate Genetic Variation [556]
CALML6 OTHVPDSD moderate Genetic Variation [557]
CAPN10 OTS9LJW4 moderate Genetic Variation [558]
CETN1 OTGQ8JOZ moderate Genetic Variation [557]
COA3 OT4BMIYV moderate Genetic Variation [559]
COL4A2 OTJK1LKN moderate Genetic Variation [560]
COX8A OTU0NR39 moderate Biomarker [561]
CREG1 OTRHJ8HK moderate Biomarker [562]
CRYGD OTW29JC4 moderate Biomarker [563]
CXCL16 OTD49T9R moderate Biomarker [564]
DCDC2 OTSUFH1H moderate Genetic Variation [565]
DDAH2 OT8Q40G2 moderate Genetic Variation [566]
DHX40 OTOL02QN moderate Biomarker [220]
DNER OT2GH2E5 moderate Biomarker [567]
EFS OT06O7XL moderate Biomarker [568]
EPRS1 OTXK0FLB moderate Biomarker [569]
FBL OTRODIE5 moderate Biomarker [570]
FCGR3B OTSLSPZG moderate Biomarker [189]
FHL2 OT0OAYWT moderate Biomarker [571]
FLAD1 OTY8R02L moderate Biomarker [213]
FNDC5 OT5CSK9X moderate Biomarker [572]
GADD45G OT8V1J4M moderate Biomarker [573]
GAL3ST1 OTSFFZRD moderate Biomarker [488]
GDF11 OTOSNMND moderate Altered Expression [574]
GOT2 OT6XBWN0 moderate Biomarker [575]
GPIHBP1 OTDF8R2M moderate Biomarker [576]
GPR42 OTEB0ROY moderate Biomarker [112]
HABP2 OTAUIPW0 moderate Genetic Variation [577]
HOXD13 OTWSC8TF moderate Biomarker [578]
HSF4 OT1UX9SK moderate Biomarker [579]
HSPA1A OTKGIE76 moderate Genetic Variation [580]
HSPB2 OTS01646 moderate Altered Expression [197]
INSRR OT3F75WA moderate Genetic Variation [581]
KDM5D OTEKG0KD moderate Altered Expression [582]
MFAP1 OTZN4FT3 moderate Genetic Variation [583]
MMRN1 OT7ZNYHT moderate Biomarker [584]
NIBAN2 OTVDQSPI moderate Biomarker [585]
NOX1 OTZPJQCC moderate Biomarker [586]
NOX5 OTHTH59G moderate Biomarker [390]
NPPA OTMQNTNX moderate Biomarker [587]
PAPPA OTTTG9PG moderate Biomarker [588]
PEAR1 OT2XLTB2 moderate Biomarker [589]
PHACTR1 OTAMPX9V moderate Biomarker [590]
PIP OTH719AH moderate Biomarker [591]
PLA2G10 OTRZ2L5A moderate Altered Expression [407]
PLA2G15 OT6VJTPA moderate Biomarker [493]
PLAG1 OTT9AJQY moderate Biomarker [130]
PPM1K OTNZ4N4E moderate Genetic Variation [592]
PPP6R3 OTIXD60Q moderate Biomarker [593]
RAPSN OTGMSWDQ moderate Genetic Variation [188]
RFC1 OT3L5PK3 moderate Genetic Variation [594]
RIPOR2 OTXB6LIR moderate Biomarker [595]
RNF10 OTF7Y6M7 moderate Biomarker [596]
RPE OT0XT3JU moderate Biomarker [597]
SELENOP OT02B8IR moderate Altered Expression [541]
SHMT1 OTIINA3J moderate Biomarker [279]
SLC22A18 OT9C3KR4 moderate Biomarker [598]
SOD3 OTIOZQAB moderate Biomarker [599]
SRA1 OTYOGMTG moderate Biomarker [211]
TBPL1 OT4I143E moderate Altered Expression [238]
TBX20 OTMPU2XQ moderate Altered Expression [600]
TES OTL8PP6V moderate Biomarker [601]
TM7SF2 OTILU5S7 moderate Biomarker [115]
TMEM54 OTPQEFR0 moderate Genetic Variation [556]
TOR2A OT1EGCDU moderate Biomarker [602]
TRIB1 OTPEO17G moderate Genetic Variation [603]
TRIB3 OTG5OS7X moderate Genetic Variation [604]
A2M OTFTX90K Strong Biomarker [605]
AAAS OTJT9T23 Strong Genetic Variation [606]
AAGAB OTRGGM2Z Strong Genetic Variation [249]
ABCF3 OTLBYTTN Strong Genetic Variation [249]
ABHD17C OTB1MTOI Strong Genetic Variation [249]
ABHD5 OTY829Z3 Strong Genetic Variation [367]
ABI2 OT8GIIS5 Strong Biomarker [607]
ACACA OT5CQPZY Strong Genetic Variation [608]
ACAN OTUOCW8K Strong Biomarker [246]
ACD OTC54EPO Strong Biomarker [609]
ACOX2 OT3VH359 Strong Altered Expression [610]
ACP1 OTJ9CKLU Strong Genetic Variation [611]
ACSM3 OT0AE1IV Strong Biomarker [612]
ACTRT1 OTHFKSIZ Strong Biomarker [607]
ACYP2 OTRB4S6X Strong Genetic Variation [342]
ADAM11 OTPTVW5W Strong Biomarker [613]
ADCY9 OT1IZT5K Strong Genetic Variation [249]
ADO OTRLGQ7V Strong Genetic Variation [249]
ADTRP OTFI2BQX Strong Altered Expression [614]
AGAP1 OTVX8835 Strong Genetic Variation [615]
AGBL2 OTCX9987 Strong Biomarker [616]
AHRR OTSJ12W6 Strong Genetic Variation [185]
AIP OTDJ3OSV Strong Biomarker [320]
ALDH7A1 OTV57BZD Strong Biomarker [617]
ALDH9A1 OTNWHUJ1 Strong Genetic Variation [618]
ALG9 OT5V9PIR Strong Genetic Variation [249]
ALKBH1 OTADGU5D Strong Biomarker [619]
AMBP OTLU8GU8 Strong Genetic Variation [620]
ANK2 OTWB4R1Y Strong Biomarker [621]
ANKRD1 OTHJ7JV9 Strong Biomarker [622]
ANO5 OTOW8R6H Strong Genetic Variation [497]
AP1G2 OTTJ7NXL Strong Genetic Variation [342]
APOA5 OTEVKLVA Strong Genetic Variation [623]
APOC1 OTA58CED Strong Biomarker [624]
APOC2 OTLINYIQ Strong Biomarker [625]
APOL6 OTYTBJEG Strong Biomarker [626]
APOLD1 OTGJ4X9N Strong Genetic Variation [249]
ARHGAP42 OTIDSJMK Strong Genetic Variation [249]
ARHGEF1 OTXU4HBW Strong Biomarker [627]
ARHGEF5 OTUVGFT9 Strong Altered Expression [210]
ARID4B OTYLPILE Strong Biomarker [628]
ARID5B OTUQ4CQY Strong Altered Expression [629]
ARL15 OT00YSWZ Strong Genetic Variation [249]
ARL6IP1 OT536XAV Strong Biomarker [607]
ARMS2 OTUXHJ9H Strong Genetic Variation [630]
ARSD OTAHW9M8 Strong Genetic Variation [631]
ARSI OTIANNWW Strong Biomarker [632]
ATF7IP OTU6ZA7F Strong Genetic Variation [633]
ATL1 OTR2788Y Strong Genetic Variation [249]
ATP5PF OTDAE8FP Strong Biomarker [634]
ATRNL1 OTY5JUX2 Strong Biomarker [511]
AXIN1 OTRGZGZ5 Strong Genetic Variation [249]
BAG3 OTVXYUDQ Strong Biomarker [635]
BAHCC1 OTP41L1D Strong Genetic Variation [249]
BANK1 OTXAAA11 Strong Genetic Variation [249]
BBS1 OTXSXB1K Strong Genetic Variation [636]
BCAS3 OTDVAX6B Strong Genetic Variation [249]
BCL11B OT8KKCVJ Strong Genetic Variation [637]
BCL3 OT1M5B95 Strong Biomarker [638]
BEAN1 OT0WLH27 Strong Biomarker [639]
BEST1 OTWHE1ZC Strong Biomarker [640]
BHMT OTYB6PXZ Strong Genetic Variation [641]
BICC1 OTYRKIJ1 Strong Genetic Variation [249]
BID OTOSHSHU Strong Biomarker [642]
BMS1 OTEGQ8ZO Strong Genetic Variation [608]
BRAP OTB7BAFQ Strong Genetic Variation [643]
BTBD8 OT3A3RD7 Strong Genetic Variation [644]
C1GALT1 OT2ZSZ6P Strong Genetic Variation [249]
C1QL1 OTNQ0G3E Strong Biomarker [645]
C1QTNF12 OTFAIQHR Strong Biomarker [646]
C1QTNF3 OTOJMWW0 Strong Biomarker [647]
C1QTNF4 OTHD4Y9D Strong Genetic Variation [249]
C22orf31 OTHL20YA Strong Genetic Variation [249]
CABCOCO1 OTNFEBKR Strong Genetic Variation [249]
CADPS2 OTV1FW0M Strong Genetic Variation [249]
CAMTA1 OTAN1S5B Strong Genetic Variation [648]
CAPN5 OTQ8QM7K Strong Biomarker [649]
CARD8 OTXXZYWU Strong Genetic Variation [650]
CASZ1 OTWJ2OR8 Strong Genetic Variation [249]
CAV3 OTWSFDB4 Strong Biomarker [306]
CCDC148 OTAU2Y3S Strong Genetic Variation [249]
CCDC170 OTNQOJ6S Strong Genetic Variation [249]
CCHCR1 OT22C116 Strong Biomarker [651]
CCL27 OTUZYC61 Strong Biomarker [511]
CCL7 OTDIS99H Strong Biomarker [652]
CCN6 OTRFHQ2Z Strong Genetic Variation [347]
CCND2 OTDULQF9 Strong Genetic Variation [249]
CCRL2 OT5PX0RX Strong Altered Expression [653]
CD5L OTPY4WQR Strong Genetic Variation [281]
CDCA5 OTZLCQ5U Strong Genetic Variation [249]
CDKAL1 OTA0SGNE Strong Genetic Variation [249]
CEBPD OTNBIPMY Strong Biomarker [654]
CELSR2 OTON6JSZ Strong Genetic Variation [249]
CENPC OTVJ6VE9 Strong Altered Expression [655]
CERS2 OTRAHYYP Strong Genetic Variation [656]
CERT1 OTNUCNHX Strong Genetic Variation [249]
CFDP1 OTXY7J96 Strong Genetic Variation [249]
CHD8 OTS7A6AF Strong Genetic Variation [657]
CHGB OT7SAQT2 Strong Genetic Variation [658]
CILP2 OTAFSWG1 Strong Genetic Variation [659]
CISD1 OT0MTVGF Strong Biomarker [660]
CLDND1 OTGECYGG Strong Altered Expression [661]
CLUAP1 OTESP4WL Strong Genetic Variation [249]
CMIP OTZN8Z4A Strong Genetic Variation [249]
CNDP1 OTOYSQG7 Strong Genetic Variation [662]
CNOT1 OTTEU05F Strong Genetic Variation [663]
COG2 OTKQH4N4 Strong Genetic Variation [664]
COL4A1 OTL6D1YE Strong Genetic Variation [249]
COL5A1 OT24078H Strong Genetic Variation [665]
COL5A2 OT5VOSQE Strong Biomarker [666]
COL9A2 OT1ZBDBV Strong Biomarker [149]
COL9A3 OTCUJOEK Strong Biomarker [149]
COMMD7 OTWWJ97D Strong Genetic Variation [667]
COPS8 OTNAD2S4 Strong Genetic Variation [668]
CORIN OT4SK7DK Strong Biomarker [669]
CORT OTX3GUHB Strong Biomarker [670]
COX1 OTG3O9BN Strong Altered Expression [671]
COX5A OTP0961M Strong Biomarker [672]
CPEB2 OTKES4YR Strong Genetic Variation [249]
CRIM1 OTTZNV6Y Strong Biomarker [673]
CRISP2 OT8HLTV5 Strong Biomarker [674]
CSN2 OT22C0PD Strong Genetic Variation [675]
CSN3 OTR61MI8 Strong Genetic Variation [362]
CSTB OT3U0JF8 Strong Biomarker [676]
CTRL OTB6NA5O Strong Genetic Variation [677]
CXCL5 OTZOUPCA Strong Biomarker [678]
CYBA OT16N9ZO Strong Genetic Variation [679]
CYGB OTX153DQ Strong Altered Expression [680]
CYTB OTAHB98A Strong Genetic Variation [681]
DAB2IP OTF456VC Strong Biomarker [607]
DACH1 OTMKNAGG Strong Genetic Variation [682]
DCUN1D5 OTHPMYHX Strong Genetic Variation [249]
DDT OTF5HTYL Strong Altered Expression [655]
DDX23 OTBJHS8C Strong Genetic Variation [249]
DECR1 OTCDIR6X Strong Biomarker [683]
DEGS1 OT4WXPKW Strong Biomarker [684]
DLEU7 OTVKX1YP Strong Genetic Variation [249]
DLG2 OTQ3BD8U Strong Genetic Variation [249]
DNAJB9 OT38EQT6 Strong Biomarker [685]
DOCK7 OTINNVQV Strong Genetic Variation [249]
DSE OTQ108VJ Strong Genetic Variation [686]
DYM OTQ670WI Strong Biomarker [687]
EBF1 OTZ61YYH Strong Genetic Variation [249]
EBF2 OTFWZE51 Strong Genetic Variation [249]
ECHDC3 OTKU2RMC Strong Altered Expression [688]
EEF1A1 OT00THXS Strong Biomarker [689]
EFCAB13 OTYZ859V Strong Genetic Variation [249]
EFNB2 OT0DCUOM Strong Biomarker [690]
ELMO1 OTY2ORXK Strong Biomarker [168]
ELN OTFSO7PG Strong Biomarker [691]
ENHO OT91QASK Strong Biomarker [692]
ERCC3 OTVAW3P1 Strong Biomarker [693]
ERG OTOTX9VU Strong Genetic Variation [694]
ESM1 OT331Y8V Strong Biomarker [695]
ESS2 OTZ08VCZ Strong Genetic Variation [696]
ETV3 OTEN03BM Strong Genetic Variation [697]
FANCD2 OTVEB5LF Strong Genetic Variation [618]
FBLN1 OT5MHHOP Strong Biomarker [698]
FBLN5 OTLVNZ8U Strong Altered Expression [699]
FBN2 OT3KYJQL Strong Genetic Variation [608]
FBRS OTUVH446 Strong Altered Expression [700]
FBXO8 OTZNGJGW Strong Altered Expression [700]
FGA OTMIHY80 Strong Biomarker [190]
FGB OT6RKLI9 Strong Genetic Variation [234]
FGD5 OT5VIRP2 Strong Genetic Variation [249]
FLNC OT3F8J6Y Strong Biomarker [701]
FLT3LG OTU0YGC4 Strong Biomarker [702]
FOXO4 OT90X9LN Strong Biomarker [703]
FREM1 OTMHRV87 Strong Genetic Variation [249]
FRMD3 OT0CD2GG Strong Biomarker [168]
FUNDC1 OTA6IVKQ Strong Biomarker [704]
FUT2 OTLXM6WI Strong Genetic Variation [249]
FZD4 OTGLZIE0 Strong Biomarker [340]
GABPA OT9YB2SA Strong Genetic Variation [705]
GALNT4 OT6WKC13 Strong Genetic Variation [517]
GCA OTAJ7ZHG Strong Biomarker [706]
GCKR OTSIWXGG Strong Genetic Variation [249]
GDF10 OTEVXGJ7 Strong Biomarker [707]
GIT2 OTQ2EQJ1 Strong Genetic Variation [249]
GLYAT OT3WWYXD Strong Genetic Variation [249]
GMFG OTMPNSE7 Strong Biomarker [708]
GML OTHKIB62 Strong Genetic Variation [249]
GOLGA6A OTHU9MRX Strong Biomarker [709]
GOSR2 OTYHIYN2 Strong Genetic Variation [249]
GP5 OT3WGPR3 Strong Biomarker [710]
GPC6 OTNJBESF Strong Biomarker [690]
GPR15 OTK8674M Strong Genetic Variation [711]
GPR151 OT7EACU6 Strong Biomarker [340]
GPR75 OT8SPUGC Strong Biomarker [712]
GPRC5C OT45AJT3 Strong Biomarker [339]
GPX3 OT6PK94R Strong Biomarker [713]
GTF2I OTUYL1TQ Strong Genetic Variation [249]
GUCY1A1 OTPTCBUN Strong Genetic Variation [249]
H6PD OTO7TNDD Strong Genetic Variation [714]
HBA1 OTW2BQF4 Strong Biomarker [715]
HDLBP OTKDEEYX Strong Biomarker [716]
HEATR6 OTD3MYS0 Strong Biomarker [717]
HGS OTCYYCAC Strong Biomarker [718]
HHIPL1 OT3GMU2X Strong Biomarker [719]
HIBADH OTCMMMIZ Strong Genetic Variation [249]
HIVEP2 OTVOMCW4 Strong Genetic Variation [249]
HOPX OTBSR6C9 Strong Genetic Variation [720]
HOXB3 OT9UC5PE Strong Genetic Variation [249]
HOXB5 OTU74TB8 Strong Genetic Variation [249]
HOXC4 OT52VJ6V Strong Genetic Variation [249]
HPR OTXSC9UB Strong Genetic Variation [249]
HRCT1 OTNZVQWX Strong Genetic Variation [249]
HS1BP3 OT5NSZJ1 Strong Genetic Variation [249]
HSF2BP OTWKP0JC Strong Genetic Variation [249]
HSPA14 OTZCA5LK Strong Biomarker [198]
HSPA2 OTSDET7B Strong Genetic Variation [580]
IGF2BP2 OT4ZSEEE Strong Genetic Variation [721]
IGFALS OTTWCZYM Strong Genetic Variation [722]
IGFBP4 OT2HZRBD Strong Genetic Variation [199]
IL1RAPL1 OTW3T4B2 Strong Genetic Variation [723]
INPP5A OT9CMGMS Strong Genetic Variation [249]
INPP5K OTQFLQKA Strong Biomarker [724]
INSIG2 OTX4VY51 Strong Genetic Variation [725]
IQGAP1 OTZRWTGA Strong Biomarker [346]
IRF6 OTKJ44EV Strong Biomarker [724]
IRX4 OT0TV6WK Strong Genetic Variation [274]
ITGB4 OT28UK84 Strong Biomarker [726]
JCAD OT7G1WJW Strong Biomarker [727]
JPH2 OTL9YH7V Strong Genetic Variation [249]
JPH3 OTHTJO2I Strong Biomarker [728]
KALRN OT8WRCBH Strong Genetic Variation [729]
KANK2 OT3SZIWM Strong Genetic Variation [249]
KCNE1 OTZNQUW9 Strong Biomarker [730]
KCNIP3 OTCQPEM4 Strong Biomarker [731]
KCTD1 OT89U5MB Strong Genetic Variation [342]
KCTD15 OTM6L4A0 Strong Genetic Variation [508]
KDM2B OTDMCVW7 Strong Genetic Variation [249]
KL OTD4VWU6 Strong Biomarker [732]
KLF14 OT8BXLBS Strong Biomarker [733]
KLF3 OTIIAC18 Strong Biomarker [734]
KLF5 OT1ABI9N Strong Biomarker [735]
KLK11 OT5PKX7Y Strong Biomarker [736]
KPNA4 OTP0EX18 Strong Genetic Variation [249]
LCORL OTJNQRC5 Strong Genetic Variation [249]
LGALS3BP OT9AGQKH Strong Biomarker [737]
LGR6 OTPZ1PWR Strong Biomarker [340]
LHFPL2 OTDWEEBQ Strong Genetic Variation [249]
LIMA1 OTONPC9R Strong Genetic Variation [249]
LIN54 OTPC9LQI Strong Genetic Variation [249]
LIPC OTZY5SC9 Strong Biomarker [738]
LOXL1 OTA0NEJU Strong Genetic Variation [739]
LPIN1 OTQ75KF2 Strong Genetic Variation [740]
LRIG1 OTY5HZN5 Strong Biomarker [491]
LRP8 OTZ71YV2 Strong Genetic Variation [741]
LRPAP1 OT6DVD2Q Strong Genetic Variation [742]
LSP1 OTSPSIFO Strong Genetic Variation [249]
LSR OTR8Y32X Strong Altered Expression [743]
LYPD4 OTYNO8BS Strong Genetic Variation [744]
MACROD1 OTWFEVRW Strong Genetic Variation [249]
MAGI2 OTXDDKZS Strong Biomarker [607]
MARCHF5 OTBK6BBM Strong Biomarker [745]
MASP1 OTWWCNZP Strong Biomarker [746]
MB OTYWYL2D Strong Biomarker [747]
MBOAT7 OTHRCBLK Strong Genetic Variation [748]
MCF2L OTEURA8N Strong Genetic Variation [249]
MECOM OTP983W8 Strong Genetic Variation [249]
MED15 OT0D0JVD Strong Biomarker [283]
MED23 OTKZQT0R Strong Biomarker [503]
MEF2A OTV2SF6E Strong Genetic Variation [749]
MEIS1 OTH9DKAD Strong Genetic Variation [750]
MEPE OTXJRUW0 Strong Genetic Variation [751]
MFAP4 OT5W64QY Strong Biomarker [752]
MIA3 OTBVIZQD Strong Genetic Variation [297]
MLC1 OTCNZLSP Strong Biomarker [753]
MLXIPL OTR9MLLW Strong Genetic Variation [754]
MPI OTBH6ZK1 Strong Altered Expression [513]
MRAS OTNCVCQW Strong Genetic Variation [249]
MRGPRX3 OTRKCCDS Strong Biomarker [340]
MRGPRX4 OTOBHZVA Strong Biomarker [340]
MT1B OTUA4FFH Strong Biomarker [755]
MTCH2 OTV3E4GU Strong Genetic Variation [508]
MXD3 OT4U88UP Strong Genetic Variation [249]
MXI1 OTUQ9E0D Strong Genetic Variation [249]
MYEOV OTDC7UHL Strong Genetic Variation [249]
MYO9B OTQ94R5K Strong Genetic Variation [249]
MYOCD OTSJNHTH Strong Biomarker [756]
MYOD1 OTV2S79X Strong Biomarker [757]
NAA38 OTI8VWK3 Strong Genetic Variation [249]
NANOS3 OTGX9IQU Strong Biomarker [758]
NAV1 OT667KTL Strong Genetic Variation [249]
NBN OT73B5MD Strong Biomarker [759]
NCALD OTJZ8UEL Strong Genetic Variation [249]
ND5 OT45LW1K Strong Genetic Variation [681]
NDUFAF6 OTRJMIGT Strong Genetic Variation [249]
NEDD4L OT1B19RU Strong Genetic Variation [760]
NFATC2 OTK5T6HZ Strong Genetic Variation [249]
NHS OTKE8QAT Strong Genetic Variation [761]
NKAIN4 OT91HOEP Strong Genetic Variation [274]
NKX2-5 OTS1SAWM Strong Biomarker [762]
NMT1 OT42GQ3D Strong Genetic Variation [249]
NOS1AP OTDFOBRU Strong Biomarker [763]
NPC1 OTRIPICX Strong Genetic Variation [249]
NPNT OTFZAO1G Strong Genetic Variation [249]
NPS OTEG25A2 Strong Biomarker [764]
NRM OTK7F9XZ Strong Genetic Variation [765]
NSD2 OTQ6SW4R Strong Biomarker [766]
NUCB2 OTHO6JWN Strong Altered Expression [767]
OGA OT7ZBWT1 Strong Biomarker [768]
OGN OTKP5S4L Strong Biomarker [769]
OGT OT1Z1ZXE Strong Biomarker [770]
OMA1 OT0JRVY7 Strong Biomarker [771]
OR10AD1 OTCVPVQ0 Strong Genetic Variation [249]
OSBPL11 OTU2IC5O Strong Genetic Variation [772]
OXA1L OTS0BFRD Strong Biomarker [773]
PACSIN2 OTC2R00C Strong Biomarker [774]
PAGR1 OTXR5PQ8 Strong Genetic Variation [775]
PALM2AKAP2 OTI618VF Strong Genetic Variation [249]
PAQR5 OTGGWXQE Strong Genetic Variation [249]
PAQR7 OTIWX5AM Strong Genetic Variation [776]
PAX2 OTKP1N8F Strong Genetic Variation [249]
PC OT6O0V51 Strong Biomarker [777]
PCBP1 OTHN0TD7 Strong Altered Expression [778]
PCLAF OTMVIOUU Strong Biomarker [511]
PCYOX1 OT8FBKY0 Strong Biomarker [779]
PDCD6IP OTS8T6A7 Strong Biomarker [607]
PDILT OT5D60QU Strong Genetic Variation [249]
PDLIM3 OTVXQC81 Strong Biomarker [511]
PER2 OTU2B1DJ Strong Biomarker [780]
PHF13 OT89FV4A Strong Genetic Variation [249]
PHLPP1 OTIFXW8D Strong Biomarker [781]
PINK1 OT50NR57 Strong Biomarker [595]
PITX2 OTWMXAOY Strong Genetic Variation [782]
PKHD1 OTAH8SMF Strong Genetic Variation [249]
PLCE1 OTJISZOX Strong Genetic Variation [249]
PLEKHG1 OTDVYW2F Strong Genetic Variation [249]
PLPP3 OTSSF7BK Strong Genetic Variation [249]
PLXNA3 OTMZIBVG Strong Biomarker [342]
PNKD OT6G9UXN Strong Genetic Variation [249]
PNPLA2 OTR3ERMR Strong Genetic Variation [367]
PODXL OTPNQXF3 Strong Biomarker [783]
POU2F3 OTIOOJWD Strong Genetic Variation [784]
PPIH OTB3HCLB Strong Biomarker [785]
PPP6R2 OTERHESI Strong Genetic Variation [644]
PRDM16 OT0BGA27 Strong Genetic Variation [249]
PRDM6 OTKY12D9 Strong Genetic Variation [249]
PRDX3 OTLB2WEU Strong Biomarker [786]
PREX1 OTUTPVA9 Strong Genetic Variation [249]
PRKAG2 OTHTAM54 Strong Genetic Variation [787]
PRKAR2A OTZ7P17Z Strong Biomarker [420]
PRM3 OT6574BF Strong Genetic Variation [788]
PRMT6 OT5V3XIN Strong Altered Expression [789]
PROCR OTRHED17 Strong Biomarker [790]
PSMA6 OTJ6RPX5 Strong Genetic Variation [791]
PTCRA OTQTO5QZ Strong Genetic Variation [184]
PTPA OTRGFOI7 Strong Biomarker [792]
PTPRU OTHDO0QG Strong Biomarker [145]
PTX3 OTPXHRKU Strong Biomarker [793]
PXDN OTFGGM9R Strong Biomarker [794]
RAPGEF5 OT53VS75 Strong Biomarker [795]
RARRES2 OT1BJE8K Strong Biomarker [796]
RASGRF1 OTNWJ7EN Strong Biomarker [461]
RCBTB1 OTAYELI8 Strong Biomarker [709]
REG1A OTMHUH1D Strong Biomarker [594]
REM1 OTUXL0HC Strong Biomarker [797]
RERE OT3G4GBZ Strong Genetic Variation [249]
REXO1 OTZT6RAW Strong Genetic Variation [249]
RGL3 OTWZ30EZ Strong Genetic Variation [249]
RGS5 OTUY0Q2I Strong Genetic Variation [798]
RHOD OTALMEIN Strong Altered Expression [799]
RLN2 OTY3OG71 Strong Biomarker [800]
RNASE1 OTKZ7CO9 Strong Biomarker [801]
RNF214 OTU07O6U Strong Genetic Variation [274]
RPS6 OTT4D1LN Strong Genetic Variation [249]
RUVBL1 OTWV19L7 Strong Genetic Variation [249]
RYR2 OT0PF19E Strong Biomarker [433]
RYR3 OT4EHIP4 Strong Genetic Variation [802]
SAG OTDNS3ZQ Strong Genetic Variation [803]
SAMM50 OTRYFYIU Strong Genetic Variation [350]
SCAF1 OT16TM3N Strong Genetic Variation [249]
SELENBP1 OT3NZNTR Strong Biomarker [651]
SEPTIN4 OTD16B30 Strong Biomarker [804]
SEPTIN9 OT1VMRFQ Strong Genetic Variation [249]
SERP1 OT60XXUP Strong Biomarker [805]
SERPINB2 OT72QLZB Strong Genetic Variation [806]
SFRP5 OTLCVVSH Strong Biomarker [807]
SFTPA1 OT87XL1U Strong Biomarker [808]
SFTPA2 OT6SFOMU Strong Biomarker [808]
SHC1 OT1J5IRN Strong Genetic Variation [809]
SIRT7 OT5M4OT4 Strong Biomarker [810]
SLC22A24 OTNVZ8Z1 Strong Genetic Variation [811]
SLC35E3 OTZD8TQS Strong Altered Expression [812]
SMS OT8JYKNH Strong Genetic Variation [813]
SMUG1 OT2YIOCQ Strong Biomarker [814]
SOCS2 OTBPNKJQ Strong Biomarker [815]
SORBS1 OTWH8762 Strong Genetic Variation [249]
SORCS3 OT4VOMBC Strong Genetic Variation [249]
SORL1 OTQ8FFNS Strong Biomarker [816]
SOS2 OTV3XRE5 Strong Genetic Variation [249]
SOX6 OTT0W0LE Strong Genetic Variation [249]
SPIRE1 OTOQWRLA Strong Genetic Variation [817]
SPON2 OTE7JLNM Strong Biomarker [818]
SPRED2 OTUX685J Strong Altered Expression [819]
SPRY2 OTH0CRCZ Strong Biomarker [457]
SPTBN4 OTAJAVP9 Strong Biomarker [820]
SPTBN5 OT8MUQDU Strong Genetic Variation [249]
SRM OT4N5MDP Strong Biomarker [821]
SSB OTCCTPBR Strong Biomarker [822]
ST13 OTNML6UP Strong Genetic Variation [720]
STAT2 OTO9G2RZ Strong Altered Expression [823]
STIP1 OT7TXLOX Strong Genetic Variation [720]
STK25 OT4YPNTF Strong Biomarker [824]
STN1 OT8UWRA3 Strong Biomarker [825]
STOX1 OTED3YVO Strong Genetic Variation [826]
SVEP1 OTOBICRD Strong Genetic Variation [249]
SWAP70 OTPHT2QD Strong Genetic Variation [249]
SYNPO2 OTC3U0YH Strong Biomarker [827]
SZT2 OTB4FVP4 Strong Biomarker [605]
TANGO2 OTT9UI89 Strong Genetic Variation [249]
TAS2R38 OTX5MM36 Strong Genetic Variation [828]
TAS2R50 OTPRMVZW Strong Genetic Variation [829]
TAT OT2CJ91O Strong Biomarker [830]
TBATA OTGDMAAL Strong Biomarker [831]
TBC1D19 OTLMQ1KS Strong Genetic Variation [249]
TCHP OTVDMHSY Strong Genetic Variation [249]
TFR2 OTMYCCEO Strong Biomarker [832]
THADA OTYZQX0F Strong Genetic Variation [249]
THAP9 OTY4TSJO Strong Genetic Variation [249]
THBS4 OTA1T9KK Strong Genetic Variation [833]
TIMD4 OTGGC20G Strong Genetic Variation [249]
TIMELESS OTD8DCBJ Strong Altered Expression [210]
TIMP4 OT8A68SW Strong Altered Expression [834]
TMBIM1 OTE47B57 Strong Genetic Variation [249]
TMEM11 OTL9HDEY Strong Altered Expression [513]
TMEM43 OTM9RS9G Strong Biomarker [835]
TNFAIP6 OT1SLUZH Strong Biomarker [836]
TNFAIP8L2 OTII0RM0 Strong Biomarker [837]
TNRC6C OTBR07PM Strong Genetic Variation [444]
TRAF1 OTTLM5RU Strong Biomarker [838]
TRAF3IP2 OTLLZERL Strong Genetic Variation [839]
TRDMT1 OTAYQ8ZF Strong Biomarker [279]
TRIM21 OTA4UJCF Strong Genetic Variation [840]
TSC22D3 OT03UM03 Strong Altered Expression [841]
TTC7B OTUE51B3 Strong Genetic Variation [842]
NUP155 OTIIAH4E Definitive Altered Expression [843]
------------------------------------------------------------------------------------
⏷ Show the Full List of 556 DOT(s)

References

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2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
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5 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
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8 Clinical pipeline report, company report or official report of CardioPharma Wilmington.
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23 ClinicalTrials.gov (NCT02490202) Efficacy and Safety of SANGUINATE for Reduction of Delayed Graft Function in Patients Receiving a Kidney Transplant.
24 ClinicalTrials.gov (NCT00103519) Study of DITPA in Patients With Congestive Heart Failure. U.S. National Institutes of Health.
25 ClinicalTrials.gov (NCT02160626) Dose-Response Profile of A-101 in Subjects With Seborrheic Keratosis. U.S. National Institutes of Health.
26 ClinicalTrials.gov (NCT00132470) Treatment With AX200 for Acute Ischemic Stroke. U.S. National Institutes of Health.
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36 ClinicalTrials.gov (NCT01890967) A Study of LY3015014 in Participants With High Cholesterol. U.S. National Institutes of Health.
37 ClinicalTrials.gov (NCT05563246) KRAKEN: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Oral Once-Daily LY3473329 in Adults With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events. U.S.National Institutes of Health.
38 ClinicalTrials.gov (NCT04610892) A Phase IIB, Randomized, Double Blinded, Placebo Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of MEDI6570 in Participants With a Prior Myocardial Infarction and Persistent Inflammation. U.S.National Institutes of Health.
39 ClinicalTrials.gov (NCT01609140) A Phase II Study of the Safety and Efficacy of MPSK3169A in Patients With Coronary Heart Disease or High Risk of Coronary Heart Disease. U.S. National Institutes of Health.
40 ClinicalTrials.gov (NCT00414869) Preliminary Efficacy and Tolerability of NCX-1000 After Repeated Oral Doses in Patients With Elevated Portal Pressure. U.S. National Institutes of Health.
41 ClinicalTrials.gov (NCT00240643) Use Of SB424323 With Aspirin In Non-Valvular Atrial Fibrillation In Patients At A Low Or Intermediate Risk For Stroke. U.S. National Institutes of Health.
42 ClinicalTrials.gov (NCT00924534) A Safety PK/PD Study of SLV337 in Patients With Type 2 Diabetes. U.S. National Institutes of Health.
43 ZK91587: a novel synthetic antimineralocorticoid displays high affinity for corticosterone (type I) receptors in the rat hippocampus. Life Sci. 1988;43(19):1537-43.
44 ClinicalTrials.gov (NCT00390767) Safety Study of MultiGeneAngio in Patients With Peripheral Arterial Disease (PAD). U.S. National Institutes of Health.
45 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800040974)
46 ClinicalTrials.gov (NCT02528526) Effects of OXY111A in Primary and Secondary Hepato-Pancreato-Biliary Neoplasm.
47 Pharmacokinetics and pharmacodynamics of a new cardiotonic vasodilator agent, 349U85, in normal subjects. Clin Pharmacol Ther. 1994 Jan;55(1):55-63.
48 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029409)
49 Clinical pipeline report, company report or official report of Cytori Therapeutics Inc.
50 ClinicalTrials.gov (NCT04588727) A Phase 1, Randomized, Single-blind, Placebo-controlled Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD3366 in Healthy Men and Women of Non-Childbearing Potential Following: Part A: Single Ascending Dose Administration (Including Populations of Japanese and Chinese Subjects) Part B: Single Dose Administration of AZD3366 at One Dose Level or Placebo With Concomitant Repeated Dosing of Ticagrelor and Acetylsalicylic Acid. U.S.National Institutes of Health.
51 ClinicalTrials.gov (NCT05512806) A Randomized, 6-period, 6-treatment, Single-Dose, Crossover Study to Assess the Pharmacokinetics of AZD5462 Film-coated Tablet Formulation, to Assess the Relative Bioavailability of AZD5462 Film-coated Tablet Formulation vs Oral Solution, and to Assess the Influence of Food on the Pharmacokinetics of AZD5462 in Healthy Participants. U.S.National Institutes of Health.
52 ClinicalTrials.gov (NCT01757860) Safety and Pharmacokinetics Study of CARD-024 in Healthy Subjects. U.S. National Institutes of Health.
53 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028119)
54 The cytokine milieu in the interplay of pathogenic Th1/Th17 cells and regulatory T cells in autoimmune disease. Cell Mol Immunol. 2010 May;7(3):182-9.
55 Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).
56 A phase I study of monohydroxyethylrutoside in healthy volunteers. Cancer Chemother Pharmacol. 2006 May;57(5):678-84.
57 Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors. Nat Rev Drug Discov. 2003 Jul;2(7):517-26.
58 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014336)
59 Cholesterol-lowering blockbuster candidates speed into Phase III trials. Nat Rev Drug Discov. 2012 Nov;11(11):817-9.
60 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032970)
61 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018454)
62 Renoprotective effects of combined endothelin-converting enzyme/neutral endopeptidase inhibitor SLV338 in acute and chronic experimental renal damage. Clin Lab. 2011;57(7-8):507-15.
63 ClinicalTrials.gov (NCT02034292) Safety Study of APD-791 With Aspirin and/or Clopidogrel. U.S. National Institutes of Health.
64 Clinical pipeline report, company report or official report of Exelixis (2011).
65 Discovery of cyclic sulfoxide hydroxyethylamines as potent and selective beta-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure based design and in vivo reduction of amyloid beta-peptides. Bioorg Med Chem Lett. 2013 Oct 1;23(19):5300-6.
66 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007387)
67 Clinical pipeline report, company report or official report of Karo Bio AB.
68 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004570)
69 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010238)
70 ClinicalTrials.gov (NCT00955747) Naturlose (D-Tagatose) Efficacy Evaluation Trial. U.S. National Institutes of Health.
71 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026047)
72 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004019)
73 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018915)
74 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013561)
75 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023346)
76 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009051)
77 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000283)
78 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014358)
79 Cholesterol-lowering blockbuster candidates speed into Phase III trials. Nat Rev Drug Discov. 2012 Nov;11(11):817-9.
80 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000367)
81 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026237)
82 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001304)
83 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033628)
84 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8584).
85 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005584)
86 Cardiovascular effects of the novel dual inhibitor of neutral endopeptidase and angiotensin-converting enzyme BMS-182657 in experimental hypertension and heart failure. J Pharmacol Exp Ther. 1995 Nov;275(2):745-52.
87 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027362)
88 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026848)
89 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005250)
90 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000134)
91 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001984)
92 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002104)
93 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001866)
94 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034860)
95 HDL mimetic peptide ATI-5261 forms an oligomeric assembly in solution that dissociates to monomers upon dilution. Biochemistry. 2011 May 17;50(19):4068-76.
96 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010420)
97 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028453)
98 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007258)
99 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007592)
100 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003366)
101 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1976).
102 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006851)
103 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
104 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 639).
105 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7041).
106 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 275).
107 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2340).
108 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 849).
109 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 328).
110 Clinical pipeline report, company report or official report of Merck.
111 Brothers in Arms: ABCA1- and ABCG1-Mediated Cholesterol Efflux as Promising Targets in Cardiovascular Disease Treatment.Pharmacol Rev. 2020 Jan;72(1):152-190. doi: 10.1124/pr.119.017897.
112 The apelinergic system: a perspective on challenges and opportunities in cardiovascular and metabolic disorders.Ann N Y Acad Sci. 2019 Nov;1455(1):12-33. doi: 10.1111/nyas.14123. Epub 2019 Jun 25.
113 2-Adrenoceptors and GRK2 as Potential Biomarkers in Patients With Chronic Pulmonary Regurgitation.Front Pharmacol. 2019 Feb 19;10:93. doi: 10.3389/fphar.2019.00093. eCollection 2019.
114 Genotype-phenotype associations in neovascular age-related macular degeneration.Retina. 2012 Oct;32(9):1950-8. doi: 10.1097/IAE.0b013e31824dadf1.
115 Relationship between circulating levels of angiotensin-converting enzyme 2-angiotensin-(1-7)-MAS axis and coronary heart disease.Heart Vessels. 2020 Feb;35(2):153-161. doi: 10.1007/s00380-019-01478-y. Epub 2019 Jul 29.
116 Statins and gastroduodenal endoscopic lesions: A case-control study.Medicine (Baltimore). 2018 Dec;97(50):e13579. doi: 10.1097/MD.0000000000013579.
117 Vascular Structure and Function in Cancer Survivors after Hematopoietic Stem Cell Transplantation.Biol Blood Marrow Transplant. 2019 Jan;25(1):151-156. doi: 10.1016/j.bbmt.2018.08.005. Epub 2018 Aug 10.
118 The impact of CCR5-32 deletion on C-reactive protein levels and cardiovascular disease: Results from the Danish Blood Donor Study.Atherosclerosis. 2015 Sep;242(1):222-5. doi: 10.1016/j.atherosclerosis.2015.07.031. Epub 2015 Jul 17.
119 Factor H C-Terminal Domains Are Critical for Regulation of Platelet/Granulocyte Aggregate Formation.Front Immunol. 2017 Nov 23;8:1586. doi: 10.3389/fimmu.2017.01586. eCollection 2017.
120 Acute phase serum cathepsin S level and cathepsin S/cystatin C ratio are the associated factors with cerebral infarction and their diagnostic value for cerebral infarction.Kaohsiung J Med Sci. 2019 Feb;35(2):95-101. doi: 10.1002/kjm2.12014.
121 Long term adjuvant endocrine therapy and risk of cardiovascular disease in female breast cancer survivors: systematic review.BMJ. 2018 Oct 8;363:k3845. doi: 10.1136/bmj.k3845.
122 Genetic and Pharmacologic Inhibition of the Neutrophil Elastase Inhibits Experimental Atherosclerosis.J Am Heart Assoc. 2018 Feb 8;7(4):e008187. doi: 10.1161/JAHA.117.008187.
123 Soluble endoglin and hypercholesterolemia aggravate endothelial and vessel wall dysfunction in mouse aorta.Atherosclerosis. 2018 Apr;271:15-25. doi: 10.1016/j.atherosclerosis.2018.02.008. Epub 2018 Feb 9.
124 Serum fatty acid binding proteins as a potential biomarker in atrial fibrillation.J Physiol Pharmacol. 2019 Feb;70(1). doi: 10.26402/jpp.2019.1.11. Epub 2019 Jun 3.
125 Glucose-6-phosphate dehydrogenase deficiency and risk of cardiovascular disease: A propensity score-matched study.Atherosclerosis. 2019 Mar;282:148-153. doi: 10.1016/j.atherosclerosis.2019.01.027. Epub 2019 Jan 28.
126 Glucose-dependent insulinotropic polypeptide (GIP) and cardiovascular disease.Peptides. 2020 Mar;125:170174. doi: 10.1016/j.peptides.2019.170174. Epub 2019 Nov 2.
127 G Protein-Coupled Receptor Kinase 2 (GRK2) as a Potential Therapeutic Target in Cardiovascular and Metabolic Diseases.Front Pharmacol. 2019 Feb 19;10:112. doi: 10.3389/fphar.2019.00112. eCollection 2019.
128 A Phase IV, Randomized, Double-Blind, Placebo-Controlled Crossover Study of the Effects of Ustekinumab on Vascular Inflammation in Psoriasis (the VIP-U Trial).J Invest Dermatol. 2020 Jan;140(1):85-93.e2. doi: 10.1016/j.jid.2019.07.679. Epub 2019 Jul 19.
129 KDM3A inhibition modulates macrophage polarization to aggravate post-MI injuries and accelerates adverse ventricular remodeling via an IRF4 signaling pathway.Cell Signal. 2019 Dec;64:109415. doi: 10.1016/j.cellsig.2019.109415. Epub 2019 Sep 9.
130 Prostate-Specific Antigen Within the Reference Range, Subclinical Coronary Atherosclerosis, and Cardiovascular Mortality.Circ Res. 2019 May 10;124(10):1492-1504. doi: 10.1161/CIRCRESAHA.118.313413.
131 Leptin Receptor Gene Polymorphism and the Risk of Cardiovascular Disease: A Systemic Review and Meta-Analysis.Int J Environ Res Public Health. 2017 Apr 3;14(4):375. doi: 10.3390/ijerph14040375.
132 Benzothiazole-based compounds as potent endothelial lipase inhibitors.Bioorg Med Chem Lett. 2019 Oct 15;29(20):126673. doi: 10.1016/j.bmcl.2019.126673. Epub 2019 Sep 6.
133 Map4k4 Signaling Nodes in Metabolic and Cardiovascular Diseases.Trends Endocrinol Metab. 2016 Jul;27(7):484-492. doi: 10.1016/j.tem.2016.04.006. Epub 2016 May 6.
134 Systemic medications and cortical cataract: the Singapore Epidemiology of Eye Diseases Study.Br J Ophthalmol. 2020 Mar;104(3):330-335. doi: 10.1136/bjophthalmol-2019-314256. Epub 2019 Jul 4.
135 The circulating form of neprilysin is not a general biomarker for overall survival in treatment-nave cancer patients.Sci Rep. 2019 Feb 22;9(1):2554. doi: 10.1038/s41598-019-38867-2.
136 Cardiovascular disease in systemic lupus erythematosus is associated with increased levels of biomarkers reflecting receptor-activated apoptosis.Atherosclerosis. 2018 Mar;270:1-7. doi: 10.1016/j.atherosclerosis.2018.01.022. Epub 2018 Jan 17.
137 Design and Synthesis of Ionic Liquid-Based Matrix Metalloproteinase Inhibitors (MMPIs): A Simple Approach to Increase Hydrophilicity and to Develop MMPI-Coated Gold Nanoparticles.ChemMedChem. 2019 Mar 22;14(6):686-698. doi: 10.1002/cmdc.201800733. Epub 2019 Feb 14.
138 Matrix metalloproteinase-8 and tissue inhibitor of matrix metalloproteinase-1 predict incident cardiovascular disease events and all-cause mortality in a population-based cohort.Eur J Prev Cardiol. 2017 Jul;24(11):1136-1144. doi: 10.1177/2047487317706585. Epub 2017 Apr 21.
139 The crystal structure of human microsomal triglyceride transfer protein.Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17251-17260. doi: 10.1073/pnas.1903029116. Epub 2019 Aug 8.
140 Biophysical screening methods for extracellular domain peptide receptors, application to natriuretic peptide receptor C ligands.Chem Biol Drug Des. 2019 Jun;93(6):1011-1020. doi: 10.1111/cbdd.13395. Epub 2018 Oct 10.
141 Two Birds with One Stone: Regular Use of PDE5 Inhibitors for Treating Male Patients with Erectile Dysfunction and Cardiovascular Diseases.Cardiovasc Drugs Ther. 2019 Feb;33(1):119-128. doi: 10.1007/s10557-019-06851-7.
142 Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes.Circ Res. 2020 Jan 31;126(3):330-346. doi: 10.1161/CIRCRESAHA.119.315246. Epub 2019 Nov 19.
143 Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.J Am Coll Cardiol. 2013 Nov 19;62(21):1966-1976. doi: 10.1016/j.jacc.2013.06.044. Epub 2013 Jul 31.
144 Platelet surface expression of cyclophilin A is associated with increased mortality in patients with symptomatic coronary artery disease.J Thromb Haemost. 2020 Jan;18(1):234-242. doi: 10.1111/jth.14635. Epub 2019 Oct 20.
145 The Role of Protein Tyrosine Phosphatase (PTP)-1B in Cardiovascular Disease and Its Interplay with Insulin Resistance.Biomolecules. 2019 Jul 17;9(7):286. doi: 10.3390/biom9070286.
146 S100A8/A9 in Myocardial Infarction.Methods Mol Biol. 2019;1929:739-754. doi: 10.1007/978-1-4939-9030-6_46.
147 Rare P376L variant in the SR-BI gene associates with HDL dysfunction and risk of cardiovascular disease.Clin Biochem. 2019 Nov;73:44-49. doi: 10.1016/j.clinbiochem.2019.06.014. Epub 2019 Jun 25.
148 Variant frequencies of KCNQ1, KCNH2, and SCN5A in a Chinese inherited arrhythmia cohort and other disease cohorts undergoing genetic testing.Ann Hum Genet. 2020 Mar;84(2):161-168. doi: 10.1111/ahg.12359. Epub 2019 Nov 7.
149 BARI 2D: A Reanalysis Focusing on Cardiovascular Events.Mayo Clin Proc. 2019 Nov;94(11):2249-2262. doi: 10.1016/j.mayocp.2019.04.015. Epub 2019 Oct 4.
150 Phytochemical, Anti-diabetic and Cardiovascular Properties of Urtica dioica L. (Urticaceae): A Review.Mini Rev Med Chem. 2019;19(1):63-71. doi: 10.2174/1389557518666180924121528.
151 Association between AT C573T polymorphism and cardiovascular risk factors in myocardial infarction.Cardiovasc Pathol. 2011 May-Jun;20(3):156-61. doi: 10.1016/j.carpath.2010.04.002. Epub 2010 Jun 7.
152 A polymorphism in the norepinephrine transporter gene is associated with affective and cardiovascular disease through a microRNA mechanism.Mol Psychiatry. 2017 Jan;22(1):134-141. doi: 10.1038/mp.2016.40. Epub 2016 Apr 5.
153 Impact of genetic variation in the 5-HT transporter and receptor on platelet function in patients with stable CAD taking aspirin.Thromb Res. 2016 Oct;146:51-55. doi: 10.1016/j.thromres.2016.08.019. Epub 2016 Aug 20.
154 Association between vitamin D deficiency and lipid and non-lipid markers of cardiovascular diseases in the middle east region.Eur J Clin Nutr. 2019 Jun;73(6):850-858. doi: 10.1038/s41430-018-0280-1. Epub 2018 Aug 10.
155 Thrombomodulin in disseminated intravascular coagulation and other critical conditions-a multi-faceted anticoagulant protein with therapeutic potential.Crit Care. 2019 Aug 15;23(1):280. doi: 10.1186/s13054-019-2552-0.
156 Thrombospondin 1 Is Increased in the Aorta and Plasma of Patients With Acute Aortic Dissection.Can J Cardiol. 2019 Jan;35(1):42-50. doi: 10.1016/j.cjca.2018.11.008. Epub 2018 Nov 22.
157 The effects of fatty acids consumption on OPG/RANKL/RANK system in cardiovascular diseases: Current status and future perspectives for the impact of diet-gene interaction.J Cell Biochem. 2019 Mar;120(3):2774-2781. doi: 10.1002/jcb.27672. Epub 2018 Sep 30.
158 TSPO ligands prevent the proliferation of vascular smooth muscle cells and attenuate neointima formation through AMPK activation.Acta Pharmacol Sin. 2020 Jan;41(1):34-46. doi: 10.1038/s41401-019-0293-x. Epub 2019 Sep 12.
159 Cardiovascular protective effect of pioglitazone on oxidative stress in rats with metabolic syndrome.J Chin Med Assoc. 2019 Jun;82(6):452-456. doi: 10.1097/JCMA.0000000000000103.
160 Uncoupling Protein 2 in Cardiovascular Health and Disease.Front Physiol. 2018 Aug 2;9:1060. doi: 10.3389/fphys.2018.01060. eCollection 2018.
161 Missense mutation of VKORC1 leads to medial arterial calcification in rats.Sci Rep. 2018 Sep 13;8(1):13733. doi: 10.1038/s41598-018-31788-6.
162 The ABCG5 ABCG8 sterol transporter and phytosterols: implications for cardiometabolic disease.Curr Opin Endocrinol Diabetes Obes. 2009 Apr;16(2):172-7. doi: 10.1097/med.0b013e3283292312.
163 Atypical Chemokine Receptors in Cardiovascular Disease.Thromb Haemost. 2019 Apr;119(4):534-541. doi: 10.1055/s-0038-1676988. Epub 2019 Feb 4.
164 Elevated expression of the metalloproteinase ADAM8 associates with vascular diseases in mice and humans.Atherosclerosis. 2019 Jul;286:163-171. doi: 10.1016/j.atherosclerosis.2019.03.008. Epub 2019 Mar 17.
165 ADAMTS5 deficiency in mice does not affect cardiac function.Cell Biol Int. 2019 Jun;43(6):593-604. doi: 10.1002/cbin.11130. Epub 2019 Apr 21.
166 Endogenous intermedin protects against intimal hyperplasia by inhibiting endoplasmic reticulum stress.Peptides. 2019 Nov;121:170131. doi: 10.1016/j.peptides.2019.170131. Epub 2019 Aug 10.
167 Plasma glycomics predict cardiovascular disease in patients with ART-controlled HIV infections.FASEB J. 2019 Feb;33(2):1852-1859. doi: 10.1096/fj.201800923R. Epub 2018 Sep 5.
168 Genetics of diabetes complications.Mamm Genome. 2014 Oct;25(9-10):384-400. doi: 10.1007/s00335-014-9543-x. Epub 2014 Aug 29.
169 Discovery and Validation of a Novel Neutrophil Activation Marker Associated with Obesity.Sci Rep. 2019 Mar 5;9(1):3433. doi: 10.1038/s41598-019-39764-4.
170 Apolipoprotein A-IV: A potential therapeutic target for atherosclerosis.Prostaglandins Other Lipid Mediat. 2018 Nov;139:87-92. doi: 10.1016/j.prostaglandins.2018.10.004. Epub 2018 Oct 22.
171 Connective Tissue Growth Factor Is Related to All-cause Mortality in Hemodialysis Patients and Is Lowered by On-line Hemodiafiltration: Results from the Convective Transport Study.Toxins (Basel). 2019 May 13;11(5):268. doi: 10.3390/toxins11050268.
172 Blood Pressure and Development of Cardiovascular Disease in Koreans With Type 2 Diabetes Mellitus.Hypertension. 2019 Feb;73(2):319-326.
173 B- and T-lymphocyte attenuator stimulation protects against atherosclerosis by regulating follicular B cells.Cardiovasc Res. 2020 Feb 1;116(2):295-305. doi: 10.1093/cvr/cvz129.
174 Elevated serum uric acid predicts the development of moderate coronary artery calcification independent of conventional cardiovascular risk factors.Atherosclerosis. 2018 May;272:233-239. doi: 10.1016/j.atherosclerosis.2018.02.014. Epub 2018 Feb 14.
175 Verapamil decreases calpain-1 and matrix metalloproteinase-2 activities and improves hypertension-induced hypertrophic cardiac remodeling in rats.Life Sci. 2020 Mar 1;244:117153. doi: 10.1016/j.lfs.2019.117153. Epub 2019 Dec 10.
176 Interleukin-6 is an independent predictor of progressive atherosclerosis in the carotid artery: The Troms Study.Atherosclerosis. 2018 Apr;271:1-8. doi: 10.1016/j.atherosclerosis.2018.02.005. Epub 2018 Feb 7.
177 Systemic Inflammation in Metabolic Syndrome: Increased Platelet and Leukocyte Activation, and Key Role of CX(3)CL1/CX(3)CR1 and CCL2/CCR2 Axes in Arterial Platelet-Proinflammatory Monocyte Adhesion.J Clin Med. 2019 May 18;8(5):708. doi: 10.3390/jcm8050708.
178 Genetic variations in the thrombin-activatable fibrinolysis inhibitor gene and risk of cardiovascular disease: a systematic review and meta-analysis.Thromb Res. 2014 Sep;134(3):610-6. doi: 10.1016/j.thromres.2014.06.023. Epub 2014 Jul 5.
179 Mechanism of H(2)S-mediated ROCK inhibition of total flavones of Rhododendra against myocardial ischemia injury.Exp Ther Med. 2019 Nov;18(5):3783-3792. doi: 10.3892/etm.2019.8004. Epub 2019 Sep 13.
180 Cathepsin K knockout protects against cardiac dysfunction in diabetic mice.Sci Rep. 2017 Aug 18;7(1):8703. doi: 10.1038/s41598-017-09037-z.
181 Maternal diabetes up-regulates NOX2 and enhances myocardial ischaemia/reperfusion injury in adult offspring.J Cell Mol Med. 2018 Apr;22(4):2200-2209. doi: 10.1111/jcmm.13500. Epub 2018 Jan 29.
182 Regulation of CYP2J2 and EET Levels in Cardiac Disease and Diabetes.Int J Mol Sci. 2018 Jun 29;19(7):1916. doi: 10.3390/ijms19071916.
183 DUSP1 Is a Potential Marker of Chronic Inflammation in Arabs with Cardiovascular Diseases.Dis Markers. 2018 Dec 13;2018:9529621. doi: 10.1155/2018/9529621. eCollection 2018.
184 3D MicroCT spatial and temporal characterization of thoracic aorta perivascular adipose tissue and plaque volumes in the ApoE-/- mouse model.Adipocyte. 2018;7(3):156-165. doi: 10.1080/21623945.2018.1493900. Epub 2018 Aug 9.
185 Filaggrin variations are associated with PAH metabolites in urine and DNA alterations in blood.Environ Res. 2019 Oct;177:108600. doi: 10.1016/j.envres.2019.108600. Epub 2019 Jul 22.
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367 Effect of Bariatric Weight Loss on the Adipose Lipolytic Transcriptome in Obese Humans.Mediators Inflamm. 2015;2015:106237. doi: 10.1155/2015/106237. Epub 2015 Nov 18.
368 Association of Triglyceride-Lowering LPL Variants and LDL-C-Lowering LDLR Variants With Risk of Coronary Heart Disease.JAMA. 2019 Jan 29;321(4):364-373. doi: 10.1001/jama.2018.20045.
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377 Inhibition of Vascular c-Jun N-Terminal Kinase 2 Improves Obesity-Induced Endothelial Dysfunction After Roux-en-Y Gastric Bypass.J Am Heart Assoc. 2017 Nov 14;6(11):e006441. doi: 10.1161/JAHA.117.006441.
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392 Neuropeptide Y predicts cardiovascular events in chronic kidney disease patients: a cohort study.J Hypertens. 2019 Jul;37(7):1359-1365. doi: 10.1097/HJH.0000000000002030.
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472 Structure of the human TRPM4 ion channel in a lipid nanodisc.Science. 2018 Jan 12;359(6372):228-232. doi: 10.1126/science.aar4510. Epub 2017 Dec 7.
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477 Thermoneutrality but Not UCP1 Deficiency Suppresses Monocyte Mobilization Into Blood.Circ Res. 2017 Sep 1;121(6):662-676. doi: 10.1161/CIRCRESAHA.117.311519. Epub 2017 Jul 10.
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485 Urinary Biomarkers of Kidney Tubular Damage and Risk of Cardiovascular Disease and Mortality in Elders.Am J Kidney Dis. 2018 Aug;72(2):205-213. doi: 10.1053/j.ajkd.2017.12.013. Epub 2018 Mar 27.
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487 GLUT2, glucose sensing and glucose homeostasis.Diabetologia. 2015 Feb;58(2):221-32. doi: 10.1007/s00125-014-3451-1. Epub 2014 Nov 25.
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491 Influence of coronary artery disease and subclinical atherosclerosis related polymorphisms on the risk of atherosclerosis in rheumatoid arthritis.Sci Rep. 2017 Jan 6;7:40303. doi: 10.1038/srep40303.
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493 Performance on management strategies with Class I Recommendation and A Level of Evidence among hospitalized patients with non-ST-segment elevation acute coronary syndrome in China: Findings from the Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome (CCC-ACS) project.Am Heart J. 2019 Jun;212:80-90. doi: 10.1016/j.ahj.2019.02.012. Epub 2019 Mar 4.
494 Advances in understanding the regulatory mechanism of cholesterol 7-hydroxylase.Biochem Pharmacol. 2019 Jun;164:152-164. doi: 10.1016/j.bcp.2019.04.008. Epub 2019 Apr 10.
495 Hepatic overexpression of methionine sulfoxide reductase A reduces atherosclerosis in apolipoprotein E-deficient mice.J Lipid Res. 2015 Oct;56(10):1891-900. doi: 10.1194/jlr.M058776. Epub 2015 Aug 28.
496 Alcohol consumption, genetic variants in alcohol deydrogenases, and risk of cardiovascular diseases: a prospective study and meta-analysis.PLoS One. 2012;7(2):e32176. doi: 10.1371/journal.pone.0032176. Epub 2012 Feb 21.
497 Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.Am J Hum Genet. 2008 Jan;82(1):139-49. doi: 10.1016/j.ajhg.2007.11.001.
498 Antiglycation, radical scavenging, and semicarbazide-sensitive amine oxidase inhibitory activities of acetohydroxamic acid in vitro.Drug Des Devel Ther. 2017 Jul 13;11:2139-2147. doi: 10.2147/DDDT.S141740. eCollection 2017.
499 Low-level arsenic exposure, AS3MT gene polymorphism and cardiovascular diseases in rural Texas counties.Environ Res. 2012 Feb;113:52-7. doi: 10.1016/j.envres.2012.01.003. Epub 2012 Feb 15.
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501 Sterol 27-Hydroxylase Polymorphism Significantly Associates With Shorter Telomere, Higher Cardiovascular and Type-2 Diabetes Risk in Obese Subjects.Front Endocrinol (Lausanne). 2018 Jun 13;9:309. doi: 10.3389/fendo.2018.00309. eCollection 2018.
502 Association of 1347 G/A cytochrome P450 4F2 (CYP4F2) gene variant with hypertension and stroke.Mol Biol Rep. 2012 Feb;39(2):1677-82. doi: 10.1007/s11033-011-0907-y. Epub 2011 May 31.
503 Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine.Circ Cardiovasc Genet. 2014 Dec;7(6):864-72. doi: 10.1161/CIRCGENETICS.113.000264. Epub 2014 Sep 21.
504 Effect of polymorphisms in the NADSYN1/DHCR7 locus (rs12785878 and rs1790349) on plasma 25-hydroxyvitamin D levels and coronary artery disease incidence.J Nutrigenet Nutrigenomics. 2013;6(6):327-35. doi: 10.1159/000360422. Epub 2014 Mar 15.
505 Characterization of fatty acid amide hydrolase activity by a fluorescence-based assay.Anal Biochem. 2018 Apr 1;546:50-57. doi: 10.1016/j.ab.2018.01.026. Epub 2018 Jan 31.
506 Genetic variation in FADS1 has little effect on the association between dietary PUFA intake and cardiovascular disease.J Nutr. 2014 Sep;144(9):1356-63. doi: 10.3945/jn.114.192708. Epub 2014 Jul 9.
507 Flavin-containing monooxygenase 3 (FMO3): genetic variants and their consequences for drug metabolism and disease.Xenobiotica. 2020 Jan;50(1):19-33. doi: 10.1080/00498254.2019.1643515. Epub 2019 Aug 1.
508 Obesity genotype score and cardiovascular risk in women with type 2 diabetes mellitus.Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):327-32. doi: 10.1161/ATVBAHA.109.196196. Epub 2009 Nov 12.
509 MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate.Am J Clin Nutr. 2010 May;91(5):1377-86. doi: 10.3945/ajcn.2009.28923. Epub 2010 Mar 24.
510 Association of MT1A haplotype with cardiovascular disease and antioxidant enzyme defense in elderly Greek population: comparison with an Italian cohort.J Nutr Biochem. 2010 Oct;21(10):1008-14. doi: 10.1016/j.jnutbio.2009.08.008. Epub 2009 Dec 4.
511 Pharmacodynamic effects of Dan-hong injection in rats with blood stasis syndrome.Biomed Pharmacother. 2019 Oct;118:109187. doi: 10.1016/j.biopha.2019.109187. Epub 2019 Jul 11.
512 Physiological Study on Association between Nicotinamide N-Methyltransferase Gene Polymorphisms and Hyperlipidemia.Biomed Res Int. 2016;2016:7521942. doi: 10.1155/2016/7521942. Epub 2016 Nov 23.
513 Analysis of mRNA from human heart tissue and putative applications in forensic molecular pathology.Forensic Sci Int. 2010 Dec 15;203(1-3):99-105. doi: 10.1016/j.forsciint.2010.07.005. Epub 2010 Aug 12.
514 Paraoxonase 3: Structure and Its Role in Pathophysiology of Coronary Artery Disease.Biomolecules. 2019 Dec 3;9(12):817. doi: 10.3390/biom9120817.
515 Phenol-enriched olive oils modify paraoxonase-related variables: A randomized, crossover, controlled trial.Mol Nutr Food Res. 2017 Oct;61(10). doi: 10.1002/mnfr.201600932. Epub 2017 Jul 20.
516 Implication of osteoprotegerin and sclerostin in axial spondyloarthritis cardiovascular disease: study of 163 Spanish patients.Clin Exp Rheumatol. 2018 Mar-Apr;36(2):302-309. Epub 2017 Dec 15.
517 Genetic polymorphisms in platelet-related proteins and coronary artery disease: investigation of candidate genes, including N-acetylgalactosaminyltransferase 4 (GALNT4) and sulphotransferase 1A1/2 (SULT1A1/2).J Thromb Thrombolysis. 2009 Feb;27(2):175-84. doi: 10.1007/s11239-008-0196-z. Epub 2008 Feb 8.
518 Assessment of left atrial function using speckle tracking echocardiography in ankylosing spondylitis: a case-control study.Int J Cardiovasc Imaging. 2018 Dec;34(12):1863-1868. doi: 10.1007/s10554-018-1411-4. Epub 2018 Jul 16.
519 The Implication of the Polymorphisms of COX-1, UGT1A6, and CYP2C9 among Cardiovascular Disease (CVD) Patients Treated with Aspirin.J Pharm Pharm Sci. 2015;18(3):474-83. doi: 10.18433/j3fc7f.
520 Reduction of plasma angiopoietin-like 2 after cardiac surgery is related to tissue inflammation and senescence status of patients.J Thorac Cardiovasc Surg. 2019 Sep;158(3):792-802.e5. doi: 10.1016/j.jtcvs.2018.12.047. Epub 2019 Jan 8.
521 (Pro)renin Receptor Blockade Ameliorates Heart Failure Caused by Chronic Kidney Disease.J Card Fail. 2019 Apr;25(4):286-300. doi: 10.1016/j.cardfail.2019.02.009. Epub 2019 Feb 13.
522 The Role of RP105 in Cardiovascular Disease through Regulating TLR4 and PI3K Signaling Pathways.Curr Med Sci. 2019 Apr;39(2):185-189. doi: 10.1007/s11596-019-2017-3. Epub 2019 Apr 23.
523 Activity of Antioxidant Enzymes and Their Association with Lipid Profile in Mexican People without Cardiovascular Disease: An Analysis of Interactions.Int J Environ Res Public Health. 2018 Nov 28;15(12):2687. doi: 10.3390/ijerph15122687.
524 Cost-effectiveness and budget impact of the community-based management of hypertension in Nepal study (COBIN): a retrospective analysis.Lancet Glob Health. 2019 Oct;7(10):e1367-e1374. doi: 10.1016/S2214-109X(19)30338-9.
525 ETV2/ER71 Transcription Factor as a Therapeutic Vehicle for Cardiovascular Disease.Theranostics. 2019 Aug 9;9(19):5694-5705. doi: 10.7150/thno.35300. eCollection 2019.
526 FAM3B mediates high glucose-induced vascular smooth muscle cell proliferation and migration via inhibition of miR-322-5p.Sci Rep. 2017 May 23;7(1):2298. doi: 10.1038/s41598-017-02683-3.
527 MicroRNA?4a mediates atrial fibrillation through regulation of AnkyrinB expression.Mol Med Rep. 2018 Jun;17(6):8457-8465. doi: 10.3892/mmr.2018.8873. Epub 2018 Apr 12.
528 High circulating follistatin-like protein 1 as a biomarker of a metabolically unhealthy state.Endocr J. 2019 Mar 28;66(3):241-251. doi: 10.1507/endocrj.EJ18-0352. Epub 2019 Feb 8.
529 Association of the G-protein 3 subunit gene polymorphism with the incidence of cardiovascular disease independent of hypertension: the Funagata study.J Hum Hypertens. 2013 Oct;27(10):612-6. doi: 10.1038/jhh.2013.28. Epub 2013 Apr 18.
530 Blood kidney injury molecule-1 predicts short and longer term kidney outcomes in patients undergoing diagnostic coronary and/or peripheral angiography-Results from the Catheter Sampled Blood Archive in Cardiovascular Diseases (CASABLANCA) study.Am Heart J. 2019 Mar;209:36-46. doi: 10.1016/j.ahj.2018.12.001. Epub 2018 Dec 7.
531 A polymorphism of the interferon-gamma-inducible protein 30 gene is associated with hyperglycemia in severely obese individuals.Hum Genet. 2012 Jan;131(1):57-66. doi: 10.1007/s00439-011-1043-4. Epub 2011 Jun 24.
532 Cost-Effectiveness of the US Food and Drug Administration Added Sugar Labeling Policy for Improving Diet and Health.Circulation. 2019 Jun 4;139(23):2613-2624. doi: 10.1161/CIRCULATIONAHA.118.036751. Epub 2019 Apr 15.
533 KIF6 gene as a pharmacogenetic marker for lipid-lowering effect in statin treatment.PLoS One. 2018 Oct 10;13(10):e0205430. doi: 10.1371/journal.pone.0205430. eCollection 2018.
534 Multiple roles of KLF15 in the heart: Underlying mechanisms and therapeutic implications.J Mol Cell Cardiol. 2019 Apr;129:193-196. doi: 10.1016/j.yjmcc.2019.01.024. Epub 2019 Mar 2.
535 PEGylated gold nanorods are not cytotoxic to human endothelial cells but affect kruppel-like factor signaling pathway.Toxicol Appl Pharmacol. 2019 Nov 1;382:114758. doi: 10.1016/j.taap.2019.114758. Epub 2019 Sep 12.
536 Association between systemic leptin and neurotensin concentration in adult individuals with and without type 2 diabetes mellitus.J Endocrinol Invest. 2018 Oct;41(10):1159-1163. doi: 10.1007/s40618-018-0845-9. Epub 2018 Feb 7.
537 Augmented PLA2 activity in pre-eclamptic decidual tissue--a key player in the pathophysiology of 'acute atherosis' in pre-eclampsia?.Placenta. 2003 Nov;24(10):965-73. doi: 10.1016/s0143-4004(03)00175-9.
538 Impact of a variable number tandem repeat in the CYP2C9 promoter on warfarin sensitivity and responsiveness in Jordanians with cardiovascular disease.Pharmgenomics Pers Med. 2019 Mar 21;12:15-22. doi: 10.2147/PGPM.S189838. eCollection 2019.
539 The clinical impact of growth differentiation factor-15 in heart disease: A 2019 update.Crit Rev Clin Lab Sci. 2020 Mar;57(2):114-125. doi: 10.1080/10408363.2019.1678565. Epub 2019 Oct 30.
540 Ca(2+)-Binding Proteins of the EF-Hand Superfamily: Diagnostic and Prognostic Biomarkers and Novel Therapeutic Targets.Methods Mol Biol. 2019;1929:157-186. doi: 10.1007/978-1-4939-9030-6_11.
541 Effect of single nucleotide polymorphisms in SEPS1 and SEPP1 on expression in the protein level in metabolic syndrome in subjects with cardiovascular disease.Mol Biol Rep. 2019 Dec;46(6):5685-5693. doi: 10.1007/s11033-019-05000-5. Epub 2019 Sep 21.
542 High-throughput targeted proteomics discovery approach and spontaneous reperfusion in ST-segment elevation myocardial infarction.Am Heart J. 2020 Feb;220:137-144. doi: 10.1016/j.ahj.2019.09.015. Epub 2019 Nov 9.
543 Spexin protects cardiomyocytes from hypoxia-induced metabolic and mitochondrial dysfunction.Naunyn Schmiedebergs Arch Pharmacol. 2020 Jan;393(1):25-33. doi: 10.1007/s00210-019-01708-0. Epub 2019 Aug 8.
544 Antihypertensive therapy, the alpha-adducin polymorphism, and cardiovascular disease in high-risk hypertensive persons: the Genetics of Hypertension-Associated Treatment Study.Pharmacogenomics J. 2007 Apr;7(2):112-22. doi: 10.1038/sj.tpj.6500395. Epub 2006 May 16.
545 In silico analysis of nonsynonymous single nucleotide polymorphisms of the human adiponectin receptor 2 (ADIPOR2) gene.Comput Biol Chem. 2017 Jun;68:175-185. doi: 10.1016/j.compbiolchem.2017.03.005. Epub 2017 Mar 14.
546 A-kinase anchoring protein 1 (AKAP1) and its role in some cardiovascular diseases.J Mol Cell Cardiol. 2020 Jan;138:99-109. doi: 10.1016/j.yjmcc.2019.11.154. Epub 2019 Nov 26.
547 Effects of AMPD1 gene C34T polymorphism on cardiac index, blood pressure and prognosis in patients with cardiovascular diseases: a meta-analysis.BMC Cardiovasc Disord. 2017 Jul 3;17(1):174. doi: 10.1186/s12872-017-0608-0.
548 Effects of angiotensin III on c-Jun N terminal kinase in Wistar and hypertensive rat vascular smooth muscle cells.Peptides. 2020 Jan;123:170204. doi: 10.1016/j.peptides.2019.170204. Epub 2019 Nov 15.
549 The potential role of angiopoietin-like protein-8 in type 2 diabetes mellitus: a possibility for predictive diagnosis and targeted preventive measures?.EPMA J. 2019 Aug 6;10(3):239-248. doi: 10.1007/s13167-019-00180-3. eCollection 2019 Sep.
550 The emerging role of sorting nexins in cardiovascular diseases.Clin Sci (Lond). 2019 Mar 15;133(5):723-737. doi: 10.1042/CS20190034. Print 2019 Mar 29.
551 Detection of Left Ventricular Hypertrophy Using Bayesian Additive Regression Trees: The MESA.J Am Heart Assoc. 2019 Mar 5;8(5):e009959. doi: 10.1161/JAHA.118.009959.
552 A familial congenital heart disease with a possible multigenic origin involving a mutation in BMPR1A.Sci Rep. 2019 Feb 27;9(1):2959. doi: 10.1038/s41598-019-39648-7.
553 Single systemic transfer of a human gene associated with exceptional longevity halts the progression of atherosclerosis and inflammation in ApoE knockout mice through a CXCR4-mediated mechanism.Eur Heart J. 2020 Jul 7;41(26):2487-2497. doi: 10.1093/eurheartj/ehz459.
554 C1qTNF-related protein-6 protects against doxorubicin-induced cardiac injury.J Cell Biochem. 2019 Jun;120(6):10748-10755. doi: 10.1002/jcb.28366. Epub 2019 Feb 5.
555 C1q tumor necrosis factor-related protein 9 in atherosclerosis: Mechanistic insights and therapeutic potential.Atherosclerosis. 2018 Sep;276:109-116. doi: 10.1016/j.atherosclerosis.2018.07.022. Epub 2018 Jul 19.
556 All-cause and cause-specific mortality in individuals with zero and minimal coronary artery calcium: A long-term, competing risk analysis in the Coronary Artery Calcium Consortium.Atherosclerosis. 2020 Feb;294:72-79. doi: 10.1016/j.atherosclerosis.2019.11.008. Epub 2019 Nov 16.
557 S100 proteins: Diagnostic and prognostic biomarkers in laboratory medicine.Biochim Biophys Acta Mol Cell Res. 2019 Jul;1866(7):1197-1206. doi: 10.1016/j.bbamcr.2018.10.015. Epub 2018 Oct 28.
558 Association of Calpain (CAPN) 10 (UCSNP-43, rs3792267) gene polymorphism with elevated serum androgens in young women with the most severe phenotype of polycystic ovary syndrome (PCOS).Gynecol Endocrinol. 2015;31(8):630-4. doi: 10.3109/09513590.2015.1032932. Epub 2015 Sep 17.
559 MDR reversal and pro-apoptotic effects of statins and statins combined with flavonoids in colon cancer cells.Biomed Pharmacother. 2019 Jan;109:1511-1522. doi: 10.1016/j.biopha.2018.10.169. Epub 2018 Nov 14.
560 A role for collagen type IV in cardiovascular disease?.Am J Physiol Heart Circ Physiol. 2018 Sep 1;315(3):H610-H625. doi: 10.1152/ajpheart.00070.2018. Epub 2018 Apr 20.
561 Thrombophilia in 153 Patients With Premature Cardiovascular Disease Age 45.Clin Appl Thromb Hemost. 2018 Mar;24(2):295-302. doi: 10.1177/1076029617703481. Epub 2017 Apr 12.
562 Creg in Hepatocytes Ameliorates Liver Ischemia/Reperfusion Injury in a TAK1-Dependent Manner in Mice.Hepatology. 2019 Jan;69(1):294-313. doi: 10.1002/hep.30203.
563 Human Leukocyte Antigen Shared Epitope and Inflammation, Cardiovascular Disease, Cancer, and Mortality Among Postmenopausal Women in the Women's Health Initiative Rheumatoid Arthritis Study.Am J Epidemiol. 2017 Jul 15;186(2):245-254. doi: 10.1093/aje/kwx087.
564 Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors.Psychol Med. 2019 Jul;49(10):1749-1757. doi: 10.1017/S0033291718004142. Epub 2019 Jan 28.
565 Risk of cerebro- and cardiovascular disease in patients with scrub typhus.Eur J Clin Microbiol Infect Dis. 2020 Mar;39(3):451-454. doi: 10.1007/s10096-019-03743-4. Epub 2019 Nov 27.
566 Genetic and environmental determinants of dimethylarginines and association with cardiovascular disease in patients with type 2 diabetes.Diabetes Care. 2014;37(3):846-54. doi: 10.2337/dc13-0546. Epub 2013 Nov 1.
567 Pharmacologic epigenetic modulators of alkaline phosphatase in chronic kidney disease.Curr Opin Nephrol Hypertens. 2020 Jan;29(1):4-15. doi: 10.1097/MNH.0000000000000570.
568 Hodgkin lymphoma of the elderly patients: a retrospective multicenter analysis from the Polish Lymphoma Research Group().Leuk Lymphoma. 2019 Feb;60(2):341-348. doi: 10.1080/10428194.2018.1482539. Epub 2018 Jul 6.
569 Correction: PARS risk charts: A 10-year study of risk assessment for cardiovascular diseases in Eastern Mediterranean Region.PLoS One. 2018 Jan 25;13(1):e0191379. doi: 10.1371/journal.pone.0191379. eCollection 2018.
570 MiR-92a contributes to the cardiovascular disease development in diabetes mellitus through NF-B and downstream inflammatory pathways.Eur Rev Med Pharmacol Sci. 2019 Apr;23(7):3070-3079. doi: 10.26355/eurrev_201904_17589.
571 The role of FHL2 in wound healing and inflammation.FASEB J. 2019 Jul;33(7):7799-7809. doi: 10.1096/fj.201802765RR. Epub 2019 Apr 2.
572 FNDC5: A novel player in metabolism and metabolic syndrome.Biochimie. 2019 Mar;158:111-116. doi: 10.1016/j.biochi.2019.01.001. Epub 2019 Jan 3.
573 Toxic effects of Cr(VI) on the bovine hemoglobin and human vascular endothelial cells: Molecular interaction and cell damage.Chemosphere. 2019 May;222:355-363. doi: 10.1016/j.chemosphere.2019.01.137. Epub 2019 Jan 24.
574 The versatility and paradox of GDF 11.Pharmacol Ther. 2017 Jul;175:28-34. doi: 10.1016/j.pharmthera.2017.02.032. Epub 2017 Feb 14.
575 Human liver fatty acid binding protein (hFABP1) gene is regulated by liver-enriched transcription factors HNF3 and C/EBP.Biochimie. 2012 Feb;94(2):384-92. doi: 10.1016/j.biochi.2011.08.006. Epub 2011 Aug 16.
576 An enzyme-linked immunosorbent assay for measuring GPIHBP1 levels in human plasma orserum.J Clin Lipidol. 2018 Jan-Feb;12(1):203-210.e1. doi: 10.1016/j.jacl.2017.10.022. Epub 2017 Nov 1.
577 Role of glycine 221 in catalytic activity of hyaluronan-binding protein 2.J Biol Chem. 2017 Apr 14;292(15):6381-6388. doi: 10.1074/jbc.M116.757849. Epub 2017 Feb 27.
578 Decarbromodiphenyl ether (BDE-209) promotes monocyte-endothelial adhesion in cultured human aortic endothelial cells through upregulating intercellular adhesion molecule-1.Environ Res. 2019 Feb;169:62-71. doi: 10.1016/j.envres.2018.10.035. Epub 2018 Nov 1.
579 Novel Ce(III)-Metal Organic Framework with a Luminescent Property To Fabricate an Electrochemiluminescence Immunosensor.ACS Appl Mater Interfaces. 2020 Jan 8;12(1):338-346. doi: 10.1021/acsami.9b19246. Epub 2019 Dec 27.
580 Association of heat shock protein70-2 (HSP70-2) gene polymorphism with obesity.Ann Hum Biol. 2016 Nov;43(6):542-546. doi: 10.3109/03014460.2015.1119309. Epub 2016 Feb 10.
581 Psychiatric disorders and cardiovascular diseases during the diagnostic workup of potential breast cancer: a population-based cohort study in Skne, Sweden.Breast Cancer Res. 2019 Dec 10;21(1):139. doi: 10.1186/s13058-019-1232-y.
582 Proteomics based identification of KDM5 histone demethylases associated with cardiovascular disease.EBioMedicine. 2019 Mar;41:91-104. doi: 10.1016/j.ebiom.2019.02.040. Epub 2019 Feb 28.
583 CardioVAI: An automatic implementation of ACMG-AMP variant interpretation guidelines in the diagnosis of cardiovascular diseases.Hum Mutat. 2018 Dec;39(12):1835-1846. doi: 10.1002/humu.23665. Epub 2018 Oct 19.
584 Anti-fibrotic effects of curcumin and some of its analogues in the heart.Heart Fail Rev. 2020 Sep;25(5):731-743. doi: 10.1007/s10741-019-09854-6.
585 Kidney function, proteinuria and breast arterial calcification in women without clinical cardiovascular disease: The MINERVA study.PLoS One. 2019 Jan 17;14(1):e0210973. doi: 10.1371/journal.pone.0210973. eCollection 2019.
586 GPER blockers as Nox downregulators: A new drug class to target chronic non-communicable diseases.J Steroid Biochem Mol Biol. 2018 Feb;176:82-87. doi: 10.1016/j.jsbmb.2017.03.019. Epub 2017 Mar 23.
587 Midregional pro-atrial natriuretic peptide, an important member of the natriuretic peptide family: potential role in diagnosis and prognosis of cardiovascular disease.J Int Med Res. 2018 Aug;46(8):3017-3029. doi: 10.1177/0300060518786907. Epub 2018 Jul 20.
588 Pregnancy-associated plasma protein-A predicts survival in end-stage renal disease-confounding and modifying effects of cardiovascular disease, body composition and inflammation.Nephrol Dial Transplant. 2018 Jun 1;33(6):971-977. doi: 10.1093/ndt/gfx215.
589 PEAR1 is not a major susceptibility gene for cardiovascular disease in a Flemish population.BMC Med Genet. 2017 Apr 27;18(1):45. doi: 10.1186/s12881-017-0411-x.
590 PHACTR1 and SLC22A3 gene polymorphisms are associated with reduced coronary artery disease risk in the male Chinese Han population.Oncotarget. 2017 Jan 3;8(1):658-663. doi: 10.18632/oncotarget.13506.
591 Gypenoside XVII prevents atherosclerosis by attenuating endothelial apoptosis and oxidative stress: insight into the ERalpha-mediated PI3K/Akt pathway. Int J Mol Sci. 2017 Feb 9;18(2). pii: E77.
592 Crystal structure and catalytic activity of the PPM1K N94K mutant.J Neurochem. 2019 Feb;148(4):550-560. doi: 10.1111/jnc.14631. Epub 2019 Jan 3.
593 The Effectiveness of Scoring Systems in the Prediction of Diagnosis-Based Mortality.Ther Apher Dial. 2019 Oct;23(5):418-424. doi: 10.1111/1744-9987.12780. Epub 2019 Feb 10.
594 Economic modelling of costs associated with outcomes reported for type 2 diabetes mellitus (T2DM) patients in the CANVAS and EMPA-REG cardiovascular outcomes trials.J Med Econ. 2019 Mar;22(3):280-287. doi: 10.1080/13696998.2018.1562817. Epub 2019 Jan 11.
595 The circular RNA ACR attenuates myocardial ischemia/reperfusion injury by suppressing autophagy via modulation of the Pink1/ FAM65B pathway.Cell Death Differ. 2019 Jul;26(7):1299-1315. doi: 10.1038/s41418-018-0206-4. Epub 2018 Oct 22.
596 RING finger protein 10 attenuates vascular restenosis by inhibiting vascular smooth muscle cell hyperproliferation in vivo and vitro.IUBMB Life. 2019 May;71(5):632-642. doi: 10.1002/iub.1995. Epub 2018 Dec 30.
597 Twelve weeks of low volume sprint interval training improves cardio-metabolic health outcomes in overweight females.J Sports Sci. 2019 Jun;37(11):1257-1264. doi: 10.1080/02640414.2018.1554615. Epub 2018 Dec 18.
598 ITM support for patients with chronic respiratory and cardiovascular diseases: a protocol for a randomised controlled trial.BMJ Open. 2019 Mar 1;9(3):e023863. doi: 10.1136/bmjopen-2018-023863.
599 Does SOD3 R213G Homozygosity Influence Morbidity, Mortality, and Lung Function in the General Population?.Antioxid Redox Signal. 2016 May 20;24(15):884-91. doi: 10.1089/ars.2016.6629. Epub 2016 Feb 22.
600 Copy number variation analysis in bicuspid aortic valve-related aortopathy identifies TBX20 as a contributing gene.Eur J Hum Genet. 2019 Jul;27(7):1033-1043. doi: 10.1038/s41431-019-0364-y. Epub 2019 Feb 28.
601 Testin protects against cardiac hypertrophy by targeting a calcineurin-dependent signalling pathway.J Cell Mol Med. 2019 Jan;23(1):328-339. doi: 10.1111/jcmm.13934. Epub 2018 Nov 22.
602 Silencing salusin ameliorates heart failure in aged spontaneously hypertensive rats by ROS-relative MAPK/NF-B pathways in the paraventricular nucleus.Int J Cardiol. 2019 Apr 1;280:142-151. doi: 10.1016/j.ijcard.2018.12.020. Epub 2018 Dec 7.
603 TRIB1 is a positive regulator of hepatocyte nuclear factor 4-alpha.Sci Rep. 2017 Jul 17;7(1):5574. doi: 10.1038/s41598-017-05768-1.
604 A Drosophila model of insulin resistance associated with the human TRIB3 Q/R polymorphism.Dis Model Mech. 2017 Dec 19;10(12):1453-1464. doi: 10.1242/dmm.030619.
605 Plasma proteomic analysis reveals altered protein abundances in cardiovascular disease.J Transl Med. 2018 Apr 17;16(1):104. doi: 10.1186/s12967-018-1476-9.
606 Lysine pathway metabolites and the risk of type 2 diabetes and cardiovascular disease in the PREDIMED study: results from two case-cohort studies.Cardiovasc Diabetol. 2019 Nov 13;18(1):151. doi: 10.1186/s12933-019-0958-2.
607 AIP1-mediated stress signaling in atherosclerosis and arteriosclerosis.Curr Atheroscler Rep. 2015 May;17(5):503. doi: 10.1007/s11883-015-0503-z.
608 Type 2 diabetes associated variants of KCNQ1 strongly confer the risk of cardiovascular disease among the Saudi Arabian population.Genet Mol Biol. 2017 Jul-Sep;40(3):586-590. doi: 10.1590/1678-4685-GMB-2017-0005. Epub 2017 Aug 31.
609 Genetic variants in eleven telomere-associated genes and the risk of incident cardio/cerebrovascular disease: The Women's Genome Health Study.Clin Chim Acta. 2011 Jan 14;412(1-2):199-202. doi: 10.1016/j.cca.2010.10.003. Epub 2010 Oct 16.
610 Identification of ACOX2 as a shared genetic risk factor for preeclampsia and cardiovascular disease.Eur J Hum Genet. 2011 Jul;19(7):796-800. doi: 10.1038/ejhg.2011.19. Epub 2011 Feb 23.
611 Association of acid phosphatase locus 1*C allele with the risk of cardiovascular events in rheumatoid arthritis patients.Arthritis Res Ther. 2011 Jul 18;13(4):R116. doi: 10.1186/ar3401.
612 Adverse lipid profile elevates risk for subarachnoid hemorrhage: Aprospective population-based cohort study.Atherosclerosis. 2018 Jul;274:112-119. doi: 10.1016/j.atherosclerosis.2018.05.011. Epub 2018 May 5.
613 Plasma lipid composition and risk of developing cardiovascular disease.PLoS One. 2013 Aug 15;8(8):e71846. doi: 10.1371/journal.pone.0071846. eCollection 2013.
614 Androgen inhibits key atherosclerotic processes by directly activating ADTRP transcription.Biochim Biophys Acta Mol Basis Dis. 2017 Sep;1863(9):2319-2332. doi: 10.1016/j.bbadis.2017.06.015. Epub 2017 Jun 20.
615 Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium.PLoS One. 2015 Oct 30;10(10):e0140496. doi: 10.1371/journal.pone.0140496. eCollection 2015.
616 Association of Rheumatoid Factors With Subclinical and Clinical Atherosclerosis in African American Women: The Multiethnic Study of Atherosclerosis.Arthritis Care Res (Hoboken). 2017 Feb;69(2):166-174. doi: 10.1002/acr.22930.
617 A comprehensive review on the potential therapeutic benefits of phosphodiesterase inhibitors on cardiovascular diseases.Biomed Pharmacother. 2017 Oct;94:541-556. doi: 10.1016/j.biopha.2017.07.084. Epub 2017 Aug 3.
618 High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased K(m)): relevance to genetic disease and polymorphisms.Am J Clin Nutr. 2002 Apr;75(4):616-58. doi: 10.1093/ajcn/75.4.616.
619 ABH and Lewis histo-blood group antigens, a model for the meaning of oligosaccharide diversity in the face of a changing world.Biochimie. 2001 Jul;83(7):565-73. doi: 10.1016/s0300-9084(01)01321-9.
620 Reduced biliary sterol output with no change in total faecal excretion in mice expressing a human apolipoprotein A-I variant.Liver Int. 2012 Oct;32(9):1363-71. doi: 10.1111/j.1478-3231.2012.02855.x. Epub 2012 Jul 29.
621 The evolving role of ankyrin-B in cardiovascular disease.Heart Rhythm. 2017 Dec;14(12):1884-1889. doi: 10.1016/j.hrthm.2017.07.032. Epub 2017 Jul 29.
622 Ankyrin Repeat Domain 1 Protein: A Functionally Pleiotropic Protein with Cardiac Biomarker Potential.Int J Mol Sci. 2017 Jun 26;18(7):1362. doi: 10.3390/ijms18071362.
623 Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency.Arterioscler Thromb Vasc Biol. 2019 Mar;39(3):373-386. doi: 10.1161/ATVBAHA.118.311931.
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625 Polymorphism in disease-related apolipoprotein C-II amyloid fibrils: a structural model for rod-like fibrils.FEBS J. 2018 Aug;285(15):2799-2812. doi: 10.1111/febs.14517. Epub 2018 Jun 9.
626 Apolipoprotein L6, induced in atherosclerotic lesions, promotes apoptosis and blocks Beclin 1-dependent autophagy in atherosclerotic cells.J Biol Chem. 2011 Aug 5;286(31):27389-98. doi: 10.1074/jbc.M110.210245. Epub 2011 Jun 6.
627 Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis.J Clin Invest. 2017 Dec 1;127(12):4516-4526. doi: 10.1172/JCI92702. Epub 2017 Nov 13.
628 Circulating Branched-Chain Amino Acids and Incident Cardiovascular Disease in a Prospective Cohort of US Women.Circ Genom Precis Med. 2018 Apr;11(4):e002157. doi: 10.1161/CIRCGEN.118.002157.
629 Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis.Nat Commun. 2017 Aug 30;8(1):393. doi: 10.1038/s41467-017-00517-4.
630 Six-Year Incidence and Risk Factors of Age-Related Macular Degeneration in Singaporean Indians: The Singapore Indian Eye Study.Sci Rep. 2018 Jun 11;8(1):8869. doi: 10.1038/s41598-018-27202-w.
631 Outcomes of liver transplantation in pediatric recipients with cardiovascular disease.Pediatr Transplant. 2018 Feb;22(1). doi: 10.1111/petr.13081. Epub 2017 Nov 12.
632 Value of the arterial stiffness index and ankle brachial index in subclinical atherosclerosis screening in healthy community-dwelling individuals.BMC Public Health. 2019 Jan 15;19(1):65. doi: 10.1186/s12889-019-6398-9.
633 Comparison of the Effects of Melatonin and Oxazepam on Anxiety Levels and Sleep Quality in Patients With ST-Segment-Elevation Myocardial Infarction Following Primary Percutaneous Coronary Intervention: A Randomized Clinical Trial.Ann Pharmacother. 2018 Oct;52(10):949-955. doi: 10.1177/1060028018776608. Epub 2018 May 11.
634 Nutritional regulation of coupling factor 6, a novel vasoactive and proatherogenic peptide.Nutrition. 2017 May;37:74-78. doi: 10.1016/j.nut.2016.07.017. Epub 2016 Aug 6.
635 A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy.Cell Death Dis. 2015 Oct 29;6(10):e1948. doi: 10.1038/cddis.2015.280.
636 Genetic predictors of cardiovascular morbidity in Bardet-Biedl syndrome.Clin Genet. 2015 Apr;87(4):343-9. doi: 10.1111/cge.12373. Epub 2014 Apr 8.
637 Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium.Circ Cardiovasc Genet. 2012 Feb 1;5(1):81-90. doi: 10.1161/CIRCGENETICS.111.959817. Epub 2011 Nov 8.
638 An integrated genomic-transcriptomic approach supports a role for the proto-oncogene BCL3 in atherosclerosis.Thromb Haemost. 2015 Mar;113(3):655-63. doi: 10.1160/TH14-05-0466. Epub 2014 Nov 6.
639 Whole flour and protein hydrolysate from common beans reduce the inflammation in BALB/c mice fed with high fat high cholesterol diet.Food Res Int. 2019 Aug;122:330-339. doi: 10.1016/j.foodres.2019.04.013. Epub 2019 Apr 14.
640 Links between Atherosclerosis and Osteoporosis in Middle Aged and Elderly Men.J Nutr Health Aging. 2018;22(6):639-644. doi: 10.1007/s12603-018-1039-z.
641 Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease.Atherosclerosis. 2003 Apr;167(2):205-14. doi: 10.1016/s0021-9150(03)00010-8.
642 Dronedarone exerts anticoagulant and antiplatelet effects independently of its antiarrhythmic actions.Atherosclerosis. 2017 Nov;266:81-86. doi: 10.1016/j.atherosclerosis.2017.09.029. Epub 2017 Sep 28.
643 The single nucleotide polymorphisms in BRAP decrease the risk of metabolic syndrome in a Chinese young adult population.Diab Vasc Dis Res. 2013 May;10(3):202-7. doi: 10.1177/1479164112455535. Epub 2012 Sep 10.
644 ICU-treated influenza A(H1N1) pdm09 infections more severe post pandemic than during 2009 pandemic: a retrospective analysis.BMC Infect Dis. 2017 Nov 21;17(1):728. doi: 10.1186/s12879-017-2829-3.
645 PON1 lactonase activity and its association with cardiovascular disease.Clin Chim Acta. 2020 Jan;500:47-53. doi: 10.1016/j.cca.2019.09.016. Epub 2019 Oct 15.
646 The role of adiponectin and adipolin as anti-inflammatory adipokines in the formation of macrophage foam cells and their association with cardiovascular diseases.Clin Biochem. 2018 Apr;54:1-10. doi: 10.1016/j.clinbiochem.2018.02.008. Epub 2018 Feb 13.
647 Serum Levels of Complement-C1q/Tumor Necrosis Factor-Related Protein-3 Decreased in Patients With Acute Aortic Dissection.Am J Cardiol. 2018 Oct 1;122(7):1244-1248. doi: 10.1016/j.amjcard.2018.06.024. Epub 2018 Jul 4.
648 CAMTA1 T polymorphism is associated with neuropsychological test performance in older adults with cardiovascular disease.Psychogeriatrics. 2011 Sep;11(3):135-40. doi: 10.1111/j.1479-8301.2011.00357.x. Epub 2011 Jun 15.
649 Calpain-5 gene variants are associated with diastolic blood pressure and cholesterol levels.BMC Med Genet. 2007 Jan 16;8:1. doi: 10.1186/1471-2350-8-1.
650 Association between caspase recruitment domain-containing protein 8 rs2043211 polymorphism and cardiovascular disease susceptibility: A systematic review and meta-analysis.Anatol J Cardiol. 2018 Aug;20(2):70-76. doi: 10.14744/AnatolJCardiol.2018.32650.
651 Associations of blood pressure categories defined by 2017 ACC/AHA guidelines with mortality in China: Pooled results from three prospective cohorts.Eur J Prev Cardiol. 2020 Mar;27(4):345-354. doi: 10.1177/2047487319862066. Epub 2019 Jul 9.
652 CCL7 Is a Negative Regulator of Cutaneous Inflammation Following Leishmania major Infection.Front Immunol. 2019 Jan 8;9:3063. doi: 10.3389/fimmu.2018.03063. eCollection 2018.
653 Genetic association of the CCR5 region with lipid levels in at-risk cardiovascular patients.Circ Cardiovasc Genet. 2010 Apr;3(2):162-8. doi: 10.1161/CIRCGENETICS.109.897793. Epub 2010 Feb 3.
654 CCAAT/enhancer-binding protein delta promotes intracellular lipid accumulation in M1 macrophages of vascular lesions.Cardiovasc Res. 2017 Sep 1;113(11):1376-1388. doi: 10.1093/cvr/cvx134.
655 MIF family cytokines in cardiovascular diseases and prospects for precision-based therapeutics.Expert Opin Ther Targets. 2017 Jul;21(7):671-683. doi: 10.1080/14728222.2017.1336227.
656 A gene variant in CERS2 is associated with rate of increase in albuminuria in patients with diabetes from ONTARGET and TRANSCEND.PLoS One. 2014 Sep 19;9(9):e106631. doi: 10.1371/journal.pone.0106631. eCollection 2014.
657 Cheese consumption and risk of cardiovascular disease: a meta-analysis of prospective studies.Eur J Nutr. 2017 Dec;56(8):2565-2575. doi: 10.1007/s00394-016-1292-z. Epub 2016 Aug 12.
658 Common functional genetic variants in catecholamine storage vesicle protein promoter motifs interact to trigger systemic hypertension.J Am Coll Cardiol. 2010 Apr 6;55(14):1463-75. doi: 10.1016/j.jacc.2009.11.064.
659 Association of CILP2 and ACE gene polymorphisms with cardiovascular risk factors in Slovak midlife women.Biomed Res Int. 2013;2013:634207. doi: 10.1155/2013/634207. Epub 2013 Nov 20.
660 Interactions between mitoNEET and NAF-1 in cells.PLoS One. 2017 Apr 20;12(4):e0175796. doi: 10.1371/journal.pone.0175796. eCollection 2017.
661 The retinoic acid receptor-related orphan receptor positively regulates tight junction protein claudin domain-containing 1 mRNA expression in human brain endothelial cells.J Biochem. 2017 May 1;161(5):441-450. doi: 10.1093/jb/mvw092.
662 Relationship between carnosinase gene CNDP1 leucine repeat polymorphism and the clinical outcome of Chinese PD patients.Clin Nephrol. 2010 Nov;74(5):343-5. doi: 10.5414/cnp74343.
663 Cardiovascular disease and use of contemporary protease inhibitors: the D:A:D international prospective multicohort study.Lancet HIV. 2018 Jun;5(6):e291-e300. doi: 10.1016/S2352-3018(18)30043-2. Epub 2018 May 3.
664 Relationship between Long Interspersed Nuclear Element-1 DNA Methylation in Leukocytes and Dyslipidemia in the Japanese General Population.J Atheroscler Thromb. 2018 Dec 1;25(12):1231-1239. doi: 10.5551/jat.43570. Epub 2018 Apr 7.
665 Genetic architecture of human plasma lipidome and its link to cardiovascular disease.Nat Commun. 2019 Sep 24;10(1):4329. doi: 10.1038/s41467-019-11954-8.
666 Analysis of a gene co-expression network establishes robust association between Col5a2 and ischemic heart disease.BMC Med Genomics. 2013 Apr 10;6:13. doi: 10.1186/1755-8794-6-13.
667 RAPIDSNPs: A new computational pipeline for rapidly identifying key genetic variants reveals previously unidentified SNPs that are significantly associated with individual platelet responses.PLoS One. 2017 Apr 25;12(4):e0175957. doi: 10.1371/journal.pone.0175957. eCollection 2017.
668 Role of the COP9 Signalosome (CSN) in Cardiovascular Diseases.Biomolecules. 2019 Jun 5;9(6):217. doi: 10.3390/biom9060217.
669 Localization of the mosaic transmembrane serine protease corin to heart myocytes.Eur J Biochem. 2000 Dec;267(23):6931-7. doi: 10.1046/j.1432-1033.2000.01806.x.
670 Cortistatin exerts antiproliferation and antimigration effects in vascular smooth muscle cells stimulated by Ang II through suppressing ERK1/2, p38 MAPK, JNK and ERK5 signaling pathways.Ann Transl Med. 2019 Oct;7(20):561. doi: 10.21037/atm.2019.09.45.
671 Systems Pharmacogenomics Finds RUNX1 Is an Aspirin-Responsive Transcription Factor Linked to Cardiovascular Disease and Colon Cancer.EBioMedicine. 2016 Sep;11:157-164. doi: 10.1016/j.ebiom.2016.08.021. Epub 2016 Aug 14.
672 Pre-hypertension, pre-diabetes or both: which is best at predicting cardiovascular events in the long term?.J Hum Hypertens. 2017 Jun;31(6):382-387. doi: 10.1038/jhh.2016.42. Epub 2016 Jun 23.
673 CRIM1 is necessary for coronary vascular endothelial cell development and homeostasis.J Mol Histol. 2017 Feb;48(1):53-61. doi: 10.1007/s10735-016-9702-3. Epub 2016 Nov 1.
674 Identification of differentially methylated BRCA1 and CRISP2 DNA regions as blood surrogate markers for cardiovascular disease.Sci Rep. 2017 Jul 11;7(1):5120. doi: 10.1038/s41598-017-03434-0.
675 Polymorphism of bovine beta-casein and its potential effect on human health.J Appl Genet. 2007;48(3):189-98. doi: 10.1007/BF03195213.
676 Cystatin B, cathepsin L and D related to surrogate markers for cardiovascular disease in children.PLoS One. 2017 Nov 17;12(11):e0187494. doi: 10.1371/journal.pone.0187494. eCollection 2017.
677 The Preterm Heart in Childhood: Left Ventricular Structure, Geometry, and Function Assessed by Echocardiography in 6-Year-Old Survivors of Periviable Births.J Am Heart Assoc. 2018 Jan 20;7(2):e007742. doi: 10.1161/JAHA.117.007742.
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679 Candidate gene analysis in the So Paulo Epidemiologic Sleep Study (EPISONO) shows an association of variant in PDE4D and sleepiness.Sleep Med. 2018 Jul;47:106-112. doi: 10.1016/j.sleep.2017.12.010. Epub 2018 Jan 12.
680 Cytoglobin regulates blood pressure and vascular tone through nitric oxide metabolism in the vascular wall.Nat Commun. 2017 Apr 10;8:14807. doi: 10.1038/ncomms14807.
681 Analysis of mitochondrial DNA heteroplasmic mutations A1555G, C3256T, T3336C, 5178, G12315A, G13513A, G14459A, G14846 and G15059A in CHD patients with the history of myocardial infarction.Exp Mol Pathol. 2016 Feb;100(1):87-91. doi: 10.1016/j.yexmp.2015.12.003. Epub 2015 Dec 3.
682 Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese.PLoS One. 2014 Jan 20;9(1):e84770. doi: 10.1371/journal.pone.0084770. eCollection 2014.
683 NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets.Nat Rev Cardiol. 2020 Mar;17(3):170-194. doi: 10.1038/s41569-019-0260-8. Epub 2019 Oct 7.
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686 Effects of visceral adipose tissue reduction on CVD risk factors independent of weight loss: The Look AHEAD study.Endocr Res. 2017 May;42(2):86-95. doi: 10.1080/07435800.2016.1194856. Epub 2016 Jun 28.
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699 Gene expression levels of elastin and fibulin-5 according to differences between carotid plaque regions.In Vivo. 2015 Mar-Apr;29(2):229-35.
700 The benefits of angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers combined with calcium channel blockers on metabolic, renal, and cardiovascular outcomes in hypertensive patients: a meta-analysis.Int Urol Nephrol. 2018 Dec;50(12):2261-2278. doi: 10.1007/s11255-018-1991-x. Epub 2018 Oct 15.
701 Truncating FLNC Mutations Are Associated With High-Risk Dilated and Arrhythmogenic Cardiomyopathies.J Am Coll Cardiol. 2016 Dec 6;68(22):2440-2451. doi: 10.1016/j.jacc.2016.09.927.
702 Dendritic cell-targeting DNA-based nasal adjuvants for protective mucosal immunity to Streptococcus pneumoniae.Microbiol Immunol. 2017 Jun;61(6):195-205. doi: 10.1111/1348-0421.12487.
703 FoxO4 promotes myocardial ischemia-reperfusion injury: the role of oxidative stress-induced apoptosis.Am J Transl Res. 2018 Sep 15;10(9):2890-2900. eCollection 2018.
704 Mitophagy receptor FUNDC1 regulates mitochondrial homeostasis and protects the heart from I/R injury.Autophagy. 2017 Jun 3;13(6):1080-1081. doi: 10.1080/15548627.2017.1300224. Epub 2017 Mar 21.
705 Association of Genetic Variations in NRF2, NQO1, HMOX1, and MT with Severity of Coronary Artery Disease and Related Risk Factors.Cardiovasc Toxicol. 2020 Apr;20(2):176-189. doi: 10.1007/s12012-019-09544-7.
706 Mortality causes and trends associated with giant cell arteritis: analysis of the French national death certificate database (1980-2011).Rheumatology (Oxford). 2018 Jun 1;57(6):1047-1055. doi: 10.1093/rheumatology/key028.
707 Candidate gene polymorphism in cardiovascular disease: the BIP cohort.Isr Med Assoc J. 2006 Feb;8(2):103-5.
708 Glia maturation factor-gamma is preferentially expressed in microvascular endothelial and inflammatory cells and modulates actin cytoskeleton reorganization.Circ Res. 2006 Aug 18;99(4):424-33. doi: 10.1161/01.RES.0000237662.23539.0b. Epub 2006 Jul 27.
709 Series: Implications of the recent CVOTs in type 2 diabetes: Impact on guidelines: The endocrinologist point of view.Diabetes Res Clin Pract. 2020 Jan;159:107726. doi: 10.1016/j.diabres.2019.05.005. Epub 2019 May 18.
710 Blood-based omic profiling supports female susceptibility to tobacco smoke-induced cardiovascular diseases.Sci Rep. 2017 Feb 22;7:42870. doi: 10.1038/srep42870.
711 Novel DNA Methylation Sites Influence GPR15 Expression in Relation to Smoking.Biomolecules. 2018 Aug 20;8(3):74. doi: 10.3390/biom8030074.
712 20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (G(q)) to Affect Vascular Function and Trigger Hypertension.Circ Res. 2017 May 26;120(11):1776-1788. doi: 10.1161/CIRCRESAHA.116.310525. Epub 2017 Mar 21.
713 Pre-clinical model of severe glutathione peroxidase-3 deficiency and chronic kidney disease results in coronary artery thrombosis and depressed left ventricular function.Nephrol Dial Transplant. 2018 Jun 1;33(6):923-934. doi: 10.1093/ndt/gfx304.
714 Genotype at the P554L variant of the hexose-6 phosphate dehydrogenase gene is associated with carotid intima-medial thickness.PLoS One. 2011;6(8):e23248. doi: 10.1371/journal.pone.0023248. Epub 2011 Aug 12.
715 Association of A1C with cardiovascular disease and metabolic syndrome in Asian Indians with normal glucose tolerance.Diabetes Care. 2007 Jun;30(6):1527-32. doi: 10.2337/dc06-2414. Epub 2007 Mar 10.
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717 The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease.Nat Genet. 1999 Aug;22(4):347-51. doi: 10.1038/11914.
718 Associations Between Measures of Sarcopenic Obesity and Risk of Cardiovascular Disease and Mortality: A Cohort Study and Mendelian Randomization Analysis Using the UK Biobank.J Am Heart Assoc. 2019 Jul 2;8(13):e011638. doi: 10.1161/JAHA.118.011638. Epub 2019 Jun 21.
719 HHIPL-1 (rs2895811) gene polymorphism is associated with cardiovascular risk factors and cardiometabolic parameters in Mexicans patients with myocardial infarction.Gene. 2018 Jul 15;663:34-40. doi: 10.1016/j.gene.2018.04.030. Epub 2018 Apr 12.
720 Day-by-Day Variability of Home Blood Pressure and Incident Cardiovascular Disease in Clinical Practice: The J-HOP Study (Japan Morning Surge-Home Blood Pressure).Hypertension. 2018 Jan;71(1):177-184. doi: 10.1161/HYPERTENSIONAHA.117.10385. Epub 2017 Nov 13.
721 Contribution of CDKAL1 rs7756992 and IGF2BP2 rs4402960 polymorphisms in type 2 diabetes, diabetic complications, obesity risk and hypertension in the Tunisian population.J Diabetes. 2015 Jan;7(1):102-13. doi: 10.1111/1753-0407.12147. Epub 2014 Apr 21.
722 Case report: low circulating IGF-I levels due to Acid-Labile Subunit deficiency in adulthood are not associated with early development of atherosclerosis and impaired heart function.Growth Horm IGF Res. 2011 Aug;21(4):233-7. doi: 10.1016/j.ghir.2011.05.004. Epub 2011 Jun 12.
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724 Long-term effects of total and source-specific particulate air pollution on incident cardiovascular disease in Gothenburg, Sweden.Environ Res. 2017 Oct;158:61-71. doi: 10.1016/j.envres.2017.05.036. Epub 2017 Jun 8.
725 Association of an INSIG2 obesity allele with cardiovascular phenotypes is gender and age dependent.BMC Cardiovasc Disord. 2010 Sep 29;10:46. doi: 10.1186/1471-2261-10-46.
726 Modulation of vascular endothelial cell senescence by integrin 4.J Cell Physiol. 2010 Nov;225(3):673-81. doi: 10.1002/jcp.22262.
727 KIAA1462, a coronary artery disease associated gene, is a candidate gene for late onset Alzheimer disease in APOE carriers.PLoS One. 2013 Dec 12;8(12):e82194. doi: 10.1371/journal.pone.0082194. eCollection 2013.
728 Impact of high-density lipoprotein 3 cholesterol subfraction on periprocedural myocardial injury in patients who underwent elective percutaneous coronary intervention.Lipids Health Dis. 2018 Feb 2;17(1):21. doi: 10.1186/s12944-018-0670-3.
729 Genetic Variant of Kalirin Gene Is Associated with Ischemic Stroke in a Chinese Han Population.Biomed Res Int. 2017;2017:6594271. doi: 10.1155/2017/6594271. Epub 2017 Jun 19.
730 Association of KCNQ1, KCNE1, KCNH2 and SCN5A polymorphisms with QTc interval length in a healthy population.Eur J Hum Genet. 2005 Nov;13(11):1213-22. doi: 10.1038/sj.ejhg.5201489.
731 Phase 3 DREAM-HF Trial of Mesenchymal Precursor Cells in Chronic Heart Failure.Circ Res. 2019 Jul 19;125(3):265-281. doi: 10.1161/CIRCRESAHA.119.314951. Epub 2019 Jul 18.
732 FGF23-Klotho axis in patients with rheumatoid arthritis.Clin Exp Rheumatol. 2020 Jan-Feb;38(1):50-57. Epub 2019 Apr 16.
733 Krppel-like factor 14, a coronary artery disease associated transcription factor, inhibits endothelial inflammation via NF-B signaling pathway.Atherosclerosis. 2018 Nov;278:39-48. doi: 10.1016/j.atherosclerosis.2018.09.018. Epub 2018 Sep 15.
734 ENU-induced mutation in the DNA-binding domain of KLF3 reveals important roles for KLF3 in cardiovascular development and function in mice.PLoS Genet. 2013;9(7):e1003612. doi: 10.1371/journal.pgen.1003612. Epub 2013 Jul 11.
735 Regulatory polymorphism in transcription factor KLF5 at the MEF2 element alters the response to angiotensin II and is associated with human hypertension.FASEB J. 2010 Jun;24(6):1780-8. doi: 10.1096/fj.09-146589. Epub 2010 Jan 19.
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737 Female sex, high soluble CD163, and low HDL-cholesterol were associated with high galectin-3 binding protein in type 1 diabetes.Biol Sex Differ. 2019 Nov 21;10(1):51. doi: 10.1186/s13293-019-0268-0.
738 Hepatic lipase, genetically elevated high-density lipoprotein, and risk of ischemic cardiovascular disease.J Clin Endocrinol Metab. 2009 Apr;94(4):1264-73. doi: 10.1210/jc.2008-1342. Epub 2008 Dec 16.
739 LOXL1 gene sequence variants and vascular disease in exfoliation syndrome and exfoliative glaucoma.J Glaucoma. 2011 Mar;20(3):143-7. doi: 10.1097/IJG.0b013e3181d9d8dd.
740 Genetic variants within the LPIN1 gene, encoding lipin, are influencing phenotypes of the metabolic syndrome in humans.Diabetes. 2008 Jan;57(1):209-17. doi: 10.2337/db07-0083. Epub 2007 Oct 16.
741 ApoER2 (Apolipoprotein E Receptor-2) Deficiency Accelerates Smooth Muscle Cell Senescence via Cytokinesis Impairment and Promotes Fibrotic Neointima After Vascular Injury.Arterioscler Thromb Vasc Biol. 2019 Oct;39(10):2132-2144. doi: 10.1161/ATVBAHA.119.313194. Epub 2019 Aug 15.
742 Determination of alpha-2-MRAP gene polymorphisms in nephrolithiasis patients.Int J Biol Macromol. 2017 Dec;105(Pt 1):1324-1327. doi: 10.1016/j.ijbiomac.2017.07.167. Epub 2017 Jul 29.
743 Effect of LSR polymorphism on blood lipid levels and age-specific epistatic interaction with the APOE common polymorphism.Clin Genet. 2018 Apr;93(4):846-852. doi: 10.1111/cge.13181.
744 Silica exposure increases the risk of stroke but not myocardial infarction-A retrospective cohort study.PLoS One. 2018 Feb 26;13(2):e0192840. doi: 10.1371/journal.pone.0192840. eCollection 2018.
745 Mitochondrial Ubiquitin Ligase in Cardiovascular Disorders.Adv Exp Med Biol. 2017;982:327-333. doi: 10.1007/978-3-319-55330-6_17.
746 Distinct Longitudinal Associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 With Endothelial Dysfunction and Intima-Media Thickness: The Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study.Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1278-85. doi: 10.1161/ATVBAHA.115.306552. Epub 2016 Apr 7.
747 Sensitive point-of-care monitoring of cardiac biomarker myoglobin using aptamer and ubiquitous personal glucose meter.Biosens Bioelectron. 2015 Feb 15;64:161-4. doi: 10.1016/j.bios.2014.08.079. Epub 2014 Sep 3.
748 Metabolic syndrome but not genetic polymorphisms known to induce NAFLD predicts increased total mortality in subjects with NAFLD (OPERA study).Scand J Clin Lab Invest. 2020 Feb-Apr;80(2):106-113. doi: 10.1080/00365513.2019.1700428. Epub 2019 Dec 18.
749 MEF2A alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells.BMC Mol Biol. 2019 Mar 18;20(1):8. doi: 10.1186/s12867-019-0125-z.
750 MEIS1 variant as a determinant of autonomic imbalance in Restless Legs Syndrome.Sci Rep. 2017 Apr 20;7:46620. doi: 10.1038/srep46620.
751 Risk and Age of Cardiovascular Event in Women with Metabolic Syndrome: Menopause Age in Focus.Metab Syndr Relat Disord. 2018 Apr;16(3):127-134. doi: 10.1089/met.2017.0096. Epub 2018 Feb 13.
752 Localization of microfibrillar-associated protein 4 (MFAP4) in human tissues: clinical evaluation of serum MFAP4 and its association with various cardiovascular conditions.PLoS One. 2013 Dec 13;8(12):e82243. doi: 10.1371/journal.pone.0082243. eCollection 2013.
753 Quercetin-Induced AMP-Activated Protein Kinase Activation Attenuates Vasoconstriction Through LKB1-AMPK Signaling Pathway.J Med Food. 2018 Feb;21(2):146-153. doi: 10.1089/jmf.2017.4052. Epub 2017 Oct 16.
754 Genetic and Environmental Biomarkers Associated with Triglyceride Levels in Two Groups of Slovak Women.Genet Test Mol Biomarkers. 2017 Jan;21(1):46-52. doi: 10.1089/gtmb.2016.0205. Epub 2016 Nov 17.
755 Abetalipoproteinemia: two case reports and literature review.Orphanet J Rare Dis. 2008 Jul 8;3:19. doi: 10.1186/1750-1172-3-19.
756 LncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription.Nat Commun. 2018 Jan 2;9(1):29. doi: 10.1038/s41467-017-02280-y.
757 Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins.Nucleic Acids Res. 2018 Jan 9;46(1):362-386. doi: 10.1093/nar/gkx1120.
758 Role of aberrant nitric oxide synthase-3 expression in cerebrovascular degeneration and vascular-mediated injury in Alzheimer's disease.Ann N Y Acad Sci. 2000 Apr;903:61-71. doi: 10.1111/j.1749-6632.2000.tb06351.x.
759 Atazanavir sulfate + cobicistat for the treatment of HIV infection.Expert Rev Anti Infect Ther. 2017 Jun;15(6):569-576. doi: 10.1080/14787210.2017.1323634. Epub 2017 May 9.
760 Genetic variation in NEDD4L, an epithelial sodium channel regulator, is associated with cardiovascular disease and cardiovascular death.J Hypertens. 2014 Feb;32(2):294-9. doi: 10.1097/HJH.0000000000000044.
761 Randomised controlled trial comparing uptake of NHS Health Check in response to standard letters, risk-personalised letters and telephone invitations.BMC Public Health. 2019 Feb 21;19(1):224. doi: 10.1186/s12889-019-6540-8.
762 Molecular Basis for Dysregulated Activation of NKX2-5 in the Vascular Remodeling of Systemic Sclerosis.Arthritis Rheumatol. 2018 Jun;70(6):920-931. doi: 10.1002/art.40419. Epub 2018 Apr 24.
763 Associations between NOS1AP single nucleotide polymorphisms (SNPs) and QT interval duration in four racial/ethnic groups in the Multi-Ethnic Study of Atherosclerosis (MESA).Ann Noninvasive Electrocardiol. 2013 Jan;18(1):29-40. doi: 10.1111/anec.12028.
764 Association between a dietary quality index based on the food standard agency nutrient profiling system and cardiovascular disease risk among French adults.Int J Cardiol. 2017 May 1;234:22-27. doi: 10.1016/j.ijcard.2017.02.092. Epub 2017 Feb 24.
765 Tacrolimus Concentration-to-Dose Ratios in Kidney Transplant Recipients and Relationship to Clinical Outcomes.Pharmacotherapy. 2019 Aug;39(8):827-836. doi: 10.1002/phar.2300. Epub 2019 Jul 18.
766 Lipoprotein(a) and Cardiovascular Risk Prediction Among Women.J Am Coll Cardiol. 2018 Jul 17;72(3):287-296. doi: 10.1016/j.jacc.2018.04.060. Epub 2018 Jul 9.
767 Metabolic and Cardiovascular Actions of Nesfatin-1: Implications in Health and Disease.Curr Pharm Des. 2017;23(10):1453-1464. doi: 10.2174/1381612823666170130154407.
768 O-GlcNAcase Fragment Discovery with Fluorescence Polarimetry.ACS Chem Biol. 2018 May 18;13(5):1353-1360. doi: 10.1021/acschembio.8b00183. Epub 2018 May 2.
769 Osteoglycin and Bone-a Systematic Review.Curr Osteoporos Rep. 2019 Oct;17(5):250-255. doi: 10.1007/s11914-019-00523-z.
770 Novel glucopyranoside C2-derived 1,2,3-triazoles displaying selective inhibition of O-GlcNAcase (OGA).Carbohydr Res. 2019 Jan 1;471:43-55. doi: 10.1016/j.carres.2018.10.007. Epub 2018 Oct 26.
771 Leptin increases mitochondrial OPA1 via GSK3-mediated OMA1 ubiquitination to enhance therapeutic effects of mesenchymal stem cell transplantation.Cell Death Dis. 2018 May 1;9(5):556. doi: 10.1038/s41419-018-0579-9.
772 Association of OSBPL11 gene polymorphisms with cardiovascular disease risk factors in obesity.Obesity (Silver Spring). 2009 Jul;17(7):1466-72. doi: 10.1038/oby.2009.71. Epub 2009 Mar 26.
773 Effects of statins on the secretion of human serum albumin in cultured HepG2 cells.J Biomed Sci. 2009 Mar 16;16(1):32. doi: 10.1186/1423-0127-16-32.
774 Pacsin 2 is required for the maintenance of a normal cardiac function in the developing mouse heart.Pharmacol Res. 2018 Feb;128:200-210. doi: 10.1016/j.phrs.2017.10.004. Epub 2017 Oct 28.
775 The role of the t-PA I/D and PAI-1 4G/5G polymorphisms in African-American adults with a diagnosis of myocardial infarction or venous thromboembolism.Thromb Res. 2000 Aug 1;99(3):223-30. doi: 10.1016/s0049-3848(00)00236-x.
776 A CBS haplotype and a polymorphism at the MSR gene are associated with cardiovascular disease in a Spanish case-control study.Clin Biochem. 2007 Aug;40(12):864-8. doi: 10.1016/j.clinbiochem.2007.04.008. Epub 2007 Apr 27.
777 Factor VIII, Protein C and Cardiovascular Disease Risk: The REasons for Geographic and Racial Differences in Stroke Study (REGARDS).Thromb Haemost. 2018 Jul;118(7):1305-1315. doi: 10.1055/s-0038-1655766. Epub 2018 Jun 11.
778 RNA-binding proteins heterogeneous nuclear ribonucleoprotein A1, E1, and K are involved in post-transcriptional control of collagen I and III synthesis.Circ Res. 2004 Nov 26;95(11):1058-66. doi: 10.1161/01.RES.0000149166.33833.08. Epub 2004 Oct 28.
779 Prenylcysteine oxidase 1, a pro-oxidant enzyme of low density lipoproteins.Front Biosci (Landmark Ed). 2018 Jan 1;23(6):1020-1037. doi: 10.2741/4631.
780 Intense Light-Mediated Circadian Cardioprotection via Transcriptional Reprogramming of the Endothelium.Cell Rep. 2019 Aug 6;28(6):1471-1484.e11. doi: 10.1016/j.celrep.2019.07.020.
781 PHLPP: a putative cellular target during insulin resistance and type 2 diabetes.J Endocrinol. 2017 Jun;233(3):R185-R198. doi: 10.1530/JOE-17-0081. Epub 2017 Apr 20.
782 Regulators of G protein signaling in cardiovascular function during pregnancy.Physiol Genomics. 2018 Aug 1;50(8):590-604. doi: 10.1152/physiolgenomics.00037.2018. Epub 2018 Apr 27.
783 Serum podocalyxin levels correlate with carotid intima media thickness, implicating its role as a novel biomarker for atherosclerosis.Sci Rep. 2018 Jan 10;8(1):245. doi: 10.1038/s41598-017-18647-6.
784 Pharmacogenetics of aspirin resistance: a comprehensive systematic review.Br J Clin Pharmacol. 2008 Aug;66(2):222-32. doi: 10.1111/j.1365-2125.2008.03183.x. Epub 2008 Apr 22.
785 Detrimental Effects of Testosterone Addition to Estrogen Therapy Involve Cytochrome P-450-Induced 20-HETE Synthesis in Aorta of Ovariectomized Spontaneously Hypertensive Rat (SHR), a Model of Postmenopausal Hypertension.Front Physiol. 2018 May 8;9:490. doi: 10.3389/fphys.2018.00490. eCollection 2018.
786 Epigenetic Regulatory Effect of Exercise on Glutathione Peroxidase 1 Expression in the Skeletal Muscle of Severely Dyslipidemic Mice.PLoS One. 2016 Mar 24;11(3):e0151526. doi: 10.1371/journal.pone.0151526. eCollection 2016.
787 SNPs rs10224002 in PRKAG2 may disturb gene expression and consequently affect hypertension.Mol Biol Rep. 2019 Apr;46(2):1617-1624. doi: 10.1007/s11033-019-04610-3. Epub 2019 Jan 28.
788 APOE 4 Carriers Show Delayed Recovery of Verbal Memory and Smaller Entorhinal Volume in the First Year After Ischemic Stroke.J Alzheimers Dis. 2019;71(1):245-259. doi: 10.3233/JAD-190566.
789 A coupled fluorescence-based assay for the detection of protein arginine N-methyltransferase 6 (PRMT6) enzymatic activity.Anal Biochem. 2018 Apr 15;547:7-13. doi: 10.1016/j.ab.2018.01.023. Epub 2018 Feb 2.
790 Astragaloside IV inhibits PMA-induced EPCR shedding through MAPKs and PKC pathway.Immunopharmacol Immunotoxicol. 2017 Jun;39(3):148-156. doi: 10.1080/08923973.2017.1306868. Epub 2017 Apr 3.
791 1,4-Dihydropyridine derivatives without Ca2+-antagonist activity up-regulate Psma6 mRNA expression in kidneys of intact and diabetic rats.Cell Biochem Funct. 2016 Jan;34(1):3-6. doi: 10.1002/cbf.3160. Epub 2015 Dec 4.
792 A Review of Cardiovascular Toxicity of Microcystins.Toxins (Basel). 2019 Aug 30;11(9):507. doi: 10.3390/toxins11090507.
793 Changes of serum pentraxin-3 and hypersensitive CRP levels during pregnancy and their relationship with gestational diabetes mellitus.PLoS One. 2019 Nov 13;14(11):e0224739. doi: 10.1371/journal.pone.0224739. eCollection 2019.
794 Coordination between NADPH oxidase and vascular peroxidase 1 promotes dysfunctions of endothelial progenitor cells in hypoxia-induced pulmonary hypertensive rats.Eur J Pharmacol. 2019 Aug 15;857:172459. doi: 10.1016/j.ejphar.2019.172459. Epub 2019 Jun 16.
795 Loss of Inverse Association between Framingham Risk Score and Estimated Glomerular Filtration Rate in Moderate to Severe Diabetic Kidney Disease.Arch Iran Med. 2019 Feb 1;22(2):91-98.
796 Adipokine Chemerin Stimulates Progression of Atherosclerosis in ApoE(-/-) Mice.Biomed Res Int. 2019 Oct 31;2019:7157865. doi: 10.1155/2019/7157865. eCollection 2019.
797 Obstructive Sleep Apnea during REM Sleep and Cardiovascular Disease.Am J Respir Crit Care Med. 2018 Mar 1;197(5):653-660. doi: 10.1164/rccm.201706-1112OC.
798 Association of regulator of G protein signaling (RGS5) gene variants and essential hypertension in Mongolian and Han populations.Genet Mol Res. 2015 Dec 21;14(4):17641-50. doi: 10.4238/2015.December.21.37.
799 Pathophysiological effects of RhoA and Rho-associated kinase on cardiovascular system.J Hypertens. 2016 Jan;34(1):3-10. doi: 10.1097/HJH.0000000000000768.
800 Serelaxin (recombinant human relaxin-2) treatment affects the endogenous synthesis of long chain poly-unsaturated fatty acids and induces substantial alterations of lipidome and metabolome profiles in rat cardiac tissue.Pharmacol Res. 2019 Jun;144:51-65. doi: 10.1016/j.phrs.2019.04.009. Epub 2019 Apr 5.
801 Extracellular Ribonucleic Acids (RNA) Enter the Stage in Cardiovascular Disease.Circ Res. 2016 Feb 5;118(3):469-79. doi: 10.1161/CIRCRESAHA.115.307961.
802 RYR3 gene polymorphisms and cardiovascular disease outcomes in the context of antihypertensive treatment.Pharmacogenomics J. 2013 Aug;13(4):330-4. doi: 10.1038/tpj.2012.22. Epub 2012 Jun 5.
803 Genome survey for loci that influence successful aging: results at 10-cM resolution.Am J Geriatr Psychiatry. 2007 Mar;15(3):184-93. doi: 10.1097/01.JGP.0000231681.89741.af. Epub 2006 Aug 11.
804 Septin4 as a novel binding partner of PARP1 contributes to oxidative stress induced human umbilical vein endothelial cells injure.Biochem Biophys Res Commun. 2018 Feb 5;496(2):621-627. doi: 10.1016/j.bbrc.2018.01.105.
805 The current status and future directions of myxoma virus, a master in immune evasion.Vet Res. 2011 Jun 9;42(1):76. doi: 10.1186/1297-9716-42-76.
806 Influences on plasminogen activator inhibitor-2 polymorphism-associated recurrent cardiovascular disease risk in patients with high HDL cholesterol and inflammation.Atherosclerosis. 2016 Jul;250:1-8. doi: 10.1016/j.atherosclerosis.2016.04.017. Epub 2016 Apr 21.
807 Association of asymptomatic target organ damage with secreted frizzled related protein 5 in the elderly: the Northern Shanghai Study.Clin Interv Aging. 2018 Mar 6;13:389-395. doi: 10.2147/CIA.S155514. eCollection 2018.
808 Cholesterol, lipoproteins and subclinical interstitial lung disease: the MESA study.Thorax. 2017 May;72(5):472-474. doi: 10.1136/thoraxjnl-2016-209568. Epub 2017 Jan 27.
809 Final common molecular pathways of aging and cardiovascular disease: role of the p66Shc protein.Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):622-8. doi: 10.1161/ATVBAHA.107.156059. Epub 2007 Dec 27.
810 Role of N-terminus in function and dynamics of sirtuin 7: an in silico study.J Biomol Struct Dyn. 2020 Mar;38(5):1283-1291. doi: 10.1080/07391102.2019.1600585. Epub 2019 Apr 26.
811 Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies.PLoS Genet. 2019 Sep 25;15(9):e1008208. doi: 10.1371/journal.pgen.1008208. eCollection 2019 Sep.
812 SLC35E3 identified as a target of novelm1061?p via microRNA profiling of patients with cardiovascular disease.Mol Med Rep. 2018 Apr;17(4):5159-5167. doi: 10.3892/mmr.2018.8498. Epub 2018 Jan 25.
813 Educational intervention to improve effectiveness in treatment and control of patients with high cardiovascular risk in low-resource settings in Argentina: study protocol of a cluster randomised controlled trial.BMJ Open. 2017 Jan 31;7(1):e014420. doi: 10.1136/bmjopen-2016-014420.
814 18FDG PET/CT & arterial inflammation: predicting cardiovascular events in lung cancer.QJM. 2019 Jun 1;112(6):401-407. doi: 10.1093/qjmed/hcz036.
815 Suppressor of cytokine signaling (SOCS) 2, a protein with multiple functions.Cytokine Growth Factor Rev. 2006 Dec;17(6):431-9. doi: 10.1016/j.cytogfr.2006.09.008. Epub 2006 Oct 27.
816 LR11/SorLA links triglyceride-rich lipoproteins to risk of developing cardiovascular disease in FH patients.Atherosclerosis. 2015 Dec;243(2):429-37. doi: 10.1016/j.atherosclerosis.2015.10.009. Epub 2015 Oct 13.
817 PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease.Cochrane Database Syst Rev. 2017 Apr 28;4(4):CD011748. doi: 10.1002/14651858.CD011748.pub2.
818 Relation of serum spondin-2 levels with cardiac morphology and inflammatory parameters in hemodialysis patients.Int Urol Nephrol. 2018 Nov;50(11):2091-2097. doi: 10.1007/s11255-018-1996-5. Epub 2018 Oct 1.
819 Oxidized low-density lipoprotein is a common risk factor for cardiovascular diseases and gastroenterological cancers via epigenomical regulation of microRNA-210.Oncotarget. 2015 Sep 15;6(27):24105-18. doi: 10.18632/oncotarget.4152.
820 IV-Spectrin/STAT3 complex regulates fibroblast phenotype, fibrosis, and cardiac function.JCI Insight. 2019 Oct 17;4(20):e131046. doi: 10.1172/jci.insight.131046.
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822 Concomitant Ro/SSA and La/SSB antibodies are biomarkers for the risk of venous thromboembolism and cerebral infarction in primary Sjgren's syndrome.J Intern Med. 2019 Oct;286(4):458-468. doi: 10.1111/joim.12941. Epub 2019 Jun 17.
823 Genome-Wide Inhibition of Pro-atherogenic Gene Expression by Multi-STAT Targeting Compounds as a Novel Treatment Strategy of CVDs.Front Immunol. 2018 Sep 19;9:2141. doi: 10.3389/fimmu.2018.02141. eCollection 2018.
824 STK25 Regulates Cardiovascular Disease Progression in a Mouse Model of Hypercholesterolemia.Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1723-1737. doi: 10.1161/ATVBAHA.118.311241.
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