Details of the Drug

General Information of Drug (ID: DMEG5YO)

• Drug Name: Tetra-substituted urea derivative 1
• Synonyms: PMID26413912-Compound-53
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 258.32
  Logarithm of the Partition Coefficient (xlogp); 2.8
  Rotatable Bond Count (rotbonds); 1
  Hydrogen Bond Donor Count (hbonddonor); 0
  Hydrogen Bond Acceptor Count (hbondacc); 3
• Chemical Identifiers:
  Formula: C14H18N4O
  IUPAC Name: N-cyclohexyl-N-methylbenzotriazole-1-carboxamide
  Canonical SMILES: CN(C1CCCCC1)C(=O)N2C3=CC=CC=C3N=N2
  InChI: InChI=1S/C14H18N4O/c1-17(11-7-3-2-4-8-11)14(19)18-13-10-6-5-9-12(13)15-16-18/h5-6,9-11H,2-4,7-8H2,1H3
  InChIKey: ATPCFTJMZOBYDC-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 66681741
  TTD ID: D0U0QQ

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fatty acid amide hydrolase (FAAH)	TTDP1UC	NOUNIPROTAC	Inhibitor	[1]

Molecular Expression Atlas of This Drug

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Fatty acid amide hydrolase (FAAH)	DTT	NO-GeName	2.65E-01	0.02	0.1

References

• [1] Fatty acid amide hydrolase inhibitors: a patent review (2009-2014).Expert Opin Ther Pat. 2015;25(11):1247-66.