Details of the Drug

General Information of Drug (ID: DMEIMBP)

Drug Name
AMG 811
Indication
Disease Entry ICD 11 Status REF
Discoid lupus erythematosus EB51.0 Phase 1 [1]
Systemic lupus erythematosus 4A40.0 Phase 1 [1]
Cross-matching ID
TTD ID
D06FLP
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interferon-gamma (IFNG) TT93WF5 IFNG_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028077)
2 Pharmacokinetic and pharmacodynamic relationship of AMG 811, an anti-IFN-gamma IgG1 monoclonal antibody, in patients with systemic lupus erythematosus. Pharm Res. 2015 Feb;32(2):640-53.