Details of the Drug

General Information of Drug (ID: DMEK5B2)

Drug Name

NSC-356483

Synonyms

NSC-356483; CHEMBL495563; NSC356483; AC1L7M6E; ZINC1583041; BDBM50265441; 1-(furan-2-ylmethyl)-5-(4-methoxyphenyl)triazole; 1-(furan-2-ylmethyl)-5-(4-methoxyphenyl)-1H-1,2,3-triazole

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

255.27

Logarithm of the Partition Coefficient (xlogp)

2

Rotatable Bond Count (rotbonds)

4

Hydrogen Bond Donor Count (hbonddonor)

0

Hydrogen Bond Acceptor Count (hbondacc)

4

Chemical Identifiers

Formula: C14H13N3O2
IUPAC Name: 1-(furan-2-ylmethyl)-5-(4-methoxyphenyl)triazole
Canonical SMILES: COC1=CC=C(C=C1)C2=CN=NN2CC3=CC=CO3
InChI: InChI=1S/C14H13N3O2/c1-18-12-6-4-11(5-7-12)14-9-15-16-17(14)10-13-3-2-8-19-13/h2-9H,10H2,1H3
InChIKey: LLARZMIDMIEYKJ-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 337660
TTD ID: D06GIV

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Aromatase (CYP19A1)	TTSZLWK	CP19A_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Fast three dimensional pharmacophore virtual screening of new potent non-steroid aromatase inhibitors. J Med Chem. 2009 Jan 8;52(1):143-50.