Details of the Drug

General Information of Drug (ID: DMEWAVM)

• Drug Name: 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
• Synonyms: 3-ethyl-2-(4-hydroxyphenyl)-2H-indazol-5-ol; CHEMBL180517

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 254.28
  Logarithm of the Partition Coefficient (xlogp); 3.4
  Rotatable Bond Count (rotbonds); 2
  Hydrogen Bond Donor Count (hbonddonor); 2
  Hydrogen Bond Acceptor Count (hbondacc); 3
• Chemical Identifiers:
  Formula: C15H14N2O2
  IUPAC Name: 3-ethyl-2-(4-hydroxyphenyl)indazol-5-ol
  Canonical SMILES: CCC1=C2C=C(C=CC2=NN1C3=CC=C(C=C3)O)O
  InChI: InChI=1S/C15H14N2O2/c1-2-15-13-9-12(19)7-8-14(13)16-17(15)10-3-5-11(18)6-4-10/h3-9,18-19H,2H2,1H3
  InChIKey: XBMVVMYGKMGLJX-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 11149479
  DrugBank ID: DB07712
  TTD ID: D0A8CS

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Estrogen receptor (ESR)	TTZAYWL	ESR1_HUMAN	Inhibitor	[1]

References

• [1] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.