Details of the Drug

General Information of Drug (ID: DMF27BS)

Drug Name

MMV00/0053

Synonyms

PfENR inhibitors, Jacobus; Plasmodium falciparum enoyl acyl carrier protein reductase inhibitors, Jacobus; FAS II inhibitors, Jacobus/MMV; Fatty acid biosynthesis II inhibitors, Jacobus/MMV

Indication

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Terminated	[1]
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Structure

3D Structure is Not Available

3D MOL

2D MOL

Cross-matching ID

TTD ID: D0K1UD

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Fatty acid synthetase I (Bact inhA)	TTVTX4N	INHA_MYCTU	Inhibitor	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Annual report of Medicines for Malaria Venture in 2002.
2	SAR and pharmacophore models for the rhodanine inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase. IUBMB Life. 2010 Mar;62(3):204-13.