Details of the Drug

General Information of Drug (ID: DMF3GM2)

Drug Name
Somatropin recombinant
Synonyms Genotropin (TN); Humatrope (TN); Norditropin (TN); Nutropin (TN); Saizen (TN)
Indication
Disease Entry ICD 11 Status REF
Fetal growth restriction KA20.1Z Approved [1]
Growth hormone deficiency 5A61.3 Approved [2]
Pituitary dwarfism N.A. Approved [3]
Turner syndrome N.A. Approved [4]
Therapeutic Class
Hormone Replacement Agents
Cross-matching ID
PubChem CID
16132356
TTD ID
D0P4DJ
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Growth hormone receptor (GHR) TTKMAZ6 GHR_HUMAN Binder [5]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Diagnosis and management of Silver-Russell syndrome: first international consensus statement. Nat Rev Endocrinol. 2017 Feb;13(2):105-124.
2 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
3 Efficacy and Safety of Weekly Somatrogon vs Daily Somatropin in Children With Growth Hormone Deficiency: A Phase 3 Study. J Clin Endocrinol Metab. 2022 Jun 16;107(7):e2717-e2728.
4 The use of somatropin (recombinant growth hormone) in children of short stature. Paediatr Drugs. 2002;4(1):37-47.
5 Cost-utility of somatropin (rDNA origin) in the treatment of growth hormone deficiency in children. Curr Med Res Opin. 2006 Feb;22(2):351-7.