Details of Disease

General Information of Disease (ID: DIS5WEJ5)

Disease Name Fetal growth restriction
Synonyms
intrauterine Growth retardation; fetal SGA; fetal Growth retardation; foetal SGA; foetus small for gestational Age; foetal growth retardation; intrauterine Growth restriction; IUGR; foetal small for gestational Age; fetus small for gestational Age; foetal Growth retardation; fetal growth retardation; fetal small for gestational Age
Disease Class KA20: Newborn related slow foetal growth/foetal malnutrition disorder
Definition A fetus that does not grow beyond the 10th percentile of conventionally accepted weight for gestational age.|Editor note: check if should be a disease
Disease Hierarchy
DISUW4CP: Placenta disorder
DIS5WEJ5: Fetal growth restriction
ICD Code
ICD-11
ICD-11: KA20.1Z
Expand ICD-11
'KA20.1Z
Disease Identifiers
MONDO ID
MONDO_0005030
MESH ID
D005317
UMLS CUI
C0015934
MedGen ID
4693
HPO ID
HP:0001511
SNOMED CT ID
22033007

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 1 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Somatropin recombinant DMF3GM2 Approved NA [1]
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This Disease is Treated as An Indication in 1 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
EG-013 DM27LJQ Investigative NA [2]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 118 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ABCB1 TT3OT40 Limited Biomarker [3]
ARG1 TT7ZQEV Limited Biomarker [4]
BMP4 TTD3BSX Limited Biomarker [5]
CAD TT2YT1K Limited Biomarker [6]
CDKN1C TTBSUAR Limited Altered Expression [7]
CPS1 TT42M75 Limited Biomarker [6]
CYP11A1 TTSYVO6 Limited Biomarker [8]
CYP11B1 TTIQUX7 Limited Biomarker [9]
DLK1 TTF4AVB Limited Biomarker [10]
DNMT3B TT6VZ78 Limited Biomarker [11]
DRD4 TTE0A2F Limited Genetic Variation [12]
DUSP1 TTG8HIM Limited Biomarker [13]
DUSP5 TTZN92A Limited Biomarker [14]
G6PC TTBQMJ8 Limited Biomarker [15]
GAP43 TTSGLN5 Limited Altered Expression [16]
GHRL TT1OCL0 Limited ModifyingMutation [17]
GHSR TTWDC17 Limited ModifyingMutation [17]
GRIA1 TTVPQTF Limited Biomarker [18]
GRIN2A TTKJEMQ Limited Biomarker [18]
GRIN2B TTN9D8E Limited Therapeutic [19]
HDAC1 TT6R7JZ Limited Biomarker [11]
HDAC2 TTSHTOI Limited Biomarker [11]
IRS2 TTF95B8 Limited Biomarker [20]
KCNA5 TTW0CMT Limited Altered Expression [21]
MDM2 TT9TE0O Limited Biomarker [22]
MECP2 TTTAU9R Limited Biomarker [23]
MTM1 TTY2TCU Limited Biomarker [24]
MUC1 TTBHFYQ Limited Biomarker [25]
NOS1 TTZUFI5 Limited Biomarker [26]
OTC TT5KIO9 Limited Biomarker [27]
PTGER3 TTPNGDE Limited Biomarker [28]
PTPN11 TT7WUAV Limited Therapeutic [29]
SLC15A1 TT5LF3C Limited Biomarker [30]
SLC2A12 TTZO36H Limited Altered Expression [31]
SLC38A4 TTJE54U Limited Genetic Variation [32]
SOD1 TTP9K3Q Limited Biomarker [33]
SREBF1 TTER0UB Limited Biomarker [34]
STAR TTEI40H Limited Biomarker [8]
TPH1 TTZSJHV Limited Altered Expression [35]
TPH2 TT3KLDP Limited Altered Expression [35]
CYP17A1 TTRA5BZ Disputed Genetic Variation [36]
ABCG1 TTMWDGU moderate Altered Expression [37]
ADIPOQ TTXKA7D moderate Biomarker [38]
ADM2 TTM642F moderate Biomarker [39]
AGTR1 TT8DBY3 moderate Altered Expression [40]
APOH TT2OUI9 moderate Biomarker [41]
ARG2 TTV1AG6 moderate Biomarker [42]
ATP1A1 TTWK8D0 moderate Altered Expression [43]
C1QBP TTWTD7F moderate Altered Expression [44]
C5 TTKANGO moderate Biomarker [45]
CALCRL TTY6O0Q moderate Biomarker [39]
CASP3 TTPF2QI moderate Biomarker [46]
CNP TT71P0H moderate Altered Expression [47]
COMT TTKWFB8 moderate Genetic Variation [12]
DUSP9 TT1GV6C moderate Altered Expression [48]
FCGR1A TTZK4I3 moderate Biomarker [49]
GFAP TTI6FFX moderate Biomarker [50]
GLRX TTRJCNG moderate Altered Expression [51]
GOT1 TTU507L moderate Biomarker [52]
HSD17B1 TTIWB6L moderate Altered Expression [53]
IGF1R TTQFBMY moderate Genetic Variation [54]
INHBA TTVB30D moderate Altered Expression [55]
KCNK3 TTGR91N moderate Biomarker [56]
LGALS2 TTRHK90 moderate Altered Expression [57]
LGR4 TTY6C71 moderate Biomarker [58]
LIPG TTHSZXO moderate Biomarker [59]
MAG TT9XFON moderate Biomarker [60]
NFE2L2 TTA6ZN2 moderate Biomarker [61]
NR3C1 TTOZRK6 moderate Altered Expression [62]
NTF4 TTIM2WO moderate Genetic Variation [63]
OGDH TTH8T6I moderate Biomarker [64]
PFKFB2 TTQYVKD moderate Altered Expression [64]
PROKR1 TTB9CIL moderate Biomarker [65]
PROKR2 TTM67AX moderate Altered Expression [65]
SLC2A1 TT79TKF moderate Biomarker [66]
SMYD3 TTKLJYX moderate Altered Expression [67]
SYVN1 TT8XKYM moderate Biomarker [68]
TACR3 TTBPGLU moderate Genetic Variation [69]
TDO2 TTXNCBV moderate Altered Expression [70]
UCP3 TT12RJK moderate Altered Expression [71]
AFP TTCFEA1 Strong Biomarker [72]
AGT TT5C0UB Strong Altered Expression [40]
AGTR2 TTQVOEI Strong Biomarker [73]
AIF1 TT12MEP Strong Biomarker [74]
ANG TTURHFP Strong Biomarker [75]
BAX TTQ57WJ Strong Altered Expression [76]
CTH TTLQUZS Strong Biomarker [77]
CUL7 TTI8R0P Strong Altered Expression [78]
DCN TTB3XAN Strong Altered Expression [79]
DNMT1 TT6S2FE Strong Altered Expression [16]
EIF2AK3 TT79U1M Strong Biomarker [80]
FSTL3 TTWRPM8 Strong Biomarker [81]
GCK TTDLNGZ Strong Genetic Variation [82]
GH1 TTT3YKH Strong Biomarker [83]
GLI2 TT045OH Strong Genetic Variation [84]
HMGA2 TTSTVM0 Strong Biomarker [85]
HSD11B2 TT9H85R Strong Altered Expression [86]
IGFBP3 TTZHNQA Strong Altered Expression [87]
INSR TTCBFJO Strong Altered Expression [71]
IRS1 TTAJSQ0 Strong Biomarker [88]
MAPK1 TT4TQBX Strong Biomarker [89]
NOD1 TTYSRXM Strong Altered Expression [90]
NPPC TTRK0B9 Strong Biomarker [91]
PAH TTGSVH2 Strong Biomarker [92]
PDK1 TTCZOF2 Strong Biomarker [93]
PDX1 TT8SGZK Strong Altered Expression [94]
PGF TT48I1Y Strong Altered Expression [95]
PLAC1 TTM18HX Strong Altered Expression [96]
POR TTOQ9GZ Strong Biomarker [97]
REN TTB2MXP Strong Biomarker [98]
SLC38A2 TTUSC27 Strong Altered Expression [99]
SLC7A1 TT4S150 Strong Altered Expression [100]
TBXA2R TT2O84V Strong Biomarker [101]
ACE2 TTUI5H7 Definitive Biomarker [40]
ESRRG TT9ZRHB Definitive Biomarker [102]
FGR TTPOGS1 Definitive Genetic Variation [103]
IGF2 TTE8WGO Definitive Posttranslational Modification [104]
SLC2A4 TTP6MT5 Definitive Biomarker [66]
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⏷ Show the Full List of 118 DTT(s)
This Disease Is Related to 13 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
ABCC6 DT582KR Limited Biomarker [105]
SLC16A7 DTLT3UG Limited Altered Expression [106]
SLC27A6 DTG4CWJ Limited Altered Expression [107]
SLC2A2 DTUJPOL Limited Biomarker [108]
SLC2A8 DT2I7BM Limited Altered Expression [31]
SLC1A4 DTC54PX moderate Altered Expression [109]
SLC27A1 DTKDTML moderate Altered Expression [110]
SLC35A1 DTVZIRG moderate Biomarker [111]
SLC43A2 DTK02I1 moderate Biomarker [112]
SLC5A3 DT8ACN1 moderate Altered Expression [113]
SLC6A6 DTHWCVA moderate Biomarker [114]
SLC20A2 DTFD4VB Strong Biomarker [115]
SLC2A3 DT9SQ3L Strong Altered Expression [116]
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⏷ Show the Full List of 13 DTP(s)
This Disease Is Related to 12 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
PCK1 DEPLH5Z Limited Biomarker [117]
ASNS DEXISVQ moderate Biomarker [118]
CPA4 DEXKD7J moderate Altered Expression [119]
DDAH1 DEY0TQC moderate Altered Expression [42]
GALK1 DE3OP9S moderate Biomarker [71]
LDHC DEQG7F9 moderate Altered Expression [64]
MAT1A DEQ6NC9 moderate Biomarker [120]
PON2 DEHJU7E moderate Altered Expression [121]
PON3 DETXQZ1 moderate Altered Expression [121]
UGDH DE48Q2Z moderate Altered Expression [122]
CYP1A1 DE6OQ3W Strong Altered Expression [123]
CYP7A1 DEDZRQ1 Strong Biomarker [124]
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⏷ Show the Full List of 12 DME(s)
This Disease Is Related to 150 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ACE OTDF1964 Limited Biomarker [40]
ACTA1 OTOVGLPG Limited Biomarker [125]
ACTA2 OTEDLG8E Limited Biomarker [77]
ADIPOR1 OT65ZFZN Limited Therapeutic [126]
ADIPOR2 OT2HDTL8 Limited Therapeutic [126]
AFM OTPOR8IO Limited Biomarker [127]
ALDH3A1 OTAYZZE6 Limited Altered Expression [128]
ARNT OTMSIEZY Limited Biomarker [129]
ASPRV1 OT8WVIBW Limited Altered Expression [130]
ATP2B2 OT1NPZ9T Limited Biomarker [131]
ATP2B3 OT9DIEOP Limited Biomarker [131]
ATP5F1A OT3FZDLX Limited Biomarker [132]
ATP5F1B OTLFZUQK Limited Biomarker [133]
ATP6 OTPHOGLX Limited Biomarker [93]
CALD1 OTNJKJ6Q Limited Altered Expression [134]
CARD8 OTXXZYWU Limited Biomarker [135]
CENPV OTPQ0KT9 Limited Biomarker [136]
COL2A1 OT5E59C8 Limited Biomarker [88]
CSH1 OT33HTRR Limited Biomarker [137]
CSH2 OTW8JVAN Limited Biomarker [137]
DES OTI09KBW Limited Biomarker [77]
DLX5 OTEEFBEU Limited Altered Expression [138]
ERN2 OTUS6GKR Limited Altered Expression [139]
FABP7 OTRE2H4G Limited Altered Expression [140]
FCN3 OTPRENLS Limited Biomarker [141]
GDF9 OTNTVKVU Limited Altered Expression [142]
HAS2 OTTD3PAL Limited Altered Expression [143]
HMGB3 OTCJ2EZY Limited Altered Expression [144]
HOXB7 OTC7WYU8 Limited Altered Expression [145]
HRG OTPLUFOG Limited Altered Expression [146]
IHH OT1DWGXC Limited Genetic Variation [147]
MAPK6 OTDDNF3Q Limited Genetic Variation [148]
MASP1 OTWWCNZP Limited Biomarker [141]
MUC4 OTLT11V1 Limited Biomarker [25]
ND6 OTG47B7B Limited Biomarker [93]
OIP5 OTI5C2DE Limited Biomarker [149]
PAK3 OT80M3BV Limited Biomarker [105]
PBX1 OTORABGO Limited Genetic Variation [150]
PDP1 OT82RTMT Limited Altered Expression [151]
PEX14 OT98BZHE Limited Altered Expression [152]
PLIN2 OTRXJ9UN Limited Biomarker [107]
PPARGC1A OTHCDQ22 Limited Biomarker [153]
RARRES1 OTETUPP5 Limited Altered Expression [154]
RBP1 OTRP1MFC Limited Biomarker [77]
SIN3A OTM8OZWV Limited Biomarker [155]
TFF3 OTJJDRTU Limited Biomarker [25]
ACP1 OTJ9CKLU moderate Genetic Variation [156]
AHSP OTTHBSUS moderate Altered Expression [157]
ATG14 OTPZDKI0 moderate Altered Expression [158]
ATL1 OTR2788Y moderate Biomarker [159]
BCKDHA OT0LHOZB moderate Biomarker [160]
BCL11B OT8KKCVJ moderate Biomarker [159]
BCS1L OT5PY5CY moderate Biomarker [161]
BHMT OTYB6PXZ moderate Altered Expression [162]
CD8A OTDWQJXK moderate Altered Expression [44]
CDCA5 OTZLCQ5U moderate Biomarker [163]
CITED1 OTUJQ3VL moderate Biomarker [164]
CLIC3 OT5KUZ3A moderate Biomarker [165]
COX4I1 OTU0FC24 moderate Biomarker [166]
CPT2 OTIN6G20 moderate Altered Expression [167]
CPXM2 OTDJNOTR moderate Altered Expression [168]
CRYL1 OT0SJSJM moderate Altered Expression [122]
CYFIP1 OTOBEH24 moderate Biomarker [169]
DLAT OT9LBJVN moderate Altered Expression [64]
DLX4 OTLWVCN4 moderate Biomarker [170]
DNAJB9 OT38EQT6 moderate Biomarker [118]
ELF5 OTLRU8YF moderate Altered Expression [171]
EMP2 OTPS2H0L moderate Biomarker [172]
ERVFRD-1 OT3064D7 moderate Altered Expression [109]
ERVW-1 OTWV8DXJ moderate Biomarker [173]
GAL3ST1 OTSFFZRD moderate Biomarker [111]
GCHFR OTEOT8GI moderate Biomarker [163]
H6PD OTO7TNDD moderate Altered Expression [122]
HLX OT7DTH46 moderate Altered Expression [7]
HSPBP1 OTRS37HK moderate Biomarker [174]
IFT80 OTMH0MBI moderate Altered Expression [67]
ING2 OT6H0EWF moderate Altered Expression [44]
INHA OT7HWCO3 moderate Biomarker [175]
INSL4 OTK9F0LX moderate Altered Expression [176]
KLRB1 OTQ2959Y moderate Genetic Variation [69]
LAMA1 OTQZMP86 moderate Biomarker [115]
LAMA4 OTHI7TA0 moderate Biomarker [177]
LBX1 OTQJHICM moderate Altered Expression [65]
LGALS13 OTEV3DD7 moderate Genetic Variation [178]
LRP8 OTZ71YV2 moderate Biomarker [179]
LRRC15 OTX7JL8H moderate Genetic Variation [173]
MEST OT8Q4U8Y moderate Altered Expression [55]
MFSD2A OTVG1VG0 moderate Altered Expression [109]
NFAT5 OTKIE59S moderate Altered Expression [113]
NFIA OTDHQ9CG moderate Genetic Variation [180]
NIPA1 OT9ODC8X moderate Biomarker [169]
PAX7 OTDMQRPO moderate Biomarker [181]
PDHX OTG7O271 moderate Altered Expression [94]
PKD2 OTIXBU8H moderate Altered Expression [67]
PPP4R1 OTNGSWTU moderate Altered Expression [182]
PSG5 OTHTU98X moderate Genetic Variation [183]
RAB3A OT2GIUO5 moderate Altered Expression [94]
RAMP1 OT7UT2XB moderate Altered Expression [39]
RAMP2 OTGQXLH5 moderate Altered Expression [39]
RAMP3 OTX6XLLM moderate Altered Expression [39]
RCAN1 OT1MVXC7 moderate Altered Expression [55]
SAMD9 OTDG48P0 moderate Genetic Variation [184]
SHOX OTE0YZJO moderate Genetic Variation [185]
STOX2 OTE9BK02 moderate Altered Expression [186]
STRA6 OT2IDF27 moderate Biomarker [187]
TMPO OTL68EL4 moderate Altered Expression [101]
TRIP11 OT4FJEAR moderate Genetic Variation [188]
ADAM12 OTZKOTDB Strong Biomarker [189]
AGA OTNWT1WB Strong Biomarker [190]
ATF6 OTAFHAVI Strong Altered Expression [139]
ATP6V0A2 OTJBDX0Y Strong Genetic Variation [191]
BUB1B OT8KME51 Strong Genetic Variation [192]
CCDC8 OTO295IH Strong Biomarker [193]
CORIN OT4SK7DK Strong Biomarker [194]
ELN OTFSO7PG Strong Biomarker [195]
FBN1 OTYCJT63 Strong Altered Expression [196]
GINS1 OTVQZMMQ Strong Biomarker [197]
GLUD1 OTXKOCUH Strong Altered Expression [122]
GPKOW OTGS3H0M Strong Biomarker [198]
GRB10 OTCKXGRC Strong Altered Expression [182]
HADHA OTO557N2 Strong Altered Expression [101]
HOXD13 OTWSC8TF Strong Biomarker [199]
MNX1 OTXP9FH1 Strong Biomarker [200]
MPI OTBH6ZK1 Strong Biomarker [201]
MRPS28 OT8CLJ6M Strong Genetic Variation [202]
MUC2 OT3X4QVX Strong Biomarker [203]
NLRP7 OTE9BI32 Strong Biomarker [204]
NSD2 OTQ6SW4R Strong Biomarker [205]
ORC1 OTHWU8IJ Strong Biomarker [206]
PAPPA OTTTG9PG Strong Altered Expression [96]
PAPPA2 OTXYGTUZ Strong Altered Expression [96]
PEG10 OTWD2278 Strong Altered Expression [207]
PHLDA2 OTMV9DPP Strong Biomarker [208]
PIGF OTJKE6VW Strong Genetic Variation [209]
PLAG1 OTT9AJQY Strong Biomarker [85]
PLAGL1 OTZAO900 Strong Altered Expression [210]
POTEF OTV3WXYE Strong Altered Expression [211]
PTX3 OTPXHRKU Strong Altered Expression [212]
RB1 OT9VMY7B Strong Altered Expression [7]
RTL1 OTOT33IM Strong Posttranslational Modification [213]
SERPINB2 OT72QLZB Strong Altered Expression [214]
SESN2 OT889IXY Strong Biomarker [215]
SMC3 OTWGFRHD Strong Biomarker [216]
SRY OT516T6D Strong Genetic Variation [217]
TBCE OTGBSTKS Strong Genetic Variation [68]
TGIF1 OTN9VHAG Strong Altered Expression [218]
DLX3 OTARP5SQ Definitive Altered Expression [70]
FBXW8 OTJG15EO Definitive Altered Expression [78]
OCLN OTSUTVWL Definitive Biomarker [61]
PEG3 OTHQW98S Definitive Biomarker [219]
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⏷ Show the Full List of 150 DOT(s)

References

1 Diagnosis and management of Silver-Russell syndrome: first international consensus statement. Nat Rev Endocrinol. 2017 Feb;13(2):105-124.
2 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
3 Alterations of placental cytochrome P450 1A1 and P-glycoprotein in tobacco-induced intrauterine growth retardation in rats.Acta Pharmacol Sin. 2005 Nov;26(11):1387-94. doi: 10.1111/j.1745-7254.2005.00209.x.
4 Arginase upregulation and eNOS uncoupling contribute to impaired endothelium-dependent vasodilation in a rat model of intrauterine growth restriction.Am J Physiol Regul Integr Comp Physiol. 2018 Sep 1;315(3):R509-R520. doi: 10.1152/ajpregu.00354.2017. Epub 2018 May 9.
5 Delayed myelination in an intrauterine growth retardation model is mediated by oxidative stress upregulating bone morphogenetic protein 4.J Neuropathol Exp Neurol. 2012 Jul;71(7):640-53. doi: 10.1097/NEN.0b013e31825cfa81.
6 [Ammonia metabolism of liver of the fetus induced experimental IUGR in rats--in respect of the enzymes in pyrimidin biosynthesis and urea cycle system].Nihon Sanka Fujinka Gakkai Zasshi. 1985 Jan;37(1):24-30.
7 Expression of Homeobox Gene HLX and its Downstream Target Genes are Altered in Placentae From Discordant Twin Pregnancies.Twin Res Hum Genet. 2018 Feb;21(1):42-50. doi: 10.1017/thg.2017.66. Epub 2017 Dec 7.
8 Nicotine-induced prenatal overexposure to maternal glucocorticoid and intrauterine growth retardation in rat.Exp Toxicol Pathol. 2007 Nov;59(3-4):245-51. doi: 10.1016/j.etp.2007.05.007. Epub 2007 Sep 19.
9 Fetal adrenal gland alterations in a rat model of adverse intrauterine environment.Am J Physiol Regul Integr Comp Physiol. 2010 Apr;298(4):R899-911. doi: 10.1152/ajpregu.00238.2009. Epub 2009 Nov 18.
10 Fetus-derived DLK1 is required for maternal metabolic adaptations to pregnancy and is associated with fetal growth restriction.Nat Genet. 2016 Dec;48(12):1473-1480. doi: 10.1038/ng.3699. Epub 2016 Oct 24.
11 Prenatal caffeine ingestion induces aberrant DNA methylation and histone acetylation of steroidogenic factor 1 and inhibits fetal adrenal steroidogenesis.Toxicology. 2014 Jul 3;321:53-61. doi: 10.1016/j.tox.2014.03.011. Epub 2014 Apr 6.
12 Fetal growth interacts with multilocus genetic score reflecting dopamine signaling capacity to predict spontaneous sugar intake inchildren.Appetite. 2018 Jan 1;120:596-601. doi: 10.1016/j.appet.2017.10.021. Epub 2017 Oct 14.
13 [Effect of traditional Chinese medicine on expression of extracellular signal-regulating kinase-1 and mitogen activated protein kinase phosphatase-1 in brain and liver of fetal rats with fetal growth restriction].Zhonghua Fu Chan Ke Za Zhi. 2002 Nov;37(11):672-5.
14 Growth retardation alters the epigenetic characteristics of hepatic dual specificity phosphatase 5.FASEB J. 2006 Oct;20(12):2127-9. doi: 10.1096/fj.06-6179fje. Epub 2006 Aug 29.
15 Enhanced trimethylation of histone h3 mediates impaired expression of hepatic glucose 6-phosphatase expression in offspring from rat dams exposed to hypoxia during pregnancy.Reprod Sci. 2014 Jan;21(1):112-21. doi: 10.1177/1933719113492212. Epub 2013 Jun 6.
16 Effects of Folic Acid on DNMT1, GAP43, and VEGFR1 in Intrauterine Growth Restriction Filial Rats.Reprod Sci. 2018 Mar;25(3):366-371. doi: 10.1177/1933719117715128. Epub 2017 Jun 22.
17 [Relationship between Ghrelin and growth hormone secretagogue receptor expression and catch-up growth in rats with intrauterine growth restriction].Zhongguo Dang Dai Er Ke Za Zhi. 2010 Jul;12(7):563-8.
18 Cortical neurons from intrauterine growth retardation rats exhibit lower response to neurotrophin BDNF.Neurosci Lett. 2010 May 31;476(2):104-9. doi: 10.1016/j.neulet.2010.03.082. Epub 2010 Apr 14.
19 [Effect of behavioral training on learning and memory capacity and changes of hippocampal NR2B and GluR1 expressions in FGR offspring rats].Nan Fang Yi Ke Da Xue Xue Bao. 2010 Apr;30(4):708-11.
20 Assessment of the expression of IR, IRS-1, IRS-2 and IGF-IR in a rat model of intrauterine growth restriction.Fetal Diagn Ther. 2010;28(3):145-52. doi: 10.1159/000316932. Epub 2010 Aug 19.
21 Increased Expression of MicroRNA-206 Inhibits Potassium Voltage-Gated Channel Subfamily A Member 5 in Pulmonary Arterial Smooth Muscle Cells and Is Related to Exaggerated Pulmonary Artery Hypertension Following Intrauterine Growth Retardation in Rats.J Am Heart Assoc. 2019 Jan 22;8(2):e010456. doi: 10.1161/JAHA.118.010456.
22 Nonresponsiveness of cerebral p53-MDM2 functional circuit in newborn rat pups rendered IUGR via uteroplacental insufficiency.Am J Physiol Regul Integr Comp Physiol. 2005 Apr;288(4):R1038-45. doi: 10.1152/ajpregu.00701.2004. Epub 2004 Nov 24.
23 Uteroplacental insufficiency affects epigenetic determinants of chromatin structure in brains of neonatal and juvenile IUGR rats.Physiol Genomics. 2006 Mar 13;25(1):16-28. doi: 10.1152/physiolgenomics.00093.2005. Epub 2005 Dec 27.
24 Preterm Preeclampsia with Severe Features: Composite Maternal and Neonatal Morbidities Associated with Fetal Growth Restriction.Am J Perinatol. 2018 Jul;35(8):785-790. doi: 10.1055/s-0037-1617456. Epub 2018 Jan 3.
25 Intrauterine growth restriction alters postnatal colonic barrier maturation in rats.Pediatr Res. 2009 Jul;66(1):47-52. doi: 10.1203/PDR.0b013e3181a2047e.
26 Intrauterine growth restriction and shallower implantation site in rats with maternal hyperinsulinemia are associated with altered NOS expression.Placenta. 2009 Oct;30(10):898-906. doi: 10.1016/j.placenta.2009.07.014. Epub 2009 Aug 25.
27 Altered hepatic gene expression of enzymes involved in energy metabolism in the growth-retarded fetal rat.Pediatr Res. 1996 Mar;39(3):390-4. doi: 10.1203/00006450-199603000-00003.
28 Elevation of both cyclooxygenase-2 and prostaglandin E2 receptor EP3 expressions in rat placenta after uterine artery ischemia-reperfusion.Placenta. 2006 Apr-May;27(4-5):395-401. doi: 10.1016/j.placenta.2005.04.007. Epub 2005 Jun 28.
29 Peroxisome proliferator-activated receptor-gamma agonist improves skeletal muscle insulin signaling in the pregestational intrauterine growth-restricted rat offspring.Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E514-24. doi: 10.1152/ajpendo.00008.2009. Epub 2009 Jun 2.
30 N-Carbamylglutamate and l-Arginine Promote Intestinal Absorption of Amino Acids by Regulating the mTOR Signaling Pathway and Amino Acid and Peptide Transporters in Suckling Lambs with Intrauterine Growth Restriction.J Nutr. 2019 Jun 1;149(6):923-932. doi: 10.1093/jn/nxz016.
31 Humanin (HN) and glucose transporter 8 (GLUT8) in pregnancies complicated by intrauterine growth restriction.PLoS One. 2018 Mar 28;13(3):e0193583. doi: 10.1371/journal.pone.0193583. eCollection 2018.
32 Paternal knockout of Slc38a4/SNAT4 causes placental hypoplasia associated with intrauterine growth restriction in mice.Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21047-21053. doi: 10.1073/pnas.1907884116. Epub 2019 Sep 30.
33 Changes in pro/antioxidant balance in smoking and non-smoking pregnant women with intrauterine growth restriction.Reprod Toxicol. 2011 Nov;32(3):360-7. doi: 10.1016/j.reprotox.2011.08.007. Epub 2011 Aug 26.
34 Programmed upregulation of adipogenic transcription factors in intrauterine growth-restricted offspring.Reprod Sci. 2008 Oct;15(8):785-96. doi: 10.1177/1933719108318597.
35 Disrupted placental serotonin synthetic pathway and increased placental serotonin: Potential implications in the pathogenesis of human fetal growth restriction.Placenta. 2019 Sep 1;84:74-83. doi: 10.1016/j.placenta.2019.05.012. Epub 2019 May 23.
36 Genetic polymorphism of catechol-O-methyltransferase and cytochrome P450c17 in preeclampsia.Pharmacogenet Genomics. 2010 Oct;20(10):605-10. doi: 10.1097/FPC.0b013e32833df033.
37 Placental ABCA1 and ABCG1 expression in gestational disease: Pre-eclampsia affects ABCA1 levels in syncytiotrophoblasts.Placenta. 2013 Nov;34(11):1079-86. doi: 10.1016/j.placenta.2013.06.309. Epub 2013 Jul 20.
38 Adiponectin concentration in mid-trimester amniotic fluid varies with the -amylase level and maternal and neonatal outcomes.J Perinat Med. 2018 Apr 25;46(3):317-321. doi: 10.1515/jpm-2017-0094.
39 Impaired Vasodilatory Responses of Omental Arteries to CGRP Family Peptides in Pregnancies Complicated by Fetal Growth Restriction.J Clin Endocrinol Metab. 2016 Aug;101(8):2984-93. doi: 10.1210/jc.2016-1798. Epub 2016 Jun 3.
40 Dysregulation of the placental renin-angiotensin system in human fetal growth restriction.Reproduction. 2019 Sep;158(3):237-245. doi: 10.1530/REP-18-0633.
41 Antiphospholipid antibody profile based obstetric outcomesof primary antiphospholipid syndrome: thePREGNANTS study.Am J Obstet Gynecol. 2017 May;216(5):525.e1-525.e12. doi: 10.1016/j.ajog.2017.01.026. Epub 2017 Jan 30.
42 Arginine bioavailability and endothelin-1 system in the regulation of vascular function of umbilical vein endothelial cells from intrauterine growth restricted newborns.Nutr Metab Cardiovasc Dis. 2018 Dec;28(12):1285-1295. doi: 10.1016/j.numecd.2018.09.002. Epub 2018 Sep 22.
43 Activity and protein expression of Na+/K+ ATPase are reduced in microvillous syncytiotrophoblast plasma membranes isolated from pregnancies complicated by intrauterine growth restriction.J Clin Endocrinol Metab. 2003 Jun;88(6):2831-7. doi: 10.1210/jc.2002-021926.
44 A role for the mitochondrial-associated protein p32 in regulation of trophoblast proliferation.Mol Hum Reprod. 2014 Aug;20(8):745-55. doi: 10.1093/molehr/gau039. Epub 2014 May 29.
45 Unilateral uterine ischemia/reperfusion-induced bilateral fetal loss and fetal growth restriction in a murine model require intact complement component 5.J Reprod Immunol. 2012 Sep;95(1-2):27-35. doi: 10.1016/j.jri.2012.04.005. Epub 2012 Jun 9.
46 Severe Uncontrolled Maternal Hyperglycemia Induces Microsomia and Neurodevelopment Delay Accompanied by Apoptosis, Cellular Survival, and Neuroinflammatory Deregulation in Rat Offspring Hippocampus.Cell Mol Neurobiol. 2019 Apr;39(3):401-414. doi: 10.1007/s10571-019-00658-8. Epub 2019 Feb 9.
47 Expression of C-type natriuretic peptide in human placenta and myometrium in normal pregnancies and pregnancies complicated by intrauterine growth retardation. Preliminary results.Fetal Diagn Ther. 2002 Jan-Feb;17(1):37-41. doi: 10.1159/000048004.
48 Dual specificity phosphatase 9 (DUSP9) expression is down-regulated in the severe pre-eclamptic placenta.Placenta. 2013 Feb;34(2):174-81. doi: 10.1016/j.placenta.2012.11.029. Epub 2012 Dec 29.
49 The insulin-like growth factor system and fetal growth restrictionn.Pediatr Endocrinol Rev. 2008 Dec;6(2):235-40.
50 Murine maternal dietary restriction affects neural Humanin expression and cellular profile.J Neurosci Res. 2020 May;98(5):902-920. doi: 10.1002/jnr.24568. Epub 2019 Dec 15.
51 Decreased expression of thioredoxin and glutaredoxin in placentae from pregnancies with pre-eclampsia and intrauterine growth restriction.Placenta. 2000 Sep;21(7):603-9. doi: 10.1053/plac.2000.0554.
52 Maternal placenta modulates a deleterious fetal mutation.Biol Reprod. 2017 Aug 1;97(2):249-257. doi: 10.1093/biolre/iox064.
53 Estrogen-related receptor regulates expression of 17-hydroxysteroid dehydrogenase type 1 in fetal growth restriction.Placenta. 2018 Jul;67:38-44. doi: 10.1016/j.placenta.2018.05.012. Epub 2018 May 29.
54 A new p.(Ile66Serfs*93) IGF2 variant is associated with pre- and postnatal growth retardation.Eur J Endocrinol. 2019 Jan 1;180(1):K1-K13. doi: 10.1530/EJE-18-0601.
55 Unbalanced placental expression of imprinted genes in human intrauterine growth restriction.Placenta. 2006 Jun-Jul;27(6-7):540-9. doi: 10.1016/j.placenta.2005.07.004. Epub 2005 Aug 24.
56 Differential expression of potassium channels in placentas from normal and pathological pregnancies: targeting of the K(ir) 2.1 channel to lipid rafts.J Membr Biol. 2012 Mar;245(3):141-50. doi: 10.1007/s00232-012-9422-x. Epub 2012 Mar 4.
57 Placental Expression Patterns of Galectin-1, Galectin-2, Galectin-3 and Galectin-13 in Cases of Intrauterine Growth Restriction (IUGR).Int J Mol Sci. 2016 Apr 7;17(4):523. doi: 10.3390/ijms17040523.
58 Leucine-rich repeat-containing, G protein-coupled receptor 4 null mice exhibit intrauterine growth retardation associated with embryonic and perinatal lethality.Mol Endocrinol. 2004 Sep;18(9):2241-54. doi: 10.1210/me.2004-0133. Epub 2004 Jun 10.
59 Dysregulation of placental endothelial lipase and lipoprotein lipase in intrauterine growth-restricted pregnancies.J Clin Endocrinol Metab. 2007 Jun;92(6):2256-63. doi: 10.1210/jc.2006-2403. Epub 2007 Mar 13.
60 The extent of intrauterine growth restriction determines the severity of cerebral injury and neurobehavioural deficits in rodents.PLoS One. 2017 Sep 21;12(9):e0184653. doi: 10.1371/journal.pone.0184653. eCollection 2017.
61 N-carbamylglutamate and l-arginine promote intestinal function in suckling lambs with intrauterine growth restriction by regulating antioxidant capacity via a nitric oxide-dependent pathway.Food Funct. 2019 Oct 16;10(10):6374-6384. doi: 10.1039/c9fo01752f.
62 Glucocorticoid receptors and are modulated sex specifically in human placentas of intrauterine growth restriction (IUGR).Arch Gynecol Obstet. 2019 Aug;300(2):323-335. doi: 10.1007/s00404-019-05189-7. Epub 2019 May 14.
63 Antecedents and correlates of blood concentrations of neurotrophic growth factors in very preterm newborns.Cytokine. 2017 Jun;94:21-28. doi: 10.1016/j.cyto.2017.03.012. Epub 2017 Apr 7.
64 Placental gene expression is related to glucose metabolism and fetal cord blood levels of insulin and insulin-like growth factors in intrauterine growth restriction.Early Hum Dev. 2010 Jan;86(1):45-50. doi: 10.1016/j.earlhumdev.2010.01.001. Epub 2010 Jan 27.
65 EG-VEGF controls placental growth and survival in normal and pathological pregnancies: case of fetal growth restriction (FGR).Cell Mol Life Sci. 2013 Feb;70(3):511-25. doi: 10.1007/s00018-012-1141-z. Epub 2012 Sep 2.
66 Postnatal 2 adrenergic treatment improves insulin sensitivity in lambs with IUGR but not persistent defects in pancreatic islets or skeletal muscle.J Physiol. 2019 Dec;597(24):5835-5858. doi: 10.1113/JP278726. Epub 2019 Nov 29.
67 iTRAQ-Based Proteomic Analysis of Neonatal Kidney from Offspring of Protein Restricted Rats Reveals Abnormalities in Intraflagellar Transport Proteins.Cell Physiol Biochem. 2017;44(1):185-199. doi: 10.1159/000484626. Epub 2017 Nov 6.
68 Ophthalmic features of hypoparathyroidism-retardation-dysmorphism.J AAPOS. 2007 Jun;11(3):288-90. doi: 10.1016/j.jaapos.2006.10.015. Epub 2007 Jan 25.
69 How does variability of immune system genes affect placentation?.Placenta. 2011 Aug;32(8):539-45. doi: 10.1016/j.placenta.2011.05.001. Epub 2011 Jun 12.
70 Altered placental tryptophan metabolic pathway in human fetal growth restriction.Placenta. 2017 Apr;52:62-70. doi: 10.1016/j.placenta.2017.02.013. Epub 2017 Feb 16.
71 Alterations in the liver of intrauterine growth retarded piglets may predispose to development of insulin resistance and obesity in later life.J Physiol Pharmacol. 2018 Apr;69(2). doi: 10.26402/jpp.2018.2.06. Epub 2018 Jun 13.
72 Assessing the role of placental trisomy in preeclampsia and intrauterine growth restriction.Prenat Diagn. 2010 Jan;30(1):1-8. doi: 10.1002/pd.2409.
73 Roles of angiotensin II type 2 receptor in mice with fetal growth restriction.Hypertens Res. 2018 Mar;41(3):157-164. doi: 10.1038/s41440-017-0004-2. Epub 2018 Jan 15.
74 Fetal Growth Restriction Alters Cerebellar Development in Fetal and Neonatal Sheep.Front Physiol. 2019 May 22;10:560. doi: 10.3389/fphys.2019.00560. eCollection 2019.
75 Expression of Biglycan in First Trimester Chorionic Villous Sampling Placental Samples and Altered Function in Telomerase-Immortalized Microvascular Endothelial Cells.Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1168-1179. doi: 10.1161/ATVBAHA.117.309422. Epub 2017 Apr 13.
76 The regulation of apoptosis in intrauterine growth restriction: a study of Bcl-2 and Bax gene expression in human placenta.J Matern Fetal Neonatal Med. 2013 Mar;26(4):347-50. doi: 10.3109/14767058.2012.733770. Epub 2012 Nov 8.
77 Placental Stem Villus Arterial Remodeling Associated with Reduced Hydrogen Sulfide Synthesis Contributes to Human Fetal Growth Restriction.Am J Pathol. 2017 Apr;187(4):908-920. doi: 10.1016/j.ajpath.2016.12.002. Epub 2017 Feb 1.
78 Cullin 7 and Fbxw 8 expression in trophoblastic cells is regulated via oxygen tension: implications for intrauterine growth restriction?.J Matern Fetal Neonatal Med. 2012 Nov;25(11):2209-15. doi: 10.3109/14767058.2012.684166. Epub 2012 May 14.
79 Antiangiogenic effects of decorin restored by unfractionated, low molecular weight, and nonanticoagulant heparins.Blood Adv. 2017 Jul 3;1(16):1243-1253. doi: 10.1182/bloodadvances.2017004333. eCollection 2017 Jul 11.
80 Increased endoplasmic reticulum stress in decidual tissue from pregnancies complicated by fetal growth restriction with and without pre-eclampsia.Placenta. 2011 Nov;32(11):823-9. doi: 10.1016/j.placenta.2011.08.005. Epub 2011 Sep 9.
81 Altered gene expression patterns in intrauterine growth restriction: potential role of hypoxia.Am J Obstet Gynecol. 2007 Jan;196(1):70.e1-6. doi: 10.1016/j.ajog.2006.08.027.
82 Haploinsufficiency at GCK gene is not a frequent event in MODY2 patients.Clin Endocrinol (Oxf). 2008 Jun;68(6):873-8. doi: 10.1111/j.1365-2265.2008.03214.x. Epub 2008 Feb 1.
83 Exome sequencing reveals two novel compound heterozygous XYLT1 mutations in a Polish patient with Desbuquois dysplasia type 2 and growth hormone deficiency.J Hum Genet. 2016 Jul;61(7):577-83. doi: 10.1038/jhg.2016.30. Epub 2016 Mar 31.
84 A novel 2q14.1q14.3 deletion involving GLI2 and RNU4ATAC genes associated with partial corpus callosum agenesis and severe intrauterine growth retardation.Birth Defects Res A Clin Mol Teratol. 2016 Sep;106(9):793-7. doi: 10.1002/bdra.23535. Epub 2016 Jun 27.
85 Genetic disruption of the oncogenic HMGA2-PLAG1-IGF2 pathway causes fetal growth restriction.Genet Med. 2018 Feb;20(2):250-258. doi: 10.1038/gim.2017.105. Epub 2017 Aug 10.
86 Mechanisms for establishment of the placental glucocorticoid barrier, a guard for life.Cell Mol Life Sci. 2019 Jan;76(1):13-26. doi: 10.1007/s00018-018-2918-5. Epub 2018 Sep 17.
87 Decreased placental expression of hPGH, IGF-I and IGFBP-1 in pregnancies complicated by fetal growth restriction.Growth Horm IGF Res. 2011 Feb;21(1):31-6. doi: 10.1016/j.ghir.2010.12.002. Epub 2011 Jan 5.
88 Caffeine-induced fetal rat over-exposure to maternal glucocorticoid and histone methylation of liver IGF-1 might cause skeletal growth retardation.Toxicol Lett. 2012 Nov 15;214(3):279-87. doi: 10.1016/j.toxlet.2012.09.007. Epub 2012 Sep 17.
89 Silencing H19 regulated proliferation, invasion, and autophagy in the placenta by targeting miR-18a-5p.J Cell Biochem. 2019 Jun;120(6):9006-9015. doi: 10.1002/jcb.28172. Epub 2018 Dec 9.
90 Molecular mechanisms of intrauterine growth restriction.J Matern Fetal Neonatal Med. 2018 Oct;31(19):2634-2640. doi: 10.1080/14767058.2017.1347922. Epub 2017 Jul 10.
91 Postnatal effects of intrauterine treatment of the growth-restricted ovine fetus with intra-amniotic insulin-like growth factor-1.J Physiol. 2018 Dec;596(23):5925-5945. doi: 10.1113/JP274999. Epub 2017 Dec 27.
92 Epigenetic Regulation and Its Therapeutic Potential in Pulmonary Hypertension.Front Pharmacol. 2018 Mar 20;9:241. doi: 10.3389/fphar.2018.00241. eCollection 2018.
93 Mitochondrial and glycolysis-regulatory gene expression profiles are associated with intrauterine growth restriction.J Matern Fetal Neonatal Med. 2020 Apr;33(8):1336-1345. doi: 10.1080/14767058.2018.1518419. Epub 2018 Sep 25.
94 Intrauterine growth retardation leads to the functional change of insulin secretion in the newborn rats.Horm Metab Res. 2010 Jun;42(7):491-5. doi: 10.1055/s-0030-1249058. Epub 2010 Mar 11.
95 Placental expression of angiogenesis-related genes and their receptors in IUGR pregnancies: correlation with fetoplacental and maternal parameters.J Matern Fetal Neonatal Med. 2020 Dec;33(23):3954-3961. doi: 10.1080/14767058.2019.1593362. Epub 2019 Mar 28.
96 Placental expression of PAPPA, PAPPA-2 and PLAC-1 in pregnacies is associated with FGR.Mol Med Rep. 2018 May;17(5):6435-6440. doi: 10.3892/mmr.2018.8721. Epub 2018 Mar 9.
97 Antenatal hemodynamic findings and heart rate variability in early school-age children born with fetal growth restriction.J Matern Fetal Neonatal Med. 2021 Jul;34(14):2267-2273. doi: 10.1080/14767058.2019.1663816. Epub 2019 Sep 11.
98 Maternal high-fat diet sex-specifically alters placental morphology and transcriptome in rats: Assessment by next-generation sequencing.Placenta. 2019 Mar;78:44-53. doi: 10.1016/j.placenta.2019.03.004. Epub 2019 Mar 12.
99 Decreased STAT3 in human idiopathic fetal growth restriction contributes to trophoblast dysfunction.Reproduction. 2015 May;149(5):523-32. doi: 10.1530/REP-14-0622. Epub 2015 Feb 23.
100 Reduced l-arginine transport and nitric oxide synthesis in human umbilical vein endothelial cells from intrauterine growth restriction pregnancies is not further altered by hypoxia.Placenta. 2009 Jul;30(7):625-33. doi: 10.1016/j.placenta.2009.04.010. Epub 2009 Jun 7.
101 Role for the thromboxane A2 receptor -isoform in the pathogenesis of intrauterine growth restriction.Sci Rep. 2016 Jul 1;6:28811. doi: 10.1038/srep28811.
102 Potential role of microRNA-424 in regulating ERR to suppress trophoblast proliferation and invasion in fetal growth restriction.Placenta. 2019 Aug;83:57-62. doi: 10.1016/j.placenta.2019.07.001. Epub 2019 Jul 2.
103 Postnatal middle cerebral artery Dopplers in growth-restricted neonates.Eur J Pediatr. 2020 Apr;179(4):571-577. doi: 10.1007/s00431-019-03540-3. Epub 2019 Dec 13.
104 Associations between in utero exposure to polybrominated diphenyl ethers, pathophysiological state of fetal growth and placental DNA methylation changes.Environ Int. 2019 Dec;133(Pt B):105255. doi: 10.1016/j.envint.2019.105255. Epub 2019 Oct 23.
105 Effects of Arachidonic and Docosohexahenoic Acid Supplementation during Gestation in Rats. Implication of Placental Oxidative Stress.Int J Mol Sci. 2018 Dec 4;19(12):3863. doi: 10.3390/ijms19123863.
106 Nutritional Intervention for Developmental Brain Damage: Effects of Lactoferrin Supplementation in Hypocaloric Induced Intrauterine Growth Restriction Rat Pups.Front Endocrinol (Lausanne). 2019 Feb 8;10:46. doi: 10.3389/fendo.2019.00046. eCollection 2019.
107 Alterations in placental long chain polyunsaturated fatty acid metabolism in human intrauterine growth restriction.Clin Sci (Lond). 2018 Mar 15;132(5):595-607. doi: 10.1042/CS20171340. Print 2018 Mar 15.
108 Localization and quantification of glucose transporters in liver of growth-retarded fetal and neonatal rats.Am J Physiol. 1999 Jan;276(1):E135-42. doi: 10.1152/ajpendo.1999.276.1.E135.
109 Impaired cell fusion and differentiation in placentae from patients with intrauterine growth restriction correlate with reduced levels of HERV envelope genes.J Mol Med (Berl). 2010 Nov;88(11):1143-56. doi: 10.1007/s00109-010-0656-8. Epub 2010 Jul 28.
110 Fatty acid profile of maternal and fetal erythrocytes and placental expression of fatty acid transport proteins in normal and intrauterine growth restriction pregnancies.Prostaglandins Leukot Essent Fatty Acids. 2017 Oct;125:24-31. doi: 10.1016/j.plefa.2017.08.011. Epub 2017 Aug 24.
111 Enhanced expression of intercellular adhesion molecule-1 (ICAM-1) in amnion with term and preterm labour.Placenta. 2000 Jan;21(1):115-21. doi: 10.1053/plac.1999.0457.
112 Essential amino acid transporter Lat4 (Slc43a2) is required for mouse development.J Physiol. 2015 Mar 1;593(5):1273-89. doi: 10.1113/jphysiol.2014.283960. Epub 2015 Jan 16.
113 NFAT5 Is Up-Regulated by Hypoxia: Possible Implications in Preeclampsia and Intrauterine Growth Restriction.Biol Reprod. 2015 Jul;93(1):14. doi: 10.1095/biolreprod.114.124644. Epub 2015 May 20.
114 Taurine transport in human placental trophoblast is important for regulation of cell differentiation and survival.Cell Death Dis. 2013 Mar 21;4(3):e559. doi: 10.1038/cddis.2013.81.
115 Slc20a2 deficiency results in fetal growth restriction and placental calcification associated with thickened basement membranes and novel CD13 and laminin1 expressing cells.Reprod Biol. 2016 Mar;16(1):13-26. doi: 10.1016/j.repbio.2015.12.004. Epub 2016 Jan 11.
116 Placental glucose transporter 3 (GLUT3) is up-regulated in human pregnancies complicated by late-onset intrauterine growth restriction.Placenta. 2013 Nov;34(11):1072-8. doi: 10.1016/j.placenta.2013.08.010. Epub 2013 Aug 28.
117 Effect of reduced maternal inspired oxygen on hepatic glucose metabolism in the rat fetus.Pediatr Res. 2003 Feb;53(2):325-32. doi: 10.1203/01.PDR.0000047643.26484.48.
118 The exposure to uteroplacental insufficiency is associated with activation of unfolded protein response in postnatal life.PLoS One. 2018 Jun 13;13(6):e0198490. doi: 10.1371/journal.pone.0198490. eCollection 2018.
119 The imprinted region on human chromosome 7q32 extends to the carboxypeptidase A gene cluster: an imprinted candidate for Silver-Russell syndrome.J Med Genet. 2003 Apr;40(4):249-56. doi: 10.1136/jmg.40.4.249.
120 An essential role for angiotensin II type 1a receptor in pregnancy-associated hypertension with intrauterine growth retardation.FASEB J. 2004 Feb;18(2):388-90. doi: 10.1096/fj.03-0321fje. Epub 2003 Dec 19.
121 Paraoxonase-2 and paraoxonase-3: comparison of mRNA expressions in the placentae of unexplained intrauterine growth restricted and noncomplicated pregnancies.J Matern Fetal Neonatal Med. 2017 May;30(10):1200-1206. doi: 10.1080/14767058.2016.1209480. Epub 2016 Jul 29.
122 Expression of enzymes regulating placental ammonia homeostasis in human fetal growth restricted pregnancies.Placenta. 2009 Jul;30(7):607-12. doi: 10.1016/j.placenta.2009.05.005. Epub 2009 Jun 4.
123 Maternal tobacco use modestly alters correlated epigenome-wide placental DNA methylation and gene expression.Epigenetics. 2011 Nov;6(11):1284-94. doi: 10.4161/epi.6.11.17819. Epub 2011 Nov 1.
124 Uteroplacental Insufficiency Impairs Cholesterol Elimination in Adult Female Growth-Restricted Rat Offspring Fed a High-Fat Diet.Reprod Sci. 2019 Sep;26(9):1173-1180. doi: 10.1177/1933719118811649. Epub 2018 Nov 19.
125 The impact of placental massive perivillous fibrin deposition on neonatal outcome in pregnancies complicated by fetal growth restriction.Placenta. 2019 Nov;87:46-52. doi: 10.1016/j.placenta.2019.09.007. Epub 2019 Sep 17.
126 Maternal docosahexaenoic acid increases adiponectin and normalizes IUGR-induced changes in rat adipose deposition.J Obes. 2013;2013:312153. doi: 10.1155/2013/312153. Epub 2013 Mar 6.
127 Combination of first trimester serum afamin levels and three-dimensional placental bed vascularization as a possible screening method to detect women at-risk for adverse pregnancy complications like pre-eclampsia and gestational diabetes mellitus in low-risk pregnancies.Placenta. 2018 Feb;62:9-15. doi: 10.1016/j.placenta.2017.12.014. Epub 2017 Dec 15.
128 Aldehyde dehydrogenase isoforms and inflammatory cell populations are differentially expressed in term human placentas affected by intrauterine growth restriction.Placenta. 2019 Jun;81:9-17. doi: 10.1016/j.placenta.2019.03.015. Epub 2019 Apr 8.
129 Overexpression of the aryl hydrocarbon receptor nuclear translocator partially rescues fetoplacental angiogenesis in severe fetal growth restriction.Clin Sci (Lond). 2019 Jun 20;133(12):1353-1365. doi: 10.1042/CS20190381. Print 2019 Jun 28.
130 Fetal stroke and cerebrovascular disease: Advances in understanding from lenticulostriate and venous imaging, alloimmune thrombocytopaenia and monochorionic twins.Eur J Paediatr Neurol. 2018 Nov;22(6):989-1005. doi: 10.1016/j.ejpn.2018.08.008. Epub 2018 Sep 11.
131 Mechanisms Underpinning Adaptations in Placental Calcium Transport in Normal Mice and Those With Fetal Growth Restriction.Front Endocrinol (Lausanne). 2018 Nov 20;9:671. doi: 10.3389/fendo.2018.00671. eCollection 2018.
132 Gender-specific effects of intrauterine growth restriction on the adipose tissue of adult rats: a proteomic approach.Proteome Sci. 2015 Dec 2;13:32. doi: 10.1186/s12953-015-0088-z. eCollection 2015.
133 Proteomic Analysis of One-carbon Metabolism-related Marker in Liver of Rat Offspring.Mol Cell Proteomics. 2015 Nov;14(11):2901-9. doi: 10.1074/mcp.M114.046888. Epub 2015 Sep 4.
134 Expression of von Willebrand factor and caldesmon in the placental tissues of pregnancies complicated with intrauterine growth restriction.J Matern Fetal Neonatal Med. 2019 Mar;32(6):916-921. doi: 10.1080/14767058.2017.1395017. Epub 2017 Nov 2.
135 Recurrent intrauterine growth restriction: characteristic placental histopathological features and association with prenatal vascular Doppler.Arch Gynecol Obstet. 2019 Dec;300(6):1583-1589. doi: 10.1007/s00404-019-05339-x. Epub 2019 Oct 30.
136 Tadalafil treatment in mice for preeclampsia with fetal growth restriction has neuro-benefic effects in offspring through modulating prenatal hypoxic conditions.Sci Rep. 2019 Jan 18;9(1):234. doi: 10.1038/s41598-018-36084-x.
137 Prospective Cohort Study of Congenital Cytomegalovirus Infection during Pregnancy with Fetal Growth Restriction: Serologic Analysis and Placental Pathology.J Pediatr. 2019 Mar;206:42-48.e2. doi: 10.1016/j.jpeds.2018.10.003. Epub 2018 Nov 6.
138 The role of insulin-like growth factor 2 receptor-mediated homeobox gene expression in human placental apoptosis, and its implications in idiopathic fetal growth restriction.Mol Hum Reprod. 2019 Sep 1;25(9):572-585. doi: 10.1093/molehr/gaz047.
139 Maternal Protein Restriction Induces Alterations in Hepatic Unfolded Protein Response-Related Molecules in Adult Rat Offspring.Front Endocrinol (Lausanne). 2018 Nov 20;9:676. doi: 10.3389/fendo.2018.00676. eCollection 2018.
140 Antenatal taurine supplementation in fetal rats with growth restriction improves neural stem cell proliferation by inhibiting the activities of Rho family factors.J Matern Fetal Neonatal Med. 2018 Jun;31(11):1454-1461. doi: 10.1080/14767058.2017.1319353. Epub 2017 May 5.
141 Lectin pathway proteins of the complement system in normotensive pregnancy and pre-eclampsia.Am J Reprod Immunol. 2019 Apr;81(4):e13092. doi: 10.1111/aji.13092. Epub 2019 Feb 23.
142 Fetal Growth Restriction Is Associated With Decreased Number of Ovarian Follicles and Impaired Follicle Growth in Young Adult Guinea Pig Offspring.Reprod Sci. 2019 Dec;26(12):1557-1567. doi: 10.1177/1933719119828041. Epub 2019 Feb 11.
143 Transcriptomic Analysis Reveals Novel Mechanisms Mediating Islet Dysfunction in the Intrauterine Growth-Restricted Rat.Endocrinology. 2018 Feb 1;159(2):1035-1049. doi: 10.1210/en.2017-00888.
144 Down-regulated expressed protein HMGB3 inhibits proliferation and migration, promotes apoptosis in the placentas of fetal growth restriction.Int J Biochem Cell Biol. 2019 Feb;107:69-76. doi: 10.1016/j.biocel.2018.11.007. Epub 2018 Dec 10.
145 Down-regulation of DKK1 and Wnt1/-catenin pathway by increased homeobox B7 resulted in cell differentiation suppression of intrauterine fetal growth retardation in human placenta.Placenta. 2019 May;80:27-35. doi: 10.1016/j.placenta.2019.03.001. Epub 2019 Mar 11.
146 Combination of serum histidine-rich glycoprotein and uterine artery Doppler to predict preeclampsia.Hypertens Res. 2018 Apr;41(4):275-281. doi: 10.1038/s41440-018-0013-9. Epub 2018 Feb 7.
147 Intrauterine growth restriction combined with a maternal high-fat diet increased adiposity and serum corticosterone levels in adult rat offspring.J Dev Orig Health Dis. 2018 Jun;9(3):315-328. doi: 10.1017/S2040174418000016. Epub 2018 Feb 5.
148 Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3 in Perinatal Survival and Postnatal Growth Using New Genetically Engineered Mouse Models.Mol Cell Biol. 2019 Mar 1;39(6):e00527-18. doi: 10.1128/MCB.00527-18. Print 2019 Mar 15.
149 Association between expression of long noncoding RNAs in placenta and pregnancy features.Per Med. 2019 Nov;16(6):457-466. doi: 10.2217/pme-2018-0078. Epub 2019 Nov 6.
150 Prenatal findings and molecular cytogenetic analyses of a de novo interstitial deletion of 1q23.3 encompassing PBX1 gene.Taiwan J Obstet Gynecol. 2019 Mar;58(2):292-295. doi: 10.1016/j.tjog.2019.01.022.
151 Increased pyruvate dehydrogenase activity in skeletal muscle of growth-restricted ovine fetuses.Am J Physiol Regul Integr Comp Physiol. 2019 Oct 1;317(4):R513-R520. doi: 10.1152/ajpregu.00106.2019. Epub 2019 Jul 17.
152 Label-Free Proteomics of the Fetal Pancreas Identifies Deficits in the Peroxisome in Rats with Intrauterine Growth Restriction.Oxid Med Cell Longev. 2019 Nov 3;2019:1520753. doi: 10.1155/2019/1520753. eCollection 2019.
153 [Increased expression of gluconeogenic enzymes in the liver of IUGR rats and subsequent insulin resistance].Zhongguo Dang Dai Er Ke Za Zhi. 2008 Apr;10(2):216-20.
154 Expression and Regulation of Retinoic Acid Receptor Responders in the Human Placenta.Reprod Sci. 2018 Sep;25(9):1357-1370. doi: 10.1177/1933719117746761. Epub 2017 Dec 15.
155 Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1.J Clin Invest. 2008 Jun;118(6):2316-24. doi: 10.1172/JCI33655.
156 The genetics of signal transduction and the effect of smoking on intrauterine growth.Int J Epidemiol. 2001 Apr;30(2):400-2. doi: 10.1093/ije/30.2.400.
157 Alpha-hemoglobin-stabilizing protein (AHSP) in hemolysis, elevated liver enzyme, and low platelet (HELLP) syndrome, intrauterine growth restriction (IUGR) and fetal death.Cell Stress Chaperones. 2008 Spring;13(1):67-71. doi: 10.1007/s12192-008-0009-5. Epub 2008 Feb 6.
158 Intrauterine growth retardation promotes fetal intestinal autophagy in rats via the mechanistic target of rapamycin pathway.J Reprod Dev. 2017 Dec 15;63(6):547-554. doi: 10.1262/jrd.2017-050. Epub 2017 Aug 31.
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160 Uric Acid Crystals Induce Placental Inflammation and Alter Trophoblast Function via an IL-1-Dependent Pathway: Implications for Fetal Growth Restriction.J Immunol. 2017 Jan 1;198(1):443-451. doi: 10.4049/jimmunol.1601179. Epub 2016 Nov 30.
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202 Mutations in the MRPS28 gene encoding the small mitoribosomal subunit protein bS1m in a patient with intrauterine growth retardation, craniofacial dysmorphism and multisystemic involvement. Hum Mol Genet. 2019 May 1;28(9):1445-1462. doi: 10.1093/hmg/ddy441.
203 l-Threonine improves intestinal mucin synthesis and immune function of intrauterine growth-retarded weanling piglets.Nutrition. 2019 Mar;59:182-187. doi: 10.1016/j.nut.2018.07.114. Epub 2018 Aug 22.
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205 Small 4p16.3 deletions: Three additional patients and review of the literature.Am J Med Genet A. 2018 Nov;176(11):2501-2508. doi: 10.1002/ajmg.a.40512. Epub 2018 Sep 23.
206 Mutations in ORC1, encoding the largest subunit of the origin recognition complex, cause microcephalic primordial dwarfism resembling Meier-Gorlin syndrome. Nat Genet. 2011 Feb 27;43(4):350-5. doi: 10.1038/ng.776.
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218 Homeobox gene transforming growth factor -induced factor-1 (TGIF-1) is a regulator of villous trophoblast differentiation and its expression is increased in human idiopathic fetal growth restriction.Mol Hum Reprod. 2013 Oct;19(10):665-75. doi: 10.1093/molehr/gat042. Epub 2013 Jun 11.
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