Details of the Drug

General Information of Drug (ID: DMFAMNH)

Drug Name
99mTc-rBitistatin
Indication
Disease Entry ICD 11 Status REF
Embolism JB42 Phase 1/2 [1]
Cross-matching ID
TTD ID
D0UZ4G

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glycoprotein IIb/IIIa receptor (GPIIb/IIIa) TT38RM1 ITA2B_HUMAN ; ITB3_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Embolism
ICD Disease Classification JB42
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Glycoprotein IIb/IIIa receptor (GPIIb/IIIa) DTT ITGA2B; ITGB3 7.83E-01 -0.11 -0.45
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT00808626) Phase II Investigation of 99mTc-rBitistatin for Imaging Venous Thrombosis. U.S. National Institutes of Health.
2 Platelet binding and biodistribution of [99mTc]rBitistatin in animal species and humans. Nucl Med Biol. 2007 Oct;34(7):855-63.