Details of the Drug

General Information of Drug (ID: DMGPDEF)

• Drug Name: US9475795, 19
• Synonyms: CHEMBL3891428; SCHEMBL15549092; UOPFZPMEKNDBSU-UHFFFAOYSA-N; BDBM250540; US9475795, 19; 4-Phenoxy-1-[(1,3,5-trimethyl-1H-pyrazol-4-yl)sulfonyl]piperidine
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 349.4
  Logarithm of the Partition Coefficient (xlogp); 2.4
  Rotatable Bond Count (rotbonds); 4
  Hydrogen Bond Donor Count (hbonddonor); 0
  Hydrogen Bond Acceptor Count (hbondacc); 5
• Chemical Identifiers:
  Formula: C17H23N3O3S
  IUPAC Name: 4-phenoxy-1-(1,3,5-trimethylpyrazol-4-yl)sulfonylpiperidine
  Canonical SMILES: CC1=C(C(=NN1C)C)S(=O)(=O)N2CCC(CC2)OC3=CC=CC=C3
  InChI: InChI=1S/C17H23N3O3S/c1-13-17(14(2)19(3)18-13)24(21,22)20-11-9-16(10-12-20)23-15-7-5-4-6-8-15/h4-8,16H,9-12H2,1-3H3
  InChIKey: UOPFZPMEKNDBSU-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 72549319
  TTD ID: D0X1ZY

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prokineticin receptor-1 (PROKR1)	TTB9CIL	PKR1_HUMAN	Inhibitor	[1]

References

• [1] Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases. US9475795.