Details of the Drug

General Information of Drug (ID: DMH6B9J)

• Drug Name: BZ-55
• Synonyms: Alentin; Aminophenurobutane; Bucarban; Bucrol; Bukarban; Burcol; Butisulfina; Carbutamid; Carbutamide; Carbutamide [INN:BAN]; Diabetin; Diabetoplex; Diaboral; Diabutan; Emedan; Glucidoral; Glucofren; Glybutamide; Inbuton; Invenol; N'-(Butylcarbamoyl)sulfanilamide; N-Butyl-N'-sulfanilylurea; N-Butylsulfanilylurea; N-Sulfanilyl-N'-butylurea; Nadisan; Nadizan; Norboral; Oranil; Oranyl; Orasulin; Sulfonamide carbutamide; Urea, 1-butyl-3-sulfanilyl-; 1-BUTYL-3-SULFANILYLUREA; 339-43-5; 4-amino-N-[(butylamino)carbonyl]benzenesulfonamide; BZ 55
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 271.34
  Logarithm of the Partition Coefficient (xlogp); 1
  Rotatable Bond Count (rotbonds); 5
  Hydrogen Bond Donor Count (hbonddonor); 3
  Hydrogen Bond Acceptor Count (hbondacc); 4
• Chemical Identifiers:
  Formula: C11H17N3O3S
  IUPAC Name: 1-(4-aminophenyl)sulfonyl-3-butylurea
  Canonical SMILES: CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)N
  InChI: VDTNNGKXZGSZIP-UHFFFAOYSA-N
  InChIKey: 1S/C11H17N3O3S/c1-2-3-8-13-11(15)14-18(16,17)10-6-4-9(12)5-7-10/h4-7H,2-3,8,12H2,1H3,(H2,13,14,15)
• Cross-matching ID:
  PubChem CID: 9564
  ChEBI ID: CHEBI:135118
  CAS Number: 339-43-5
  INTEDE ID: DR0274

Molecular Interaction Atlas of This Drug

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Cytochrome P450 2C9 (CYP2C9) Main DME	DE5IED8	CP2C9_HUMAN	Substrate	[1]

References

• [1] Clinically and pharmacologically relevant interactions of antidiabetic drugs. Ther Adv Endocrinol Metab. 2016 Apr;7(2):69-83.