Details of the Drug

General Information of Drug (ID: DMH8IT5)

Drug Name
Donaperminogene seltoplasmid
Synonyms VM202
Indication
Disease Entry ICD 11 Status REF
Diabetic foot ulcer BD54 Phase 3 [1]
Diabetic neuropathy 8C0Z Phase 3 [2]
Amyotrophic lateral sclerosis 8B60.0 Phase 1/2 [3]
Drug Type
Gene therapy
Cross-matching ID
TTD ID
D9CI7V
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Hepatocyte growth factor (HGF) TT4V2JM HGF_HUMAN Replacement [4]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Diabetic foot ulcer
ICD Disease Classification BD54
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Hepatocyte growth factor (HGF) DTT HGF 4.90E-01 0.13 2.73
Hepatocyte growth factor (HGF) DTT HGF 1.98E-07 1.58 2.92
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT02563522) Safety and Efficacy Study of VM202 in the Treatment of Chronic Non-Healing Foot Ulcers. U.S. National Institutes of Health.
2 ClinicalTrials.gov (NCT02427464) Phase 3 Gene Therapy for Painful Diabetic Neuropathy. U.S. National Institutes of Health.
3 ClinicalTrials.gov (NCT02039401) Safety Study of VM202 to Treat Amyotrophic Lateral Sclerosis. U.S. National Institutes of Health.
4 Clinical pipeline report, company report or official report of ViroMed.