General Information of Drug (ID: DMHJG5N)

Drug Name
(9-Benzyl-9H-purin-6-yl)-cyclopropyl-amine
Synonyms CHEMBL7583
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 265.31
Logarithm of the Partition Coefficient (xlogp) 2.9
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C15H15N5
IUPAC Name
9-benzyl-N-cyclopropylpurin-6-amine
Canonical SMILES
C1CC1NC2=C3C(=NC=N2)N(C=N3)CC4=CC=CC=C4
InChI
InChI=1S/C15H15N5/c1-2-4-11(5-3-1)8-20-10-18-13-14(19-12-6-7-12)16-9-17-15(13)20/h1-5,9-10,12H,6-8H2,(H,16,17,19)
InChIKey
AVSPKBDDPGPKRA-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
14022446
TTD ID
D02XXK

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
GABA(A) receptor alpha-1 (GABRA1) TT1MPAY GBRA1_HUMAN Inhibitor [1]
GABA(A) receptor beta-2 (GABRB2) TTZA1NY GBRB2_HUMAN Inhibitor [1]
GABA(A) receptor gamma-2 (GABRG2) TT06RH5 GBRG2_HUMAN Inhibitor [1]
Gamma-aminobutyric acid receptor (GAR) TTNJYV2 NOUNIPROTAC Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Benzodiazepine receptor binding activity of 6,9-disubstituted purines. J Med Chem. 1989 May;32(5):1020-4.