Details of the Drug

General Information of Drug (ID: DMHOLQF)

• Drug Name: Benzyl pyrrolyloxoacetamide derivative 2
• Synonyms: PMID26413912-Compound-90
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 484.4
  Logarithm of the Partition Coefficient (xlogp); 3.2
  Rotatable Bond Count (rotbonds); 7
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 9
• Chemical Identifiers:
  Formula: C24H19F3N4O4
  IUPAC Name: 2-[1-[(3,5-difluoropyridin-2-yl)methyl]-6-fluoro-5-methoxy-2-methylindol-3-yl]-N-(2-methoxypyridin-4-yl)-2-oxoacetamide
  Canonical SMILES: CC1=C(C2=CC(=C(C=C2N1CC3=C(C=C(C=N3)F)F)F)OC)C(=O)C(=O)NC4=CC(=NC=C4)OC
  InChI: InChI=1S/C24H19F3N4O4/c1-12-22(23(32)24(33)30-14-4-5-28-21(7-14)35-3)15-8-20(34-2)17(27)9-19(15)31(12)11-18-16(26)6-13(25)10-29-18/h4-10H,11H2,1-3H3,(H,28,30,33)
  InChIKey: SUOOBQNAIURDKV-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 67984463
  TTD ID: D04VYE

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fatty acid amide hydrolase (FAAH)	TTDP1UC	NOUNIPROTAC	Inhibitor	[1]

Molecular Expression Atlas of This Drug

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Fatty acid amide hydrolase (FAAH)	DTT	NO-GeName	2.65E-01	0.02	0.1

References

• [1] Fatty acid amide hydrolase inhibitors: a patent review (2009-2014).Expert Opin Ther Pat. 2015;25(11):1247-66.