General Information of Drug (ID: DMHRY8A)

Drug Name
THR-687
Indication
Disease Entry ICD 11 Status REF
Diabetic macular edema 9B71.02 Phase 1 [1]
Diabetic retinopathy 9B71.0 Phase 1 [1]
Drug Type
Small molecular drug
Cross-matching ID
TTD ID
DS6OV9

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Integrin (ITG) TTQFP08 NOUNIPROTAC Antagonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03666923) A Study to Evaluate the Safety of THR-687 in Subjects With Diabetic Macular Edema (DME). U.S. National Institutes of Health.
2 The potent small molecule integrin antagonist THR-687 is a promising next-generation therapy for retinal vascular disorders. Exp Eye Res. 2019 Mar;180:43-52.