Details of the Drug

General Information of Drug (ID: DMHRYX6)

Drug Name
SLV-323
Indication
Disease Entry ICD 11 Status REF
Chemotherapy-induced nausea MD90 Discontinued in Phase 1 [1]
Gastric motility disorder DA21 Discontinued in Phase 1 [1]
Irritable bowel syndrome DD91.0 Discontinued in Phase 1 [1]
Cross-matching ID
TTD ID
D00VPU
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Substance-P receptor (TACR1) TTZPO1L NK1R_HUMAN Modulator [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Chemotherapy-induced nausea
ICD Disease Classification MD90
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Substance-P receptor (TACR1) DTT TACR1 7.24E-01 0.02 0.11
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Emerging drugs for chemotherapy-induced emesis. Expert Opin Emerg Drugs. 2006 Mar;11(1):137-51.