Details of the Drug

General Information of Drug (ID: DMI4E9K)

Drug Name
MLN0264
Indication
Disease Entry ICD 11 Status REF
Gastrointestinal cancer 2C11 Phase 2 [1]
Cross-matching ID
TTD ID
D0U7VU

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Guanylyl cyclase C (GUCY2C) TTLDPRG GUC2C_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Gastrointestinal cancer
ICD Disease Classification 2C11
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Guanylyl cyclase C (GUCY2C) DTT GUCY2C 9.52E-03 2.35 5.13
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT02202759) A Study of MLN0264 in Patients With Cancer of the Stomach or Gastroesophageal Junction. U.S. National Institutes of Health.
2 J Clin Oncol 31, 2013 (suppl; abstr TPS3646).