Details of the Drug

General Information of Drug (ID: DMI6VG9)

Drug Name
Tetra-hydro-triazolopyrimidine derivative 2
Synonyms PMID29171765-Compound-Figure4
Structure 3D Structure is Not Available
3D MOL 2D MOL
Cross-matching ID
TTD ID
D07RRV

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Neutrophil elastase (NE) TTPLTSQ ELNE_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Neutrophil elastase (NE) DTT ELANE 9.42E-01 0.02 0.07
Neutrophil elastase (NE) DTT ELANE 1.43E-02 0.05 0.2
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Serine protease inhibitors to treat inflammation: a patent review (2011-2016).Expert Opin Ther Pat. 2018 Feb;28(2):93-110.