Details of the Drug

General Information of Drug (ID: DMIEJ0W)

Drug Name
Radiolabelled-huA33
Synonyms Radiolabelled-huA33 (colorectal cancer); Radiolabelled-huA33 (colorectal cancer), Ludwig; 124I-huA33; 125I-huA33
Indication
Disease Entry ICD 11 Status REF
Colorectal cancer 2B91.Z Phase 1 [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
D0LY0C

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cell surface A33 antigen (GPA33) TT96HUR GPA33_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Colorectal cancer
ICD Disease Classification 2B91.Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Cell surface A33 antigen (GPA33) DTT GPA33 1.62E-10 -1.19 -5.77
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT00291486) Capecitabine and 131I-huA33 in Patients With Metastatic Colorectal Cancer. U.S. National Institutes of Health.
2 (124)I-huA33 antibody PET of colorectal cancer. J Nucl Med. 2011 Aug;52(8):1173-80.