Details of the Drug

General Information of Drug (ID: DMIQAY4)

Drug Name
VER-155008
Synonyms Heat shock protein 70 inhibitor (cancer), Vernalis; Hsp 70 inhibitor (cancer), Vernalis
Indication
Disease Entry ICD 11 Status REF
Alzheimer disease 8A20 Preclinical [1]
Solid tumour/cancer 2A00-2F9Z Investigative [2]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C25H23Cl2N7O4
Canonical SMILES
C1=CC(=CC=C1COCC2C(C(C(O2)N3C4=NC=NC(=C4N=C3NCC5=CC(=C(C=C5)Cl)Cl)N)O)O)C#N
InChI
1S/C25H23Cl2N7O4/c26-16-6-5-15(7-17(16)27)9-30-25-33-19-22(29)31-12-32-23(19)34(25)24-21(36)20(35)18(38-24)11-37-10-14-3-1-13(8-28)2-4-14/h1-7,12,18,20-21,24,35-36H,9-11H2,(H,30,33)(H2,29,31,32)/t18-,20-,21-,24-/m1/s1
InChIKey
ZXGGCBQORXDVTE-UMCMBGNQSA-N
Cross-matching ID
PubChem CID
25195348
ChEBI ID
CHEBI:95010
CAS Number
1134156-31-2
TTD ID
D0H0AU
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References

1 Lysosomes as a therapeutic target. Nat Rev Drug Discov. 2019 Dec;18(12):923-948.
2 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.