Details of the Drug

General Information of Drug (ID: DMIRBYE)

Drug Name
Fluoro-Phosphite Ion
Synonyms
Fluorophosphate; FLUORO-PHOSPHITE ION; Phosphorofluoridate; UNII-4964UZ79MI; 15181-43-8; 4964UZ79MI; Monofluorophosphate(2-); Fluorotrioxophosphate(2-); Fluorophosphate (FPO32-); Monofluorophostae (PO3F2-); fluoridophosphate; Fluorophosphate ion (PFO32-); fluoro-dioxido-oxo-; AC1L22VV; fluoridotrioxidophosphate(2-); Phosphorofluoridate(8CI,9CI); CHEBI:42699; CTK0H6578; DTXSID90164882; 7789-74-4 (calcium salt); 15600-53-0 (barium salt); DB02348; [PFO3](2-); 10163-15-2 (di-hydrochloride salt); 7631-97-2 (unspecified hydrochloride sa
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 97.97
Logarithm of the Partition Coefficient (xlogp) -1.2
Rotatable Bond Count (rotbonds) 0
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
FO3P-2
IUPAC Name
fluoro-dioxido-oxo-lambda5-phosphane
Canonical SMILES
[O-]P(=O)([O-])F
InChI
InChI=1S/FH2O3P/c1-5(2,3)4/h(H2,2,3,4)/p-2
InChIKey
DWYMPOCYEZONEA-UHFFFAOYSA-L
Cross-matching ID
PubChem CID
65241
ChEBI ID
CHEBI:42699
CAS Number
15181-43-8
DrugBank ID
DB02348
TTD ID
D05DGE

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glycogen phosphorylase muscle form (GP) TTZHY6R PYGM_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Glycogen phosphorylase muscle form (GP) DTT PYGM 2.69E-01 -0.23 -0.14
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.