General Information of Drug (ID: DMIUCSW)

Drug Name
Cyclohexyl-(9-methyl-9H-purin-6-yl)-amine
Synonyms
CHEMBL95332; 109292-93-5; 9H-Purin-6-amine, N-cyclohexyl-9-methyl-; N6-Cyclohexyl-9-methyladenine; Cyclohexyl-(9-methyl-9H-purin-6-yl)-amine; ACMC-20mc61; SCHEMBL14564552; CTK0D5868; DTXSID10576963; BDBM50009683; 6-Cyclohexylamino-9-methyl-9H-purine; AKOS030562210
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 231.3
Logarithm of the Partition Coefficient (xlogp) 2.4
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C12H17N5
IUPAC Name
N-cyclohexyl-9-methylpurin-6-amine
Canonical SMILES
CN1C=NC2=C(N=CN=C21)NC3CCCCC3
InChI
InChI=1S/C12H17N5/c1-17-8-15-10-11(13-7-14-12(10)17)16-9-5-3-2-4-6-9/h7-9H,2-6H2,1H3,(H,13,14,16)
InChIKey
YWCWGJZQICOVCA-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
15693939
CAS Number
109292-93-5
TTD ID
D08VXF

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adenosine A1 receptor (ADORA1) TTK25J1 AA1R_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor. J Med Chem. 1991 Sep;34(9):2877-82.