General Information of Drug (ID: DMIY134)

Drug Name
ANA-04
Synonyms ANA-506; ANA-506); ANB-004; Human monoclonal antibody (inflammatory disease/autoimmune disease), AnaptysBio; Multi-specific antibody (autoimmune disease/inflammatory disease), AnaptysBio/VLST Corp
Indication
Disease Entry ICD 11 Status REF
Autoimmune diabetes 5A10 Investigative [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
D04PAF

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin 17 receptor (IL17R) TT69OHW I17RA_HUMAN ; I17RB_HUMAN ; I17RC_HUMAN ; I17RD_HUMAN ; I17RE_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Autoimmune diabetes
ICD Disease Classification 5A10
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Interleukin 17 receptor (IL17R) DTT IL17RA; IL17RB; IL17RC; IL17RD; IL17RE 3.40E-10 -0.23 -0.72
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2294).