Details of the Drug

General Information of Drug (ID: DMJDT5O)

Drug Name
VIS513
Indication
Disease Entry ICD 11 Status REF
Dengue 1D20-1D2Z Preclinical [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
DI8ZG7

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dengue virus Envelope (DENV E) TTMYZNX POLG_DEN1W (281-775) Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Preclinical evaluation of VIS513, a therapeutic antibody against dengue virus, in non-human primates. Antiviral Res. 2017 Aug;144:44-47.
2 Neutralization of antibody-enhanced dengue infection by VIS513, a pan serotype reactive monoclonal antibody targeting domain III of the dengue E protein. PLoS Negl Trop Dis. 2018 Feb 9;12(2):e0006209.