Details of the Drug

General Information of Drug (ID: DMKDTO4)

Drug Name	Quinoline and quinazoline derivative 1
Synonyms	PMID28621580-Compound-US20120219522c30
Drug Type	Small molecular drug
Structure	3D Structure is Not Available
Structure	3D MOL	2D MOL
Cross-matching ID	TTD ID D08OXH

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Vascular endothelial growth factor receptor 2 (KDR)	TTUTJGQ	VGFR2_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Vascular endothelial growth factor receptor 2 (KDR)	DTT	KDR	6.79E-01	0.05	0.19
Vascular endothelial growth factor receptor 2 (KDR)	DTT	KDR	7.67E-01	0.61	0.61

Molecular Expression Atlas (MEA)

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References

1	VEGFR-2 inhibitors and the therapeutic applications thereof: a patent review (2012-2016).Expert Opin Ther Pat. 2017 Sep;27(9):987-1004.