Details of the Drug

General Information of Drug (ID: DMKLCRI)

Drug Name
ARC-183
Synonyms Anti-thrombin aptamer (CABG surgery), Archemix/Nuvelo
Indication
Disease Entry ICD 11 Status REF
Blood forming organ disorder JB64.1 Discontinued in Phase 1 [1]
Drug Type
Aptamer
Cross-matching ID
TTD ID
D0W5XT

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor IIa (F2) TT6L509 THRB_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019755)
2 A high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity. J Thromb Haemost. 2012 May;10(5):870-80.