Details of the Drug

General Information of Drug (ID: DMLM2WU)

• Drug Name: 2-fluorophenyl 4-(heptyloxy)phenylcarbamate
• Synonyms: 2-fluorophenyl 4-(heptyloxy)phenylcarbamate; CHEMBL610774

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 1:
  Molecular Weight (mw); 345.4
  Logarithm of the Partition Coefficient (xlogp); 6
  Rotatable Bond Count (rotbonds); 10
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 4
• Chemical Identifiers:
  Formula: C20H24FNO3
  IUPAC Name: (2-fluorophenyl) N-(4-heptoxyphenyl)carbamate
  Canonical SMILES: CCCCCCCOC1=CC=C(C=C1)NC(=O)OC2=CC=CC=C2F
  InChI: InChI=1S/C20H24FNO3/c1-2-3-4-5-8-15-24-17-13-11-16(12-14-17)22-20(23)25-19-10-7-6-9-18(19)21/h6-7,9-14H,2-5,8,15H2,1H3,(H,22,23)
  InChIKey: SHLSOZYYUDUBRA-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 20872694
  TTD ID: D07PLS

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fatty acid amide hydrolase (FAAH)	TTDP1UC	NOUNIPROTAC	Inhibitor	[1]

Molecular Expression Atlas of This Drug

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Fatty acid amide hydrolase (FAAH)	DTT	NO-GeName	2.65E-01	0.02	0.1

References

• [1] Oxime carbamate--discovery of a series of novel FAAH inhibitors. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1272-7.