Details of the Drug

General Information of Drug (ID: DMM4EJI)

Drug Name
Resten-NG
Synonyms Resten-NG (TN)
Indication
Disease Entry ICD 11 Status REF
Coronary artery disease BA80 Phase 2 [1]
Solid tumour/cancer 2A00-2F9Z Phase 2 [1]
Drug Type
Antisense drug
Cross-matching ID
TTD ID
D0M4MG
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Myc messenger RNA (MYC mRNA) TTNQ5ZP MYC_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

ICD Disease Classification 11 Disease of the circulatory system
Disease Class ICD-11: BA80 Coronary artery disease
The Studied Tissue Peripheral blood
The Studied Disease Coronary artery disease [ICD-11:BA80-BA8Z]
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Myc messenger RNA (MYC mRNA) DTT MYC 6.09E-01 0.25 0.37
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Technology evaluation: AVI-4126, AVI BioPharma. Curr Opin Mol Ther. 2004 Oct;6(5):551-8.
2 Local delivery of c-myc neutrally charged antisense oligonucleotides with transport catheter inhibits myointimal hyperplasia and positively affects vascular remodeling in the rabbit balloon injury model. Catheter Cardiovasc Interv. 2001 Oct;54(2):247-56.