Details of the Drug

General Information of Drug (ID: DMMAQJ7)

Drug Name
CAR-T cells targeting Mesothelin
Indication
Disease Entry ICD 11 Status REF
Cervical cancer 2C77.0 Phase 1/2 [1]
Lung cancer 2C25.0 Phase 1/2 [2]
Drug Type
CAR T Cell Therapy
Cross-matching ID
TTD ID
D05FUP
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Mesothelin (MSLN) TT4RXME MSLN_HUMAN CAR-T-Cell-Therapy [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Cervical cancer
ICD Disease Classification 2C77.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Mesothelin (MSLN) DTT MSLN 2.86E-20 3.98 6.12
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03356795) Intervention of CAR-T Against Cervical Cancer
2 ClinicalTrials.gov (NCT03356808) Antigen-specific T Cells Against Lung Cancer