Details of the Drug

General Information of Drug (ID: DMMFLXN)

Drug Name

AD-452

Synonyms

RS(+)-mefloquine; (+)-erythro-mefloquine

Indication

Disease Entry	ICD 11	Status	REF
Rheumatoid arthritis	FA20	Phase 2	[1]
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Structure

3D Structure is Not Available

3D MOL

2D MOL

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cytokine receptor unspecific (CRF)	TTXM6JN	NOUNIPROTAC	Modulator	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT00141934) A Multicentre Trial to Determine the Efficacy of AD 452 in RA Subjects.. U.S. National Institutes of Health.
2	Detection of apoptosis by RT-PCR array in mefloquine-induced cochlear damage. Journal of Otology Volume 6, Issue 1, June 2011, Pages 1-9.