General Information of Disease (ID: DISTSB4J)

Disease Name Rheumatoid arthritis
Synonyms
rheumatoid arthritis, susceptibility to; atrophic arthritis; rheumatoid arthritis, progression of; arthritis, rheumatoid; RA; rheumatoid arthritis; autoimmune arthritis; arthritis or polyarthritis, rheumatic
Disease Class FA20: Rheumatoid arthritis
Definition
A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.
Disease Hierarchy
DIST1YEL: Arthritis
DIS77ACK: Rheumatic disorder
DISSDQ8O: Autoimmune disorder of musculoskeletal system
DISTSB4J: Rheumatoid arthritis
ICD Code
ICD-11
ICD-11: FA20
ICD-9
ICD-9: 729
Expand ICD-9
729
Disease Identifiers
MONDO ID
MONDO_0008383
MESH ID
D001172
UMLS CUI
C0003873
OMIM ID
180300
MedGen ID
2078
HPO ID
HP:0001370
Orphanet ID
284130
SNOMED CT ID
69896004

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 50 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Abatacept DMSA8RU Approved NA [1]
Adalimumab DMQMV1B Approved Antibody [2]
Alclofenac DM8CY9X Approved Small molecular drug [3]
Anakinra DMU8KOD Approved NA [4]
Baricitinib DM4ONW5 Approved Small molecular drug [5]
Belumosudil DM548TK Approved NA [6]
Betamethasone DMAHJEF Approved Small molecular drug [7]
Canakinumab DM8HLO5 Approved Antibody [8]
Careram DM2VU92 Approved Small molecular drug [9]
Celecoxib DM6LOQU Approved Small molecular drug [10]
Certolizumab DM5CL9Z Approved Monoclonal antibody [11]
Cortisone Acetate DMG8K57 Approved Small molecular drug [12]
Denosumab DMNI0KO Approved Antibody [13]
Dexamethasone DMMWZET Approved Small molecular drug [14]
Dimethyl Sulfoxide DMX3ZFP Approved Small molecular drug [3]
Etofenamate DMZLO2I Approved Small molecular drug [3]
Etoricoxib DM6A4NW Approved Small molecular drug [15]
Fenoprofen DML5VQ0 Approved Small molecular drug [16]
Flurbiprofen DMGN4BY Approved Small molecular drug [17]
Fostamatinib DM6AUHV Approved Small molecular drug [18]
Gold sodium thiomalate DMKHHT1 Approved Small molecular drug [3]
Golimumab DMHZV7X Approved Antibody [19]
Hydrocortisone DMGEMB7 Approved Small molecular drug [20]
Indomethacin DMSC4A7 Approved Small molecular drug [3]
Infliximab DMH7OIA Approved Antibody [21]
Inosine pranobex DM2P6R0 Approved Small molecular drug [3]
Methotrexate DM2TEOL Approved Small molecular drug [22]
Methylprednisolone DM4BDON Approved Small molecular drug [3]
Niflumic Acid DMJ3I1Q Approved Small molecular drug [23]
Ofatumumab DM295PR Approved Antibody [24]
OM-89 DMG5EHN Approved NA [3]
Oxaprozin DM9UB0P Approved Small molecular drug [3]
Penicillamine DM40EF6 Approved Small molecular drug [25]
Prednisone DM2HG4X Approved Small molecular drug [26]
Salicyclic acid DM2F8XZ Approved Small molecular drug [27]
Salsalate DM13P4C Approved Small molecular drug [3]
Sarilumab DMOGNXY Approved Monoclonal antibody [3]
Secukinumab DMYXT2U Approved Monoclonal antibody [28]
Siponimod DM2R86O Approved Small molecular drug [29]
Sirolimus DMGW1ID Approved Small molecular drug [30]
Sulfasalazine DMICA9H Approved Small molecular drug [31]
Sulindac DM2QHZU Approved Small molecular drug [32]
Tenoxicam DMVAZP9 Approved Small molecular drug [33]
Teriflunomide DMQ2FKJ Approved Small molecular drug [34]
Tocilizumab DM7J6OR Approved Monoclonal antibody [35]
Tofacitinib DMBS370 Approved Small molecular drug [36]
Tolmetin DMWUIJE Approved Small molecular drug [37]
Triamcinolone DM98IXF Approved Small molecular drug [38]
Upadacitinib DM32B5U Approved NA [39]
Vamorolone DM047HI Approved NA [29]
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⏷ Show the Full List of 50 Drug(s)
This Disease is Treated as An Indication in 170 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
ABP 501 DM2J4YB Phase 3 Antibody [40]
ABP 798 DMSX35S Phase 3 NA [29]
ABT-874 DMYHSO2 Phase 3 NA [11]
ASP-015K DMZ1UOI Phase 3 Small molecular drug [29]
Atacicept DM8GFEV Phase 3 NA [41]
BI 695501 DMBS0QU Phase 3 NA [42]
BI-695500 DMT0NTL Phase 3 NA [29]
Cartistem DM11TX7 Phase 3 NA [43]
CEP-41750 DMPR0LU Phase 3 NA [44]
CHS-0214 DM11R0Z Phase 3 NA [29]
Cilengitide DMEAOZ0 Phase 3 Small molecular drug [45]
CIPEMASTAT DM803GL Phase 3 Small molecular drug [46]
CPL-7075 DM62E7C Phase 3 Small molecular drug [29]
Flobufen DMPSG4D Phase 3 Small molecular drug [47]
GP-2017 DMR670F Phase 3 NA [29]
GP2013 DMZB45J Phase 3 NA [29]
GS-5745 DMP8MDW Phase 3 NA [29]
IB-MECA DM9G5XD Phase 3 Small molecular drug [29]
MK-8808 DMT8IAJ Phase 3 NA [48]
Nipocalimab DM0622O Phase 3 Monoclonal antibody [49]
Nipocalimab? DM0DYAX Phase 3 Monoclonal antibody [49]
Olokizumab DM4Z9QI Phase 3 Monoclonal antibody [29]
PF-06410293 DM2GF14 Phase 3 Antibody [29]
PF-06438179 DMM4C95 Phase 3 NA [29]
RAVAX DMGJ8ES Phase 3 NA [50]
Resveratrol DM3RWXL Phase 3 Small molecular drug [29]
SA-237 DM7F2VG Phase 3 NA [51]
Sirukumab DMK8AQP Phase 3 Monoclonal antibody [52]
Sivelestat DM6BZCV Phase 3 Small molecular drug [29]
Spermidine DMVJNFI Phase 3 Small molecular drug [29]
STI-002 DMHI77P Phase 3 NA [29]
Tenidap DMHQRYE Phase 3 Small molecular drug [53]
Vanadate DMQL0KF Phase 3 Small molecular drug [29]
Varespladib methyl DMLIMEA Phase 3 Small molecular drug [54]
LY3090106 DM0DLGO Phase 2/3 Antibody [55]
VX-509 DM2U3MX Phase 2/3 Small molecular drug [56]
CreaVax-RA DMT7URP Phase 2a NA [57]
RhuDex DMGM1IR Phase 2a NA [41]
VX-702 DMKJDR6 Phase 2a Small molecular drug [58]
A223 DMHRS2O Phase 2 Small molecule [59]
ABBV-154 DMVWLET Phase 2 Antibody drug conjugate [60]
ABT-122 DM23UQ9 Phase 2 Monoclonal antibody [61]
AD-452 DMMFLXN Phase 2 NA [62]
ADL-5859 DMDQH9A Phase 2 Small molecular drug [63]
AK-106-001616 DM6VA14 Phase 2 NA [64]
ALD-518 DMPWSBL Phase 2 NA [65]
ALX-0061 DMO1VHC Phase 2 Antibody [29]
AMG-714 DM1T3KQ Phase 2 Antibody [11]
AMG0714 DM77N7C Phase 2 NA [66]
Anti-LT alpha DMQ58YH Phase 2 Antibody [67]
Apratastat DM8W4N9 Phase 2 Small molecular drug [68]
APX-001 DMAIJC9 Phase 2 NA [69]
Baminercept DMSZOXQ Phase 2 NA [70]
BI 655064 DMF86P2 Phase 2 Antibody [71]
BIIB 023 DM9OXEJ Phase 2 NA [72]
BMS-817399 DMT8L6P Phase 2 NA [73]
BMS-945429 DMCIQEP Phase 2 NA [74]
BMS-986142 DMZB8AJ Phase 2 NA [29]
Branebrutinib DM97I5L Phase 2 Small molecule [75]
BT-016 DMTH56Y Phase 2 NA [76]
CCX-354 DMSHV9C Phase 2 NA [29]
CDP-6038 DM3YB2C Phase 2 NA [65]
CDP323 DMXYLTI Phase 2 Small molecular drug [11]
Cenplacel-L DMVL9KP Phase 2 NA [77]
Cevidoplenib DM9QU5G Phase 2 Small molecule [78]
CFZ533 DM1TWIE Phase 2 NA [79]
CH-4051 DMLQRYH Phase 2 NA [80]
CNT0-1959 DMOR8SY Phase 2 Antibody [81]
CNTO-6785 DM6RQXB Phase 2 Antibody [82]
Dazodalibep DM7YII9 Phase 2 NA [83]
DE-098 DM5XT3G Phase 2 Antibody [84]
EQ121 DMJN8UW Phase 2 Small molecule [85]
F-8-IL-10 fusion protein DMBFPO1 Phase 2 NA [29]
FK-3311 DML5AE4 Phase 2 Small molecular drug [86]
Fosbretabulin DMKSI2I Phase 2 Small molecular drug [87]
GLPG-0634 DMPHCDL Phase 2 Small molecular drug [88]
GS-4059 DMHQV6R Phase 2 NA [29]
GS-5718 DMRKU0L Phase 2 Small molecule [89]
GS-9876 DM9Q2B6 Phase 2 NA [29]
GSK2982772 DM7HNFV Phase 2 NA [29]
GSK315234 DMVL1WZ Phase 2 NA [90]
GSK3196165 DMEXKF4 Phase 2 NA [29]
IMO-8400 DMDPNCJ Phase 2 NA [29]
IRL201805 DM0S9C3 Phase 2 NA [91]
JNJ-38518168 DM9UMIO Phase 2 NA [92]
K-832 DMMSTCF Phase 2 Small molecular drug [11]
KB002/003 DM60G5O Phase 2 NA [93]
KPL-404 DMQJODL Phase 2 Antibody [94]
LX2931 DMLA8H3 Phase 2 Small molecular drug [95]
M2951 DMC5MQD Phase 2 NA [29]
Mavrilimumab DMMVFRC Phase 2 Antibody [96]
Meninge ACYW DMJCA5X Phase 2 NA [97]
MGCD-290 DMAJV1J Phase 2 Small molecular drug [98]
MK-8457 DMIDVZ3 Phase 2 NA [99]
MPC-300-IV DMRWDG9 Phase 2 NA [29]
MRC-375 DMKG9EW Phase 2 NA [100]
NN8555 DM3IEHP Phase 2 NA [101]
NN8765 DMCFPBE Phase 2 NA [102]
NNC-0151-0000-0000 DMU3KOH Phase 2 Antibody [103]
ONO-4641 DMLUM3Y Phase 2 NA [104]
Ozoralizumab DMFCL3E Phase 2 Monoclonal antibody [106]
PD-360324 DM6F5EV Phase 2 NA [107]
Pegsunercept DMTDANB Phase 2 NA [108]
Peresolimab DMYT8E0 Phase 2 Monoclonal antibody [109]
PF-04171327 DM5G3B0 Phase 2 Small molecular drug [110]
PF-06823859 DM8C1H4 Phase 2 NA [111]
PG-760564 DMSUMNC Phase 2 NA [112]
Piclamilast DMYL7VR Phase 2 Small molecular drug [113]
PRALNACASAN DM73UTG Phase 2 Small molecular drug [114]
PTC299 DMP9TKE Phase 2 Small molecular drug [115]
QAL964 DMK3V4O Phase 2 NA [116]
Rabeximod DMFPHYI Phase 2 NA [117]
Rimacalib DMSC7TN Phase 2 Small molecular drug [118]
SAN-300 DMP5Z9N Phase 2 NA [119]
SBI-087 DMSUQFJ Phase 2 NA [120]
SR-31747 DMQSN7B Phase 2 Small molecular drug [121]
SSR-180575 DMA0QZH Phase 2 Small molecular drug [122]
SSR-240612 DMFNZPY Phase 2 Small molecular drug [123]
STA-5326 DMH4C3M Phase 2 Small molecular drug [124]
TAK-715 DMZKPI8 Phase 2 Small molecular drug [125]
TAK-783 DMK64PY Phase 2 NA [126]
VAY736 DML2CPW Phase 2 Antibody [29]
Vidofludimus DM0POWG Phase 2 Small molecular drug [127]
Vobarilizumab DM9KNJT Phase 2 Antibody [128]
VX-745 DMJAEG6 Phase 2 Small molecular drug [129]
Xmab 5871 DMLIPY1 Phase 2 NA [130]
Zunsemetinib DMNFNK7 Phase 2 Small molecule [131]
[L/D]-aminopterin DMK9X88 Phase 2 NA [132]
ART621 DMI17NX Phase 1/2 NA [133]
BIO-300 DMJ7NVI Phase 1/2 NA [134]
Cx-611 DML4B3D Phase 1/2 NA [135]
PRTX-100 DMF2XCC Phase 1/2 NA [29]
ABBV-257 DMCZI8L Phase 1 NA [29]
Aminoguanidine DMJQDUC Phase 1 Small molecular drug [136]
ARG301 DM6EA4G Phase 1 NA [137]
ASP2408 DMUGZKI Phase 1 NA [138]
ASP5094 DMCYA8C Phase 1 NA [29]
AVE1701 DMJY35M Phase 1 NA [11]
AXS-06 DMSMZMU Phase 1 NA [139]
AZD9567 DMAXHC0 Phase 1 NA [29]
BF-389 DMHELFU Phase 1 Small molecular drug [140]
BMS-986104 DMZ4WMT Phase 1 NA [29]
BX-U001 DM65N6Y Phase 1 Cell therapy [141]
Cadherin-11 DM5PMQ7 Phase 1 NA [142]
EVT 401 DMOG8IE Phase 1 NA [143]
Gerilimzumab DMA9UX2 Phase 1 NA [29]
GSK-1827771 DMA41JD Phase 1 Antibody [144]
GSK3117391 DMQZSXD Phase 1 Small molecular drug [145]
HM71224 DME4D7H Phase 1 Small molecular drug [146]
IA-14069 DM15SXV Phase 1 Small molecule [147]
JNJ-67484703 DMYSCXF Phase 1 NA [148]
LABP-104 DMMYYB9 Phase 1 Small molecule [149]
MEDI4920 DME7BMT Phase 1 NA [29]
MEDI5117 DM3IJQ5 Phase 1 NA [150]
MORAb-022 DMM7TBO Phase 1 Antibody [29]
NCX-1015 DMKJRQS Phase 1 NA [151]
ONS-3010 DMVMZ8M Phase 1 NA [29]
ORTD-1 DMR1PQI Phase 1 Small molecule [152]
PF-05230905 DM7OC9K Phase 1 NA [153]
RG6125 DMX8YO1 Phase 1 NA [29]
RPI-78M DMXKFOQ Phase 1 NA [154]
RX-10001 DMQZ3T4 Phase 1 NA [155]
Sc Veltuzumab DM2S8W3 Phase 1 Monoclonal antibody [156]
SCH-900117 DM7A6R5 Phase 1 NA [157]
SKI-O-703 DMTSKXR Phase 1 NA [29]
TAK-020 DM6OKH4 Phase 1 NA [29]
VEL-0230 DMDSC63 Phase 1 Small molecular drug [158]
VGX-1027 DMM1N5C Phase 1 Small molecular drug [159]
VI7734 DMWKFRC Phase 1 NA [111]
AZ-4217 DMGPTFL Clinical trial Small molecular drug [160]
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⏷ Show the Full List of 170 Drug(s)
This Disease is Treated as An Indication in 2 Drugs in Phase 2 Trial
Drug Name Drug ID Highest Status Drug Type REF
Clazakizumab DM6ZOUV Phase 2 Trial Monoclonal antibody [29]
Otilimab DM1AQLW Phase 2 Trial Monoclonal antibody [105]
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This Disease is Treated as An Indication in 1 Patented Agent(s)
Drug Name Drug ID Highest Status Drug Type REF
PMID27998201-Compound-9 DM1JOZN Patented Small molecular drug [161]
------------------------------------------------------------------------------------
This Disease is Treated as An Indication in 69 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Amiprilose DM8JD3O Discontinued in Preregistration Small molecular drug [162]
Nerelimomab DM1QAGC Discontinued in Phase 3 Monoclonal antibody [163]
AMG 108 DMMUS8X Discontinued in Phase 2 Small molecular drug [164]
AnergiX.RA DM869ZM Discontinued in Phase 2 NA [165]
Apricoxib DMR3Q82 Discontinued in Phase 2 Small molecular drug [166]
BR3-Fc DMFN1WI Discontinued in Phase 2 NA [167]
Camobucol DMS3ECJ Discontinued in Phase 2 Small molecular drug [168]
CBF-BS2 DM2FAH0 Discontinued in Phase 2 NA [169]
CP-195543 DM1OSUR Discontinued in Phase 2 Small molecular drug [170]
Fontolizumab DMEH6LV Discontinued in Phase 2 Antibody [11]
GLPG-0259 DMC87DR Discontinued in Phase 2 NA [171]
HR325 DM51GZS Discontinued in Phase 2 Small molecular drug [172]
IDEC-151 DMILUHA Discontinued in Phase 2 Antibody [173]
INCB47986 DMNRQA9 Discontinued in Phase 2 NA [174]
ISIS 104838 DMURWPH Discontinued in Phase 2 Antisense drug [175]
IX207-887 DM4TE8R Discontinued in Phase 2 NA [176]
KC706 DMBX6C7 Discontinued in Phase 2 NA [177]
MLN3897 DMRA3EZ Discontinued in Phase 2 NA [11]
MP-435 DMMKHGN Discontinued in Phase 2 NA [178]
NN8209 DM2TDE7 Discontinued in Phase 2 NA [179]
PAMAPIMOD DM9SYUT Discontinued in Phase 2 Small molecular drug [180]
PRO-515 DMV1ZQO Discontinued in Phase 2 NA [181]
S-2474 DMMSZ1A Discontinued in Phase 2 Small molecular drug [182]
SC-106 DMTZ7E4 Discontinued in Phase 2 Small molecular drug [183]
T-5224 DMD3CUJ Discontinued in Phase 2 Small molecular drug [184]
AD-121 DMB8XJM Discontinued in Phase 1/2 NA [185]
AME-527 DMR8XEN Discontinued in Phase 1/2 Antibody [186]
AVE-9940 DMIB3AT Discontinued in Phase 1 NA [187]
AZD-2315 DMG9HM8 Discontinued in Phase 1 NA [188]
AZD-6703 DM9KLD3 Discontinued in Phase 1 Small molecular drug [189]
AZD-7140 DMX63W1 Discontinued in Phase 1 NA [190]
AZD-8309 DMW6IUB Discontinued in Phase 1 NA [191]
AZD8566 DMIYEZG Discontinued in Phase 1 NA [192]
C-5997 DM0G88H Discontinued in Phase 1 Small molecular drug [193]
CI-972 DM9ZBO0 Discontinued in Phase 1 Small molecular drug [194]
IL-18BP DMRSJ49 Discontinued in Phase 1 NA [195]
NN8210 DM8Z5VH Discontinued in Phase 1 NA [196]
PF-251802 DM2V7WH Discontinued in Phase 1 NA [197]
PF-4629991 DMNLAU7 Discontinued in Phase 1 NA [198]
PF-755616 DMWNV6C Discontinued in Phase 1 NA [199]
R-1487 DM7WPI0 Discontinued in Phase 1 Small molecular drug [200]
R1295 DMT8V9G Discontinued in Phase 1 Small molecular drug [11]
Roquinimex DMMK42O Discontinued in Phase 1 Small molecular drug [201]
SC-57666 DMIVRWS Discontinued in Phase 1 Small molecular drug [202]
AZD-0275 DMJH7IX Terminated NA [207]
AZD-0902 DMS7INR Terminated NA [208]
AZD-6942 DMZ90OV Terminated NA [209]
AZD5672 DMQUX28 Terminated Small molecular drug [210]
CI-986 DMI0TD8 Terminated Small molecular drug [211]
D-5410 DMXHN6U Terminated NA [212]
DPC-333 DM4JBQD Terminated Small molecular drug [213]
FR-123826 DM0582D Terminated NA [214]
GDC-0834 DMOAURL Terminated Small molecular drug [215]
NOX-200 DM78P4X Terminated Small molecular drug [216]
NPC-17923 DMD01GK Terminated Small molecular drug [217]
PXS-2076 DM1AXZ6 Terminated NA [218]
RO-319790 DML3NEU Terminated Small molecular drug [219]
RP-54745 DMVUP8F Terminated Small molecular drug [220]
RPR 200765A DM1U0TB Terminated Small molecular drug [221]
S-16276-1 DMHF2HS Terminated NA [222]
SAN-18 DM66J4T Terminated NA [223]
SDZ-224-015 DMY1KE8 Terminated NA [224]
SKF-104351 DM8MWFZ Terminated Small molecular drug [225]
SR-26831 DM1GKTS Terminated Small molecular drug [226]
TM-31 DMWRX6O Terminated NA [227]
VE-16084 DMHG70W Terminated NA [228]
WY-28342 DMAG86C Terminated NA [229]
WY-48989 DMGJNQW Terminated Small molecular drug [230]
YM-26734 DMEHAI2 Terminated Small molecular drug [231]
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⏷ Show the Full List of 69 Drug(s)
This Disease is Treated as An Indication in 6 Preclinical Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
GP2015 DMVYFTQ Application submitted NA [29]
CLIK-148 DM0BHL8 Preclinical Small molecular drug [203]
CLIK-181 DMXKN6R Preclinical Small molecular drug [203]
MCP-1 DMYEFKH Preclinical NA [204]
Romazarit DMZOUX4 Preclinical Small molecular drug [205]
SR1555 DMZV9JX Preclinical Small molecular drug [206]
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⏷ Show the Full List of 6 Drug(s)
This Disease is Treated as An Indication in 32 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
ADR58 DMQBCPK Investigative Aptamer [232]
Ankinara DMZKC7S Investigative NA [204]
Anti-CD40-XTEN DMGZM6V Investigative NA [233]
Anti-CD97 mab DMPJJ6K Investigative Monoclonal antibody [69]
Arthromir DM06780 Investigative NA [69]
AVX-002 DMPG926 Investigative NA [69]
BFPT-16864 DM46LXH Investigative NA [69]
CAT-2200 DMWHP52 Investigative Antibody [234]
CEL-2000 DM0CN4O Investigative NA [69]
CIGB-55 DME2DF2 Investigative NA [69]
CIGB-814 DM0PCTV Investigative NA [69]
CTLA-4-XTEN DMKEIAS Investigative NA [235]
Dendritic cell-based immunotherapy DMVOR1V Investigative NA [69]
DMARDs DM7LLQI Investigative NA [69]
DWJ-425 DMG67AR Investigative NA [69]
ETP-46321 DMO2PY8 Investigative Small molecular drug [236]
FHT-401 DMV3TC7 Investigative NA [69]
FKB327 DML5QF9 Investigative NA [29]
FM-201 DMOI3OY Investigative NA [69]
HL-1020 DMOFTV4 Investigative NA [69]
IG-AI-025 DMQZGCG Investigative NA [69]
Nano-steroid DM3G0LL Investigative NA [69]
NM-2014 DM6RA20 Investigative NA [237]
NM-9405 DMKMBSJ Investigative Antibody [237]
ODN-1411 DM0GVZO Investigative Oligonucleotide [238]
ROSMARINIC ACID DMQ6SJT Investigative Small molecular drug [239]
TCH-013 DMZY17R Investigative NA [69]
TENOSAL DMMLSZ4 Investigative Small molecular drug [240]
TNFcept DMAGI7K Investigative NA [241]
TNFmab DM4T0ZF Investigative Antibody [241]
TX-RAD DM59IZI Investigative NA [69]
UR-5269 DMHA0R2 Investigative NA [69]
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⏷ Show the Full List of 32 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 691 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ABCC2 TTFLHJV Limited Biomarker [243]
ABCG2 TTIMJ02 Limited Biomarker [243]
AGER TTMO9HF Limited Biomarker [244]
ALOX12 TT12ABZ Limited Altered Expression [245]
AMACR TTLN1AP Limited Altered Expression [246]
AMD1 TTBFROQ Limited Biomarker [247]
APCS TTB7VAT Limited Biomarker [248]
APOA2 TTGQA9W Limited Biomarker [249]
ARG2 TTV1AG6 Limited Altered Expression [250]
ASIC1 TTRJYB6 Limited Biomarker [251]
ATP1A1 TTWK8D0 Limited Altered Expression [252]
BIRC2 TTQ5LRD Limited Biomarker [253]
BLK TTNDSC3 Limited Biomarker [254]
BMP6 TT07RIB Limited Biomarker [255]
BMX TTN2I9E Limited Biomarker [256]
BPI TTXCSDR Limited Biomarker [257]
BTK TTGM6VW Limited Biomarker [258]
CA2 TTANPDJ Limited Genetic Variation [259]
CA3 TTXUK5D Limited Biomarker [260]
CCL23 TTHAPJK Limited Altered Expression [261]
CD209 TTBXIM9 Limited Genetic Variation [262]
CD5 TTEGYK1 Limited Biomarker [263]
CD58 TT5KSBY Limited Biomarker [264]
CD9 TTZEIBV Limited Altered Expression [265]
CDKN2C TTBRUGA Limited Genetic Variation [266]
CEBPB TTUI35N Limited Biomarker [267]
CLEC6A TTQ02HK Limited Genetic Variation [268]
CMKLR1 TT4UGZL Limited Altered Expression [269]
CSE1L TTTRULD Limited Biomarker [270]
CSF2RA TT6MP2Z Limited Altered Expression [271]
CSNK1E TTA8PLI Limited Biomarker [253]
CXCL13 TT0NIZ1 Limited Altered Expression [272]
CXCR5 TTIW59R Limited Biomarker [272]
CYP3A5 TTHS0OK Limited Biomarker [273]
DCK TTJOCE4 Limited Biomarker [274]
DEK TT1NMGV Limited Genetic Variation [275]
DKK2 TTST5KX Limited Biomarker [276]
DUSP8 TTK0TF2 Limited Genetic Variation [277]
EIF2AK2 TTXEZJ4 Limited Biomarker [278]
EPHA1 TTLFZVU Limited Biomarker [279]
ERAP2 TTVGS1C Limited Altered Expression [280]
EREG TTYSB89 Limited Biomarker [281]
FCGRT TTKLPHO Limited Genetic Variation [282]
FGF4 TTCEKVZ Limited Altered Expression [283]
FGF7 TTFY134 Limited Altered Expression [284]
FPR1 TT5Y4EM Limited Genetic Variation [285]
GART TTEXB9Z Limited Biomarker [243]
GRIK4 TTQV6BO Limited Biomarker [286]
GRK5 TTTCXO0 Limited Altered Expression [287]
HDC TTV9GOF Limited Altered Expression [288]
HDGF TTKGV26 Limited Biomarker [289]
HEXA TTJI5JW Limited Altered Expression [290]
HEXB TTKIBKM Limited Altered Expression [290]
ICOSLG TTB9Z8R Limited Biomarker [291]
IFNGR2 TT13TL0 Limited Altered Expression [292]
IL11 TTGUYTR Limited Biomarker [293]
IL1R2 TT51DEV Limited Altered Expression [294]
IRF3 TTYR7OH Limited Altered Expression [295]
IRF8 TTHUBNK Limited Biomarker [263]
ITPR2 TTK9OV3 Limited Biomarker [296]
LCAT TTGZ91P Limited Biomarker [249]
LILRB2 TTHC6XU Limited Altered Expression [297]
LPAR3 TTE2YJR Limited Biomarker [298]
LRP6 TTSXOWE Limited Altered Expression [276]
LYZ TTAOZBW Limited Biomarker [299]
MAPK9 TT3IVG2 Limited Biomarker [300]
MARCKS TTHRM39 Limited Biomarker [301]
MASP2 TTR01E9 Limited Genetic Variation [302]
MIA TT5HNVS Limited Biomarker [303]
MMP14 TTJ4QE7 Limited Biomarker [304]
MMP15 TTNSTO3 Limited Biomarker [305]
MMP17 TTVSZKN Limited Biomarker [306]
MMP8 TTGA1IV Limited Genetic Variation [307]
MUC17 TTVO0JU Limited Altered Expression [308]
NEDD9 TT1UREA Limited Biomarker [309]
NELL1 TT7H4BF Limited Biomarker [310]
NPPB TTY63XT Limited Altered Expression [311]
NTN1 TT0AH4L Limited Biomarker [312]
ODC1 TTUMGNO Limited Altered Expression [313]
OPRK1 TTQW87Y Limited Altered Expression [314]
PCSK1 TTED9LZ Limited Altered Expression [315]
PDE4D TTSKMI8 Limited Biomarker [316]
PDGFD TTSN0GA Limited Biomarker [317]
PIM2 TT69J2Z Limited Biomarker [318]
PKN1 TTSL41O Limited Altered Expression [319]
PLD1 TT3T17P Limited Altered Expression [320]
PPM1A TTLA7IX Limited Biomarker [321]
PRCP TTTJZ4M Limited Biomarker [322]
PRDX5 TTLPJWH Limited Biomarker [323]
PRKCH TTONI0R Limited Genetic Variation [324]
PSMB5 TT68GPI Limited Genetic Variation [325]
PSMB6 TT8EPLT Limited Genetic Variation [326]
PSMB8 TTEAD9J Limited Genetic Variation [327]
PSMB9 TTOUSTQ Limited Genetic Variation [327]
PTGER2 TT1ZAVI Limited Biomarker [328]
PTGER4 TT79WV3 Limited Biomarker [329]
PTGS1 TT8NGED Limited Biomarker [330]
PTPN14 TTNIR6C Limited Altered Expression [331]
PTPN2 TTY8PUS Limited Genetic Variation [324]
PTPRC TTUS45N Limited Biomarker [332]
QPCT TTJ7YTV Limited Biomarker [333]
RARG TT1Q3IE Limited Altered Expression [334]
RGS12 TTP9AV7 Limited Altered Expression [335]
RPS6KA5 TTYXEPL Limited Biomarker [336]
RXRA TT6PEUO Limited Biomarker [337]
S1PR2 TTVSMOH Limited Biomarker [338]
S1PR3 TTDYP7I Limited Biomarker [338]
SEMA4D TT5UT28 Limited Altered Expression [339]
SFRP4 TTX8I1Y Limited Biomarker [340]
SIRPA TTBRJS9 Limited Biomarker [341]
SMAD7 TT0J32Z Limited Biomarker [342]
SPHK2 TTCN0M9 Limited Biomarker [343]
STC2 TT4EFTR Limited Biomarker [344]
TDGF1 TTN7HMG Limited Altered Expression [345]
TF TT8WXAV Limited Altered Expression [346]
TFF1 TTNOJIZ Limited Altered Expression [347]
TGFB3 TTWOMY8 Limited Biomarker [348]
THBD TTAPV67 Limited Biomarker [349]
TNFRSF4 TTL31H0 Limited Biomarker [350]
TPH2 TT3KLDP Limited Biomarker [351]
TPT1 TT3PTB6 Limited Biomarker [352]
TRPC1 TTA76X0 Limited Altered Expression [353]
TRPC5 TT32NQ1 Limited Altered Expression [353]
TRPM3 TTO3TD8 Limited Biomarker [354]
TRPV2 TTBECWA Limited Biomarker [355]
TXNIP TTTLDZK Limited Biomarker [301]
TYK2 TTBYWP2 Limited Genetic Variation [356]
TYMS TTP1UKZ Limited Altered Expression [357]
UGCG TTPHEX3 Limited Altered Expression [358]
VCAM1 TTHCEF6 Limited Biomarker [359]
VIPR1 TTCL30I Limited Altered Expression [360]
ALOX5 TTSJ6Q4 Disputed Altered Expression [361]
ARG1 TT7ZQEV Disputed Biomarker [362]
ARRB1 TTMVD4A Disputed Biomarker [363]
ASPA TT6TLZP Disputed Biomarker [364]
BRD3 TTHE657 Disputed Biomarker [365]
C3AR1 TTI6B3F Disputed Biomarker [366]
CYSLTR1 TTGKOY9 Disputed Biomarker [367]
EGLN1 TT9ISBX Disputed Biomarker [368]
ESRRB TTKF0XS Disputed Altered Expression [369]
F10 TTCIHJA Disputed Biomarker [370]
HDAC5 TTUELN5 Disputed Biomarker [371]
IL25 TTVMO5W Disputed Altered Expression [372]
LAG3 TTNVXAW Disputed Biomarker [373]
LCK TT860QF Disputed Biomarker [374]
LYVE1 TTG8DNU Disputed Altered Expression [375]
MCAM TTHRE05 Disputed Altered Expression [376]
MSMB TTYH1ZK Disputed Altered Expression [377]
MTA1 TTO4HUS Disputed Biomarker [378]
NCF1 TTZ4JC3 Disputed Biomarker [379]
PTPRJ TTWMKXP Disputed Altered Expression [380]
SPHK1 TTOHFIY Disputed Altered Expression [381]
TEC TT1ZV49 Disputed Biomarker [332]
ADORA2A TTM2AOE moderate Genetic Variation [382]
AIF1 TT12MEP moderate Biomarker [383]
ASRGL1 TT4WT91 moderate Altered Expression [384]
ATIC TT9NVXQ moderate Genetic Variation [385]
BGN TT0JPVF moderate Altered Expression [386]
BMP4 TTD3BSX moderate Biomarker [387]
C3 TTJGY7A moderate Biomarker [364]
C5 TTKANGO moderate Genetic Variation [388]
C9orf72 TTA4SHR moderate Genetic Variation [389]
CD22 TTM6QSK moderate Biomarker [390]
CXCL2 TTZF0K2 moderate Altered Expression [391]
CYP26A1 TTD7Q0R moderate Altered Expression [392]
DNAJB1 TTPXAWS moderate Biomarker [393]
DUSP1 TTG8HIM moderate Biomarker [394]
EBI3 TTJF68X moderate Biomarker [395]
EIF4EBP1 TTKGEBL moderate Altered Expression [396]
FASLG TTO7014 moderate Genetic Variation [397]
FKBP5 TT0J5KQ moderate Altered Expression [398]
FLT4 TTDCBX5 moderate Biomarker [399]
GATA3 TT45KOB moderate Genetic Variation [324]
GGH TTZJRL0 moderate Genetic Variation [400]
GPX1 TTYAHBP moderate Altered Expression [401]
GRK2 TTAZ3MN moderate Biomarker [402]
HSD11B1 TTN7BL9 moderate Biomarker [403]
ID1 TTBXVDE moderate Biomarker [404]
IGFBP1 TTCJTWF moderate Altered Expression [405]
IKZF3 TTCZVFZ moderate Biomarker [406]
IL1RAP TTWS50K moderate Biomarker [407]
KCNMA1 TTE87WJ moderate Biomarker [408]
KDM6B TTDIJUQ moderate Biomarker [409]
KNG1 TTDJ4MY moderate Altered Expression [410]
MMP10 TTXLEG7 moderate Biomarker [301]
NLRC5 TTWZC78 moderate Altered Expression [411]
NOX4 TTQRBSJ moderate Altered Expression [412]
NR4A1 TTMXE2Q moderate Biomarker [413]
PAK1 TTFN95D moderate Biomarker [414]
PAM TTF4ZPC moderate Biomarker [415]
PDE2A TTJGW1Z moderate Genetic Variation [416]
PDE7A TT1BC3A moderate Altered Expression [417]
PLAUR TTNOSTX moderate Biomarker [418]
PPARGC1B TTKSQ3W moderate Altered Expression [419]
PRKCQ TT1MS7X moderate Biomarker [420]
RBPJ TT72D4Z moderate Altered Expression [421]
RHBDF2 TTH1ZOP moderate Biomarker [422]
RORC TTGV6LY moderate Biomarker [396]
SHCBP1 TTZ9WGL moderate Biomarker [423]
SLC40A1 TT6Y1PG moderate Genetic Variation [424]
SPRY1 TT0PSN6 moderate Altered Expression [425]
STS TTHM0R1 moderate Biomarker [426]
TBX21 TTNF9PH moderate Altered Expression [427]
THBS1 TTKI0H1 moderate Biomarker [428]
TLR9 TTSHG0T moderate Biomarker [429]
TNFRSF18 TTG6LA7 moderate Altered Expression [430]
TNNC1 TT8RDXP moderate Biomarker [431]
TREM2 TTQRMSJ moderate Altered Expression [432]
VEGFD TTOM5H4 moderate Altered Expression [423]
VIP TTGTWLF moderate Altered Expression [433]
ABCC3 TTVLG21 Strong Biomarker [243]
ABCC4 TTUEAFL Strong Genetic Variation [434]
ABCC8 TTP835K Strong Biomarker [435]
ACKR3 TTRQJTC Strong Altered Expression [436]
ACR TTAHE2N Strong Biomarker [437]
ACTG1 TTGAZF9 Strong Biomarker [438]
ADA TTLP57V Strong Biomarker [439]
ADAM10 TTVXEGU Strong Altered Expression [440]
ADAM17 TT6AZXG Strong Biomarker [422]
ADAM8 TTQWYMD Strong Biomarker [441]
ADAMTS4 TTYG6BU Strong Biomarker [442]
ADAMTS5 TTXSU2Y Strong Biomarker [443]
ADM TTV14YH Strong Biomarker [244]
ADRB2 TTG8ZWP Strong Biomarker [444]
ADRB3 TTMXGCW Strong Genetic Variation [445]
AGPAT1 TTPL1TK Strong Genetic Variation [446]
AICDA TTKRTP6 Strong Altered Expression [447]
AIMP2 TTXWHGF Strong Biomarker [448]
ALCAM TT2AFT6 Strong Biomarker [449]
ALOX15 TTN9T81 Strong Biomarker [450]
ALOX5AP TTDMBF5 Strong Biomarker [451]
AMOT TTI48OS Strong Altered Expression [452]
ANG TTURHFP Strong Altered Expression [453]
ANGPT1 TTWNQ1T Strong Altered Expression [454]
ANGPT2 TTKLQTJ Strong Genetic Variation [455]
ANGPTL4 TTWALY5 Strong Altered Expression [456]
ANXA1 TTUCK4B Strong Biomarker [457]
AOC1 TTM3B5R Strong Biomarker [458]
APLN TT87D3J Strong Biomarker [459]
APOB TTN1IE2 Strong Biomarker [460]
AQP1 TTSF1KH Strong Biomarker [461]
AQP9 TTQEI32 Strong Altered Expression [462]
ARRB2 TT8SO2I Strong Biomarker [463]
ASIC3 TTLGDIS Strong Biomarker [464]
ATAT1 TTWUHQ1 Strong Genetic Variation [327]
BAK1 TTFM7V0 Strong Biomarker [465]
BCL2A1 TTGT9C7 Strong Biomarker [466]
BDKRB2 TTGY8IW Strong Biomarker [467]
BRS3 TTKYEPM Strong Biomarker [468]
BSG TT5UJWD Strong Biomarker [469]
BTLA TTER58P Strong Altered Expression [470]
C5AR1 TTHXFA1 Strong Biomarker [471]
CA1 TTHQPL7 Strong Biomarker [472]
CACNA1S TT94HRF Strong Biomarker [473]
CALR TTUZ7OA Strong Altered Expression [474]
CAMP TTULOB6 Strong Biomarker [475]
CASP1 TTCQIBE Strong Biomarker [476]
CASP10 TTX5HEK Strong Genetic Variation [477]
CCL17 TTMPHAE Strong Biomarker [478]
CCL20 TT2XAZY Strong Biomarker [479]
CCL22 TTBTWI1 Strong Altered Expression [480]
CCL3 TT8I4WB Strong Biomarker [481]
CCN2 TTIL516 Strong Altered Expression [482]
CCR1 TTC24WT Strong Biomarker [483]
CCR3 TTD3XFU Strong Biomarker [484]
CCR4 TT7HQD0 Strong Biomarker [485]
CCR7 TT2GIDQ Strong Biomarker [486]
CCR9 TTIPS8B Strong Biomarker [487]
CD160 TTOFEAS Strong Genetic Variation [488]
CD163 TTTZ9DE Strong Altered Expression [489]
CD19 TTW640A Strong Biomarker [490]
CD2 TTJDUNO Strong Genetic Variation [491]
CD248 TTYJWT7 Strong Altered Expression [492]
CD276 TT6CQUM Strong Altered Expression [493]
CD38 TTPURFN Strong Biomarker [494]
CD3E TTZAT79 Strong Biomarker [467]
CD4 TTN2JFW Strong Genetic Variation [495]
CD44 TTWFBT7 Strong Altered Expression [496]
CD46 TTMS7DF Strong Biomarker [497]
CD55 TT5Z9WY Strong Biomarker [498]
CD6 TTMF6KC Strong Genetic Variation [449]
CD69 TTPQE9F Strong Altered Expression [499]
CD70 TTNCIE0 Strong Altered Expression [500]
CD74 TTCMYP9 Strong Biomarker [501]
CD80 TT89Z17 Strong Biomarker [502]
CDA TTQ12RK Strong Biomarker [503]
CDK5R1 TTBYM6V Strong Biomarker [504]
CFLAR TTJZQYH Strong Altered Expression [505]
CHAT TTKYFSB Strong Biomarker [506]
CHUK TT1F8OQ Strong Altered Expression [507]
CLIC1 TT8KZG6 Strong Genetic Variation [446]
CNR2 TTMSFAW Strong Biomarker [508]
CNTFR TTT2F9E Strong Genetic Variation [327]
CNTN2 TT2Z1WB Strong Genetic Variation [509]
CPB1 TT4UJX5 Strong Biomarker [510]
CR1 TTEA8OW Strong Altered Expression [511]
CR2 TT0HUN7 Strong Biomarker [512]
CREB1 TTH4AN3 Strong Biomarker [513]
CRHR1 TT7EFHR Strong Biomarker [514]
CRHR2 TTIY658 Strong Biomarker [514]
CRK TTFEUYR Strong Biomarker [448]
CSF1 TT0IQER Strong Biomarker [515]
CSF1R TT7MRDV Strong Biomarker [516]
CSF2 TTNYZG2 Strong Altered Expression [517]
CSF3R TTC70AJ Strong Biomarker [518]
CSK TTX6F0Q Strong Altered Expression [519]
CTH TTLQUZS Strong Biomarker [409]
CTSC TT4H0V2 Strong Altered Expression [520]
CTSD TTPT2QI Strong Biomarker [467]
CTSK TTDZN01 Strong Biomarker [429]
CTSL TT36ETB Strong Biomarker [521]
CTSS TTUMQVO Strong Altered Expression [522]
CXCL1 TTLK1RW Strong Biomarker [523]
CXCL11 TTWG0RE Strong Biomarker [524]
CXCL9 TTWE5PB Strong Genetic Variation [525]
CXCR1 TTMWT8Z Strong Biomarker [526]
CXCR2 TT30C9G Strong Genetic Variation [527]
CXCR3 TT1UCIJ Strong Biomarker [524]
CXCR6 TT2BVUA Strong Altered Expression [528]
CYBB TT5T8MR Strong Biomarker [307]
CYP21A2 TTP4GLG Strong Genetic Variation [446]
DDIT4 TTVEOY6 Strong Biomarker [529]
DDR1 TTI1FPZ Strong Genetic Variation [327]
DDR2 TTU98HG Strong Biomarker [530]
DHODH TTLVP78 Strong Biomarker [531]
DICER1 TTTEOPU Strong Altered Expression [532]
DKK1 TTE3RAC Strong Altered Expression [533]
DKK3 TTY2ZV6 Strong Genetic Variation [534]
DLL1 TT9CFQD Strong Biomarker [535]
DMD TTWLFXU Strong Biomarker [536]
DNASE1 TTYWGOJ Strong Altered Expression [537]
DNMT3B TT6VZ78 Strong Genetic Variation [538]
DPEP1 TTYUENF Strong Biomarker [539]
E2F2 TT5FYX0 Strong Biomarker [540]
EBP TT4VQZX Strong Biomarker [541]
EHMT1 TTOFXD7 Strong Biomarker [542]
EHMT2 TTS6RZT Strong Genetic Variation [446]
ELAVL1 TTPC9D0 Strong Altered Expression [543]
ELK3 TT5OJMV Strong Biomarker [544]
ENPP2 TTSCIM2 Strong Altered Expression [545]
ENTPD1 TTYM8DJ Strong Genetic Variation [546]
EPHB1 TT8MDAC Strong Biomarker [544]
ETS1 TTTGPSD Strong Biomarker [530]
ETS2 TT9AH0M Strong Altered Expression [547]
F3 TT38MDJ Strong Biomarker [548]
F9 TTFEZ5Q Strong Altered Expression [549]
FADS2 TTT2VDU Strong Genetic Variation [324]
FCGR1A TTZK4I3 Strong Biomarker [550]
FGF1 TTMY81X Strong Altered Expression [551]
FGF2 TTGKIED Strong Altered Expression [552]
FGF21 TTQ916P Strong Biomarker [553]
FHL1 TTI7ENL Strong Altered Expression [554]
FLT1 TT1VAUK Strong Biomarker [555]
FN1 TTPJ921 Strong Biomarker [556]
FOLR2 TTT54CI Strong Altered Expression [557]
FOS TTOM5AU Strong Biomarker [530]
FOSL1 TTY8LZG Strong Biomarker [558]
FOXC1 TTNT3YA Strong Biomarker [559]
FPR2 TTOJ1NF Strong Biomarker [560]
FTO TTFW3BT Strong Genetic Variation [561]
FURIN TTH9WF6 Strong Altered Expression [562]
FUT4 TTNV1KZ Strong Biomarker [563]
G3BP1 TTG0R8Z Strong Biomarker [564]
GADD45B TTMDW9L Strong Genetic Variation [565]
GAS6 TT69QD2 Strong Altered Expression [566]
GCK TTDLNGZ Strong Altered Expression [567]
GDF15 TT4MXVG Strong Altered Expression [568]
GDF5 TT37XV9 Strong Biomarker [569]
GLB1 TTNGJPH Strong Altered Expression [570]
GLP1R TTVIMDE Strong Biomarker [412]
GPBAR1 TTSDVTR Strong Biomarker [571]
GPI TT19JIZ Strong Biomarker [572]
GPR3 TTHZVSK Strong Altered Expression [573]
GRB2 TTEYRJ9 Strong Altered Expression [574]
GUSB TTHS7CM Strong Biomarker [575]
GZMB TTKEPHX Strong Biomarker [576]
HAMP TTRV5YJ Strong Altered Expression [577]
HDAC1 TT6R7JZ Strong Altered Expression [578]
HDAC3 TT4YWTO Strong Altered Expression [579]
HLA-A TTHONFT Strong Biomarker [580]
HLA-B TTGS10J Strong Biomarker [581]
HLA-DQB2 TTL7VOU Strong Genetic Variation [446]
HMGB1 TTWQYB7 Strong Biomarker [582]
HNRNPA2B1 TT8UPW6 Strong ModifyingMutation [583]
HPGDS TTCYE56 Strong Genetic Variation [584]
HPSE TTR7GJO Strong Altered Expression [585]
HRH4 TTXJ178 Strong Biomarker [586]
HSD11B2 TT9H85R Strong Biomarker [587]
HSPB8 TTY0OJN Strong Genetic Variation [588]
HSPD1 TT9HL5R Strong Biomarker [589]
HTR2A TTJQOD7 Strong Genetic Variation [590]
HTRA1 TT8POQR Strong Biomarker [591]
ICA1 TTMX06B Strong Biomarker [592]
ICOS TTE5VP6 Strong Biomarker [593]
IDO1 TTZJYKH Strong Biomarker [594]
IFNB1 TT4TZ8J Strong Biomarker [595]
IGFBP5 TTDWEA8 Strong Biomarker [596]
IGFBP6 TTLAYV8 Strong Biomarker [597]
IKBKB TTJ3E9X Strong Biomarker [598]
IL10RB TTJTRMK Strong Altered Expression [599]
IL12A TTRTK6Y Strong Biomarker [600]
IL12RB2 TT4SWR8 Strong Genetic Variation [601]
IL13 TT0GVCH Strong Biomarker [602]
IL15 TTJFA35 Strong Biomarker [603]
IL15RA TTGN89I Strong Altered Expression [604]
IL16 TTW4R0B Strong Altered Expression [605]
IL17D TTC5LTG Strong Biomarker [606]
IL18RAP TTZUJVE Strong Altered Expression [462]
IL19 TT87RWS Strong Biomarker [607]
IL1A TTPM6HI Strong Altered Expression [608]
IL1R1 TTWOTEA Strong Altered Expression [609]
IL21R TTZO9B0 Strong Biomarker [610]
IL23A TTC1GLB Strong Biomarker [611]
IL32 TTD4G7L Strong Biomarker [612]
IL33 TT5MD4P Strong Biomarker [613]
IL37 TTQTX98 Strong Biomarker [614]
IL4R TTDWHC3 Strong Genetic Variation [615]
IL7 TT8FRMO Strong Biomarker [616]
IL7R TTAWI51 Strong Biomarker [617]
IL9 TT0JTFD Strong Biomarker [602]
INPP5D TTTP2Z1 Strong Altered Expression [618]
IRAK3 TTBPJOK Strong Genetic Variation [619]
IRAK4 TTILUKB Strong Biomarker [620]
IRF1 TT4TU3L Strong Altered Expression [371]
IRS1 TTAJSQ0 Strong Biomarker [621]
ISG15 TTVOH3T Strong Biomarker [622]
ITCH TT5SEWD Strong Biomarker [623]
ITGA1 TTPERWV Strong Biomarker [624]
ITGA4 TTJMF9P Strong Genetic Variation [625]
ITGA6 TT165T3 Strong Biomarker [529]
ITGAE TTH0Z37 Strong Biomarker [624]
ITGAL TT48WR6 Strong Altered Expression [500]
ITGAV TTT1R2L Strong Biomarker [626]
ITGB1 TTBVIQC Strong Biomarker [624]
ITGB2 TTIJWR7 Strong Biomarker [627]
ITPR3 TTH1769 Strong Genetic Variation [446]
JAK1 TT6DM01 Strong Biomarker [628]
JAK2 TTRMX3V Strong Biomarker [629]
JUN TTS7IR5 Strong Posttranslational Modification [630]
KDR TTUTJGQ Strong Biomarker [555]
KHDRBS1 TTAT6C7 Strong Altered Expression [631]
KIF26B TTQWICZ Strong Genetic Variation [632]
KIF5A TTCJPAH Strong Genetic Variation [633]
KIR2DL1 TT4UXPE Strong Biomarker [634]
KIR2DL2 TTU0P73 Strong Biomarker [635]
KIR2DL3 TTEX3SI Strong Biomarker [634]
KIR2DS1 TTVWAGF Strong Genetic Variation [636]
KIR2DS2 TTV3CFI Strong Biomarker [637]
KLK1 TT5T3P6 Strong Altered Expression [638]
KLK3 TTS78AZ Strong Biomarker [639]
KLRC1 TTC4IMS Strong Genetic Variation [640]
KLRK1 TTLRN4A Strong Genetic Variation [641]
LAIR1 TTSI7A8 Strong Biomarker [642]
LANCL1 TTZW8NS Strong Altered Expression [643]
LBP TTVQJLY Strong Genetic Variation [644]
LCN2 TTKTLAI Strong Biomarker [645]
LDLR TTH0DUS Strong Biomarker [646]
LGALS1 TTO3NYT Strong Biomarker [647]
LIF TTGZ5WN Strong Biomarker [648]
LILRB1 TTC0QRJ Strong Biomarker [649]
LNPEP TTY2KP7 Strong Altered Expression [650]
LOX TTQHNAM Strong Biomarker [651]
LPA TTU9LGY Strong Biomarker [652]
LPAR1 TTQ6S1K Strong Altered Expression [653]
LPAR2 TTB7Y8I Strong Altered Expression [654]
LRP5 TT7VMG4 Strong Genetic Variation [655]
LTB TTHQ6US Strong Biomarker [656]
LTB4R TTN53ZF Strong Biomarker [657]
LTB4R2 TTVJX54 Strong Biomarker [658]
LTBR TTFO0PM Strong Biomarker [659]
LY96 TT8S9AV Strong Biomarker [529]
MALT1 TTCI81G Strong Biomarker [660]
MANF TT56RYE Strong Biomarker [661]
MAP2K7 TT6QY3J Strong Biomarker [662]
MAP3K11 TTETX6Q Strong Altered Expression [663]
MAP3K2 TTIX0ZU Strong Biomarker [663]
MAP3K3 TTJZNIG Strong Altered Expression [663]
MAP3K4 TT1RSX7 Strong Genetic Variation [534]
MAP3K5 TTOQCD8 Strong Biomarker [664]
MAP3K7 TTJQT60 Strong Biomarker [665]
MAP4K3 TTI0AHJ Strong Altered Expression [567]
MAPK14 TTQBR95 Strong Biomarker [448]
MAPK8 TT0K6EO Strong Biomarker [662]
MARK2 TTAJ45Y Strong Biomarker [666]
MCL1 TTL53M6 Strong Biomarker [474]
MDK TTV8UE7 Strong Altered Expression [667]
MECP2 TTTAU9R Strong Genetic Variation [668]
MMP12 TTXZ0KQ Strong Biomarker [301]
MMP13 TTHY57M Strong Altered Expression [669]
MOBP TTYUK4F Strong Biomarker [670]
MOG TTQAFX5 Strong Genetic Variation [671]
MPO TTVCZPI Strong Biomarker [672]
MSI1 TTSM4BA Strong Genetic Variation [673]
MSTN TTM8I2X Strong Biomarker [674]
MTF1 TTTQDEO Strong Genetic Variation [324]
MTR TTUTO39 Strong Genetic Variation [675]
MUTYH TTNB0ZK Strong Genetic Variation [676]
MYD88 TTB6Q2O Strong Biomarker [481]
NAMPT TTD1WIG Strong Biomarker [677]
NCAM1 TTVXPHT Strong Biomarker [678]
NFKBIA TTSHAEB Strong Biomarker [485]
NME1 TTDY8JH Strong Genetic Variation [679]
NOD1 TTYSRXM Strong Genetic Variation [680]
NOTCH3 TTVX7IA Strong Altered Expression [681]
NOTCH4 TTXDIK2 Strong Genetic Variation [682]
NPSR1 TTV1C0Z Strong Genetic Variation [683]
NR1I2 TT7LCTF Strong Altered Expression [684]
NR4A2 TT9HKN3 Strong Altered Expression [685]
NR4A3 TTJQB49 Strong Biomarker [301]
NRP1 TTIPJCB Strong Biomarker [310]
OLR1 TTKSND3 Strong Altered Expression [686]
ORAI1 TTE76YK Strong Biomarker [687]
OSCAR TT71Q5Y Strong Altered Expression [688]
OSM TTIVXSE Strong Altered Expression [689]
OSMR TTAH0KM Strong Genetic Variation [690]
P2RX1 TTJW7B3 Strong Biomarker [691]
P2RX3 TT2THBD Strong Biomarker [691]
P2RX4 TT1NLOA Strong Biomarker [691]
P2RY1 TTA93TL Strong Biomarker [691]
P2RY2 TTOZHQC Strong Biomarker [691]
PAX5 TTA4REJ Strong Biomarker [692]
PCSK6 TT75LN9 Strong Biomarker [693]
PCSK9 TTNIZ2B Strong Biomarker [694]
PDE4A TTZ97H5 Strong Biomarker [695]
PF4 TTSG7Q5 Strong Altered Expression [696]
PFKFB3 TTTHMQJ Strong Altered Expression [697]
PGF TT48I1Y Strong Biomarker [698]
PIK3CB TT9H4P3 Strong Biomarker [699]
PLA2G1B TT9V5JH Strong Biomarker [700]
PLA2G4A TTT1JVS Strong Altered Expression [701]
PLG TTP86E2 Strong Biomarker [702]
PPIA TTL2ADK Strong Biomarker [703]
PRG4 TTSKF4V Strong Biomarker [704]
PRKCA TTFJ8Q1 Strong Biomarker [705]
PRKCB TTYPXQF Strong Altered Expression [706]
PRKCZ TTBSN0L Strong Biomarker [707]
PRL TTJ2TSA Strong Altered Expression [708]
PROC TTZUXYS Strong Biomarker [709]
PSIP1 TTH9LDP Strong Biomarker [710]
PTGES TTYLQ8V Strong Biomarker [711]
PTH TT6F7GZ Strong Altered Expression [712]
PTK2 TTON5IT Strong Biomarker [467]
PTN TTA9EJK Strong Altered Expression [713]
PTPN11 TT7WUAV Strong Genetic Variation [601]
RAC1 TT2M9CG Strong Biomarker [355]
RARA TTW38KT Strong Biomarker [714]
RECK TTRZBW7 Strong Altered Expression [715]
RHO TTH0KSX Strong Biomarker [716]
RORA TT1TYN7 Strong Altered Expression [717]
RPS6KA3 TTUM2ZR Strong Altered Expression [718]
RPSA TTLUW5B Strong Biomarker [719]
RUNX2 TTD6SZ8 Strong Biomarker [255]
S100A12 TTQ4ESF Strong Biomarker [696]
S100A4 TTPR5SX Strong Altered Expression [720]
S100B TTQ0V86 Strong Biomarker [721]
S1PR1 TT9JZCK Strong Biomarker [722]
SDC1 TTYDSVG Strong Biomarker [723]
SDC2 TT5H2F0 Strong Altered Expression [724]
SELL TT2IYXF Strong Altered Expression [725]
SEMA3A TTVKD3S Strong Biomarker [726]
SENP1 TTW9HY5 Strong Biomarker [727]
SERPINC1 TT4QPUL Strong Biomarker [728]
SERPINF1 TTR59S1 Strong Genetic Variation [729]
SERPINH1 TTPSWQG Strong Biomarker [730]
SIK1 TT1H6LC Strong Biomarker [731]
SIRT6 TTUXYWF Strong Altered Expression [732]
SLC16A3 TTG6VD5 Strong Biomarker [733]
SLC17A5 TTFSUIA Strong Biomarker [734]
SLC19A1 TT09I7D Strong Genetic Variation [735]
SLC22A1 TTM5Q4V Strong Biomarker [736]
SLC22A2 TT0XOJN Strong Biomarker [737]
SLC38A1 TT1YE9Z Strong Altered Expression [738]
SLC44A4 TT0NYDG Strong Genetic Variation [446]
SLC5A7 TTRV7W3 Strong Biomarker [739]
SLC6A11 TT8RXO5 Strong Genetic Variation [534]
SLC6A2 TTAWNKZ Strong Biomarker [544]
SLC7A5 TTPH2JB Strong Altered Expression [740]
SOCS1 TT8COJM Strong Altered Expression [741]
SOX5 TTXHSZK Strong Biomarker [742]
SP1 TTZEP6S Strong Biomarker [409]
SQSTM1 TTOT2RY Strong Genetic Variation [743]
SSRP1 TTETDKQ Strong Biomarker [744]
SSTR4 TTAE1BR Strong Biomarker [468]
STAT6 TTWOE1T Strong Genetic Variation [745]
SYVN1 TT8XKYM Strong Biomarker [746]
TACR1 TTZPO1L Strong Altered Expression [747]
TACR2 TTYO0A3 Strong Biomarker [748]
TACR3 TTBPGLU Strong Altered Expression [748]
TAGLN TTDRZ9H Strong Altered Expression [749]
TAP1 TT7JZI8 Strong Biomarker [750]
TEC TT1ZV49 Strong Genetic Variation [751]
TEK TT9VGXW Strong Altered Expression [752]
TIE1 TTT4236 Strong Biomarker [753]
TIRAP TTKU0LS Strong Biomarker [754]
TLR1 TTW14D0 Strong Genetic Variation [755]
TLR3 TTD24Y0 Strong Biomarker [756]
TLR5 TTCXP8J Strong Altered Expression [757]
TLR7 TTRJ1K4 Strong Genetic Variation [758]
TLR8 TT8CWFK Strong Genetic Variation [758]
TNC TTUCPMY Strong Biomarker [759]
TNFAIP3 TT5W0IO Strong Biomarker [760]
TNFRSF10B TTW20TU Strong Biomarker [761]
TNFRSF12A TTKPS7V Strong Biomarker [762]
TNFRSF13C TT7NJSE Strong Genetic Variation [763]
TNFRSF17 TTZ3P4W Strong Altered Expression [764]
TNFRSF25 TTDV6BQ Strong Genetic Variation [765]
TNFRSF8 TT2GM5R Strong Altered Expression [766]
TNFRSF9 TTPW9LJ Strong Altered Expression [261]
TNFSF11 TT9E8HR Strong Biomarker [767]
TNFSF12 TTBTDM1 Strong Biomarker [768]
TNFSF13 TTOI1RM Strong Biomarker [769]
TNFSF13B TTWMIDN Strong Biomarker [291]
TNFSF14 TTKVENM Strong Altered Expression [470]
TNFSF15 TTEST6I Strong Genetic Variation [770]
TNFSF4 TTBW580 Strong Genetic Variation [771]
TPP1 TTOVYPT Strong Altered Expression [772]
TPSAB1 TTM1TDX Strong Altered Expression [773]
TSLP TTHMW3T Strong Biomarker [774]
TSPO TTPTXIN Strong Biomarker [775]
TXN TTZJ5U9 Strong Biomarker [776]
TYMP TTO0IB8 Strong Biomarker [307]
TYRP1 TTFRV98 Strong Biomarker [777]
VEGFC TT0QUFV Strong Biomarker [778]
VTCN1 TTCK85E Strong Biomarker [779]
VWF TT3SZBT Strong Biomarker [780]
WNK1 TTJ9UMX Strong Biomarker [781]
WNT5A TTKG7F8 Strong Biomarker [782]
ZAP70 TTUMHT8 Strong Altered Expression [783]
ABHD6 TTSINOV Definitive Genetic Variation [784]
ADCYAP1R1 TT5OREU Definitive Biomarker [785]
ADORA3 TTJFY5U Definitive Genetic Variation [382]
AHSG TTKF4WV Definitive Altered Expression [786]
AZGP1 TTUPYLV Definitive Biomarker [787]
BMP10 TTTG6H1 Definitive Altered Expression [788]
BRD1 TTT09OB Definitive Biomarker [789]
CCR6 TTFDB30 Definitive Genetic Variation [324]
CD28 TTQ13FT Definitive Biomarker [790]
CDK7 TTQYF7G Definitive Biomarker [791]
CHN2 TT39YVO Definitive Posttranslational Modification [792]
CHRNA7 TTLA931 Definitive Altered Expression [793]
COL1A2 TTUABC1 Definitive Biomarker [794]
CPA1 TT3LJ6G Definitive Biomarker [795]
CPB2 TTP18AY Definitive Altered Expression [796]
DOT1L TTSZ8T1 Definitive Altered Expression [797]
F2 TT6L509 Definitive Biomarker [798]
F2RL1 TTQR74A Definitive Biomarker [799]
FABP5 TTNT2S6 Definitive Biomarker [800]
GDF2 TTAP4T1 Definitive Altered Expression [801]
GPER1 TTDSB34 Definitive Biomarker [802]
GPR39 TTTPCNU Definitive Biomarker [803]
GRIA1 TTVPQTF Definitive Biomarker [804]
GRPR TTC1MVT Definitive Biomarker [805]
HCRTR1 TT60Q8D Definitive Altered Expression [806]
IAPP TTHN8EM Definitive Biomarker [807]
IDO2 TTALN9W Definitive Biomarker [808]
IKZF2 TTKT5NV Definitive Altered Expression [809]
IL11RA TTZPLJS Definitive Biomarker [293]
IL2RA TT10Y9E Definitive Biomarker [810]
ITGA5 TTHIZP9 Definitive Biomarker [626]
KYNU TTWQM3J Definitive Biomarker [811]
LIFR TTID542 Definitive Biomarker [812]
LONP1 TTM1VPZ Definitive Biomarker [813]
MAPK10 TT056SO Definitive Biomarker [814]
MBP TT2RY5P Definitive Genetic Variation [815]
MERTK TTO7LKR Definitive Biomarker [802]
NDUFA13 TTRU1NG Definitive Altered Expression [816]
NT5E TTK0O6Y Definitive Biomarker [817]
P2RY11 TTYXPCO Definitive Biomarker [818]
P2RY12 TTZ1DT0 Definitive Biomarker [819]
PARP2 TTQ4V96 Definitive Biomarker [820]
PDK1 TTCZOF2 Definitive Altered Expression [718]
PDPK1 TTYMGWX Definitive Altered Expression [718]
PKD2L1 TTAHD89 Definitive Biomarker [399]
PLTP TTZF6SN Definitive Altered Expression [821]
PML TTLH9NY Definitive Biomarker [822]
PPM1D TTENJAB Definitive Biomarker [823]
PRMT1 TTVOJAI Definitive Altered Expression [417]
PRMT5 TTR1D7X Definitive Biomarker [824]
RARB TTISP28 Definitive Genetic Variation [632]
ROBO1 TTND1YP Definitive Biomarker [825]
RRM2 TT1S4LJ Definitive Altered Expression [826]
SGCG TTSMT9W Definitive Biomarker [827]
SLC3A2 TT5CZSM Definitive Altered Expression [828]
SLC46A1 TTY8Z2E Definitive Altered Expression [417]
SMAD1 TT9GR53 Definitive Biomarker [829]
TNNI3 TTNLDK6 Definitive Biomarker [830]
TRAF6 TTCDR6M Definitive Genetic Variation [831]
TRPM2 TTEBMN7 Definitive Biomarker [832]
TYRO3 TTIEMFN Definitive Biomarker [833]
UTS2R TTW5UDX Definitive Genetic Variation [834]
VDAC1 TTAMKGB Definitive Biomarker [835]
------------------------------------------------------------------------------------
⏷ Show the Full List of 691 DTT(s)
This Disease Is Related to 12 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC8A3 DTYFRQT Disputed Genetic Variation [836]
SLC2A3 DT9SQ3L moderate Genetic Variation [837]
ABCC11 DTWN7FC Strong Biomarker [435]
ABCC5 DTYVM24 Strong Biomarker [243]
ABCC6 DT582KR Strong Genetic Variation [838]
SLC17A2 DTRF4L3 Strong Genetic Variation [839]
SLC17A4 DTHE530 Strong Biomarker [646]
SLC22A5 DT3HUVD Strong Genetic Variation [840]
SLC25A12 DT85HYR Strong Biomarker [467]
SLC52A1 DT7NOKR Strong Altered Expression [841]
SLC7A9 DTP7AEQ Strong Biomarker [842]
SLC14A2 DT8QC7K Definitive Genetic Variation [834]
------------------------------------------------------------------------------------
⏷ Show the Full List of 12 DTP(s)
This Disease Is Related to 45 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
B4GALT7 DEKRS6L Limited Biomarker [843]
CYB5A DE9A2LB Limited Genetic Variation [844]
CYP2R1 DEBIHM3 Limited Genetic Variation [845]
CYP7B1 DE36TMY Limited Altered Expression [846]
FADS1 DE05S8C Limited Genetic Variation [324]
GCLC DESYL1F Limited Altered Expression [358]
GGCT DEKW6PB Limited Genetic Variation [847]
HAGH DE05IKP Limited Genetic Variation [848]
HK1 DEDMAGE Limited Altered Expression [638]
HPRT1 DEVXTP5 Limited Biomarker [849]
NADSYN1 DELF8BA Limited Genetic Variation [845]
NDUFS3 DE741FI Limited Genetic Variation [850]
PCYT1A DEQYXD4 Limited Genetic Variation [851]
UGT1A10 DEL5N6Y Limited Genetic Variation [852]
UGT1A4 DELOY3P Limited Genetic Variation [852]
UGT1A6 DESD26P Limited Genetic Variation [852]
UGT1A7 DEZO4N3 Limited Genetic Variation [852]
UGT1A8 DE2GB8N Limited Genetic Variation [852]
FPGS DECWT2V moderate Genetic Variation [400]
NAT10 DEZV4AP moderate Altered Expression [384]
WARS1 DEPVE0M moderate Altered Expression [853]
WARS2 DEPTKBQ moderate Altered Expression [853]
ABO DESIA7R Strong Biomarker [854]
ACP5 DESITDW Strong Biomarker [855]
CPA4 DEXKD7J Strong Genetic Variation [673]
DHCR7 DEL7GFA Strong Genetic Variation [856]
GLS DE3E0VT Strong Altered Expression [857]
GPT DER5HFI Strong Biomarker [858]
MSRA DEU2ZBY Strong Genetic Variation [859]
NAT2 DER7TA0 Strong Genetic Variation [860]
PGM1 DEA3VM1 Strong Biomarker [861]
PON2 DEHJU7E Strong Biomarker [862]
SAT1 DEMWO83 Strong Biomarker [863]
SCLY DEH4TD6 Strong Genetic Variation [864]
SPR DEJVDAT Strong Biomarker [865]
SULT2A1 DE0P6LK Strong Biomarker [866]
THOP1 DE95LJC Strong Genetic Variation [784]
TPMT DEFQ8VO Strong Genetic Variation [867]
UBASH3B DE10BJ5 Strong Genetic Variation [868]
VARS1 DEUPF5K Strong Genetic Variation [446]
AKR1D1 DEVON3M Definitive Biomarker [869]
ALDH1A2 DEKN1H4 Definitive Altered Expression [870]
CYP26B1 DEZT8FM Definitive Altered Expression [871]
NMNAT3 DERBKPU Definitive Altered Expression [872]
SMOX DEOH5V3 Definitive Biomarker [873]
------------------------------------------------------------------------------------
⏷ Show the Full List of 45 DME(s)
This Disease Is Related to 992 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
A2M OTFTX90K Limited Altered Expression [874]
AAAS OTJT9T23 Limited Biomarker [875]
ADAD1 OTXRDF3Z Limited Genetic Variation [876]
ADAMTS3 OT2U6VF5 Limited Biomarker [442]
ADAMTS7 OTVKZ1DV Limited Biomarker [877]
ADGRE2 OTUYJVYG Limited Biomarker [878]
ADGRE5 OTTSB84Q Limited Biomarker [878]
AFF3 OTR0705Z Limited Genetic Variation [563]
AIRE OTA7G1Y1 Limited Altered Expression [879]
AKIRIN2 OTQ6WSKW Limited Biomarker [880]
ALDH1A3 OT1C9NKQ Limited Biomarker [881]
ANKRD55 OT62KZII Limited Genetic Variation [324]
ANXA3 OTDD8OI7 Limited Genetic Variation [416]
ARC OTN2QQPG Limited Genetic Variation [882]
ARHGEF7 OT9BPJCL Limited Altered Expression [883]
ATN1 OTNZFLKY Limited Genetic Variation [884]
ATOH1 OTBZYG2R Limited Altered Expression [885]
ATP6V1G1 OTBT1O58 Limited Biomarker [886]
ATP6V1G2 OTM1DSKL Limited Genetic Variation [446]
B3GNTL1 OTYWGHF1 Limited Genetic Variation [887]
BAIAP2L1 OTZ71SK9 Limited Biomarker [888]
BCL3 OT1M5B95 Limited Altered Expression [889]
BMP5 OTC0Y6E0 Limited Altered Expression [890]
BTN1A1 OTSQWC36 Limited Biomarker [891]
BTNL2 OTTTEMZA Limited Genetic Variation [682]
C2 OTHMF4YM Limited Genetic Variation [446]
CABIN1 OT4G5CIK Limited Biomarker [892]
CALD1 OTNJKJ6Q Limited Biomarker [893]
CALHM6 OTLX9B4Y Limited Biomarker [280]
CARD9 OTJ81AWD Limited Biomarker [894]
CASP12 OTY2W6FG Limited Biomarker [895]
CAVIN2 OTFHHDRU Limited Biomarker [896]
CBLL2 OTB4AD3V Limited Biomarker [746]
CCRL2 OT5PX0RX Limited Altered Expression [897]
CCT3 OTL6EOS1 Limited Genetic Variation [898]
CD247 OT45FGUX Limited Altered Expression [899]
CD63 OT2UGZA9 Limited Biomarker [900]
CD84 OTAY5B0F Limited Genetic Variation [901]
CD93 OT6HZT6H Limited Altered Expression [902]
CDKN3 OTBE3H07 Limited Genetic Variation [266]
CDSN OTQW4HV6 Limited Altered Expression [903]
CENPJ OTZCQZN5 Limited Altered Expression [904]
CHID1 OT4DIUKC Limited Altered Expression [905]
CHP1 OTHTXN1A Limited Altered Expression [265]
CIC OTFXCHNZ Limited Biomarker [906]
CLEC10A OTD8HQT6 Limited Altered Expression [907]
CLEC1B OTO38TRG Limited Biomarker [908]
CLTA OTLHOXMQ Limited Genetic Variation [909]
COG2 OTKQH4N4 Limited Biomarker [910]
COL11A2 OT3BQUBH Limited Genetic Variation [891]
COL12A1 OTHLTV53 Limited Altered Expression [911]
COX5A OTP0961M Limited Biomarker [912]
CPQ OTTNZNLD Limited Altered Expression [913]
CRABP1 OTISDG5X Limited Biomarker [914]
CREB3 OT9617UO Limited Biomarker [915]
CREBRF OT2GK1HI Limited Altered Expression [880]
CREG1 OTRHJ8HK Limited Biomarker [916]
CRKL OTOYSD1R Limited Biomarker [917]
CXCL6 OTFTCQ4O Limited Biomarker [893]
CYCS OTBFALJD Limited Biomarker [918]
CYLD OT37FKH0 Limited Biomarker [919]
DAXX OTX6O7PL Limited Genetic Variation [446]
DBR1 OTLTWLTE Limited Genetic Variation [920]
DCLRE1C OTW3KB1I Limited Biomarker [921]
DEFA1 OT5N1B9B Limited Biomarker [257]
DEFA3 OTO3N8E1 Limited Biomarker [257]
DHX32 OTDYB66V Limited Altered Expression [335]
DLEU7 OTVKX1YP Limited Biomarker [922]
DNAH8 OTGES2OU Limited Biomarker [875]
DNAJA2 OTKF1VBT Limited Biomarker [923]
DNAJB4 OTUD01BK Limited Altered Expression [924]
DNAJB6 OTMHIIAN Limited Biomarker [923]
DNAJC14 OT7DPIVN Limited Biomarker [923]
DST OTHZBM4X Limited Genetic Variation [925]
EBAG9 OTTQLQCP Limited Biomarker [926]
EFNB1 OT7JJW8P Limited Altered Expression [927]
EGR2 OTAVQ78J Limited Biomarker [928]
EIF4G1 OT2CF1E6 Limited Biomarker [929]
EMCN OTS03CZC Limited Genetic Variation [561]
ENGASE OTKXNR5B Limited Biomarker [930]
ETFA OTXX61VZ Limited Biomarker [931]
EXOC4 OT5EWXAN Limited Biomarker [932]
EXOSC1 OTB1QQJJ Limited Genetic Variation [933]
FAM167A OT9JF3JQ Limited Genetic Variation [934]
FBXO2 OTF3677S Limited Biomarker [935]
FCRL4 OT3DVTRV Limited Biomarker [936]
FOXJ3 OTXAUJ47 Limited Biomarker [937]
GAB2 OTBFN705 Limited Altered Expression [938]
GDPD5 OTUM65JL Limited Altered Expression [939]
GIN1 OT6L79OO Limited Biomarker [263]
GLCCI1 OTU0R1CU Limited Altered Expression [940]
GNA12 OT3IRZH3 Limited Biomarker [941]
GNB3 OTA6HYBA Limited Genetic Variation [942]
GPC1 OTQKRSSV Limited Altered Expression [943]
GPLD1 OTUUQOVY Limited Biomarker [320]
GPSM3 OT2MO458 Limited Genetic Variation [944]
GRHL3 OT1V4ZEH Limited Biomarker [945]
GRK1 OT7MPSG7 Limited Biomarker [287]
GRP OT8JDFNI Limited Biomarker [946]
GSDMB OTWA7P10 Limited Genetic Variation [947]
HAPLN1 OTXWR9TJ Limited Biomarker [888]
HAS3 OTPM8IL8 Limited Altered Expression [948]
HESX1 OT5E2Z4G Limited Biomarker [949]
HIP1 OT7AKCFQ Limited Biomarker [950]
HLA-DQB1 OTVVI3UI Limited Posttranslational Modification [951]
HOOK1 OTTTKV7V Limited Altered Expression [638]
HOXD11 OT9XGA4G Limited Biomarker [888]
HOXD4 OTQR4WCG Limited Altered Expression [952]
HSPA1L OTC2V1K6 Limited Genetic Variation [446]
HSPBP1 OTRS37HK Limited Altered Expression [953]
IFI35 OTV9RZ53 Limited Altered Expression [954]
IFI44 OTOKSZVA Limited Altered Expression [954]
IFNLR1 OTWWWK45 Limited Altered Expression [599]
IGFBP4 OT2HZRBD Limited Altered Expression [955]
IL20RA OTSIVBVS Limited Altered Expression [498]
IL27RA OTSQBAKI Limited Altered Expression [956]
IL34 OTZ15VVK Limited Altered Expression [957]
IL36B OTYT4LP5 Limited Altered Expression [958]
IL4I1 OTK54C63 Limited Biomarker [959]
IRF4 OT1DHQ1P Limited Altered Expression [960]
ISYNA1 OT49ONSE Limited Genetic Variation [961]
ITGA2B OT4Y17PY Limited Altered Expression [962]
IVNS1ABP OTYHL4I7 Limited Biomarker [963]
KCNA4 OTTIGYN7 Limited Altered Expression [638]
KCNIP3 OTCQPEM4 Limited Genetic Variation [964]
KIR2DL5A OT09FZE1 Limited Genetic Variation [634]
KIR2DL5B OTSV0JL9 Limited Genetic Variation [634]
KIR2DS3 OT3PSLDL Limited Genetic Variation [965]
KIR2DS4 OT00N6UJ Limited Biomarker [966]
KIR3DS1 OTJWIO4T Limited Genetic Variation [965]
KL OTD4VWU6 Limited Biomarker [967]
KPNA2 OTU7FOE6 Limited Biomarker [968]
KRT16 OTGA0EQN Limited Altered Expression [315]
KRTAP5-9 OTJ9E3R7 Limited Biomarker [969]
LECT2 OTSFZ9JD Limited Genetic Variation [970]
LILRA1 OTZ4NA7Q Limited Biomarker [971]
LILRA2 OT1O2K47 Limited Altered Expression [297]
LRAT OTB7CJKY Limited Altered Expression [972]
LRG1 OTLD0KWA Limited Biomarker [973]
LSP1 OTSPSIFO Limited Altered Expression [974]
LVRN OTHBF42S Limited Altered Expression [975]
MAB21L2 OTZM5VMX Limited Biomarker [888]
MACIR OTPSW8Y8 Limited Genetic Variation [324]
MAGEE1 OTOQQO2X Limited Biomarker [976]
MAL OTBM30SW Limited Biomarker [256]
MAPK13 OT0W9GE7 Limited Altered Expression [977]
MFSD4B OTHHKWRT Limited Genetic Variation [978]
MGARP OTL90XO8 Limited Biomarker [888]
MGAT5 OTU4DD4G Limited Biomarker [979]
MICA OTPEIEAR Limited Genetic Variation [980]
MINDY4 OTBZ2SZB Limited Altered Expression [461]
MMP19 OTLSTT2B Limited Biomarker [981]
MMP20 OT16S5S3 Limited Biomarker [305]
MMP25 OT3BG37V Limited Biomarker [305]
MPIG6B OTVNKQWA Limited Genetic Variation [446]
MRPL17 OTBPCPVW Limited Altered Expression [904]
MSH6 OT46FP09 Limited Biomarker [982]
MUC3A OTI4XUDY Limited Altered Expression [308]
MUL1 OT2JC9YR Limited Biomarker [746]
MYO18B OTGYY4NK Limited Altered Expression [983]
NDUFA4L2 OTK0PG7R Limited Biomarker [301]
NDUFA7 OT8CV3H5 Limited Biomarker [984]
NELFCD OTOLTZPU Limited Biomarker [985]
NFATC2 OTK5T6HZ Limited Altered Expression [986]
NFIL3 OTQH9HM3 Limited Biomarker [987]
NFKBIL1 OTYFTPS0 Limited Genetic Variation [446]
NKAP OT7K7I8Q Limited Genetic Variation [988]
NLRP2 OTJA81JU Limited Genetic Variation [989]
NPC2 OTE9UEJC Limited Biomarker [990]
NR2F1 OTGWZWYL Limited Altered Expression [991]
NRSN1 OT1KKXC8 Limited Altered Expression [265]
NUMB OTMB586Q Limited Biomarker [992]
OAZ1 OTPT0PKZ Limited Altered Expression [993]
ODF1 OTTSURLA Limited Altered Expression [994]
OR2AG1 OTEITRP4 Limited Genetic Variation [995]
ORMDL3 OTAB7MZF Limited Genetic Variation [947]
OSCP1 OTZ4IFGJ Limited Altered Expression [883]
PDIA3 OTHPQ0Q3 Limited Biomarker [996]
PER3 OTVKYVJA Limited Biomarker [997]
PGK1 OT6V1ICH Limited Altered Expression [998]
PIGR OT6GLSUL Limited Biomarker [999]
PIR OT8ALXHU Limited Altered Expression [1000]
PKD1 OT5ALRZ5 Limited Altered Expression [315]
PLA2G10 OTRZ2L5A Limited Biomarker [700]
POLD1 OTWO4UCJ Limited Biomarker [1001]
POU2AF1 OTOO6WHL Limited Biomarker [1002]
POU2F1 OTK7ELJ0 Limited Altered Expression [1003]
POU3F1 OTYARA94 Limited Biomarker [263]
PRAP1 OT48QD82 Limited Biomarker [1004]
PRELP OT9EEBUJ Limited Altered Expression [386]
PRF1 OTFVXD7H Limited Biomarker [1005]
PTMA OT2W4T1M Limited Biomarker [1006]
PTPN22 OTDCNTC3 Limited Unknown [1007]
QPCTL OTJD4K8A Limited Altered Expression [333]
RABGEF1 OTWC3Z3R Limited Altered Expression [1008]
RAG1 OTV131E4 Limited Altered Expression [1009]
RAG2 OTG9UYTW Limited Altered Expression [1009]
RAP1A OT5RH6TI Limited Altered Expression [1008]
REM1 OTUXL0HC Limited Biomarker [1010]
REV3L OT0OP8EJ Limited Genetic Variation [978]
REXO1 OTZT6RAW Limited Altered Expression [1011]
RGMB OT2DROYU Limited Biomarker [888]
RNASE1 OTKZ7CO9 Limited Biomarker [1012]
ROBO3 OTPVG40S Limited Genetic Variation [1013]
RPP14 OT4OYFSK Limited Genetic Variation [324]
RPS4X OTIH80EK Limited Biomarker [1014]
RPS6KA4 OTTK8MUO Limited Biomarker [336]
RRAS OTBBF28C Limited Biomarker [669]
RSPO2 OT3HHXU0 Limited Altered Expression [724]
RTKN2 OTV2AXQM Limited Genetic Variation [1015]
SAAL1 OTRTVFVO Limited Biomarker [1016]
SACM1L OT6ORKTD Limited Genetic Variation [1017]
SAPCD1 OTUJT8F9 Limited Genetic Variation [891]
SELENOS OTUEWIU9 Limited Genetic Variation [1018]
SERPINB2 OT72QLZB Limited Altered Expression [1019]
SFRP5 OTLCVVSH Limited Biomarker [1020]
SH3BP2 OT90JNBS Limited Biomarker [1021]
SH3PXD2A OTYRQJIH Limited Genetic Variation [673]
SIAE OTDQUESH Limited Genetic Variation [1022]
SIGLEC1 OTNWSQA9 Limited Biomarker [954]
SLAMF1 OTBTT3ZQ Limited Biomarker [1023]
SLC7A4 OTAVC6QS Limited Genetic Variation [1024]
SLIT3 OTU8MKEU Limited Altered Expression [1013]
SMG1 OTTS3SXE Limited Altered Expression [315]
SMTNL2 OTOZL9IG Limited Biomarker [1025]
SNAPIN OT2FBS5N Limited Biomarker [1026]
SPA17 OT8J7T7U Limited Altered Expression [1027]
SPAG11A OTNQ9UB0 Limited Biomarker [328]
SPAG16 OTIFUPYD Limited Altered Expression [1028]
SRF OTW18FQN Limited Altered Expression [1029]
SSB OTCCTPBR Limited Biomarker [1030]
STATH OTQHBHM9 Limited Biomarker [1031]
STRA6 OT2IDF27 Limited Altered Expression [1032]
STXBP6 OTUEKTIP Limited Biomarker [1033]
SUPT20H OTTMC0LH Limited Genetic Variation [1034]
SYNGR1 OT0MBUK5 Limited Genetic Variation [324]
TAB2 OTPZK76F Limited Genetic Variation [1035]
TAC4 OTYWPPM3 Limited Altered Expression [638]
TAT OT2CJ91O Limited Biomarker [1036]
TEF OTY3LAD9 Limited Biomarker [987]
TERF2IP OT3M5P3G Limited Altered Expression [1008]
TESPA1 OTEGT4GI Limited Biomarker [1037]
TET1 OTZDHT1D Limited Biomarker [1038]
TFF2 OTRXB19X Limited Altered Expression [347]
TG OT3ELHIJ Limited Biomarker [1039]
THNSL2 OTLXYPYV Limited Biomarker [1040]
TLE3 OTR9PH95 Limited Biomarker [263]
TMED2 OTBLO7RW Limited Altered Expression [265]
TMEM187 OTOE4G8T Limited Genetic Variation [1041]
TNFAIP2 OTRZH80H Limited Biomarker [301]
TNFSF9 OTV9L89D Limited Altered Expression [1042]
TNIP3 OTSAE5UE Limited Biomarker [1043]
TNXB OTVBWAV5 Limited Genetic Variation [446]
TPD52 OTPKSK43 Limited Genetic Variation [324]
TPPP OTCFMSUF Limited Altered Expression [265]
TRAF5 OTSBTLO0 Limited Biomarker [1044]
TRIM21 OTA4UJCF Limited Biomarker [1045]
A1CF OTJBKFA1 Disputed Biomarker [364]
AKAP12 OTCVRDDX Disputed Genetic Variation [1046]
APOL6 OTYTBJEG Disputed Genetic Variation [377]
ASAH1 OT1DNGXL Disputed Genetic Variation [1047]
ASPM OTKXQMNA Disputed Biomarker [364]
CCDC88C OTIU02BS Disputed Genetic Variation [377]
CIZ1 OT3UKHPI Disputed Altered Expression [1048]
COG6 OTDLQITC Disputed Genetic Variation [1049]
CXCL3 OTSL94KH Disputed Biomarker [523]
FGD1 OTV3T64P Disputed Biomarker [1050]
GGT6 OTAQWSCC Disputed Biomarker [1025]
GPR65 OTCF5O4G Disputed Biomarker [1051]
HIVEP3 OTM3QT3L Disputed Biomarker [1052]
HOXD13 OTWSC8TF Disputed Altered Expression [1053]
IFI16 OT4SPU0U Disputed Biomarker [1054]
IFIT2 OTI4EOAR Disputed Altered Expression [398]
IL9R OTILCLXA Disputed Biomarker [1055]
ITGA9 OTHN1IKA Disputed Altered Expression [1056]
KAT7 OTUN98IC Disputed Altered Expression [1057]
KRT5 OTVGI9HT Disputed Biomarker [1058]
LAMA3 OTFME7HT Disputed Biomarker [370]
LMLN OTQF0JPY Disputed Altered Expression [377]
MARCHF1 OTI2EYO6 Disputed Biomarker [1059]
MX1 OT6X8G5T Disputed Biomarker [1060]
NFIA OTDHQ9CG Disputed Biomarker [254]
NFKBIB OTY1ZJXH Disputed Biomarker [332]
NONO OTN36Q6U Disputed Altered Expression [398]
NPPA OTMQNTNX Disputed Biomarker [503]
PCLAF OTMVIOUU Disputed Biomarker [1061]
PCNP OTJUQ122 Disputed Biomarker [1062]
PLEKHO1 OTMVUQ9W Disputed Altered Expression [1063]
PLK3 OT19CT2Z Disputed Biomarker [1064]
PPP1R15A OTYG179K Disputed Altered Expression [1065]
PPP1R1A OTGTAGCV Disputed Altered Expression [365]
PRDX6 OTS8KC8A Disputed Altered Expression [1066]
PTPRU OTHDO0QG Disputed Biomarker [1067]
RAB40B OTCA9ZF5 Disputed Altered Expression [1068]
ROPN1L OTRWZJ68 Disputed Biomarker [364]
SAA4 OTCE1WXO Disputed Biomarker [1069]
SRSF11 OTZSV6CZ Disputed Altered Expression [398]
THEMIS OTXODBXJ Disputed Biomarker [1070]
TMPRSS13 OTMAOAP3 Disputed Altered Expression [377]
TNFAIP8L2 OTII0RM0 Disputed Altered Expression [1062]
AGXT2 OTO6QUTM moderate Biomarker [1071]
ALPP OTZU4G9W moderate Altered Expression [384]
ANKH OTCN25R5 moderate Genetic Variation [1072]
APOBEC3C OTPL0AI1 moderate Biomarker [1073]
ARL15 OT00YSWZ moderate Biomarker [1074]
ATF2 OTNIZPEA moderate Genetic Variation [1075]
ATG5 OT4T5SMS moderate Genetic Variation [324]
ATRNL1 OTY5JUX2 moderate Altered Expression [384]
BCS1L OT5PY5CY moderate Biomarker [1076]
C1QTNF3 OTOJMWW0 moderate Altered Expression [1077]
CAPG OTJ86KI6 moderate Biomarker [1078]
CAV2 OT1FGRQX moderate Biomarker [529]
CBLIF OTNE20WU moderate Altered Expression [1079]
CCL7 OTDIS99H moderate Biomarker [1080]
CCL8 OTCTWYN8 moderate Genetic Variation [424]
CEP70 OTMY5KAE moderate Altered Expression [1081]
CHD7 OTHNIZWZ moderate Altered Expression [1082]
CIAO1 OTCU8PFI moderate Biomarker [1083]
CIRBP OTXWTPBL moderate Biomarker [1084]
CLN8 OT0D4CB5 moderate Genetic Variation [1072]
DNER OT2GH2E5 moderate Biomarker [1085]
FAM107A OTBG61YZ moderate Genetic Variation [416]
GATA1 OTX1R7O1 moderate Biomarker [1086]
GCFC2 OTC7FRXL moderate Altered Expression [1087]
GNS OTNFKYGB moderate Biomarker [1088]
GPRC5A OTPOCWR7 moderate Biomarker [529]
HMMR OT4M0JTZ moderate Altered Expression [1089]
IL17RA OTVVI8ER moderate Biomarker [1090]
INSRR OT3F75WA moderate Biomarker [1091]
ITIH1 OTSXJGQF moderate Altered Expression [1092]
KAT5 OTL7257A moderate Biomarker [1093]
KIDINS220 OTLBH2MA moderate Biomarker [1094]
LILRA3 OTBNQCOS moderate Genetic Variation [1095]
LRIT1 OTNEQPMZ moderate Biomarker [423]
MBD2 OTUQPP0R moderate Biomarker [409]
MFAP4 OT5W64QY moderate Biomarker [1096]
MRE11 OTGU8TZM moderate Biomarker [1097]
NFAT5 OTKIE59S moderate Biomarker [1098]
NFKBIE OTLAYEL9 moderate Altered Expression [1099]
NHS OTKE8QAT moderate Genetic Variation [1100]
NLRC3 OTWLLFFN moderate Biomarker [1101]
OXA1L OTS0BFRD moderate Biomarker [1102]
PDLIM3 OTVXQC81 moderate Altered Expression [384]
PGLYRP1 OTBTPR2T moderate Biomarker [1103]
PRSS2 OTOMVUWL moderate Biomarker [1104]
RAC2 OTAOHFNH moderate Altered Expression [1105]
RASGRP2 OTABVLVQ moderate Altered Expression [1106]
S100A11 OTI57KDN moderate Biomarker [1107]
SMR3A OT6NAJJI moderate Biomarker [1073]
SMS OT8JYKNH moderate Biomarker [1108]
SUMO2 OT1Y5IKN moderate Altered Expression [414]
SUMO3 OTTUJQJ1 moderate Altered Expression [414]
TBCA OTCCWMGK moderate Biomarker [1109]
TGIF1 OTN9VHAG moderate Altered Expression [1110]
THY1 OTVONVTB moderate Biomarker [1111]
ABCF1 OT6Q079J Strong Genetic Variation [327]
ACAN OTUOCW8K Strong Biomarker [1112]
ACOT7 OT7C68YV Strong Biomarker [438]
ACOXL OTW680HT Strong Genetic Variation [751]
ACP1 OTJ9CKLU Strong Genetic Variation [1113]
ACSBG1 OTM040MW Strong Altered Expression [1114]
ACTB OT1MCP2F Strong Biomarker [1115]
ACTBL2 OTD6B81U Strong Biomarker [438]
ACTG2 OTRDWUO0 Strong Biomarker [438]
ACTN1 OTUCLNXH Strong Biomarker [1116]
ADA2 OTGCV24S Strong Genetic Variation [1117]
ADAM11 OTPTVW5W Strong Biomarker [1118]
ADAM15 OTZ7VLTP Strong Altered Expression [1119]
ADAMTS12 OTG7HEA2 Strong Biomarker [1120]
ADAR OTQNOHR8 Strong Altered Expression [1121]
ADI1 OT8IOD03 Strong Biomarker [1122]
ADIPOR1 OT65ZFZN Strong Altered Expression [1123]
ADIPOR2 OT2HDTL8 Strong Altered Expression [1123]
ADRM1 OTOU4EY6 Strong Biomarker [1124]
AGBL3 OTVH64PO Strong Biomarker [1125]
AHI1 OT8K2YWY Strong Altered Expression [977]
AHNAK OT6KH1WG Strong Biomarker [1126]
AHSA1 OTC7AFHT Strong Biomarker [448]
AIFM2 OT57XWXO Strong Genetic Variation [673]
ALPK1 OTBW6SGD Strong Genetic Variation [673]
AMPD1 OTU17BCI Strong Biomarker [1127]
ANO8 OT07SRRX Strong Genetic Variation [751]
ANP32B OT3SQMLU Strong Biomarker [769]
ANXA6 OT9KIQ0Y Strong Genetic Variation [868]
APOM OTI3FQQC Strong Genetic Variation [1128]
ARHGEF2 OTBQTFRT Strong Altered Expression [643]
ARHGEF5 OTUVGFT9 Strong Genetic Variation [1129]
ARID5B OTUQ4CQY Strong Genetic Variation [324]
ARMH1 OTTJC0D6 Strong Altered Expression [643]
ASB15 OTI0ZVLJ Strong Genetic Variation [327]
ASCC1 OTH4VAP9 Strong Biomarker [1130]
ASF1A OT4S44GP Strong Biomarker [699]
ATF6B OTT2ZGSR Strong Genetic Variation [446]
ATF7IP OTU6ZA7F Strong Biomarker [1131]
ATG16L1 OTEOYC5D Strong Biomarker [743]
ATP6V1H OTX17GQ9 Strong Biomarker [1132]
B3GAT1 OTXFP98E Strong Altered Expression [1133]
B3GNT2 OTE69HV8 Strong Genetic Variation [1134]
B3GNT9 OTO385AU Strong Biomarker [529]
BACH2 OT17GS18 Strong Genetic Variation [406]
BAG6 OT4Z0S2U Strong Genetic Variation [446]
BANP OT1JMTBD Strong Biomarker [1135]
BATF OT9VSD2D Strong Biomarker [692]
BCL2L15 OTD943W0 Strong Genetic Variation [327]
BCR OTCN76C1 Strong Biomarker [1136]
BEST1 OTWHE1ZC Strong Biomarker [536]
BGLAP OTK1YLWQ Strong Biomarker [1137]
BHLHE41 OTY9GJ1Y Strong Biomarker [1138]
BTG3 OT9ANHVT Strong Biomarker [1139]
C1QTNF6 OT57EPQC Strong Altered Expression [1140]
C4A OTXMOYXU Strong Biomarker [1141]
C6orf47 OTMKBNDD Strong Genetic Variation [446]
CAMKMT OTLJBRUW Strong Biomarker [359]
CAPRIN1 OTEJAMS3 Strong Biomarker [1142]
CASC3 OTLK3K4U Strong Altered Expression [1143]
CAST OTBXZZGF Strong Biomarker [1144]
CASTOR1 OTYIH7WK Strong Genetic Variation [633]
CCHCR1 OT22C116 Strong Genetic Variation [327]
CCL1 OT23NON8 Strong Biomarker [480]
CCL13 OTNX0JD0 Strong Biomarker [1145]
CCL14 OT8QETQU Strong Biomarker [480]
CCL18 OT7JYSK9 Strong Altered Expression [609]
CCL19 OTQ2UJMH Strong Biomarker [1146]
CCL24 OT9LGHV0 Strong Genetic Variation [1147]
CCL25 OTLWJ8CJ Strong Biomarker [487]
CCL27 OTUZYC61 Strong Altered Expression [384]
CCL28 OTY6XNQ7 Strong Altered Expression [1148]
CCL4 OT6B8P25 Strong Altered Expression [1149]
CCL4L2 OTDBSXOU Strong Altered Expression [1149]
CCN5 OTADU8JJ Strong Altered Expression [1150]
CCN6 OTRFHQ2Z Strong Altered Expression [1150]
CCNG2 OTII38K2 Strong Genetic Variation [534]
CCR10 OT7ZWSSD Strong Altered Expression [1148]
CD1C OT4XINUJ Strong Altered Expression [1151]
CD1D OT3ROU4J Strong Altered Expression [1152]
CD48 OT83ZNPP Strong Genetic Variation [1153]
CD68 OTOYEY3J Strong Biomarker [1154]
CD82 OTH8MC64 Strong Biomarker [1155]
CDAN1 OTCVZRG6 Strong Biomarker [1156]
CDC42 OT5QBC5M Strong Altered Expression [1157]
CDC42EP3 OTUZ3U9Z Strong Genetic Variation [673]
CDCA5 OTZLCQ5U Strong Biomarker [504]
CDCP1 OTD7RRWK Strong Altered Expression [1158]
CDK2AP2 OTR99SJ8 Strong Altered Expression [1159]
CDK5RAP2 OTRKEVTY Strong Genetic Variation [1160]
CDKN2D OT2TTZPZ Strong Altered Expression [549]
CEBPD OTNBIPMY Strong Biomarker [1161]
CEMIP OTK80FYN Strong Altered Expression [911]
CEP89 OT1VEFSL Strong Genetic Variation [1162]
CFDP1 OTXY7J96 Strong Altered Expression [678]
CHST4 OTESMIW5 Strong Biomarker [1163]
CIAO3 OT0V91PK Strong Biomarker [1164]
CILP OTKEY2NJ Strong Biomarker [1165]
CIP2A OTVS2GXA Strong Biomarker [1166]
CISH OT8T5NYL Strong Biomarker [1167]
CLEC5A OT19WV30 Strong Altered Expression [1168]
CLEC7A OTRTBH27 Strong Altered Expression [1169]
CLOCK OTNEOJY7 Strong Biomarker [1170]
CLSTN2 OT2PJYHX Strong Genetic Variation [327]
CLYBL OTXZLTST Strong Genetic Variation [1171]
COLQ OT4BHUGQ Strong Biomarker [1172]
COMP OTS2FPMI Strong Biomarker [704]
COTL1 OT6YCNLF Strong Genetic Variation [1173]
COX1 OTG3O9BN Strong Altered Expression [1174]
COX2 OTTMVBJJ Strong Altered Expression [401]
CP OTM8JE4Y Strong Altered Expression [1175]
CRABP2 OTY01V9G Strong Altered Expression [800]
CRISP2 OT8HLTV5 Strong Biomarker [1176]
CRISP3 OTBSWMPL Strong Genetic Variation [307]
CSMD3 OTAT75SW Strong Genetic Variation [561]
CSNK2B OT2WW7R1 Strong Genetic Variation [446]
CSTF3 OT1Y7B5U Strong Genetic Variation [534]
CTHRC1 OTV88X2G Strong Altered Expression [1177]
CTIF OT7DU7WN Strong Genetic Variation [327]
CUL1 OTXPE1UZ Strong Genetic Variation [1178]
CUL5 OTMTZD47 Strong Genetic Variation [324]
CXCL16 OTD49T9R Strong Altered Expression [528]
CXCL5 OTZOUPCA Strong Altered Expression [1179]
CYRIB OTLRN4L1 Strong Genetic Variation [673]
DBP OTE0W7LN Strong Genetic Variation [1180]
DCDC2C OTK5F95W Strong Genetic Variation [534]
DCTN4 OTM7C943 Strong Altered Expression [631]
DDA1 OTAZIAIH Strong Genetic Variation [751]
DDX39A OT0Z6E1K Strong Biomarker [842]
DDX39B OTEVCFVU Strong Genetic Variation [446]
DDX6 OTKWXVDY Strong Altered Expression [398]
DECR1 OTCDIR6X Strong Biomarker [1181]
DEDD OTIL349E Strong Biomarker [1182]
DENND1A OTONDAA0 Strong Genetic Variation [673]
DGKQ OT8OEPYT Strong Genetic Variation [601]
DHX16 OTW8KZAU Strong Genetic Variation [327]
DHX40 OTOL02QN Strong Altered Expression [1183]
DLG2 OTQ3BD8U Strong Genetic Variation [561]
DNASE1L3 OTEUIMC2 Strong Genetic Variation [601]
DNASE2 OT6RC1BL Strong Altered Expression [1184]
DOCK2 OTZTS3PA Strong Biomarker [1185]
DR1 OTR081M4 Strong Biomarker [1186]
EBF3 OTB0IWLW Strong Posttranslational Modification [1187]
EBNA1BP2 OTBRVMZH Strong Altered Expression [643]
EFEMP2 OT0I2B4J Strong Altered Expression [1188]
EFHC2 OTI459M8 Strong Biomarker [1189]
EGFL8 OTECTJ7K Strong Genetic Variation [446]
ELAVL2 OT6EJ8MQ Strong Biomarker [253]
ELF3 OTUTLEQO Strong Altered Expression [1190]
ELMO1 OTY2ORXK Strong Genetic Variation [563]
ENHO OT91QASK Strong Altered Expression [1191]
ENOX1 OT4WOLA8 Strong Genetic Variation [534]
ERG OTOTX9VU Strong Biomarker [1192]
ERICH1 OTYGUU10 Strong Genetic Variation [1193]
EXT1 OTRPALJK Strong Biomarker [1194]
FADD OTV7GFHH Strong Altered Expression [1195]
FAM53B OTVD7OU6 Strong Biomarker [1196]
FBL OTRODIE5 Strong Genetic Variation [1197]
FCGR2C OTNLMNYB Strong Biomarker [1198]
FCRLA OT6MK4M1 Strong Genetic Variation [377]
FGB OT6RKLI9 Strong Biomarker [1199]
FGF13 OTHNNVSG Strong Altered Expression [1200]
FHL2 OT0OAYWT Strong Altered Expression [1201]
FHL5 OT6C00Z1 Strong Biomarker [438]
FIP1L1 OTF91GTL Strong Biomarker [1202]
FLACC1 OTZN9TZV Strong Genetic Variation [324]
FLG OTE9QDV6 Strong Biomarker [1125]
FLNB OTPCOYL6 Strong Biomarker [1203]
FLT3LG OTU0YGC4 Strong Biomarker [1204]
FOSB OTW6C05J Strong Biomarker [530]
FOXJ1 OT7LLBZ7 Strong Genetic Variation [1205]
FOXO4 OT90X9LN Strong Altered Expression [1206]
FTL OTYQA8A6 Strong Altered Expression [1207]
G0S2 OT8FL49L Strong Biomarker [1208]
GABBR1 OTU5A52J Strong Genetic Variation [327]
GABBR2 OT67RIFY Strong Genetic Variation [561]
GADD45A OTDRV63V Strong Genetic Variation [565]
GADD45GIP1 OT4IZ4TP Strong Biomarker [1209]
GALNT18 OTKIIELC Strong Genetic Variation [534]
GCHFR OTEOT8GI Strong Biomarker [504]
GDAP1 OTQE1O25 Strong Genetic Variation [534]
GDE1 OTU6FSBF Strong Biomarker [1210]
GDF11 OTOSNMND Strong Biomarker [1211]
GFRA1 OT3WBVYB Strong Genetic Variation [1212]
GNL1 OTWTVIVM Strong Genetic Variation [327]
GORASP1 OTQS91S7 Strong Biomarker [781]
GPANK1 OT1TN2KT Strong Genetic Variation [446]
GPC5 OT8NR7GC Strong Genetic Variation [324]
GPR15 OTK8674M Strong Biomarker [1213]
GPR42 OTEB0ROY Strong Biomarker [468]
GRAP2 OTS5NIZ3 Strong Biomarker [448]
GRK6 OT4LZTP9 Strong Altered Expression [287]
GSDME OT1ZWY32 Strong Biomarker [529]
GSTM2 OTG4WT05 Strong Genetic Variation [1214]
GTF2H1 OTCRXC6B Strong Altered Expression [631]
GTF2I OTUYL1TQ Strong Genetic Variation [1215]
GTF2IRD1 OTEG9KU1 Strong Genetic Variation [1215]
GZMA OT43R33L Strong Biomarker [1216]
GZMM OTEC5CWT Strong Biomarker [1217]
H4C1 OTB71W46 Strong Biomarker [1218]
HARS1 OTHOEOTS Strong Altered Expression [1219]
HARS2 OTC8X3H9 Strong Altered Expression [1219]
HAS1 OTJIAG1W Strong Altered Expression [1220]
HAVCR1 OT184CRZ Strong Genetic Variation [1129]
HCLS1 OTX7WGYN Strong Biomarker [467]
HCP5 OTV0YRI8 Strong Genetic Variation [327]
HFE OTDD93KB Strong Genetic Variation [1221]
HLA-DOA OTZE5Q7R Strong Genetic Variation [1222]
HLA-DOB OTKADDUB Strong Genetic Variation [1223]
HLA-DQA2 OT1DH0N9 Strong Genetic Variation [446]
HLA-DRA OT7KZMP2 Strong Genetic Variation [446]
HLA-DRB5 OTUX5TWM Strong Genetic Variation [1224]
HLA-E OTX1CTFB Strong Genetic Variation [1225]
HNRNPC OT47AK4C Strong Biomarker [1226]
HNRNPDL OTB3BFCV Strong Biomarker [1226]
HOXB2 OTTD6HMV Strong Biomarker [1227]
HOXC6 OTBCRAZV Strong Biomarker [1228]
HOXD10 OT0NOWU2 Strong Biomarker [1229]
HOXD9 OTZ4GVR1 Strong Altered Expression [1230]
HSD17B8 OTX1DWEF Strong Genetic Variation [327]
HSPA14 OTZCA5LK Strong Altered Expression [393]
HYAL2 OTTVINXW Strong Altered Expression [1220]
ICAM3 OTTZ5A5D Strong Genetic Variation [1049]
IER3 OTZJI5FZ Strong Altered Expression [1231]
IFI44L OTXKORJP Strong Genetic Variation [1232]
IKBKE OT5VYOSM Strong Altered Expression [1233]
IL10RA OTOX3D1D Strong Genetic Variation [1234]
IL18BP OTW0LRYZ Strong Biomarker [1235]
IL1F10 OTJAASGC Strong Altered Expression [1236]
IL1RAPL1 OTW3T4B2 Strong Biomarker [407]
IL22RA1 OTGVKLBR Strong Biomarker [1237]
IL27 OTIS3OF8 Strong Biomarker [606]
IL2RG OTRZ3OMY Strong Altered Expression [678]
ILF3 OTKMZ5K5 Strong Genetic Variation [324]
IMPACT OTQ923OB Strong Biomarker [1238]
IP6K3 OTKUIVQZ Strong Genetic Variation [446]
IRX1 OT0ZN9EJ Strong Biomarker [1239]
IRX5 OT05J514 Strong Altered Expression [1240]
ISG20 OTCWRJJW Strong Biomarker [1241]
ISL1 OTVNVKAX Strong Altered Expression [1201]
ITGAX OTOGIMHE Strong Biomarker [1242]
JAM3 OTX0F9QL Strong Altered Expression [1243]
JAZF1 OTXTYSYD Strong Genetic Variation [751]
JUNB OTG2JXV5 Strong Biomarker [530]
JUND OTNKACJD Strong Biomarker [530]
KANK4 OT5WC0Q8 Strong Altered Expression [678]
KHSRP OTDHZARB Strong Altered Expression [1244]
KIFBP OT1XADKG Strong Biomarker [1245]
KIR2DS5 OTXLEN11 Strong Biomarker [634]
KLF2 OTIP1UFX Strong Biomarker [1246]
KLRB1 OTQ2959Y Strong Altered Expression [499]
KLRC2 OTT4N86S Strong Altered Expression [1247]
KLRD1 OTMYLOV4 Strong Genetic Variation [1248]
KPNA1 OTEMVAJ6 Strong Genetic Variation [1249]
KRIT1 OT58AP1I Strong Biomarker [359]
KRT13 OTTYSKGX Strong Biomarker [1250]
LAIR2 OTKCADXC Strong Altered Expression [1251]
LAMTOR2 OTHEDISB Strong Altered Expression [1159]
LBH OT87AT1X Strong Genetic Variation [1252]
LBR OT1HG3HG Strong Altered Expression [853]
LGALS3BP OT9AGQKH Strong Biomarker [564]
LGALS8 OT71LJ8T Strong Genetic Variation [1253]
LGALS9 OT7MF91K Strong Biomarker [1254]
LHX2 OTK61NP8 Strong Altered Expression [888]
LIG4 OT40DNXU Strong Biomarker [1255]
LRIG1 OTY5HZN5 Strong Biomarker [646]
LRPAP1 OT6DVD2Q Strong Biomarker [1256]
LRRC18 OTC8M35N Strong Genetic Variation [327]
LST1 OTUVG424 Strong Altered Expression [280]
LY6G5B OTW89R8K Strong Genetic Variation [446]
LY6G5C OTC5GIUX Strong Genetic Variation [327]
LY6G6C OTV7F59X Strong Genetic Variation [446]
LY6G6D OTG75QOC Strong Genetic Variation [446]
LY6G6F OT5W9Q4B Strong Genetic Variation [327]
MAGI3 OTDJ5QUH Strong Genetic Variation [327]
MAP2K4 OTZPZX11 Strong Genetic Variation [1257]
MAST3 OT6VVQ84 Strong Altered Expression [1258]
MCCD1 OTLS95WO Strong Genetic Variation [446]
MDC1 OTEUQH4J Strong Genetic Variation [327]
MDGA2 OTIJ0T5J Strong Genetic Variation [534]
MIA3 OTBVIZQD Strong Biomarker [1259]
MIB1 OT5C404P Strong Genetic Variation [1260]
MICB OTS2DVDW Strong Biomarker [980]
MIP OTEBLU3E Strong Altered Expression [1261]
MMRN1 OT7ZNYHT Strong Altered Expression [556]
MNAT1 OTXLOYCB Strong Biomarker [504]
MOK OTQK7M9V Strong Biomarker [244]
MON2 OTCSVMAR Strong Biomarker [1262]
MOS OTNMQPFJ Strong Genetic Variation [1263]
MPG OTAHW80B Strong Biomarker [1264]
MPP1 OTA2ENZQ Strong Biomarker [1192]
MSC OTBRPZL5 Strong Biomarker [1265]
MSH5 OTDARQT3 Strong Genetic Variation [446]
MST1 OTOC4UNG Strong Altered Expression [377]
MUC5B OTPW6K5C Strong Genetic Variation [1266]
MUCL3 OTGAD3I0 Strong Genetic Variation [327]
MYBBP1A OTIVEMIU Strong Biomarker [982]
MYDGF OT9HRPL6 Strong Biomarker [606]
MYO9B OTQ94R5K Strong Genetic Variation [1267]
N4BP1 OTN2TL6N Strong Genetic Variation [534]
NAA25 OTS3QVF1 Strong Genetic Variation [1268]
NAF1 OTMJKJAK Strong Altered Expression [1269]
NAV2 OTGAOL01 Strong Genetic Variation [561]
NCF4 OTX007YL Strong Genetic Variation [1270]
NCKIPSD OT24UORN Strong Biomarker [1271]
NCOA1 OTLIUJQD Strong Biomarker [982]
NCOA5 OTOGWTWB Strong Biomarker [699]
NCOR1 OT04XNOU Strong Biomarker [862]
ND1 OTCLGIXV Strong Genetic Variation [1272]
NDST1 OT9E10W2 Strong Biomarker [1273]
NEBL OT2WH1NC Strong Genetic Variation [561]
NECAB2 OT6PITM9 Strong Genetic Variation [673]
NEU1 OTH9BY8Y Strong Altered Expression [1274]
NEU3 OTQ5PQOW Strong Biomarker [1274]
NFATC1 OT4TMERS Strong Biomarker [419]
NFYA OTWFFOVH Strong Biomarker [1275]
NKAPL OTIU393R Strong Genetic Variation [327]
NLRP6 OTEREN4W Strong Biomarker [1276]
NMT1 OT42GQ3D Strong Biomarker [1277]
NNAT OTNRLO7G Strong Biomarker [1278]
NPAS2 OTMRT2TS Strong Altered Expression [1138]
NR2C2 OTDZWVOJ Strong Biomarker [665]
NRM OTK7F9XZ Strong Genetic Variation [1279]
NUP62 OTMN63DH Strong Altered Expression [631]
NUP88 OT647WOR Strong Genetic Variation [324]
NXF1 OTEFHXG6 Strong Biomarker [1203]
OLIG3 OTU8XLAF Strong Genetic Variation [1280]
OR12D3 OTQ9XNBB Strong Genetic Variation [327]
OR2H2 OTOSTYE2 Strong Genetic Variation [327]
OR5V1 OTSYXOD6 Strong Genetic Variation [327]
OS9 OTB5B2TY Strong Genetic Variation [324]
P2RX2 OT0LF34A Strong Biomarker [691]
P2RX5 OTLBR20R Strong Biomarker [691]
P2RX6 OT1FNTXA Strong Biomarker [691]
P4HB OTTYNYPF Strong Biomarker [1192]
PADI6 OTS42I3K Strong Altered Expression [1281]
PAK3 OT80M3BV Strong Genetic Variation [838]
PAPOLA OTPHD65D Strong Genetic Variation [327]
PARD6A OTWLV3X1 Strong Altered Expression [1282]
PBX2 OTEBYCAW Strong Genetic Variation [446]
PCDH15 OTU9C2EH Strong Genetic Variation [534]
PDC OT1UUVYY Strong Biomarker [1283]
PDCD5 OT6T2DDL Strong Altered Expression [1284]
PDPN OTBUV19I Strong Biomarker [1285]
PDS5A OT34P56Z Strong Genetic Variation [327]
PELP1 OTVXQNOT Strong Biomarker [982]
PER2 OTU2B1DJ Strong Altered Expression [1286]
PGBD1 OTSJX9UU Strong Genetic Variation [327]
PHACTR3 OTUN0OAY Strong Genetic Variation [673]
PHRF1 OT21KEGX Strong Biomarker [978]
PHTF1 OTYCZ84A Strong Genetic Variation [327]
PI3 OT47MTC3 Strong Altered Expression [1287]
PIEZO1 OTBG1FU4 Strong Genetic Variation [1260]
PIK3R2 OTZSUQK5 Strong Biomarker [1288]
PIK3R3 OTXGJ8N1 Strong Biomarker [1192]
PITX2 OTWMXAOY Strong Genetic Variation [1289]
PIWIL1 OT7CRGZ3 Strong Biomarker [1290]
PIWIL2 OT1PXQIF Strong Altered Expression [1290]
PIWIL4 OTDA9MY0 Strong Biomarker [1290]
PLAAT4 OTI66SAJ Strong Biomarker [1291]
PLB1 OTZ6TTYV Strong Biomarker [1292]
PLCL1 OTJL2C79 Strong Genetic Variation [673]
PLCL2 OTK5FDF6 Strong Genetic Variation [324]
PLD3 OTL07SP2 Strong Genetic Variation [1293]
PLD4 OT5I74II Strong Biomarker [1293]
PLEK OTB73XXA Strong Biomarker [467]
POLDIP2 OT8SZSJ6 Strong Biomarker [448]
POLG2 OTDBMZJB Strong Biomarker [1192]
POT1 OTNBXJCQ Strong Altered Expression [772]
POTEF OTV3WXYE Strong Biomarker [743]
POTEM OT7L2HGH Strong Biomarker [438]
POU2F2 OTPV0J0C Strong Altered Expression [737]
POU5F1 OTDHHN7O Strong Genetic Variation [1279]
PPCDC OT9C76GS Strong Genetic Variation [839]
PPIL4 OTFTLFJS Strong Genetic Variation [324]
PPP1R10 OT7GE3BN Strong Genetic Variation [327]
PPT2 OTD5VJ9A Strong Genetic Variation [446]
PRAM1 OTZN3DWD Strong Altered Expression [1294]
PRDM10 OTDDWU5Q Strong Genetic Variation [632]
PRDM16 OT0BGA27 Strong Genetic Variation [673]
PRKN OTJBN41W Strong Biomarker [746]
PRORP OTWIS44P Strong Genetic Variation [561]
PRR12 OTY2ILFT Strong Genetic Variation [601]
PRRC2A OTBX6FM5 Strong Genetic Variation [446]
PRRT1 OTN0YIS3 Strong Genetic Variation [446]
PRRT2 OTCJUBDO Strong Altered Expression [706]
PRSS55 OTXXWI5Y Strong Biomarker [1176]
PSG5 OTHTU98X Strong Biomarker [529]
PSMA4 OTAD2XXI Strong Genetic Variation [534]
PSMD12 OTWICA51 Strong Biomarker [1192]
PSMD7 OT7PZZ4K Strong Altered Expression [643]
PSORS1C1 OT9HK436 Strong Genetic Variation [1295]
PSTPIP1 OT4PGEAB Strong Genetic Variation [1296]
PTHLH OTI1JF13 Strong Altered Expression [1297]
PTPRK OTAP5AT3 Strong Biomarker [1298]
PUF60 OTG90DYF Strong Biomarker [1299]
PXK OTSP1WLK Strong Genetic Variation [784]
PYCARD OT67RON3 Strong Biomarker [1300]
PYDC1 OTC2DD7L Strong Genetic Variation [1301]
RAB14 OTF1J0TB Strong Genetic Variation [327]
RAB8A OTPB54Y3 Strong Biomarker [467]
RABEP1 OTQROTGT Strong Genetic Variation [324]
RABEPK OTCZSREH Strong Altered Expression [643]
RAD51B OTCJVRMY Strong Genetic Variation [324]
RAP2A OT0JB5S4 Strong Biomarker [467]
RAPH1 OTMQXW7S Strong Altered Expression [1114]
RARRES2 OT1BJE8K Strong Altered Expression [1302]
RASGRP1 OTX9WN2E Strong Genetic Variation [324]
RAVER1 OTMHBTLE Strong Genetic Variation [263]
RBFOX1 OTFPKEL7 Strong Genetic Variation [324]
RBP2 OTR8QG5V Strong Biomarker [1303]
RCAN1 OT1MVXC7 Strong Genetic Variation [324]
RCHY1 OTAE7504 Strong Genetic Variation [534]
RDX OTNSYUN6 Strong Altered Expression [1304]
REG1A OTMHUH1D Strong Altered Expression [549]
RFC1 OT3L5PK3 Strong Genetic Variation [735]
RGS1 OTGXJYMG Strong Biomarker [620]
RHCE OTS18IZ5 Strong Biomarker [1202]
RIPOR2 OTXB6LIR Strong Genetic Variation [327]
RIT2 OTSNYG0D Strong Genetic Variation [534]
RMC1 OT7K8MTJ Strong Altered Expression [568]
RNASE2 OT8Z4FNE Strong Biomarker [307]
RNASEH2B OT8KHYFY Strong Genetic Variation [1171]
RNF19A OTKWCV80 Strong Biomarker [448]
RNF2 OTFPLOIN Strong Biomarker [1305]
RNF5 OTDQGI37 Strong Genetic Variation [446]
RO60 OTLGM5A8 Strong Biomarker [1045]
RPL17 OTTYMPS6 Strong Biomarker [1306]
RPL37A OTAMQLY7 Strong Genetic Variation [1212]
RPP21 OT53MDNE Strong Genetic Variation [327]
RPS18 OTFO45UM Strong Genetic Variation [327]
RPS19 OTBKGP48 Strong Biomarker [1307]
RSBN1 OT2HBRLJ Strong Genetic Variation [327]
S100A1 OT1F2G4J Strong Biomarker [721]
SAA2 OTYAVJWG Strong Altered Expression [1308]
SAMD9 OTDG48P0 Strong Altered Expression [1309]
SAR1A OTSSRVGV Strong Altered Expression [1310]
SARDH OTQ49Q27 Strong Biomarker [1311]
SATB2 OT2W80XC Strong Biomarker [1312]
SCD5 OTSSUQ3Z Strong Altered Expression [1313]
SCG2 OTXWUQQL Strong Altered Expression [1314]
SCO2 OTJQQDRS Strong Biomarker [307]
SDC3 OT1P0LJM Strong Biomarker [1080]
SDC4 OTKUVUGZ Strong Biomarker [1315]
SDF2L1 OTE7JIO2 Strong Genetic Variation [673]
SEC14L2 OTJST64D Strong Biomarker [1203]
SEMA3C OTEGUY7F Strong Biomarker [1316]
SEMA4A OT8901H3 Strong Altered Expression [1317]
SEMA6A OTDQ7QAW Strong Biomarker [1318]
SEMA7A OT0ZJK64 Strong Altered Expression [726]
SERPINA3 OT9BP2S0 Strong Biomarker [438]
SERPINF2 OTZGAF8B Strong Altered Expression [728]
SF3B6 OTPRKS6S Strong Altered Expression [1159]
SFRP2 OT8GZ0CA Strong Altered Expression [574]
SFTA2 OTVRIUIV Strong Genetic Variation [327]
SFTPA2 OT6SFOMU Strong Biomarker [1319]
SGCZ OTVGTEOD Strong Genetic Variation [1193]
SGSM3 OTIB1P8A Strong Biomarker [1320]
SH2D1A OTLU49I5 Strong Genetic Variation [1321]
SH3BP4 OTVIRKW7 Strong Biomarker [1322]
SHBG OTPWU5IW Strong Biomarker [458]
SIGIRR OTNC3XFD Strong Biomarker [407]
SIGLEC7 OTNDLURR Strong Altered Expression [1244]
SLC12A9 OTR7VRAK Strong Altered Expression [1323]
SLC16A4 OT1YXBKC Strong Biomarker [733]
SLPI OTUNFUU8 Strong Altered Expression [384]
SLURP1 OT89YD2E Strong Biomarker [1324]
SMG7 OTZDB0JX Strong Genetic Variation [601]
SOAT1 OTB4Y5RJ Strong Biomarker [1325]
SOCS2 OTBPNKJQ Strong Biomarker [1326]
SOD3 OTIOZQAB Strong Biomarker [1327]
SPATA2 OTOA45GL Strong Biomarker [1306]
SPRED2 OTUX685J Strong Genetic Variation [324]
SPRY2 OTH0CRCZ Strong Altered Expression [1328]
SPSB1 OTGY26U4 Strong Genetic Variation [534]
SPZ1 OTQH8HJ5 Strong Biomarker [1176]
SRL OT7IEBWZ Strong Biomarker [1311]
SRP54 OT9SGF3X Strong Genetic Variation [1329]
ST6GAL1 OT7US3NO Strong Biomarker [1274]
ST6GALNAC5 OTH91ETM Strong Biomarker [529]
STAG1 OT564IX4 Strong Genetic Variation [324]
STAT5B OTZVPEBT Strong Biomarker [1330]
STEAP4 OTFTLAEZ Strong Altered Expression [1331]
STK19 OTYM6437 Strong Genetic Variation [446]
SUMO1 OTJFD4P5 Strong Altered Expression [1002]
SUOX OTEJQ9FC Strong Genetic Variation [324]
SYNGAP1 OT41HVYQ Strong Genetic Variation [327]
SYNM OTOI8TRJ Strong Biomarker [1332]
SYT1 OTVTPOI6 Strong Biomarker [781]
TAC1 OTM842YW Strong Biomarker [1333]
TADA1 OTV9RKSL Strong Genetic Variation [1117]
TAGAP OTHJNNO2 Strong Biomarker [1334]
TAP2 OTWSYFI7 Strong Genetic Variation [1223]
TAPBP OTL81AVZ Strong Genetic Variation [446]
TAX1BP3 OTQ6IB4T Strong Biomarker [1335]
TBC1D9 OTSSCTB5 Strong Genetic Variation [1336]
TBX3 OTM64N7K Strong Biomarker [1337]
TBX5 OT70PISV Strong Biomarker [1338]
TCEA1 OTBFO594 Strong Biomarker [1339]
TCF19 OT7NKLF9 Strong Genetic Variation [327]
TCN2 OT41D0L3 Strong Genetic Variation [1340]
TCP11L1 OTL9X02U Strong Genetic Variation [534]
TFDP1 OT6RZ7VT Strong Biomarker [1341]
TFF3 OTJJDRTU Strong Altered Expression [347]
TFPI2 OTZCRWOR Strong Biomarker [529]
TIA1 OTGPN3P8 Strong Biomarker [543]
TIMELESS OTD8DCBJ Strong Genetic Variation [1129]
TIMP1 OTOXC51H Strong Biomarker [1342]
TIMP3 OTDGQAD1 Strong Biomarker [1132]
TINAGL1 OTZZO56M Strong Biomarker [1343]
TLR10 OTQ1KVJO Strong Altered Expression [1344]
TM7SF2 OTILU5S7 Strong Altered Expression [454]
TMEM147 OTMKZ4PV Strong Biomarker [1345]
TMEM158 OT0KUBBI Strong Altered Expression [1346]
TMEM179 OTHB07OM Strong Genetic Variation [673]
TMEM235 OTNHWPUE Strong Genetic Variation [673]
TMEM60 OTRJU667 Strong Biomarker [1347]
TMPO OTL68EL4 Strong Biomarker [467]
TNFRSF6B OTKAN9G7 Strong Altered Expression [1081]
TNIP1 OTRAOTEW Strong Genetic Variation [601]
TNPO3 OTOT3HH0 Strong Genetic Variation [601]
TPI1 OT14KP4B Strong Genetic Variation [1129]
TRAF3IP2 OTLLZERL Strong Biomarker [1295]
TREX1 OTQG7K12 Strong Biomarker [1348]
TRIM10 OTEO4UCZ Strong Genetic Variation [327]
TRIM15 OTNYAKP6 Strong Genetic Variation [327]
TRIM26 OTS0DJIP Strong Genetic Variation [327]
TRIM3 OT704FQ0 Strong Altered Expression [1349]
TRIM31 OT7VW6RP Strong Genetic Variation [327]
TRIM39 OTESLVP9 Strong Genetic Variation [327]
TRIM40 OTLKKKA5 Strong Genetic Variation [327]
TRPS1 OT7XPPEL Strong Genetic Variation [534]
TSC22D3 OT03UM03 Strong Biomarker [1350]
TSPAN5 OTHCCHHV Strong Genetic Variation [534]
ADAMTS9 OTV3Q0DS Definitive Altered Expression [1351]
ADGRG1 OTQBB8NT Definitive Altered Expression [1352]
AFF1 OTT2C78E Definitive Biomarker [1353]
AIMP1 OTTA5C3U Definitive Altered Expression [1354]
AMH OT5FH4BD Definitive Biomarker [1355]
ANXA4 OTUCRYXL Definitive Biomarker [1356]
ARPC1A OTAEEXGQ Definitive Altered Expression [1357]
ASPSCR1 OTXTOD10 Definitive Biomarker [426]
B4GALT1 OTBCXEK7 Definitive Biomarker [1358]
BCL2L12 OTS6IFZY Definitive Altered Expression [1359]
CCDC134 OT70OQQV Definitive Biomarker [1360]
CCN4 OT69BER9 Definitive Biomarker [1361]
CD109 OTDADBM4 Definitive Biomarker [1362]
CD2AP OTC76KQM Definitive Genetic Variation [1363]
CD79A OTOJC8DV Definitive Altered Expression [936]
CDKAL1 OTA0SGNE Definitive Genetic Variation [1364]
CEACAM8 OTLL9WWO Definitive Biomarker [1365]
CELF2 OTLJJ4VT Definitive Genetic Variation [477]
CLDN1 OT27KV99 Definitive Altered Expression [1366]
CLDN7 OTNE0XHQ Definitive Altered Expression [1366]
CNN2 OTH3CSXA Definitive Biomarker [1367]
COL4A1 OTL6D1YE Definitive Genetic Variation [839]
COL4A5 OTHG60RE Definitive Genetic Variation [1368]
COMMD1 OT7WUD5R Definitive Altered Expression [1369]
CRIP3 OT7H1YOY Definitive Biomarker [1161]
CSRP3 OTECBJMV Definitive Biomarker [1161]
CYBA OT16N9ZO Definitive Biomarker [379]
CYP4V2 OTQKNK0D Definitive Biomarker [1370]
DEF6 OTIRBYVK Definitive Altered Expression [1371]
DSPP OT1TYNDN Definitive Genetic Variation [1372]
DUSP2 OTH54FMR Definitive Biomarker [785]
DUSP22 OTEZ3U85 Definitive Genetic Variation [1373]
DVL2 OTMNYNCM Definitive Biomarker [1374]
EFNB2 OT0DCUOM Definitive Altered Expression [927]
EMD OTR8ZANE Definitive Biomarker [1375]
EOMES OTB9VQFA Definitive Biomarker [1376]
EPB41L5 OTPPQPLU Definitive Biomarker [1377]
FBXW8 OTJG15EO Definitive Genetic Variation [477]
FGF9 OT2SKDGM Definitive Biomarker [811]
GARS1 OT5B6R9Y Definitive Biomarker [829]
GIT2 OTQ2EQJ1 Definitive Genetic Variation [1378]
GYS1 OTJZJRWK Definitive Altered Expression [1379]
HRG OTPLUFOG Definitive Altered Expression [1380]
IBTK OTB2GM4G Definitive Biomarker [1381]
IFIT1 OTXOQDSG Definitive Biomarker [1382]
IFNL2 OT4BMJF7 Definitive Altered Expression [1383]
IL17RD OTKD9XST Definitive Altered Expression [1384]
IL26 OT2WYCW4 Definitive Biomarker [1385]
IRAK2 OT6Y1QZN Definitive Genetic Variation [1386]
ITIH4 OT460OO1 Definitive Altered Expression [1387]
ITSN1 OT8YF3S5 Definitive Altered Expression [1388]
JTB OT314JB6 Definitive Altered Expression [684]
KAT2A OTN0W2SW Definitive Biomarker [1389]
LAT OTZC1XZ1 Definitive Biomarker [792]
LPIN2 OTRRTMXX Definitive Altered Expression [1390]
LRRC31 OT7VCU13 Definitive Biomarker [869]
MAP1LC3A OTPMGIU4 Definitive Altered Expression [1391]
MAP1LC3B OTUYHB84 Definitive Genetic Variation [1392]
MARCO OT0NW2Q0 Definitive Biomarker [1393]
MARF1 OTYRJ4V2 Definitive Altered Expression [1394]
MARK1 OTP7KL47 Definitive Biomarker [1395]
MASP1 OTWWCNZP Definitive Biomarker [1396]
MBNL1 OTOV7J85 Definitive Altered Expression [1397]
METTL3 OTSXP1M3 Definitive Altered Expression [1398]
MTMR3 OTBIT23O Definitive Altered Expression [1392]
NCF2 OTAUW7L2 Definitive Genetic Variation [601]
NCR3 OT20M764 Definitive Altered Expression [1399]
NUCB2 OTHO6JWN Definitive Altered Expression [1400]
OCLN OTSUTVWL Definitive Altered Expression [1366]
OPN1LW OTFNUZ7O Definitive Biomarker [1401]
PAEP OTQA0NV4 Definitive Genetic Variation [1402]
PAG1 OTFOJUIQ Definitive Biomarker [1401]
PARP9 OT7K4494 Definitive Posttranslational Modification [1403]
PBOV1 OT67PERT Definitive Biomarker [1404]
PCBP1 OTHN0TD7 Definitive Biomarker [1405]
PCBP4 OTDLL4NB Definitive Biomarker [1401]
PHEX OTG7N3J7 Definitive Biomarker [1406]
PLCG2 OTGVC9MY Definitive Biomarker [1407]
PPAN OT0UFQBZ Definitive Biomarker [818]
PPBP OT1FHGQS Definitive Altered Expression [1408]
PPIG OTZ8BTTM Definitive Genetic Variation [1409]
PPP1R11 OTSHYPPW Definitive Biomarker [1410]
PRDM8 OTRA3265 Definitive Altered Expression [1411]
PROP1 OT8GF6N8 Definitive Altered Expression [1412]
PSMG1 OTZ5I6UM Definitive Biomarker [785]
RASL12 OTNAK9X4 Definitive Biomarker [1413]
RCAN3 OTTS3CQA Definitive Biomarker [1414]
RGCC OTYJMLWM Definitive Biomarker [811]
RMDN1 OTE1NB6U Definitive Biomarker [631]
RMDN2 OTK5WSFI Definitive Biomarker [631]
RMDN3 OTKO7AUM Definitive Biomarker [631]
RTL1 OTOT33IM Definitive Biomarker [1415]
S100A10 OTI71243 Definitive Biomarker [472]
SEMA6B OT3VVVUO Definitive Biomarker [1213]
SESN2 OT889IXY Definitive Biomarker [1416]
SETMAR OTE2MIMZ Definitive Biomarker [1415]
SIGLEC9 OTZC7SIM Definitive Biomarker [1417]
SNW1 OTKWG3PS Definitive Biomarker [1418]
SPESP1 OTWXKKTJ Definitive Biomarker [1419]
SRGAP1 OTL89HGW Definitive Genetic Variation [1420]
SYBU OT3FQV7N Definitive Biomarker [631]
TRAF3 OT5TQBGV Definitive Biomarker [1421]
TTC38 OTKE53HT Definitive Biomarker [1390]
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References

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3 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
4 FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (BLA) 103950.
5 2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.
6 ClinicalTrials.gov (NCT02317627) Study of of KD025 in Subjects With Psoriasis Vulgaris Who Failed First-Line Therapy. U.S. National Institutes of Health.
7 Betamethasone FDA Label
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12 Cortisone acetate FDA Label
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19 ClinicalTrials.gov (NCT02390700) Observational Study of Golimumab Intravenous Infusion
20 Hydrocortisone FDA Label
21 ClinicalTrials.gov (NCT00029042) Infliximab to Treat Children With Juvenile Rheumatoid Arthritis
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26 Prednisone FDA Label
27 Protein binding of tolmetin. Clin Pharmacol Ther. 1978 Dec;24(6):694-705.
28 ClinicalTrials.gov (NCT01359943) Efficacy, Safety and Tolerability of Secukinumab in Patients With Rheumatoid Arthritis Taking Methotrexate
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30 Sirolimus FDA Label
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38 Triamcinolone FDA Label
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42 ClinicalTrials.gov (NCT02137226) BI 695501 Compared to Adalimumab in Patients With Active Rheumatoid Arthritis. U.S. National Institutes of Health.
43 ClinicalTrials.gov (NCT01626677) Follow-Up Study of CARTISTEM Versus Microfracture for the Treatment of Knee Articular Cartilage Injury or Defect. U.S. National Institutes of Health.
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48 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034367)
49 ClinicalTrials.gov (NCT04991753) A Multicenter, Randomized, Double-blind, Parallel-group, Placebo-controlled, Proof-of-concept Study Evaluating the Efficacy and Safety of Nipocalimab Administered Intravenously in Participants With Active Rheumatoid Arthritis Despite Standard Therapy. U.S.National Institutes of Health.
50 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
51 ClinicalTrials.gov (NCT02073279) Efficacy and Safety Study as Monotherapy of SA237 to Treat NMO and NMOSD. U.S. National Institutes of Health.
52 ClinicalTrials.gov (NCT01689532) A Study of CNTO 136 (Sirukumab) Administered Subcutaneously in Japanese Patients With Active Rheumatoid Arthritis Unresponsive to Methotrexate or Sulfasalazine. U.S. National Institutes of Health.
53 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2395).
54 ClinicalTrials.gov (NCT01130246) VISTA-16 Trial: Evaluation of Safety and Efficacy of Short-term A-002 Treatment in Subjects With Acute Coronary Syndrome. U.S. National Institutes of Health.
55 ClinicalTrials.gov (NCT01925157) A Study of LY3090106 in Healthy Participants and Participants With Rheumatoid Arthritis (RA). U.S. National Institutes of Health.
56 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8309).
57 Clinical pipeline report, company report or official report of CreaGene Inc.
58 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6059).
59 Clinical pipeline report, company report or official report of Klus Pharma
60 ClinicalTrials.gov (NCT04888585) A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABBV-154 in Subjects With Moderately to Severely Active Rheumatoid Arthritis With Inadequate Response to Biologic and/or Targeted Synthetic Disease-Modifying Anti-Rheumatic Drugs (b/tsDMARDs). U.S.National Institutes of Health.
61 ClinicalTrials.gov (NCT02349451) A Phase 2 Study to Investigate the Safety, Tolerability and Efficacy of ABT-122 in Subjects With Active Psoriatic Arthritis Who Have an Inadequate Response to Methotrexate. U.S. National Institutes of Health.
62 ClinicalTrials.gov (NCT00141934) A Multicentre Trial to Determine the Efficacy of AD 452 in RA Subjects.. U.S. National Institutes of Health.
63 ClinicalTrials.gov (NCT00626275) Study Evaluating the Analgesic Efficacy and Safety of ADL5859 in Subjects With Rheumatoid Arthritis. U.S. National Institutes of Health.
64 ClinicalTrials.gov (NCT00902369) A Study of AK106-001616 in Patients With Rheumatoid Arthritis (RA). U.S. National Institutes of Health.
65 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
66 Clinical pipeline report, company report or official report of Celimmune.
67 Clinical pipeline report, company report or official report of Genentech (2011).
68 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6482).
69 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
70 ClinicalTrials.gov (NCT01552681) Baminercept in Sj ren's Syndrome. U.S. National Institutes of Health.
71 ClinicalTrials.gov (NCT02009761) Multiple Rising Does Study (Subcutaneous Doses) of BI 655064 in Male and Female Patients With Chronic Primary Immune Thrombocytopenic Purpura (ITP).. U.S. National Institutes of Health.
72 ClinicalTrials.gov (NCT01930890) BIIB023 Long-Term Extension Study in Subjects With Lupus Nephritis. U.S. National Institutes of Health.
73 ClinicalTrials.gov (NCT01404585) Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis. U.S. National Institutes of Health.
74 ClinicalTrials.gov (NCT01545050) Dose Ranging Study of BMS-945429 in Subjects With Moderate to Severe Crohn's Disease. U.S. National Institutes of Health.
75 ClinicalTrials.gov (NCT04186871) A Randomized, Placebo-Controlled, Double-Blind, Multicenter Study to Assess the Efficacy and Safety of Branebrutinib Treatment in Subjects With Active Systemic Lupus Erythematosus or Primary Sj?gren's Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Subjects With Active Rheumatoid Arthritis. U.S.National Institutes of Health.
76 ClinicalTrials.gov (NCT01999192) Study to Investigate the Safety and Efficacy of Tregalizumab in Subjects (MTX-IR) With Active Rheumatoid Arthritis. U.S. National Institutes of Health.
77 ClinicalTrials.gov (NCT01310114) Study of Human Placenta-derived Cells (PDA001) to Evaluate the Safety and Effectiveness for Patients With Ischemic Stroke. U.S. National Institutes of Health.
78 Clinical pipeline report, company report or official report of Genosco
79 ClinicalTrials.gov (NCT02291029) Safety, Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Primary Sj ren's Syndrome. U.S. National Institutes of Health.
80 ClinicalTrials.gov (NCT01116141) A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA). U.S. National Institutes of Health.
81 Anti-Interleukin-23 Monoclonal Antibody Guselkumab Shows Significant Efficacy in Treatment of Moderate to Severe Plaque Psoriasis. Janssen Research & Development, LLC (Janssen). Mar 24, 2014.
82 ClinicalTrials.gov (NCT01909427) An Efficacy And Safety Study of CNTO 6785 In Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy. U.S. National Institutes of Health.
83 ClinicalTrials.gov (NCT04163991) A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Mechanistic Insight and Dosage Optimization Study of the Efficacy and Safety of VIB4920 in Patients With Rheumatoid Arthritis (RA). U.S.National Institutes of Health.
84 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016731)
85 Clinical pipeline report, company report or official report of EQRx
86 Effects of the COX-2 inhibitor FK3311 on ischemia - reperfusion injury in the rat lung. J Invest Surg. 2007 May-Jun;20(3):175-80.
87 ClinicalTrials.gov (NCT02279602) Rollover Protocol for Subjects Who Have Responded on Study 4218s - A Phase 2 Study. U.S. National Institutes of Health.
88 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7913).
89 ClinicalTrials.gov (NCT05165771) A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase 2 Proof-of-Concept Study to Evaluate Safety, Tolerability, and Efficacy of GS-5718 on Background Therapy With Conventional Synthetic Disease-modifying Antirheumatic Drug(s) (csDMARDs) in Participants With Active Rheumatoid Arthritis Who Have an Inadequate Response to Biologic DMARD(s) Treatment. U.S.National Institutes of Health.
90 ClinicalTrials.gov (NCT00674635) Phase II Study Evaluating the Safety and Efficacy of GSK315234A in Patients With Rheumatoid Arthritis. U.S. National Institutes of Health.
91 The therapeutic mavericks: Potent immunomodulating chaperones capable of treating human diseases. J Cell Mol Med. 2023 Feb;27(3):322-339.
92 ClinicalTrials.gov (NCT02295865) A Study to Evaluate Safety and Efficacy of Toreforant (JNJ-38518168) in Participants With Moderate to Severe Plaque-type Psoriasis. U.S. National Institutes of Health.
93 Clinical pipeline report, company report or official report of KaloBios Pharmaceuticals.
94 ClinicalTrials.gov (NCT05198310) A Phase 2, Multicenter, Randomized, Double-blind, Placebo Controlled Study to Assess the Safety, Pharmacokinetics, and Efficacy of KPL-404 in Subjects With Moderate to Severe Active Rheumatoid Arthritis With Inadequate Response or Intolerance to at Least One Biologic Disease-modifying Anti-rheumatic Drug or a Janus Kinase Inhibitor. U.S.National Institutes of Health.
95 ClinicalTrials.gov (NCT00903383) Study of LX3305 in Subjects With Active Rheumatoid Arthritis on Stable Methotrexate. U.S. National Institutes of Health.
96 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7785).
97 Clinical pipeline report, company report or official report of Sanofi Pasteur.
98 ClinicalTrials.gov (NCT01497223) MGCD290 and Fluconazole Versus Fluconazole Alone for the Treatment of Moderate to Severe Vulvovaginal Candidiasis. U.S. National Institutes of Health.
99 ClinicalTrials.gov (NCT01569152) Safety and Efficacy of MK-8457 and Methotrexate (MTX) in Participants With Active Rheumatoid Arthritis Despite MTX Therapy (MK-8457-008). U.S. National Institutes of Health.
100 ClinicalTrials.gov (NCT01408602) A Study of Two Doses of MRC375 in Moderate to Severe Rheumatoid Arthritis Patients. U.S. National Institutes of Health.
101 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030434)
102 Clinical pipeline report, company report or official report of Innate Pharma.
103 Complement-targeted therapeutics. Nat Biotechnol. 2007 Nov;25(11):1265-75.
104 ClinicalTrials.gov (NCT01226745) A Safety and Efficacy Extension Study of ONO-4641 (MSC2430913A) in Patients With Relapsing-Remitting Multiple Sclerosis. U.S. National Institutes of Health.
105 ClinicalTrials.gov (NCT04333147) Long-term Safety and Efficacy of GSK3196165 (Otilimab) in the Treatment of Rheumatoid Arthritis (RA). U.S. National Institutes of Health.
106 ClinicalTrials.gov (NCT01063803) Study Evaluating Long-Term Safety Of ATN-103 In Subjects With Rheumatoid Arthritis. U.S. National Institutes of Health.
107 ClinicalTrials.gov (NCT01732211) A Phase 2, Safety, Tolerability, and Efficacy Study of PD 0360324 in Chronic Pulmonary Sarcoidosis. U.S. National Institutes of Health.
108 ClinicalTrials.gov (NCT00537667) The SPECTRA Study. U.S. National Institutes of Health.
109 ClinicalTrials.gov (NCT05516758) A Phase 2b, Double-Blind, Placebo-Controlled Study to Evaluate Peresolimab in Adult Participants With Moderately-to-Severely Active Rheumatoid Arthritis. U.S.National Institutes of Health.
110 ClinicalTrials.gov (NCT00938587) A Study Of PF-04171327 In The Treatment Of The Signs And Symptoms Of Rheumatoid Arthritis. U.S. National Institutes of Health.
111 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
112 ClinicalTrials.gov (NCT00369928) Evaluation of 2 Oral Doses of PG-760564 in Rheumatoid Arthritis (RA) Patients Receiving Methotrexate. U.S. National Institutes of Health.
113 Effect of food and gender on the pharmacokinetics of RP 73401, a phosphodiesterase IV inhibitor. Int J Clin Pharmacol Ther. 2000 Dec;38(12):588-94.
114 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6467).
115 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6040).
116 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800040434)
117 ClinicalTrials.gov (NCT00525213) Study to Evaluate the Efficacy and Safety of Orally Administered Rob 803 When Added to Methotrexate. U.S. National Institutes of Health.
118 CaMKII inhibitors: from research tools to therapeutic agents. Front Pharmacol. 2014; 5: 21.
119 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015778)
120 ClinicalTrials.gov (NCT01008852) Study Evaluating The Efficacy And Safety Of SBI-087 In Seropositive Subjects With Active Rheumatoid Arthritis. U.S. National Institutes of Health.
121 Both the immunosuppressant SR31747 and the antiestrogen tamoxifen bind to an emopamil-insensitive site of mammalian Delta8-Delta7 sterol isomerase. J Pharmacol Exp Ther. 1998 Jun;285(3):1296-302.
122 ClinicalTrials.gov (NCT00502515) Dose-effect of SSR180575 in Diabetic Neuropathy. U.S. National Institutes of Health.
123 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 662).
124 A phase 1/2A trial of STA 5326, an oral interleukin-12/23 inhibitor, in patients with active moderate to severe Crohn's disease. Inflamm Bowel Dis. 2006 Jul;12(7):558-65.
125 ClinicalTrials.gov (NCT00760864) Safety and Efficacy of TAK-715 in Subjects With Rheumatoid Arthritis. U.S. National Institutes of Health.
126 ClinicalTrials.gov (NCT00760968) Efficacy and Safety of TAK-783 in Subjects With Rheumatoid Arthritis. U.S. National Institutes of Health.
127 2011 Pipeline of 4SC AG.
128 ClinicalTrials.gov (NCT02518620) An Open-Label Extension Study Assessing the Long-Term Efficacy and Safety of ALX-0061 in Subjects With Rheumatoid Arthritis. U.S. National Institutes of Health.
129 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5719).
130 ClinicalTrials.gov (NCT02867098) XmAb5871 Bioavailability Study
131 ClinicalTrials.gov (NCT04247815) A Phase 2a, Randomized, Investigator and Patient-blind, Sponsor-unblinded, Parallel Group, Placebo-controlled Study of ATI-450 Plus Methotrexate (MTX) vs MTX Alone in Patients With Moderate to Severe Active Rheumatoid Arthritis. U.S.National Institutes of Health.
132 LD-aminopterin in the canine homologue of human atopic dermatitis: a randomized, controlled trial reveals dosing factors affecting optimal therapy. PLoS One. 2014 Sep 25;9(9):e108303.
133 Emerging drugs for psoriasis. Expert Opin Emerg Drugs. 2009 Mar;14(1):145-63.
134 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
135 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034187)
136 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018258)
137 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031251)
138 ClinicalTrials.gov (NCT02052375) A Study To Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of ASP2408 After Multiple Dose Subcutaneous Injections in Patients With RheumatoidArthritis on Methotrexate. U.S. National Institutes of Health.
139 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
140 Antiarthritic profile of BF-389--a novel anti-inflammatory agent with low ulcerogenic liability. Agents Actions. 1992 Sep;37(1-2):90-8.
141 ClinicalTrials.gov (NCT03828344) A Phase 1 Randomized, Placebo-Controlled, Double-Blind Study of the Safety and Tolerability of a Single Intravenous Infusion of BX-U001, a Human Umbilical Cord Tissue Derived Mesenchymal Stem Cell Product, for Refractory Rheumatoid Arthritis. U.S.National Institutes of Health.
142 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800039530)
143 Clinical pipeline report, company report or official report of Evotec.
144 ClinicalTrials.gov (NCT00539760) A Phase I Rheumatoid Arthritis Study in Healthy Volunteers. U.S. National Institutes of Health.
145 Clinical pipeline report, company report or official report of GlaxoSmithKline.
146 ClinicalTrials.gov (NCT01765478) Safety,PK/PD, Food Effect Study of Orally Administered HM71224 in Healthy Adult Male Volunteers. U.S. National Institutes of Health.
147 ClinicalTrials.gov (NCT05533372) Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IA-14069 in Healthy Subjects, With an Extension to Explore Any Drug-Drug Interaction Potential With Methotrexate (Part 1), and in Patients With Rheumatoid Arthritis, With Preliminary Assessment of Efficacy in Patients (Part 2). U.S.National Institutes of Health.
148 ClinicalTrials.gov (NCT04985812) A Multicenter, Double-blind, Placebo-controlled, Randomized, Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of JNJ-67484703 in Participants With Active Rheumatoid Arthritis. U.S.National Institutes of Health.
149 ClinicalTrials.gov (NCT05019950) A Randomized, Placebo-Controlled, Double-Blind, Single-Center Study to Evaluate Safety Tolerability and Pharmacokinetics of Oral NIM-1324 in Healthy Adult Male and Female Volunteers. U.S.National Institutes of Health.
150 ClinicalTrials.gov (NCT01559103) Study to Assess the Safety and Tolerability of MEDI5117 in Rheumatoid Arthritis Patients. U.S. National Institutes of Health.
151 Glucocorticoid receptor nitration leads to enhanced anti-inflammatory effects of novel steroid ligands. J Immunol. 2003 Sep 15;171(6):3245-52.
152 ClinicalTrials.gov (NCT04286789) A Randomized, Double-blind, Parallel, Vehicle Controlled, Repeat Dose Comparative Phase 1b Study to Evaluate the Safety, Tolerability and Pharmacokinetics of ORTD-1 in Rheumatoid Arthritis Patients With Mild Disease Managed With DMARDs. U.S.National Institutes of Health.
153 ClinicalTrials.gov (NCT01284036) A Single Dose Study Of The Safety And Investigational Product Level Measurement In Healthy Subjects. U.S. National Institutes of Health.
154 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032595)
155 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030399)
156 Subcutaneous injections of low doses of humanized anti-CD20 veltuzumab: a phase I study in chronic lymphocytic leukemia. Leuk Lymphoma. 2015 Oct 19:1-9.
157 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029914)
158 Velcura Therapeutics, Inc. to Begin Clinical Trials in Rheumatoid Arthritis Patients. Velcura Therapeutics, Inc. JANUARY 07, 2009.
159 Effects of the immunomodulator, VGX-1027, in endotoxin-induced uveitis in Lewis rats. Br J Pharmacol. 2008 Nov;155(5):722-30.
160 AZ-4217: a high potency BACE inhibitor displaying acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice. J Neurosci. 2013 Jun 12;33(24):10075-84.
161 Cathepsin B and L inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2017 Jun;27(6):643-656.
162 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000926)
163 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002733)
164 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020487)
165 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001452)
166 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026002)
167 Emerging drugs for idiopathic thrombocytopenic purpura in adults. Expert Opin Emerg Drugs. 2008 Jun;13(2):237-54.
168 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015375)
169 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007279)
170 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6155).
171 Clinical pipeline report, company report or official report of Galapagos.
172 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005016)
173 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007359)
174 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800038032)
175 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013426)
176 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002363)
177 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023346)
178 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027730)
179 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022053)
180 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018538)
181 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030380)
182 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010176)
183 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007225)
184 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016746)
185 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015041)
186 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019215)
187 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023206)
188 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009741)
189 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7687).
190 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017126)
191 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017125)
192 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027710)
193 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020402)
194 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002367)
195 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013227)
196 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800036376)
197 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029003)
198 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030004)
199 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025504)
200 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017105)
201 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001478)
202 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006813)
203 Lysosomes as a therapeutic target. Nat Rev Drug Discov. 2019 Dec;18(12):923-948.
204 Emerging drugs for the treatment of chronic obstructive pulmonary disease. Expert Opin Emerg Drugs. 2006 May;11(2):275-91.
205 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000969)
206 Circadian rhythm as a therapeutic target. Nat Rev Drug Discov. 2021 Apr;20(4):287-307.
207 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019127)
208 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019129)
209 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016328)
210 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7686).
211 Role of leukotrienes on coronary vasoconstriction in isolated hearts of arthritic rats: effect of in vivo treatment with CI-986, a dual inhibitor of cyclooxygenase and lipoxygenase. Pharmacology. 2000 Jan;60(1):41-6.
212 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007275)
213 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6509).
214 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007983)
215 Antiarthritis effect of a novel Bruton's tyrosine kinase (BTK) inhibitor in rat collagen-induced arthritis and mechanism-based pharmacokinetic/pharmacodynamic modeling: relationships between inhibition of BTK phosphorylation and efficacy. J Pharmacol Exp Ther. 2011 Jul;338(1):154-63.
216 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010855)
217 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002734)
218 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021746)
219 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002350)
220 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001772)
221 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013076)
222 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005018)
223 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029797)
224 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006085)
225 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000933)
226 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001260)
227 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007333)
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229 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005582)
230 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003820)
231 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005488)
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234 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2294).
235 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2743).
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237 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1870).
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383 Role of allograft inflammatory factor-1 in bleomycin-induced lung fibrosis.Biochem Biophys Res Commun. 2018 Jan 8;495(2):1901-1907. doi: 10.1016/j.bbrc.2017.12.035. Epub 2017 Dec 7.
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426 Sarcopenia in osteoarthritis and rheumatoid arthritis: The association with self-reported fatigue, physical function and obesity.PLoS One. 2019 Jun 6;14(6):e0217462. doi: 10.1371/journal.pone.0217462. eCollection 2019.
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433 Vasoactive intestinal peptide is required in the maintenance of immune regulatory competency of immune regulatory monocytes.Clin Exp Immunol. 2019 May;196(2):276-286. doi: 10.1111/cei.13259. Epub 2019 Jan 30.
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479 The rheumatoid synovial environment alters fatty acid metabolism in human monocytes and enhances CCL20 secretion.Rheumatology (Oxford). 2020 Apr 1;59(4):869-878. doi: 10.1093/rheumatology/kez378.
480 An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium.Cytokine. 2017 Sep;97:133-140. doi: 10.1016/j.cyto.2017.05.023.
481 Overweight/obesity affects histological features and inflammatory gene signature of synovial membrane of Rheumatoid Arthritis.Sci Rep. 2019 Jul 18;9(1):10420. doi: 10.1038/s41598-019-46927-w.
482 Role of microRNA-26a in cartilage injury and chondrocyte proliferation and apoptosis in rheumatoid arthritis rats by regulating expression of CTGF.J Cell Physiol. 2020 Feb;235(2):979-992. doi: 10.1002/jcp.29013. Epub 2019 Jul 2.
483 Potent and selective CC chemokine receptor 1 antagonists labeled with carbon-13, carbon-14, and tritium.J Labelled Comp Radiopharm. 2018 May 15. doi: 10.1002/jlcr.3635. Online ahead of print.
484 Upregulated expression of CCR3 in rheumatoid arthritis and CCR3-dependent activation of fibroblast-like synoviocytes.Cell Biol Toxicol. 2017 Feb;33(1):15-26. doi: 10.1007/s10565-016-9356-7. Epub 2016 Aug 5.
485 Comparison of rheumatoid arthritis (RA) and osteoarthritis (OA) based on microarray profiles of human joint fibroblast-like synoviocytes.Cell Biochem Funct. 2019 Jan;37(1):31-41. doi: 10.1002/cbf.3370. Epub 2018 Nov 23.
486 The chemokine receptor CCR7 is a promising target for rheumatoid arthritis therapy.Cell Mol Immunol. 2019 Oct;16(10):791-799. doi: 10.1038/s41423-018-0056-5. Epub 2018 Jul 4.
487 Abrogation of CC chemokine receptor 9 ameliorates collagen-induced arthritis of mice.Arthritis Res Ther. 2014 Sep 24;16(5):445. doi: 10.1186/s13075-014-0445-9.
488 Mining functional gene modules linked with rheumatoid arthritis using a SNP-SNP network.Genomics Proteomics Bioinformatics. 2012 Feb;10(1):23-34. doi: 10.1016/S1672-0229(11)60030-2.
489 Psoriatic Synovitis: Singularity and Potential Clinical Implications.Front Med (Lausanne). 2019 Feb 11;6:14. doi: 10.3389/fmed.2019.00014. eCollection 2019.
490 Resistin Gene Expression is Downregulated in CD4(+) THelper Lymphocytes and CD14(+) Monocytes in Rheumatoid Arthritis Responding to TNF- Inhibition.Scand J Immunol. 2016 Oct;84(4):229-36. doi: 10.1111/sji.12464.
491 A candidate gene study identifies a haplotype of CD2 as novel susceptibility factor for systemic sclerosis.Clin Exp Rheumatol. 2016 Sep-Oct;34 Suppl 100(5):43-48. Epub 2016 Jul 1.
492 CD248 and its cytoplasmic domain: a therapeutic target for arthritis.Arthritis Rheum. 2010 Dec;62(12):3595-606. doi: 10.1002/art.27701.
493 B7-H3 modulates endothelial cell angiogenesis through the VEGF cytokine.Immunol Res. 2019 Jun;67(2-3):202-211. doi: 10.1007/s12026-019-09084-w.
494 Potential therapeutic effects of cyanidin-3-O-glucoside on rheumatoid arthritis by relieving inhibition of CD38+ NK cells on Treg cell differentiation.Arthritis Res Ther. 2019 Oct 28;21(1):220. doi: 10.1186/s13075-019-2001-0.
495 Association of CD4 enhancer gene polymorphisms with rheumatoid arthritis and systemic lupus erythematosus in Taiwan.J Rheumatol. 2008 Nov;35(11):2113-8. doi: 10.3899/jrheum.070993.
496 Targeted delivery of hyaluronic acid-coated solid lipid nanoparticles for rheumatoid arthritis therapy.Drug Deliv. 2018 Nov;25(1):716-722. doi: 10.1080/10717544.2018.1447050.
497 Correlation between cellular expression of complement regulatory proteins with depletion and repopulation of B-lymphocytes in peripheral blood of patients with rheumatoid arthritis treated with rituximab.Rev Bras Reumatol Engl Ed. 2017 Sep-Oct;57(5):385-391. doi: 10.1016/j.rbre.2016.09.007. Epub 2016 Oct 18.
498 Promotion of osteoclastogenesis by IL-26 in rheumatoid arthritis.Arthritis Res Ther. 2019 Dec 12;21(1):283. doi: 10.1186/s13075-019-2070-0.
499 Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis.Arthritis Res Ther. 2019 Jan 5;21(1):3. doi: 10.1186/s13075-018-1799-1.
500 Roles of 1,25(OH)2D3 and Vitamin D Receptor in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus by Regulating the Activation of CD4+ T Cells and the PKC/ERK Signaling Pathway.Cell Physiol Biochem. 2016;40(3-4):743-756. doi: 10.1159/000453135. Epub 2016 Dec 5.
501 CD74 is a T cell antigen in spondyloarthritis.Clin Exp Rheumatol. 2020 Mar-Apr;38(2):195-202. doi: 10.55563/clinexprheumatol/lezc69. Epub 2019 May 22.
502 Current treatment options for psoriatic arthritis: spotlight on abatacept.Ther Clin Risk Manag. 2018 Jun 6;14:1053-1059. doi: 10.2147/TCRM.S148586. eCollection 2018.
503 Selective inhibition of the p38 MAPK-MK2 axis inhibits inflammatory cues including inflammasome priming signals.J Exp Med. 2018 May 7;215(5):1315-1325. doi: 10.1084/jem.20172063. Epub 2018 Mar 16.
504 Pro-inflammatory effects of interleukin-35 in rheumatoid arthritis.Cytokine. 2015 May;73(1):36-43. doi: 10.1016/j.cyto.2015.01.019. Epub 2015 Feb 16.
505 Association of Increased F4/80(high) Macrophages With Suppression of Serum-Transfer Arthritis in Mice With Reduced FLIP in Myeloid Cells.Arthritis Rheumatol. 2017 Sep;69(9):1762-1771. doi: 10.1002/art.40151. Epub 2017 Aug 1.
506 Expression of the non-neuronal cholinergic system in human knee synovial tissue from patients with rheumatoid arthritis and osteoarthritis.Life Sci. 2012 Nov 27;91(21-22):1048-52. doi: 10.1016/j.lfs.2012.04.032. Epub 2012 May 1.
507 MiR-23a inhibited IL-17-mediated proinflammatory mediators expression via targeting IKK in articular chondrocytes.Int Immunopharmacol. 2017 Feb;43:1-6. doi: 10.1016/j.intimp.2016.11.031. Epub 2016 Dec 6.
508 Role of cannabinoid receptor 2 in mediating interleukin-1-induced inflammation in rheumatoid arthritis synovial fibroblasts.Clin Exp Rheumatol. 2019 Nov-Dec;37(6):1026-1035. Epub 2019 Mar 18.
509 Prevalence of HTLV-I Tax in a subset of patients with rheumatoid arthritis.Clin Exp Rheumatol. 2002 Mar-Apr;20(2):161-9.
510 Brief report: carboxypeptidase B serves as a protective mediator in osteoarthritis.Arthritis Rheumatol. 2014 Jan;66(1):101-106. doi: 10.1002/art.38213.
511 Leucocyte complement receptor 1 (CR1/CD35) transcript and its correlation with the clinical disease activity in rheumatoid arthritis patients.Clin Exp Immunol. 2014 Jun;176(3):327-35. doi: 10.1111/cei.12274.
512 Complement receptor type 1 (CR1, CD35) is a potent inhibitor of B-cell functions in rheumatoid arthritis patients.Int Immunol. 2013 Jan;25(1):25-33. doi: 10.1093/intimm/dxs090. Epub 2012 Sep 7.
513 Differential Effects of Inhibitor Combinations on Lysophosphatidic Acid-Mediated Chemokine Secretion in Unprimed and Tumor Necrosis Factor--Primed Synovial Fibroblasts.Front Pharmacol. 2017 Nov 21;8:848. doi: 10.3389/fphar.2017.00848. eCollection 2017.
514 Mapping the CRF-urocortins system in human osteoarthritic and rheumatoid synovial fibroblasts: effect of vasoactive intestinal peptide.J Cell Physiol. 2011 Dec;226(12):3261-9. doi: 10.1002/jcp.22687.
515 Monocyte/Macrophage Abnormalities Specific to Rheumatoid Arthritis Are Linked to miR-155 and Are Differentially Modulated by Different TNF Inhibitors.J Immunol. 2019 Oct 1;203(7):1766-1775. doi: 10.4049/jimmunol.1900386. Epub 2019 Sep 4.
516 Imatinib inhibits CSF1R that stimulates proliferation of rheumatoid arthritis fibroblast-like synoviocytes.Clin Exp Immunol. 2019 Feb;195(2):237-250. doi: 10.1111/cei.13220. Epub 2018 Oct 23.
517 The Secretome Derived From 3D-Cultured Umbilical Cord Tissue MSCs Counteracts Manifestations Typifying Rheumatoid Arthritis.Front Immunol. 2019 Feb 5;10:18. doi: 10.3389/fimmu.2019.00018. eCollection 2019.
518 Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis.J Immunol. 2016 Dec 1;197(11):4392-4402. doi: 10.4049/jimmunol.1600121. Epub 2016 Nov 2.
519 Protein tyrosine phosphatase non-receptor 22 and C-Src tyrosine kinase genes are down-regulated in patients with rheumatoid arthritis.Sci Rep. 2017 Sep 5;7(1):10525. doi: 10.1038/s41598-017-10915-9.
520 Inhibitory effect of Triperygium wilfordii polyglucoside on dipeptidyl peptidase I in vivo and in vitro.Biomed Pharmacother. 2017 Dec;96:466-470. doi: 10.1016/j.biopha.2017.09.139. Epub 2017 Oct 12.
521 Targeting cathepsin L (CL) by specific ribozymes decreases CL protein synthesis and cartilage destruction in rheumatoid arthritis.Gene Ther. 2004 Jul;11(13):1040-7. doi: 10.1038/sj.gt.3302265.
522 Comparison of cathepsins K and S expression within the rheumatoid and osteoarthritic synovium.Arthritis Rheum. 2002 Mar;46(3):663-74. doi: 10.1002/art.10114.
523 Tumor Necrosis Factor dynamically regulates the mRNA stabilome in rheumatoid arthritis fibroblast-like synoviocytes.PLoS One. 2017 Jul 14;12(7):e0179762. doi: 10.1371/journal.pone.0179762. eCollection 2017.
524 JN-2, a C-X-C motif chemokine receptor 3 antagonist, ameliorates arthritis progression in an animal model.Eur J Pharmacol. 2018 Mar 15;823:1-10. doi: 10.1016/j.ejphar.2018.01.037. Epub 2018 Feb 4.
525 CXCL9 and CXCL10 gene polymorphisms in patients with rheumatoid arthritis.Rheumatol Int. 2015 Aug;35(8):1319-23. doi: 10.1007/s00296-015-3234-0. Epub 2015 Feb 22.
526 Sinomenine inhibits osteolysis in breast cancer by reducing IL-8/CXCR1 and c-Fos/NFATc1 signaling.Pharmacol Res. 2019 Apr;142:140-150. doi: 10.1016/j.phrs.2019.02.015. Epub 2019 Feb 20.
527 Genetic variants within immune-modulating genes influence the risk of developing rheumatoid arthritis and anti-TNF drug response: a two-stage case-control study.Pharmacogenet Genomics. 2015 Sep;25(9):432-43. doi: 10.1097/FPC.0000000000000155.
528 CXCL16 upregulates RANKL expression in rheumatoid arthritis synovial fibroblasts through the JAK2/STAT3 and p38/MAPK signaling pathway.Inflamm Res. 2016 Mar;65(3):193-202. doi: 10.1007/s00011-015-0905-y. Epub 2015 Nov 30.
529 Gene expression profiling of rheumatoid arthritis synovial cells treated with antirheumatic drugs. J Biomol Screen. 2007 Apr;12(3):328-40. doi: 10.1177/1087057107299261. Epub 2007 Mar 22.
530 DDR2-CYR61-MMP1 Signaling Pathway Promotes Bone Erosion in Rheumatoid Arthritis Through Regulating Migration and Invasion of Fibroblast-Like Synoviocytes.J Bone Miner Res. 2017 Feb;32(2):407-418. doi: 10.1002/jbmr.2993. Epub 2016 Nov 3.
531 An in silico Workflow that Yields Experimentally Comparable Inhibitors for Human Dihydroorotate Dehydrogenase.Curr Comput Aided Drug Des. 2020;16(3):340-350. doi: 10.2174/1573409915666190528114703.
532 DICER1: A Key Player in Rheumatoid Arthritis, at the Crossroads of Cellular Stress, Innate Immunity, and Chronic Inflammation in Aging.Front Immunol. 2018 Jul 24;9:1647. doi: 10.3389/fimmu.2018.01647. eCollection 2018.
533 MiR-613 inhibits proliferation and invasion and induces apoptosis of rheumatoid arthritis synovial fibroblasts by direct down-regulation of DKK1.Cell Mol Biol Lett. 2019 Apr 19;24:8. doi: 10.1186/s11658-018-0130-0. eCollection 2019.
534 Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis.Pharmacogenomics J. 2013 Jun;13(3):235-41. doi: 10.1038/tpj.2012.8. Epub 2012 Apr 10.
535 Immunohistological localization of Notch receptors and their ligands Delta and Jagged in synovial tissues of rheumatoid arthritis.J Orthop Sci. 2005 Nov;10(6):589-94. doi: 10.1007/s00776-005-0943-3.
536 Zoledronic acid ameliorates the effects of secondary osteoporosis in rheumatoid arthritis patients.J Orthop Surg Res. 2019 Dec 10;14(1):421. doi: 10.1186/s13018-019-1492-3.
537 Influence of HumDN1 VNTR polymorphism on DNASE1 expression in systemic lupus erythematosus and rheumatoid arthritis.Immunol Invest. 2014;43(5):411-23. doi: 10.3109/08820139.2013.864666. Epub 2014 Feb 24.
538 Linguistic validation, validity and reliability of the British English versions of the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire and QuickDASH in people with rheumatoid arthritis.BMC Musculoskelet Disord. 2018 Apr 16;19(1):118. doi: 10.1186/s12891-018-2032-8.
539 Novel treatment of 99Tc-MDP improves clinical and radiographic results for patients with osteochondral lesions of the talus.Q J Nucl Med Mol Imaging. 2019 Jun;63(2):199-206. doi: 10.23736/S1824-4785.16.02872-7. Epub 2016 Jun 21.
540 A critical role of E2F transcription factor 2 in proinflammatory cytokines-dependent proliferation and invasiveness of fibroblast-like synoviocytes in rheumatoid Arthritis.Sci Rep. 2018 Feb 8;8(1):2623. doi: 10.1038/s41598-018-20782-7.
541 Novel role of Pin1 induction in type II collagen-mediated rheumatoid arthritis.J Immunol. 2009 Nov 15;183(10):6689-97. doi: 10.4049/jimmunol.0901431. Epub 2009 Oct 21.
542 HBA1C CONTROL AND COST-EFFECTIVENESS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS INITIATED ON CANAGLIFLOZIN OR A GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONIST IN A REAL-WORLD SETTING.Endocr Pract. 2018 Mar;24(3):273-287. doi: 10.4158/EP-2017-0066.
543 Effects of infliximab therapy on gene expression levels of tumor necrosis factor alpha, tristetraprolin, T cell intracellular antigen 1, and Hu antigen R in patients with rheumatoid arthritis.Arthritis Rheum. 2007 Jul;56(7):2160-9. doi: 10.1002/art.22724.
544 Neutrophil proteases degrade autoepitopes of NET-associated proteins.Clin Exp Immunol. 2020 Jan;199(1):1-8. doi: 10.1111/cei.13392. Epub 2019 Nov 15.
545 Understanding the Multifaceted Role of Ectonucleotide Pyrophosphatase/Phosphodiesterase 2 (ENPP2) and its Altered Behaviour in Human Diseases.Curr Mol Med. 2015;15(10):932-43. doi: 10.2174/1566524015666150921104804.
546 Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39.Ann Rheum Dis. 2019 Aug;78(8):1055-1061. doi: 10.1136/annrheumdis-2018-214877. Epub 2019 Apr 29.
547 Messenger-RNA expression of matrix metalloproteinases, tissue inhibitors of metalloproteinases, and transcription factors in rheumatic synovial cells under mechanical stimuli.Bone. 2001 Mar;28(3):303-9. doi: 10.1016/s8756-3282(00)00454-3.
548 Transcription Factor NFAT5 Promotes Migration and Invasion of Rheumatoid Synoviocytes via Coagulation Factor III and CCL2.J Immunol. 2018 Jul 15;201(2):359-370. doi: 10.4049/jimmunol.1701097. Epub 2018 May 23.
549 Abundant expression of the interleukin (IL)23 subunit p19, but low levels of bioactive IL23 in the rheumatoid synovium: differential expression and Toll-like receptor-(TLR) dependent regulation of the IL23 subunits, p19 and p40, in rheumatoid arthritis.Ann Rheum Dis. 2009 Jan;68(1):143-50. doi: 10.1136/ard.2007.082081. Epub 2008 Feb 14.
550 Neuronal FcRI mediates acute and chronic joint pain.J Clin Invest. 2019 Jun 18;129(9):3754-3769. doi: 10.1172/JCI128010.
551 Splice variants VEGF121 and VEGF165 of the angiogenic peptide vascular endothelial cell growth factor are expressed in the synovial tissue of patients with rheumatoid arthritis.J Rheumatol. 2001 Jul;28(7):1482-5.
552 Interleukin-35 inhibits angiogenesis through STAT1 signalling in rheumatoid synoviocytes.Clin Exp Rheumatol. 2018 Mar-Apr;36(2):223-227. Epub 2017 Aug 28.
553 FGF21 exerts comparable pharmacological efficacy with Adalimumab in ameliorating collagen-induced rheumatoid arthritis by regulating systematic inflammatory response.Biomed Pharmacother. 2017 May;89:751-760. doi: 10.1016/j.biopha.2017.02.059. Epub 2017 Mar 6.
554 Role of Zebrafish fhl1A in Satellite Cell and Skeletal Muscle Development.Curr Mol Med. 2017;17(9):627-636. doi: 10.2174/1566524018666180308113909.
555 IL-35 prevent bone loss through promotion of bone formation and angiogenesis in rheumatoid arthritis.Clin Exp Rheumatol. 2019 Sep-Oct;37(5):820-825. Epub 2019 Feb 11.
556 Citrullination of fibronectin alters integrin clustering and focal adhesion stability promoting stromal cell invasion.Matrix Biol. 2019 Sep;82:86-104. doi: 10.1016/j.matbio.2019.04.002. Epub 2019 Apr 17.
557 The folate receptor as a macrophage-mediated imaging and therapeutic target in rheumatoid arthritis.Drug Deliv Transl Res. 2019 Feb;9(1):366-378. doi: 10.1007/s13346-018-0589-2.
558 Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthritis.J Clin Invest. 2019 Apr 16;129(7):2669-2684. doi: 10.1172/JCI96832.
559 Foxc1 promotes the proliferation of fibroblast-like synoviocytes in rheumatoid arthritis via PI3K/AKT signalling pathway.Tissue Cell. 2018 Aug;53:15-22. doi: 10.1016/j.tice.2018.05.011. Epub 2018 May 22.
560 A novel antimicrobial peptide acting via formyl peptide receptor 2 shows therapeutic effects against rheumatoid arthritis.Sci Rep. 2018 Oct 2;8(1):14664. doi: 10.1038/s41598-018-32963-5.
561 Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis.Pharmacogenomics J. 2018 Sep;18(5):657-664. doi: 10.1038/s41397-018-0040-6. Epub 2018 Aug 31.
562 Increased expression of the proprotein convertase enzyme FURIN in rheumatoid arthritis.Scand J Rheumatol. 2019 May;48(3):173-177. doi: 10.1080/03009742.2018.1520294. Epub 2018 Nov 26.
563 Functional implications of disease-specific variants in loci jointly associated with coeliac disease and rheumatoid arthritis.Hum Mol Genet. 2016 Jan 1;25(1):180-90. doi: 10.1093/hmg/ddv455. Epub 2015 Nov 5.
564 Galectin 3 and its binding protein in rheumatoid arthritis.Arthritis Rheum. 2003 Oct;48(10):2788-95. doi: 10.1002/art.11287.
565 GADD45a and GADD45b Genes in Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients.J Clin Med. 2019 Jun 5;8(6):801. doi: 10.3390/jcm8060801.
566 Diminished soluble levels of growth arrest specific protein 6 and tyrosine kinase receptor Axl in patients with rheumatoid arthritis.Int J Rheum Dis. 2017 Jan;20(1):53-59. doi: 10.1111/1756-185X.12367. Epub 2014 Apr 7.
567 Germinal center kinase-like kinase overexpression in T cells as a novel biomarker in rheumatoid arthritis.Arthritis Rheum. 2013 Oct;65(10):2573-82. doi: 10.1002/art.38067.
568 Biomarkers associated with cardiovascular disease in patients with early rheumatoid arthritis.PLoS One. 2019 Aug 5;14(8):e0220531. doi: 10.1371/journal.pone.0220531. eCollection 2019.
569 Modulatory effects of inflammation and therapy on GDF-5 expression in rheumatoid arthritis synovium. Scand J Rheumatol. 2008 Nov-Dec;37(6):401-9. doi: 10.1080/03009740802120010.
570 Possible role of -galactosidase in rheumatoid arthritis.Mod Rheumatol. 2020 Jul;30(4):671-680. doi: 10.1080/14397595.2019.1640175. Epub 2019 Jul 22.
571 Activation of TGR5 alleviates inflammation in rheumatoid arthritis peripheral blood mononuclear cells and in mice with collagen IIinduced arthritis.Mol Med Rep. 2019 Nov;20(5):4540-4550. doi: 10.3892/mmr.2019.10711. Epub 2019 Sep 26.
572 Revisit of autoimmunity to glucose-6-phosphate isomerase in experimental and rheumatoid arthritis.Mod Rheumatol. 2020 Mar;30(2):232-238. doi: 10.1080/14397595.2019.1659539. Epub 2019 Sep 9.
573 Evaluating IBD-specific antiglycan antibodies in serum of patients with spondyloarthritis and rheumatoid arthritis: are they really specific?.Clin Exp Rheumatol. 2019 Jan-Feb;37(1):32-36. Epub 2018 Jun 25.
574 Regulation of GRB2 and FLICE2 expression by TNF-alpha in rheumatoid synovium.Immunol Lett. 2003 Dec 15;90(2-3):93-6. doi: 10.1016/j.imlet.2003.07.002.
575 Lysosomal -glucuronidase regulates Lyme and rheumatoid arthritis severity.J Clin Invest. 2014 Jan;124(1):311-20. doi: 10.1172/JCI72339. Epub 2013 Dec 16.
576 RETRACTED: GZMB gene silencing confers protection against synovial tissue hyperplasia and articular cartilage tissue injury in rheumatoid arthritis through the MAPK signaling pathway.Biomed Pharmacother. 2018 Jul;103:346-354. doi: 10.1016/j.biopha.2018.04.023. Epub 2018 Apr 24.
577 Etanercept improved anemia and decreased hepcidin gene expression in a rat model of rheumatoid arthritis.Biomed Pharmacother. 2019 Apr;112:108740. doi: 10.1016/j.biopha.2019.108740. Epub 2019 Mar 1.
578 Histone deacetylase 1 regulates tissue destruction in rheumatoid arthritis.Hum Mol Genet. 2015 Oct 1;24(19):5367-77. doi: 10.1093/hmg/ddv258. Epub 2015 Jul 7.
579 Reduced Activity of HDAC3 and Increased Acetylation of Histones H3 in Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis.J Immunol Res. 2018 Oct 3;2018:7313515. doi: 10.1155/2018/7313515. eCollection 2018.
580 Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.Am J Hum Genet. 2014 Apr 3;94(4):522-32. doi: 10.1016/j.ajhg.2014.02.013. Epub 2014 Mar 20.
581 MMP-2 silencing reduces the osteogenic transformation of fibroblasts by inhibiting the activation of the BMP/Smad pathway in ankylosing spondylitis.Oncol Lett. 2018 Mar;15(3):3281-3286. doi: 10.3892/ol.2017.7714. Epub 2017 Dec 29.
582 Clinical diagnostic significance of 14-3-3 protein, high-mobility group box-1, anti-cyclic citrullinated peptide antibodies, anti-mutated citrullinated vimentin antibodies and rheumatoid factor in rheumatoid arthritis.Br J Biomed Sci. 2020 Jan;77(1):19-23. doi: 10.1080/09674845.2019.1658425. Epub 2019 Sep 16.
583 The rheumatoid arthritis-associated autoantigen hnRNP-A2 (RA33) is a major stimulator of autoimmunity in rats with pristane-induced arthritis.J Immunol. 2007 Dec 1;179(11):7568-76. doi: 10.4049/jimmunol.179.11.7568.
584 Investigation of candidate gene copy number identifies FCGR3B as a potential biomarker for rheumatoid arthritis.Clin Exp Rheumatol. 2019 Nov-Dec;37(6):923-928. Epub 2019 Mar 7.
585 Overexpression of heparanase enhances T lymphocyte activities and intensifies the inflammatory response in a model of murine rheumatoid arthritis.Sci Rep. 2017 Apr 12;7:46229. doi: 10.1038/srep46229.
586 Histamine and Histamine H4 Receptor Promotes Osteoclastogenesis in Rheumatoid Arthritis.Sci Rep. 2017 Apr 26;7(1):1197. doi: 10.1038/s41598-017-01101-y.
587 11-hydroxysteroid dehydrogenase enzymes modulate effects of glucocorticoids in rheumatoid arthritis synovial cells.Neuroimmunomodulation. 2015;22(1-2):40-5. doi: 10.1159/000362725. Epub 2014 Sep 12.
588 The functional variant (Asp299gly) of toll-like receptor 4 (TLR4) influences TLR4-mediated cytokine production in rheumatoid arthritis.J Rheumatol. 2008 Apr;35(4):558-61. Epub 2008 Mar 15.
589 Biodistribution and pharmacokinetic profiles of an altered peptide ligand derived from heat-shock proteins 60 in Lewis rats.Cell Stress Chaperones. 2020 Jan;25(1):133-140. doi: 10.1007/s12192-019-01054-3. Epub 2019 Dec 4.
590 Genetic variation in the serotonin receptor gene affects immune responses in rheumatoid arthritis.Genes Immun. 2013 Mar;14(2):83-9. doi: 10.1038/gene.2012.56. Epub 2012 Dec 20.
591 Anti-rheumatoid arthritis effects in adjuvant-induced arthritis in rats and molecular docking studies of Polygonum orientale L. extracts.Immunol Lett. 2018 Sep;201:59-69. doi: 10.1016/j.imlet.2018.11.009. Epub 2018 Nov 22.
592 Production of the islet cell antigen ICA69 (p69) with baculovirus expression system: analysis with a solid-phase time-resolved fluorescence method of sera from patients with IDDM and rheumatoid arthritis.Autoimmunity. 1999;29(4):281-9. doi: 10.3109/08916939908994748.
593 ICOS Signaling Controls Induction and Maintenance of Collagen-Induced Arthritis.J Immunol. 2018 May 1;200(9):3067-3076. doi: 10.4049/jimmunol.1701305. Epub 2018 Mar 26.
594 Synovial Fibroblasts Selectively Suppress Th1 Cell Responses through IDO1-Mediated Tryptophan Catabolism.J Immunol. 2017 Apr 15;198(8):3109-3117. doi: 10.4049/jimmunol.1600600. Epub 2017 Mar 6.
595 Bone protection by inhibition of microRNA-182.Nat Commun. 2018 Oct 5;9(1):4108. doi: 10.1038/s41467-018-06446-0.
596 miR-143-3p regulates cell proliferation and apoptosis by targeting IGF1R and IGFBP5 and regulating the Ras/p38 MAPK signaling pathway in rheumatoid arthritis.Exp Ther Med. 2018 Apr;15(4):3781-3790. doi: 10.3892/etm.2018.5907. Epub 2018 Feb 28.
597 Insulin-Like Growth Factor Binding Protein 6 in Rheumatoid Arthritis: A Possible Novel Chemotactic Factor?.Front Immunol. 2017 May 18;8:554. doi: 10.3389/fimmu.2017.00554. eCollection 2017.
598 A mutation of cysteine 46 in IKK- promotes mPGES-1 and caveolin-1 expression to exacerbate osteoclast differentiation and osteolysis.Biochem Pharmacol. 2020 Feb;172:113762. doi: 10.1016/j.bcp.2019.113762. Epub 2019 Dec 14.
599 IL-29 enhances Toll-like receptor-mediated IL-6 and IL-8 production by the synovial fibroblasts from rheumatoid arthritis patients.Arthritis Res Ther. 2013 Oct 29;15(5):R170. doi: 10.1186/ar4357.
600 Decreased Gene Expression of Epstein-Barr Virus-Induced Gene 3 (EBI-3) may Contribute to the Pathogenesis of Rheumatoid Arthritis.Immunol Invest. 2019 May;48(4):367-377. doi: 10.1080/08820139.2018.1549066. Epub 2018 Dec 4.
601 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.Ann Rheum Dis. 2019 Mar;78(3):311-319. doi: 10.1136/annrheumdis-2018-214127. Epub 2018 Dec 20.
602 Anti-inflammatory and immune-regulatory cytokines in rheumatoid arthritis.Nat Rev Rheumatol. 2019 Jan;15(1):9-17. doi: 10.1038/s41584-018-0109-2.
603 Potential therapeutic effect of curcumin loaded hyalurosomes against inflammatory and oxidative processes involved in the pathogenesis of rheumatoid arthritis: The use of fibroblast-like synovial cells cultured in synovial fluid.Eur J Pharm Biopharm. 2019 Mar;136:84-92. doi: 10.1016/j.ejpb.2019.01.012. Epub 2019 Jan 17.
604 Beyond Autoantibodies: Biologic Roles of Human Autoreactive B Cells in Rheumatoid Arthritis Revealed by RNA-Sequencing.Arthritis Rheumatol. 2019 Apr;71(4):529-541. doi: 10.1002/art.40772. Epub 2019 Feb 23.
605 Transforming growth factor beta1 and laminin-111 cooperate in the induction of interleukin-16 expression in synovial fibroblasts from patients with rheumatoid arthritis.Ann Rheum Dis. 2010 Jan;69(1):270-5. doi: 10.1136/ard.2008.091116.
606 The IL-12 cytokine family in cardiovascular diseases.Cytokine. 2019 Oct;122:154188. doi: 10.1016/j.cyto.2017.10.010. Epub 2017 Oct 23.
607 The roles of IL-19 and IL-20 in the inflammation of degenerative lumbar spondylolisthesis.J Inflamm (Lond). 2018 Sep 18;15:19. doi: 10.1186/s12950-018-0195-6. eCollection 2018.
608 T-96 attenuates inflammation by inhibiting NF-B in adjuvant-induced arthritis.Front Biosci (Landmark Ed). 2020 Jan 1;25(3):498-512. doi: 10.2741/4816.
609 Arthritic and non-arthritic synovial fluids modulate IL10 and IL1RA gene expression in differentially activated primary human monocytes.Osteoarthritis Cartilage. 2015 Nov;23(11):1853-7. doi: 10.1016/j.joca.2015.06.003.
610 Berberine mitigates IL-21/IL-21R mediated autophagic influx in fibroblast-like synoviocytes and regulates Th17/Treg imbalance in rheumatoid arthritis.Apoptosis. 2019 Aug;24(7-8):644-661. doi: 10.1007/s10495-019-01548-6.
611 Evolving concepts of the pathogenesis of rheumatoid arthritis with focus on the early and late stages.Curr Opin Rheumatol. 2020 Jan;32(1):57-63. doi: 10.1097/BOR.0000000000000664.
612 Genetic variant in IL-32 is associated with the ex vivo cytokine production of anti-TNF treated PBMCs from rheumatoid arthritis patients.Sci Rep. 2018 Sep 19;8(1):14050. doi: 10.1038/s41598-018-32485-0.
613 Interleukin-33 serum levels in postmenopausal women with osteoporosis.Sci Rep. 2019 Mar 7;9(1):3786. doi: 10.1038/s41598-019-40212-6.
614 Elevated expression of interleukin-37 in patients with rheumatoid arthritis.Int J Rheum Dis. 2019 Jun;22(6):1123-1129. doi: 10.1111/1756-185X.13539. Epub 2019 Mar 6.
615 Increased Th17 cell frequency and poor clinical outcome in rheumatoid arthritis are associated with a genetic variant in the IL4R gene, rs1805010.Arthritis Rheumatol. 2014 May;66(5):1165-75. doi: 10.1002/art.38343.
616 Macrophages are the primary effector cells in IL-7-induced arthritis.Cell Mol Immunol. 2020 Jul;17(7):728-740. doi: 10.1038/s41423-019-0235-z. Epub 2019 Jun 13.
617 Identification of potential biomarkers for differential diagnosis between rheumatoid arthritis and osteoarthritis via integrative genomewide gene expression profiling analysis.Mol Med Rep. 2019 Jan;19(1):30-40. doi: 10.3892/mmr.2018.9677. Epub 2018 Nov 20.
618 MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis.Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11193-8. doi: 10.1073/pnas.1019536108. Epub 2011 Jun 20.
619 Confirmation of an IRAK3 polymorphism as a genetic marker predicting response to anti-TNF treatment in rheumatoid arthritis.Pharmacogenomics J. 2018 Jan;18(1):81-86. doi: 10.1038/tpj.2016.66. Epub 2016 Oct 4.
620 RGS1 silencing inhibits the inflammatory response and angiogenesis in rheumatoid arthritis rats through the inactivation of Toll-like receptor signaling pathway.J Cell Physiol. 2019 Nov;234(11):20432-20442. doi: 10.1002/jcp.28645. Epub 2019 Apr 22.
621 Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid arthritis.Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E12063-E12072. doi: 10.1073/pnas.1810553115. Epub 2018 Dec 3.
622 Screening of gene signatures for rheumatoid arthritis and osteoarthritis based on bioinformatics analysis.Mol Med Rep. 2016 Aug;14(2):1587-93. doi: 10.3892/mmr.2016.5423. Epub 2016 Jun 23.
623 Itch gene polymorphisms in healthy population and in patients affected by rheumatoid arthritis and atopic dermatitis.Cell Cycle. 2008 Nov 15;7(22):3607-9. doi: 10.4161/cc.7.22.6968. Epub 2008 Nov 9.
624 Integrin and transcriptomic profiles identify a distinctive synovial CD8+ T cell subpopulation in spondyloarthritis.Ann Rheum Dis. 2019 Nov;78(11):1566-1575. doi: 10.1136/annrheumdis-2019-215349. Epub 2019 Aug 30.
625 The association between the lymphocyte-monocyte ratio and disease activity in rheumatoid arthritis.Clin Rheumatol. 2017 Dec;36(12):2689-2695. doi: 10.1007/s10067-017-3815-2. Epub 2017 Sep 14.
626 Dendritic Cells from Rheumatoid Arthritis Patient Peripheral Blood Induce Th17 Cell Differentiation via miR-363/Integrin v/TGF- Axis.Scand J Immunol. 2017 Jun;85(6):441-449. doi: 10.1111/sji.12550.
627 Decreased RAGE expression in peripheral blood mononuclear cells of patients with rheumatoid arthritis.Clin Exp Rheumatol. 2009 May-Jun;27(3):483-90.
628 Preferential Inhibition of JAK1 Relative to JAK3 by Upadacitinib: Exposure-Response Analyses of Ex Vivo Data From 2 Phase 1 Clinical Trials and Comparison to Tofacitinib.J Clin Pharmacol. 2020 Feb;60(2):188-197. doi: 10.1002/jcph.1513. Epub 2019 Aug 25.
629 Safety profile of baricitinib in Japanese patients with active rheumatoid arthritis with over 1.6 years median time in treatment: An integrated analysis of Phases 2 and 3 trials.Mod Rheumatol. 2020 Jan;30(1):36-43. doi: 10.1080/14397595.2019.1583711. Epub 2019 Mar 21.
630 Astragalin Suppresses Inflammatory Responses and Bone Destruction in Mice With Collagen-Induced Arthritis and in Human Fibroblast-Like Synoviocytes.Front Pharmacol. 2019 Feb 12;10:94. doi: 10.3389/fphar.2019.00094. eCollection 2019.
631 Arsenic Trioxide in Synergy with Vitamin D Rescues the Defective VDR-PPAR- Functional Module of Autophagy in Rheumatoid Arthritis.PPAR Res. 2019 May 7;2019:6403504. doi: 10.1155/2019/6403504. eCollection 2019.
632 Identification of a 3'-Untranslated Genetic Variant of RARB Associated With Carotid Intima-Media Thickness in Rheumatoid Arthritis: A Genome-Wide Association Study.Arthritis Rheumatol. 2019 Mar;71(3):351-360. doi: 10.1002/art.40734. Epub 2019 Jan 18.
633 Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.Arthritis Rheumatol. 2014 Jan;66(1):24-30. doi: 10.1002/art.38196.
634 Association of Killer Cell Immunoglobulin- Like Receptor Genes in Iranian Patients with Rheumatoid Arthritis.PLoS One. 2015 Dec 11;10(12):e0143757. doi: 10.1371/journal.pone.0143757. eCollection 2015.
635 Association of KIR2DL2 gene with anti-cyclic citrullinated protein antibodies for serodiagnosis in rheumatoid arthritis.Medicina (B Aires). 2019;79(3):161-166.
636 Association study between KIR polymorphisms and rheumatoid arthritis disease: an updated meta-analysis.BMC Med Genet. 2019 Jan 29;20(1):24. doi: 10.1186/s12881-019-0754-6.
637 KIR2DL2 and KIR2DS2 as genetic markers to the methotrexate response in rheumatoid arthritis patients.Immunopharmacol Immunotoxicol. 2016 Aug;38(4):303-9. doi: 10.1080/08923973.2016.1194429.
638 Inhibition of hexokinases holds potential as treatment strategy for rheumatoid arthritis.Arthritis Res Ther. 2019 Apr 3;21(1):87. doi: 10.1186/s13075-019-1865-3.
639 Potential of sulfasalazine as a therapeutic sensitizer for CD44 splice variant 9-positive urogenital cancer.Med Oncol. 2016 May;33(5):45. doi: 10.1007/s12032-016-0760-x. Epub 2016 Apr 4.
640 Association of NKG2D gene variants with susceptibility and severity of rheumatoid arthritis.Clin Exp Immunol. 2017 Mar;187(3):369-375. doi: 10.1111/cei.12891. Epub 2016 Dec 18.
641 Association of MICA-129 polymorphism and circulating soluble MICA level with rheumatoid arthritis in a south Indian Tamil population.Int J Rheum Dis. 2018 Mar;21(3):656-663. doi: 10.1111/1756-185X.13138. Epub 2017 Jul 27.
642 LAIR-1 shedding from human fibroblast-like synoviocytes in rheumatoid arthritis following TNF- stimulation.Clin Exp Immunol. 2018 May;192(2):193-205. doi: 10.1111/cei.13100. Epub 2018 Feb 20.
643 IL-17A induces osteoblast differentiation by activating JAK2/STAT3 in ankylosing spondylitis.Arthritis Res Ther. 2018 Jun 7;20(1):115. doi: 10.1186/s13075-018-1582-3.
644 Physical Therapists' Ability to Distinguish Between Inflammatory and Noninflammatory Arthritis and to Appropriately Refer Patients to a Rheumatologist.Arthritis Care Res (Hoboken). 2020 Dec;72(12):1747-1754. doi: 10.1002/acr.24081. Epub 2020 Nov 6.
645 A sandwich enzyme immunoassay for the determination of neutrophil lipocalin in body fluids.Clin Chim Acta. 1995 Mar 31;235(2):137-45. doi: 10.1016/0009-8981(95)06020-7.
646 Influence of coronary artery disease and subclinical atherosclerosis related polymorphisms on the risk of atherosclerosis in rheumatoid arthritis.Sci Rep. 2017 Jan 6;7:40303. doi: 10.1038/srep40303.
647 Role and translational implication of galectins in arthritis pathophysiology and treatment: A systematic literature review.J Cell Physiol. 2019 Feb;234(2):1588-1605. doi: 10.1002/jcp.27026. Epub 2018 Aug 24.
648 Measurement of Neutral and Sialylated IgG N-Glycome at Asn-297 by CE-LIF to Assess Hypogalactosylation in Rheumatoid Arthritis.Methods Mol Biol. 2019;1972:77-93. doi: 10.1007/978-1-4939-9213-3_6.
649 Elevated expression of ciRS-7 in peripheral blood mononuclear cells from rheumatoid arthritis patients.Diagn Pathol. 2019 Feb 2;14(1):11. doi: 10.1186/s13000-019-0783-7.
650 IL-1 receptor antagonist protein production and gene expression in rheumatoid arthritis and osteoarthritis synovium.J Immunol. 1992 Aug 1;149(3):1054-62.
651 In-silico Studies of Isolated Phytoalkaloid Against Lipoxygenase: Study Based on Possible Correlation.Comb Chem High Throughput Screen. 2018;21(3):215-221. doi: 10.2174/1386207321666180220125406.
652 Serum lipoprotein(a) is not modified by interleukin-6 receptor antagonism or associated with inflammation in non-ST-elevation myocardial infarction.Int J Cardiol. 2019 Jan 1;274:348-350. doi: 10.1016/j.ijcard.2018.06.093. Epub 2018 Jun 27.
653 Berberine Modulates LPA Function to Inhibit the Proliferation and Inflammation of FLS-RA via p38/ERK MAPK Pathway Mediated by LPA(1).Evid Based Complement Alternat Med. 2019 Nov 3;2019:2580207. doi: 10.1155/2019/2580207. eCollection 2019.
654 Lysophosphatidic acid receptor 1 suppression sensitizes rheumatoid fibroblast-like synoviocytes to tumor necrosis factor-induced apoptosis.Arthritis Rheum. 2012 Aug;64(8):2460-70. doi: 10.1002/art.34443.
655 LRP5 gene polymorphisms and radiographic joint damage in rheumatoid arthritis patients.Osteoporos Int. 2018 Oct;29(10):2355-2368. doi: 10.1007/s00198-018-4625-3. Epub 2018 Jul 17.
656 Tertiary Lymphoid Structures in Rheumatoid Arthritis: NF-B-Inducing Kinase-Positive Endothelial Cells as Central Players.Am J Pathol. 2015 Jul;185(7):1935-43. doi: 10.1016/j.ajpath.2015.03.012. Epub 2015 May 9.
657 LTB(4) and BLT1 in inflammatory arthritis.Semin Immunol. 2017 Oct;33:52-57. doi: 10.1016/j.smim.2017.09.009.
658 Differential expression of leukotriene B4 receptor subtypes (BLT1 and BLT2) in human synovial tissues and synovial fluid leukocytes of patients with rheumatoid arthritis.J Rheumatol. 2003 Aug;30(8):1712-8.
659 LIGHT induces cell proliferation and inflammatory responses of rheumatoid arthritis synovial fibroblasts via lymphotoxin beta receptor.J Rheumatol. 2008 Jun;35(6):960-8. Epub 2008 Apr 15.
660 Deletion of Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1 in Mouse T Cells Protects Against Development of Autoimmune Arthritis but Leads to Spontaneous Osteoporosis.Arthritis Rheumatol. 2019 Dec;71(12):2005-2015. doi: 10.1002/art.41029. Epub 2019 Nov 9.
661 XBP1 activation enhances MANF expression via binding to endoplasmic reticulum stress response elements within MANF promoter region in hepatitis B.Int J Biochem Cell Biol. 2018 Jun;99:140-146. doi: 10.1016/j.biocel.2018.04.007. Epub 2018 Apr 9.
662 Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition.Sci Signal. 2018 Mar 6;11(520):eaal1601. doi: 10.1126/scisignal.aal1601.
663 Regulation of c-Jun N-terminal kinase by MEKK-2 and mitogen-activated protein kinase kinase kinases in rheumatoid arthritis.J Immunol. 2004 Feb 1;172(3):1612-8. doi: 10.4049/jimmunol.172.3.1612.
664 Regulation and function of apoptosis signal-regulating kinase 1 in rheumatoid arthritis.Biochem Pharmacol. 2018 May;151:282-290. doi: 10.1016/j.bcp.2018.01.041. Epub 2018 Feb 6.
665 IL-17A upregulates P-glycoprotein expression in peripheral blood lymphocytes of patients with rheumatoid arthritis through TAK1.Clin Exp Rheumatol. 2020 Mar-Apr;38(2):299-305. doi: 10.55563/clinexprheumatol/b23ohc. Epub 2019 Jul 19.
666 Protease-activated receptor 2, rather than protease-activated receptor 1, contributes to the aggressive properties of synovial fibroblasts in rheumatoid arthritis.Arthritis Rheum. 2012 Jan;64(1):88-98. doi: 10.1002/art.33323.
667 Diagnostic value of the serum Midkine in patients with rheumatoid arthritis.J Investig Med. 2020 Jan;68(1):37-44. doi: 10.1136/jim-2019-001097. Epub 2019 Jul 19.
668 Single nucleotide polymorphism of Methyl-CpG-binding protein 2 gene associates with juvenile idiopathic arthritis.Clin Rheumatol. 2018 Feb;37(2):375-381. doi: 10.1007/s10067-017-3968-z. Epub 2017 Dec 29.
669 Differential Expression of Renin-Angiotensin System-related Components in Patients with Rheumatoid Arthritis and Osteoarthritis.Am J Med Sci. 2020 Jan;359(1):17-26. doi: 10.1016/j.amjms.2019.10.014. Epub 2019 Nov 5.
670 Myelin oligodendrocyte basic protein and prognosis in behavioral-variant frontotemporal dementia.Neurology. 2014 Aug 5;83(6):502-9. doi: 10.1212/WNL.0000000000000668. Epub 2014 Jul 3.
671 Autoantibodies against myelin sheath and S100 are associated with cognitive dysfunction in patients with rheumatoid arthritis.Clin Rheumatol. 2017 Sep;36(9):1959-1968. doi: 10.1007/s10067-017-3724-4. Epub 2017 Jun 27.
672 Activated neutrophil carbamylates albumin via the release of myeloperoxidase and reactive oxygen species regardless of NETosis.Mod Rheumatol. 2020 Mar;30(2):345-349. doi: 10.1080/14397595.2019.1583819. Epub 2019 May 2.
673 Studying the effects of haplotype partitioning methods on the RA-associated genomic results from the North American Rheumatoid Arthritis Consortium (NARAC) dataset.J Adv Res. 2019 Jan 18;18:113-126. doi: 10.1016/j.jare.2019.01.006. eCollection 2019 Jul.
674 Myostatin induces tumor necrosis factor- expression in rheumatoid arthritis synovial fibroblasts through the PI3K-Akt signaling pathway.J Cell Physiol. 2019 Jun;234(6):9793-9801. doi: 10.1002/jcp.27665. Epub 2018 Oct 30.
675 Nonassociation of homocysteine gene polymorphisms with treatment outcome in South Indian Tamil Rheumatoid Arthritis patients.Clin Exp Med. 2018 Feb;18(1):101-107. doi: 10.1007/s10238-017-0469-y. Epub 2017 Aug 18.
676 Polymorphism and protein expression of MUTYH gene for risk of rheumatoid arthritis.BMC Musculoskelet Disord. 2017 Feb 7;18(1):69. doi: 10.1186/s12891-017-1437-0.
677 NAMPT Is an Essential Regulator of RA-Mediated Periodontal Inflammation.J Dent Res. 2017 Jun;96(6):703-711. doi: 10.1177/0022034517690389. Epub 2017 Feb 6.
678 CD38 and E2F transcription factor 2 have uniquely increased expression in rheumatoid arthritis synovial tissues.Clin Exp Immunol. 2014 May;176(2):222-31. doi: 10.1111/cei.12268.
679 IL-32 promoter SNP rs4786370 predisposes to modified lipoprotein profiles in patients with rheumatoid arthritis.Sci Rep. 2017 Jan 30;7:41629. doi: 10.1038/srep41629.
680 Role of NOD1 polymorphism in susceptibility and clinical progression of rheumatoid arthritis.Rheumatology (Oxford). 2013 May;52(5):806-14. doi: 10.1093/rheumatology/kes404. Epub 2013 Jan 25.
681 Notch-regulated miR-223 targets the aryl hydrocarbon receptor pathway and increases cytokine production in macrophages from rheumatoid arthritis patients.Sci Rep. 2016 Feb 3;6:20223. doi: 10.1038/srep20223.
682 Exome sequencing identifies novel rheumatoid arthritis-susceptible variants in the BTNL2.J Hum Genet. 2013 Apr;58(4):210-5. doi: 10.1038/jhg.2013.2. Epub 2013 Jan 31.
683 Physiology, pharmacology, and pathophysiology of neuropeptide S receptor.Prog Mol Biol Transl Sci. 2019;161:125-148. doi: 10.1016/bs.pmbts.2018.11.001. Epub 2019 Jan 29.
684 Methotrexate upregulates circadian transcriptional factors PAR bZIP to induce apoptosis on rheumatoid arthritis synovial fibroblasts.Arthritis Res Ther. 2018 Mar 22;20(1):55. doi: 10.1186/s13075-018-1552-9.
685 Tumor necrosis factor inhibition modulates thrombospondin-1 expression in human inflammatory joint disease through altered NR4A2 activity.Am J Pathol. 2013 Oct;183(4):1243-1257. doi: 10.1016/j.ajpath.2013.06.029. Epub 2013 Aug 6.
686 Association between Negatively Charged Low-Density Lipoprotein L5 and Subclinical Atherosclerosis in Rheumatoid Arthritis Patients.J Clin Med. 2019 Feb 3;8(2):177. doi: 10.3390/jcm8020177.
687 Resveratrol reduces store-operated Ca(2+) entry and enhances the apoptosis of fibroblast-like synoviocytes in adjuvant arthritis rats model via targeting ORAI1-STIM1 complex.Biol Res. 2019 Aug 19;52(1):45. doi: 10.1186/s40659-019-0250-7.
688 Osteoclast-Associated Receptor (OSCAR) Distribution in the Synovial Tissues of Patients with Active RA and TNF- and RANKL Regulation of Expression... Inflammation. 2017 Oct;40(5):1566-1575.
689 Osteopontin Promotes Oncostatin M Production in Human Osteoblasts: Implication of Rheumatoid Arthritis Therapy.J Immunol. 2015 Oct 1;195(7):3355-64. doi: 10.4049/jimmunol.1403191. Epub 2015 Aug 24.
690 Association of OSMR gene polymorphisms with rheumatoid arthritis and systemic lupus erythematosus patients.Autoimmunity. 2014 Feb;47(1):23-6. doi: 10.3109/08916934.2013.849701. Epub 2013 Nov 12.
691 Expression and function of the P2X(7) purinergic receptor in patients with systemic lupus erythematosus and rheumatoid arthritis.Hum Immunol. 2010 Aug;71(8):818-25. doi: 10.1016/j.humimm.2010.05.008. Epub 2010 May 20.
692 Epigenomic elements enriched in the promoters of autoimmunity susceptibility genes.Epigenetics. 2014 Feb;9(2):276-85. doi: 10.4161/epi.27021. Epub 2013 Nov 8.
693 Proprotein convertase subtilisin/kexin type 6 promotes invitro proliferation, migration and inflammatory cytokine secretion of synovial fibroblastlike cells from rheumatoid arthritis via nuclearB, signal transducer and activator of transcription 3 and extracellular signal regulated 1/2 pathways.Mol Med Rep. 2017 Dec;16(6):8477-8484. doi: 10.3892/mmr.2017.7595. Epub 2017 Sep 25.
694 Effect of IL-6 Receptor Blockade on Proprotein Convertase Subtilisin/Kexin Type-9 and Cholesterol Efflux Capacity in Rheumatoid Arthritis Patients.Horm Metab Res. 2019 Mar;51(3):200-209. doi: 10.1055/a-0833-4627. Epub 2019 Jan 29.
695 Ibudilast Inhibits Chemokine Expression in Rheumatoid Arthritis Synovial Fibroblasts and Exhibits Immunomodulatory Activity in Experimental Arthritis.Arthritis Rheumatol. 2019 May;71(5):703-711. doi: 10.1002/art.40787. Epub 2019 Apr 12.
696 Prealbumin, platelet factor 4 and S100A12 combination at baseline predicts good response to TNF alpha inhibitors in rheumatoid arthritis.Joint Bone Spine. 2019 Mar;86(2):195-201. doi: 10.1016/j.jbspin.2018.05.006. Epub 2018 Jun 6.
697 Inhibition of 6-phosphofructo-2-kinase suppresses fibroblast-like synoviocytes-mediated synovial inflammation and joint destruction in rheumatoid arthritis.Br J Pharmacol. 2017 May;174(9):893-908. doi: 10.1111/bph.13762. Epub 2017 Mar 27.
698 Placental growth factor-1 and -2 induce hyperplasia and invasiveness of primary rheumatoid synoviocytes.J Immunol. 2015 Mar 15;194(6):2513-21. doi: 10.4049/jimmunol.1402900. Epub 2015 Feb 18.
699 PBT-6, a Novel PI3KC2 Inhibitor in Rheumatoid Arthritis.Biomol Ther (Seoul). 2020 Mar 1;28(2):172-183. doi: 10.4062/biomolther.2019.153.
700 A bifunctional role for group IIA secreted phospholipase A2 in human rheumatoid fibroblast-like synoviocyte arachidonic acid metabolism.J Biol Chem. 2011 Jan 28;286(4):2492-503. doi: 10.1074/jbc.M110.123927. Epub 2010 Nov 10.
701 TLR4-dependent induction of vascular adhesion molecule-1 in rheumatoid arthritis synovial fibroblasts: Roles of cytosolic phospholipase A(2)alpha/cyclooxygenase-2.J Cell Physiol. 2010 May;223(2):480-91. doi: 10.1002/jcp.22059.
702 The Urokinase Plasminogen Activation System in Rheumatoid Arthritis: Pathophysiological Roles and Prospective Therapeutic Targets.Curr Drug Targets. 2019;20(9):970-981. doi: 10.2174/1389450120666181204164140.
703 Expression of CD147 (EMMPRIN) on neutrophils in rheumatoid arthritis enhances chemotaxis, matrix metalloproteinase production and invasiveness of synoviocytes.J Cell Mol Med. 2011 Apr;15(4):850-60. doi: 10.1111/j.1582-4934.2010.01084.x.
704 Cartilage oligomeric matrix protein forms protein complexes with synovial lubricin via non-covalent and covalent interactions.Osteoarthritis Cartilage. 2017 Sep;25(9):1496-1504. doi: 10.1016/j.joca.2017.03.016. Epub 2017 Apr 1.
705 Protein kinase C- upregulates sodium channel Nav1.9 in nociceptive dorsal root ganglion neurons in an inflammatory arthritis pain model of rat.J Cell Biochem. 2020 Jan;121(1):768-778. doi: 10.1002/jcb.29322. Epub 2019 Aug 5.
706 Protein kinase C-theta inhibitors: a novel therapy for inflammatory disorders.Curr Pharm Des. 2012;18(30):4725-46. doi: 10.2174/138161212802651625.
707 PKC-zeta expression is lower in osteoblasts from arthritic patients: IL1-beta and TNF-alpha induce a similar decrease in non-arthritic human osteoblasts.J Cell Biochem. 2008 Feb 1;103(2):547-55. doi: 10.1002/jcb.21424.
708 PRL -1149T allele (rs1341239) is associated with decreased risk of rheumatoid arthritis in population from southern Mexico: analysis of mRNA expression and PRL serum levels.Clin Rheumatol. 2019 Aug;38(8):2089-2097. doi: 10.1007/s10067-019-04517-1. Epub 2019 Mar 25.
709 Activated protein C targets immune cells and rheumatoid synovial fibroblasts to prevent inflammatory arthritis in mice.Rheumatology (Oxford). 2019 Oct 1;58(10):1850-1860. doi: 10.1093/rheumatology/key429.
710 Investigation of anti-DFS70 antibody in patients with systemic autoimmune rheumatic diseases.Clin Rheumatol. 2019 Dec;38(12):3627-3633. doi: 10.1007/s10067-019-04730-y. Epub 2019 Aug 8.
711 Suppressing mPGES-1 expression by sinomenine ameliorates inflammation and arthritis.Biochem Pharmacol. 2017 Oct 15;142:133-144. doi: 10.1016/j.bcp.2017.07.010. Epub 2017 Jul 13.
712 Circulating levels of free 25(OH)D increase at the onset of rheumatoid arthritis.PLoS One. 2019 Sep 26;14(9):e0219109. doi: 10.1371/journal.pone.0219109. eCollection 2019.
713 Elevated plasma midkine and pleiotrophin levels in patients with systemic lupus erythematosus.Oncotarget. 2017 Jun 20;8(25):40181-40189. doi: 10.18632/oncotarget.13658.
714 Regulation of Myelination by Exosome Associated Retinoic Acid Release from NG2-Positive Cells.J Neurosci. 2019 Apr 17;39(16):3013-3027. doi: 10.1523/JNEUROSCI.2922-18.2019. Epub 2019 Feb 13.
715 Expression and localisation of the new metalloproteinase inhibitor RECK (reversion inducing cysteine-rich protein with Kazal motifs) in inflamed synovial membranes of patients with rheumatoid arthritis.Ann Rheum Dis. 2005 Mar;64(3):368-74. doi: 10.1136/ard.2004.027870. Epub 2004 Oct 14.
716 Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions.Nat Commun. 2019 Sep 4;10(1):3975. doi: 10.1038/s41467-019-11606-x.
717 Retinoic Acid Receptor-Related Receptor Alpha Ameliorates Autoimmune Arthritis via Inhibiting of Th17 Cells and Osteoclastogenesis.Front Immunol. 2019 Oct 4;10:2270. doi: 10.3389/fimmu.2019.02270. eCollection 2019.
718 A novel function of artesunate on inhibiting migration and invasion of fibroblast-like synoviocytes from rheumatoid arthritis patients.Arthritis Res Ther. 2019 Jun 24;21(1):153. doi: 10.1186/s13075-019-1935-6.
719 Differential expression and regulation of the non-integrin 37/67-kDa laminin receptor on peripheral blood leukocytes of healthy individuals and patients with rheumatoid arthritis.Sci Rep. 2019 Feb 4;9(1):1149. doi: 10.1038/s41598-018-37907-7.
720 The Multifaceted S100A4 Protein in Cancer and Inflammation.Methods Mol Biol. 2019;1929:339-365. doi: 10.1007/978-1-4939-9030-6_22.
721 Targeted proteomics reveals serum amyloid A variants and alarmins S100A8-S100A9 as key plasma biomarkers of rheumatoid arthritis.Talanta. 2019 Nov 1;204:507-517. doi: 10.1016/j.talanta.2019.06.044. Epub 2019 Jun 11.
722 Host-Microbiome Synergistic Control on Sphingolipid Metabolism by Mechanotransduction in Model Arthritis.Biomolecules. 2019 Apr 9;9(4):144. doi: 10.3390/biom9040144.
723 Nurse-like cells in rheumatoid arthritis: Formation of survival niches cooperating between the cell types.Mod Rheumatol. 2019 May;29(3):401-405. doi: 10.1080/14397595.2018.1483305. Epub 2018 Jun 29.
724 Wnt signaling genes of murine chromosome 15 are involved in sex-affected pathways of inflammatory arthritis.Arthritis Rheum. 2012 Apr;64(4):1057-68. doi: 10.1002/art.33414. Epub 2011 Oct 17.
725 A novel splice variant of human L-selectin encodes a soluble molecule that is elevated in serum of patients with rheumatic diseases.Biochem Biophys Res Commun. 2015 Jul 10;462(4):371-7. doi: 10.1016/j.bbrc.2015.05.002. Epub 2015 May 14.
726 Decreased Expression of Semaphorin 3A and Semaphorin 7A Levels and Its Association with Systemic Lupus Erythematosus.Immunol Invest. 2020 Feb;49(1-2):69-80. doi: 10.1080/08820139.2019.1649280. Epub 2019 Aug 15.
727 Epigenetics and rheumatoid arthritis: the role of SENP1 in the regulation of MMP-1 expression.J Autoimmun. 2010 Aug;35(1):15-22. doi: 10.1016/j.jaut.2009.12.010. Epub 2010 Jan 15.
728 Thrombin in the synovial fluid of patients with rheumatoid arthritis mediates proliferation of synovial fibroblast-like cells by induction of platelet derived growth factor.J Rheumatol. 1996 Sep;23(9):1505-11.
729 Chemerin and PEDF Are Metaflammation-Related Biomarkers of Disease Activity and Obesity in Rheumatoid Arthritis.Front Med (Lausanne). 2018 Aug 3;5:207. doi: 10.3389/fmed.2018.00207. eCollection 2018.
730 Downregulation of rheumatoid arthritis-related antigen RA-A47 (HSP47/colligin-2) in chondrocytic cell lines induces apoptosis and cell-surface expression of RA-A47 in association with CD9.J Cell Physiol. 2005 Jan;202(1):191-204. doi: 10.1002/jcp.20112.
731 Real benefits of ultrasound evaluation of hand and foot synovitis for better characterisation of the disease activity in rheumatoid arthritis.Eur Radiol. 2019 Nov;29(11):6345-6354. doi: 10.1007/s00330-019-06187-8. Epub 2019 Apr 26.
732 Myeloid sirtuin 6 deficiency accelerates experimental rheumatoid arthritis by enhancing macrophage activation and infiltration into synovium.EBioMedicine. 2018 Dec;38:228-237. doi: 10.1016/j.ebiom.2018.11.005. Epub 2018 Nov 11.
733 Monocarboxylate transporter 4, associated with the acidification of synovial fluid, is a novel therapeutic target for inflammatory arthritis.Arthritis Rheumatol. 2015 Nov;67(11):2888-96. doi: 10.1002/art.39270.
734 Validation of the fibrosis-4 (FIB-4) index in the diagnosis of liver disease of rheumatoid arthritis patients treated with methotrexate.Mod Rheumatol. 2019 Nov;29(6):936-942. doi: 10.1080/14397595.2018.1542962. Epub 2019 Mar 21.
735 Membrane-Spanning Protein Genetic Polymorphisms Related to Methotrexate Therapeutic Outcomes in a Chinese Rheumatoid Arthritis Population.J Clin Pharmacol. 2019 Nov;59(11):1471-1476. doi: 10.1002/jcph.1446. Epub 2019 May 17.
736 Importance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts.Sci Rep. 2017 Apr 28;7(1):1258. doi: 10.1038/s41598-017-01438-4.
737 Key role of organic cation transporter 2 for the nephrotoxicity effect of triptolide in rheumatoid arthritis.Int Immunopharmacol. 2019 Dec;77:105959. doi: 10.1016/j.intimp.2019.105959. Epub 2019 Oct 20.
738 Increased expression of alpha 1-anti-trypsin in the synovial tissues of patients with ankylosing spondylitis.Clin Exp Rheumatol. 2012 Jan-Feb;30(1):39-44. Epub 2012 Mar 6.
739 Expression of choline and acetylcholine transporters in synovial tissue and cartilage of patients with rheumatoid arthritis and osteoarthritis.Cell Tissue Res. 2015 Feb;359(2):465-477. doi: 10.1007/s00441-014-2036-0. Epub 2014 Nov 25.
740 Role of SLC7A5 in Metabolic Reprogramming of Human Monocyte/Macrophage Immune Responses.Front Immunol. 2018 Jan 25;9:53. doi: 10.3389/fimmu.2018.00053. eCollection 2018.
741 Enhanced suppressor of cytokine signaling 3 in arthritic cartilage dysregulates human chondrocyte function.Arthritis Rheum. 2012 Oct;64(10):3313-23. doi: 10.1002/art.34529.
742 miR-212-3p reduced proliferation, and promoted apoptosis of fibroblast-like synoviocytes via down-regulating SOX5 in rheumatoid arthritis.Eur Rev Med Pharmacol Sci. 2018 Jan;22(2):461-471. doi: 10.26355/eurrev_201801_14196.
743 Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1.Autophagy. 2019 Mar;15(3):478-492. doi: 10.1080/15548627.2018.1522467. Epub 2018 Sep 22.
744 High mobility group box protein 1-A prognostic marker for structural joint damage in 10-year follow-up of patients with juvenile idiopathic arthritis.Semin Arthritis Rheum. 2017 Feb;46(4):444-450. doi: 10.1016/j.semarthrit.2016.08.017. Epub 2016 Aug 26.
745 DNA methylation and not allelic variation regulates STAT6 expression in human T cells.Clin Exp Med. 2010 Sep;10(3):143-52. doi: 10.1007/s10238-009-0083-8. Epub 2009 Dec 1.
746 Upregulation of HRD1 promotes cell migration and invasion in colon cancer.Mol Cell Biochem. 2019 Apr;454(1-2):1-9. doi: 10.1007/s11010-018-3447-0. Epub 2018 Oct 10.
747 Antagonism of NK-1R using aprepitant suppresses inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes.Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):1628-1634. doi: 10.1080/21691401.2019.1573177.
748 Regulation of neurokinin-1 receptor messenger RNA expression in synovial fibroblasts of patients with rheumatoid arthritis. Neuropeptides. 2005 Oct;39(5):467-74. doi: 10.1016/j.npep.2005.07.005. Epub 2005 Sep 9.
749 Effects of all-trans retinoic acid on the in vitro maturation of camel (Camelus dromedarius) cumulus-oocyte complexes.J Reprod Dev. 2019 Jun 14;65(3):215-221. doi: 10.1262/jrd.2018-073. Epub 2019 Feb 14.
750 Association of TAP2 gene polymorphisms in Chinese patients with rheumatoid arthritis.Clin Rheumatol. 2004 Feb;23(1):35-9. doi: 10.1007/s10067-003-0769-3. Epub 2003 Nov 18.
751 Genetics of rheumatoid arthritis contributes to biology and drug discovery.Nature. 2014 Feb 20;506(7488):376-81. doi: 10.1038/nature12873. Epub 2013 Dec 25.
752 Promotion of macrophage activation by Tie2 in the context of the inflamed synovia of rheumatoid arthritis and psoriatic arthritis patients.Rheumatology (Oxford). 2020 Feb 1;59(2):426-438. doi: 10.1093/rheumatology/kez315.
753 Causal graph-based analysis of genome-wide association data in rheumatoid arthritis.Biol Direct. 2011 May 18;6:25. doi: 10.1186/1745-6150-6-25.
754 Expression of Toll-like receptors and their signaling pathways in rheumatoid synovitis.J Rheumatol. 2011 May;38(5):810-20. doi: 10.3899/jrheum.100732. Epub 2011 Feb 15.
755 Evaluation of Toll-like-receptor gene family variants as prognostic biomarkers in rheumatoid arthritis.Immunol Lett. 2017 Jul;187:35-40. doi: 10.1016/j.imlet.2017.04.011. Epub 2017 May 7.
756 TLR3 Ligand Poly(I:C) Exerts Distinct Actions in Synovial Fibroblasts When Delivered by Extracellular Vesicles.Front Immunol. 2018 Jan 29;9:28. doi: 10.3389/fimmu.2018.00028. eCollection 2018.
757 MiR-3926 inhibits synovial fibroblasts proliferation and inflammatory cytokines secretion through targeting toll like receptor 5.Gene. 2019 Mar 1;687:200-206. doi: 10.1016/j.gene.2018.11.014. Epub 2018 Nov 6.
758 Mosaicism of XX and XXY cells accounts for high copy number of Toll like Receptor 7 and 8 genes in peripheral blood of men with Rheumatoid Arthritis.Sci Rep. 2019 Sep 9;9(1):12880. doi: 10.1038/s41598-019-49309-4.
759 Amelioration of collagen antibody induced arthritis in mice by an antibody directed against the fibronectin type III repeats of tenascin-C: Targeting fibronectin type III repeats of tenascin-C in rheumatoid arthritis.Int Immunopharmacol. 2018 May;58:15-23. doi: 10.1016/j.intimp.2018.02.022. Epub 2018 Mar 9.
760 Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes.Nat Genet. 2018 Oct;50(10):1366-1374. doi: 10.1038/s41588-018-0216-7. Epub 2018 Sep 17.
761 Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces rheumatoid arthritis synovial fibroblast proliferation through mitogen-activated protein kinases and phosphatidylinositol 3-kinase/Akt.J Biol Chem. 2005 Apr 22;280(16):15709-18. doi: 10.1074/jbc.M414469200. Epub 2005 Jan 31.
762 Inhibition of TNF-induced IL-6 by the TWEAK-Fn14 interaction in rheumatoid arthritis fibroblast like synoviocytes.Cell Immunol. 2012;272(2):293-8. doi: 10.1016/j.cellimm.2011.09.004. Epub 2011 Sep 22.
763 B cell activating factor (BAFF) and BAFF receptors: fakes and facts.Clin Exp Immunol. 2017 Dec;190(3):291-292. doi: 10.1111/cei.13039. Epub 2017 Sep 28.
764 Soluble Markers of Antibody Secreting Cell Function as Predictors of Infection Risk in Rheumatoid Arthritis.J Immunol Res. 2019 Apr 28;2019:3658215. doi: 10.1155/2019/3658215. eCollection 2019.
765 A variant of death-receptor 3 associated with rheumatoid arthritis interferes with apoptosis-induction of T cell.J Biol Chem. 2018 Feb 9;293(6):1933-1943. doi: 10.1074/jbc.M117.798884. Epub 2017 Nov 27.
766 Pathophysiological functions of CD30+ CD4+ T cells in rheumatoid arthritis.Acta Med Okayama. 2003 Dec;57(6):267-77. doi: 10.18926/AMO/32814.
767 The Study of Natural Compounds Targeting RANKL Signaling Pathway for the Treatment of Bone Diseases.Curr Drug Targets. 2020;21(4):344-357. doi: 10.2174/1389450120666190930145144.
768 A prioritization analysis of disease association by data-mining of functional annotation of human genes.Genomics. 2012 Jan;99(1):1-9. doi: 10.1016/j.ygeno.2011.10.002. Epub 2011 Oct 14.
769 The role of BAFF and APRIL in rheumatoid arthritis.J Cell Physiol. 2019 Aug;234(10):17050-17063. doi: 10.1002/jcp.28445. Epub 2019 Apr 2.
770 Gene polymorphisms and serum levels of TL1A in patients with rheumatoid arthritis.J Cell Physiol. 2019 Jul;234(7):11760-11767. doi: 10.1002/jcp.27834. Epub 2018 Nov 29.
771 Influence of the TNFSF4 rs1234315 polymorphism in the susceptibility to systemic lupus erythematosus and rheumatoid arthritis.Hum Immunol. 2019 Apr;80(4):270-275. doi: 10.1016/j.humimm.2018.11.006. Epub 2018 Nov 20.
772 Altered expression of TPP1 in fibroblast-like synovial cells might be involved in the pathogenesis of rheumatoid arthritis.Rheumatol Int. 2012 Aug;32(8):2503-10. doi: 10.1007/s00296-011-1992-x. Epub 2011 Jul 16.
773 Distinct expression of mast cell tryptase and protease activated receptor-2 in synovia of rheumatoid arthritis and osteoarthritis.Clin Rheumatol. 2007 Aug;26(8):1284-92. doi: 10.1007/s10067-006-0495-8. Epub 2007 Jan 5.
774 Thymic Stromal Lymphopoietin Isoforms, Inflammatory Disorders, and Cancer.Front Immunol. 2018 Jul 13;9:1595. doi: 10.3389/fimmu.2018.01595. eCollection 2018.
775 Autophagy promotes citrullination of VIM (vimentin) and its interaction with major histocompatibility complex class II in synovial fibroblasts.Autophagy. 2020 May;16(5):946-955. doi: 10.1080/15548627.2019.1664144. Epub 2019 Sep 8.
776 Thioredoxin 1 is associated with the proliferation and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes.Clin Rheumatol. 2018 Jan;37(1):117-125. doi: 10.1007/s10067-017-3832-1. Epub 2017 Sep 15.
777 A Network Pharmacology Approach to Explore Mechanism of Action of Longzuan Tongbi Formula on Rheumatoid Arthritis.Evid Based Complement Alternat Med. 2019 Jan 17;2019:5191362. doi: 10.1155/2019/5191362. eCollection 2019.
778 Inflammation and Lymphatic Function.Front Immunol. 2019 Feb 26;10:308. doi: 10.3389/fimmu.2019.00308. eCollection 2019.
779 Molecular Pathways: Evaluating the Potential for B7-H4 as an Immunoregulatory Target.Clin Cancer Res. 2017 Jun 15;23(12):2934-2941. doi: 10.1158/1078-0432.CCR-15-2440. Epub 2017 Mar 21.
780 Amelioration of Experimentally Induced Arthritis by Reducing Reactive Oxygen Species Production through the Intra-Articular Injection of Water-Soluble Fullerenol.Nanomaterials (Basel). 2019 Jun 23;9(6):909. doi: 10.3390/nano9060909.
781 Down-regulation of microRNA-142-3p inhibits the aggressive phenotypes of rheumatoid arthritis fibroblast-like synoviocytes through inhibiting nuclear factor-B signaling.Biosci Rep. 2019 Jul 8;39(7):BSR20190700. doi: 10.1042/BSR20190700. Print 2019 Jul 31.
782 Increased circulating Wnt5a protein in patients with rheumatoid arthritis-associated interstitial pneumonia (RA-ILD).Immunobiology. 2019 Jul;224(4):551-559. doi: 10.1016/j.imbio.2019.04.006. Epub 2019 Apr 30.
783 ZAP-70 Regulates Autoimmune Arthritis via Alterations in T Cell Activation and Apoptosis.Cells. 2019 May 24;8(5):504. doi: 10.3390/cells8050504.
784 Detecting novel micro RNAs in rheumatoid arthritis with gene-based association testing.Clin Exp Rheumatol. 2017 Jul-Aug;35(4):586-592. Epub 2017 Jan 27.
785 Potential role of platelets for atherosclerotic events in rheumatoid arthritis.FEBS Open Bio. 2018 Nov 6;8(12):1888-1896. doi: 10.1002/2211-5463.12531. eCollection 2018 Dec.
786 Comparison of fetuin-A and transforming growth factor beta 1 levels in patients with spondyloarthropathies and rheumatoid arthritis.Int J Rheum Dis. 2017 Dec;20(12):2020-2027. doi: 10.1111/1756-185X.12791. Epub 2016 Jan 22.
787 Th17 and IL-17 Cause Acceleration of Inflammation and Fat Loss by Inducing (2)-Glycoprotein 1 (AZGP1) in Rheumatoid Arthritis with High-Fat Diet.Am J Pathol. 2017 May;187(5):1049-1058. doi: 10.1016/j.ajpath.2016.12.023. Epub 2017 Mar 8.
788 Tie2 regulates endocardial sprouting and myocardial trabeculation.JCI Insight. 2019 May 21;5(13):e96002. doi: 10.1172/jci.insight.96002.
789 Evaluating the bromodomain protein BRD1 as a therapeutic target in rheumatoid arthritis.Sci Rep. 2018 Jul 24;8(1):11125. doi: 10.1038/s41598-018-29127-w.
790 CTLA-4Ig (abatacept) balances bone anabolic effects of T cells and Wnt-10b with antianabolic effects of osteoblastic sclerostin.Ann N Y Acad Sci. 2018 Mar;1415(1):21-33. doi: 10.1111/nyas.13643. Epub 2018 Mar 3.
791 CDK7 inhibition suppresses rheumatoid arthritis inflammation via blockage of NF-B activation and IL-1/IL-6 secretion.J Cell Mol Med. 2018 Feb;22(2):1292-1301. doi: 10.1111/jcmm.13414. Epub 2017 Oct 30.
792 Fibroblast-like synoviocyte migration is enhanced by IL-17-mediated overexpression of L-type amino acid transporter 1 (LAT1) via the mTOR/4E-BP1 pathway.Amino Acids. 2018 Feb;50(2):331-340. doi: 10.1007/s00726-017-2520-4. Epub 2017 Dec 2.
793 Expression and localization analyses of the cholinergic anti-inflammatory pathway and 7nAchR in different tissues of rats with rheumatoid arthritis.Acta Histochem. 2019 Aug;121(6):742-749. doi: 10.1016/j.acthis.2019.07.001. Epub 2019 Jul 3.
794 The association between insulin-like growth factor 1 (IGF-1), IGF-binding proteins (IGFBPs), and the carboxyterminal propeptide of type I procollagen (PICP) in pre- and postmenopausal women with rheumatoid arthritis.Scand J Rheumatol. 2017 May;46(3):171-179. doi: 10.1080/03009742.2016.1203020. Epub 2016 Oct 24.
795 Serum Cesium, Rhenium, and Rubidium in Rheumatoid Arthritis Patients.Biol Trace Elem Res. 2019 Jun;189(2):379-386. doi: 10.1007/s12011-018-1497-5. Epub 2018 Aug 31.
796 Assessment of hemostatic disturbances in women with established rheumatoid arthritis.Clin Rheumatol. 2019 Nov;38(11):3005-3014. doi: 10.1007/s10067-019-04629-8. Epub 2019 Jun 17.
797 Increased DOT1L in synovial biopsies of patients with OA and RA.Clin Rheumatol. 2018 May;37(5):1327-1332. doi: 10.1007/s10067-017-3941-x. Epub 2017 Dec 13.
798 Thrombin inhibits the anti-myeloperoxidase and ferroxidase functions of ceruloplasmin: relevance in rheumatoid arthritis. Free Radic Biol Med. 2015 Sep;86:279-94.
799 Rheumatic Disease: Protease-Activated Receptor-2 in Synovial Joint Pathobiology.Front Endocrinol (Lausanne). 2018 May 23;9:257. doi: 10.3389/fendo.2018.00257. eCollection 2018.
800 Uncovering Cellular retinoic acid-binding protein 2 as a potential target for rheumatoid arthritis synovial hyperplasia.Sci Rep. 2018 Jun 7;8(1):8731. doi: 10.1038/s41598-018-26027-x.
801 BMP9 inhibits the proliferation and migration of fibroblast-like synoviocytes in rheumatoid arthritis via the PI3K/AKT signaling pathway.Int Immunopharmacol. 2019 Sep;74:105685. doi: 10.1016/j.intimp.2019.105685. Epub 2019 Jun 13.
802 Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models.Front Immunol. 2018 Apr 13;9:742. doi: 10.3389/fimmu.2018.00742. eCollection 2018.
803 The protective effects of the GPR39 agonist TC-G 1008 against TNF--induced inflammation in human fibroblast-like synoviocytes (FLSs).Eur J Pharmacol. 2019 Dec 15;865:172663. doi: 10.1016/j.ejphar.2019.172663. Epub 2019 Sep 17.
804 mGlu1 tonically regulates levels of calcium-permeable AMPA receptors in cultured nucleus accumbens neurons through retinoic acid signaling and protein translation.Eur J Neurosci. 2019 Aug;50(3):2590-2601. doi: 10.1111/ejn.14151. Epub 2018 Oct 14.
805 Anti-inflammatory Effects of a Small Molecule Gastrin-Releasing Peptide Receptor Antagonist on Adjuvant-Induced Rheumatoid Arthritis in Rats.Chem Pharm Bull (Tokyo). 2018 Apr 1;66(4):410-415. doi: 10.1248/cpb.c17-00887. Epub 2018 Feb 8.
806 Orexin A may suppress inflammatory response in fibroblast-like synoviocytes.Biomed Pharmacother. 2018 Nov;107:763-768. doi: 10.1016/j.biopha.2018.07.159. Epub 2018 Aug 21.
807 Amylin in the insulin resistance of patients with rheumatoid arthritis.Clin Exp Rheumatol. 2018 May-Jun;36(3):421-427. Epub 2018 Jan 15.
808 Therapeutic antibody targeting of indoleamine-2,3-dioxygenase (IDO2) inhibits autoimmune arthritis.Clin Immunol. 2017 Jun;179:8-16. doi: 10.1016/j.clim.2017.01.016. Epub 2017 Feb 20.
809 Analysis of Helios gene expression and Foxp3 TSDR methylation in the newly diagnosed Rheumatoid Arthritis patients.Immunol Invest. 2018 Aug;47(6):632-642. doi: 10.1080/08820139.2018.1480029. Epub 2018 May 31.
810 Pharmacodynamic biomarkers and differential effects of TNF- and GM-CSF-targeting biologics in rheumatoid arthritis.Int J Rheum Dis. 2019 Apr;22(4):646-653. doi: 10.1111/1756-185X.13395. Epub 2018 Oct 24.
811 Systematic Analysis of Differential Expression Profile in Rheumatoid Arthritis Chondrocytes Using Next-Generation Sequencing and Bioinformatics Approaches.Int J Med Sci. 2018 Jul 13;15(11):1129-1142. doi: 10.7150/ijms.27056. eCollection 2018.
812 Synovial tissue quantitative proteomics analysis reveals paeoniflorin decreases LIFR and ASPN proteins in experimental rheumatoid arthritis.Drug Des Devel Ther. 2018 Mar 6;12:463-473. doi: 10.2147/DDDT.S153927. eCollection 2018.
813 PIM-1 kinase is a novel regulator of proinflammatory cytokine-mediated responses in rheumatoid arthritis fibroblast-like synoviocytes.Rheumatology (Oxford). 2019 Jan 1;58(1):154-164. doi: 10.1093/rheumatology/key261.
814 Evaluation of the therapeutic potential of the selective p38 MAPK inhibitor Skepinone-L and the dual p38/JNK 3 inhibitor LN 950 in experimental K/BxN serum transfer arthritis.Inflammopharmacology. 2019 Dec;27(6):1217-1227. doi: 10.1007/s10787-019-00593-6. Epub 2019 Apr 29.
815 Myelin basic protein as a novel genetic risk factor in rheumatoid arthritis--a genome-wide study combined with immunological analyses.PLoS One. 2011;6(6):e20457. doi: 10.1371/journal.pone.0020457. Epub 2011 Jun 3.
816 Retinoid interferon-induced mortality19 (GRIM19) inhibits proliferation and invasion in rheumatoid arthritis fibroblast-like synoviocytes.Biomed Pharmacother. 2018 Feb;98:719-725. doi: 10.1016/j.biopha.2017.12.114. Epub 2018 Jan 4.
817 Methotrexate Restores CD73 Expression on Th1.17 in Rheumatoid Arthritis and Psoriatic Arthritis Patients and May Contribute to Its Anti-Inflammatory Effect through Ado Production.J Clin Med. 2019 Nov 3;8(11):1859. doi: 10.3390/jcm8111859.
818 P2Y11 receptor antagonist NF340 ameliorates inflammation in human fibroblast-like synoviocytes: An implication in rheumatoid arthritis.IUBMB Life. 2019 Oct;71(10):1552-1560. doi: 10.1002/iub.2077. Epub 2019 Jul 13.
819 Effects of ticagrelor, empagliflozin and tamoxifen against experimentally-induced vascular reactivity defects in rats in vivo and in vitro.Pharmacol Rep. 2019 Dec;71(6):1034-1043. doi: 10.1016/j.pharep.2019.06.004. Epub 2019 Jun 6.
820 miR-125 regulates PI3K/Akt/mTOR signaling pathway in rheumatoid arthritis rats via PARP2.Biosci Rep. 2019 Jan 8;39(1):BSR20180890. doi: 10.1042/BSR20180890. Print 2019 Jan 31.
821 PhosphoLipid transfer protein (PLTP) exerts a direct pro-inflammatory effect on rheumatoid arthritis (RA) fibroblasts-like-synoviocytes (FLS) independently of its lipid transfer activity.PLoS One. 2018 Mar 22;13(3):e0193815. doi: 10.1371/journal.pone.0193815. eCollection 2018.
822 Progressive multifocal leukoencephalopathy in rituximab-treated rheumatic diseases: a rare event.J Neurovirol. 2018 Jun;24(3):323-331. doi: 10.1007/s13365-018-0615-7. Epub 2018 Mar 5.
823 Inhibition of protein phosphatase PPM1D enhances retinoic acid-induced differentiation in human embryonic carcinoma cell line.J Biochem. 2019 Jun 1;165(6):471-477. doi: 10.1093/jb/mvy119.
824 Role of protein arginine methyltransferase 5 in inflammation and migration of fibroblast-like synoviocytes in rheumatoid arthritis.J Cell Mol Med. 2017 Apr;21(4):781-790. doi: 10.1111/jcmm.13020. Epub 2016 Nov 17.
825 Osteogenic differentiation of fibroblast-like synovial cells in rheumatoid arthritis is induced by microRNA-218 through a ROBO/Slit pathway.Arthritis Res Ther. 2018 Aug 29;20(1):189. doi: 10.1186/s13075-018-1703-z.
826 An enhanced RRM2 siRNA delivery to rheumatoid arthritis fibroblast-like synoviocytes through a liposomeprotamine-DNA-siRNA complex with cell permeable peptides.Int J Mol Med. 2018 Nov;42(5):2393-2402. doi: 10.3892/ijmm.2018.3815. Epub 2018 Aug 8.
827 How kinematic disturbance in the deformed rheumatoid thumb impacts on hand function: a biomechanical and functional perspective.Disabil Rehabil. 2017 Feb;39(4):338-345. doi: 10.3109/09638288.2016.1141244. Epub 2016 Feb 17.
828 CD147-mediated chemotaxis of CD4(+)CD161(+) T cells may contribute to local inflammation in rheumatoid arthritis.Clin Rheumatol. 2018 Jan;37(1):59-66. doi: 10.1007/s10067-017-3800-9. Epub 2017 Sep 25.
829 miR-26a-5p Regulates Synovial Fibroblast Invasion in Patients with Rheumatoid Arthritis by Targeting Smad 1.Med Sci Monit. 2018 Jul 26;24:5178-5184. doi: 10.12659/MSM.907816.
830 High-sensitivity cardiac troponin I is a biomarker for occult coronary plaque burden and cardiovascular events in patients with rheumatoid arthritis.Rheumatology (Oxford). 2018 Jun 1;57(6):1080-1088. doi: 10.1093/rheumatology/key057.
831 A TRAF6 genetic variant is associated with low bone mineral density in rheumatoid arthritis.Clin Rheumatol. 2019 Apr;38(4):1067-1074. doi: 10.1007/s10067-018-4362-1. Epub 2018 Dec 1.
832 Modulator role of infliximab and methotrexate through the transient receptor potential melastatin 2 (TRPM2) channel in neutrophils of patients with rheumatoid arthritis: a pilot study.Arch Med Sci. 2019 Oct;15(6):1415-1424. doi: 10.5114/aoms.2018.79485. Epub 2018 Nov 19.
833 Tyro3/Axl/Mertk-deficient mice develop bone marrow edema which is an early pathological marker in rheumatoid arthritis.PLoS One. 2018 Oct 18;13(10):e0205902. doi: 10.1371/journal.pone.0205902. eCollection 2018.
834 The 3'-UTR (CA)n microsatellite on CD40LG gene as a possible genetic marker for rheumatoid arthritis in Mexican population: impact on CD40LG mRNA expression.Clin Rheumatol. 2018 Feb;37(2):345-353. doi: 10.1007/s10067-017-3853-9. Epub 2017 Sep 30.
835 Central role of RIPK1-VDAC1 pathway on cardiac impairment in a non-human primate model of rheumatoid arthritis.J Mol Cell Cardiol. 2018 Dec;125:50-60. doi: 10.1016/j.yjmcc.2018.10.015. Epub 2018 Oct 17.
836 A genome-wide association study identifies SLC8A3 as a susceptibility locus for ACPA-positive rheumatoid arthritis.Rheumatology (Oxford). 2016 Jun;55(6):1106-11. doi: 10.1093/rheumatology/kew035. Epub 2016 Mar 15.
837 Influence of genetic copy number variants of the human GLUT3 glucose transporter gene SLC2A3 on protein expression, glycolysis and rheumatoid arthritis risk: A genetic replication study.Mol Genet Metab Rep. 2019 Apr 6;19:100470. doi: 10.1016/j.ymgmr.2019.100470. eCollection 2019 Jun.
838 Coexistent rheumatoid arthritis and gout: a case series and review of the literature.Clin Rheumatol. 2017 Dec;36(12):2835-2838. doi: 10.1007/s10067-017-3856-6. Epub 2017 Oct 12.
839 A genetic association study of carotid intima-media thickness (CIMT) and plaque in Mexican Americans and European Americans with rheumatoid arthritis.Atherosclerosis. 2018 Apr;271:92-101. doi: 10.1016/j.atherosclerosis.2017.11.024. Epub 2017 Nov 26.
840 Pharmacological and pathophysiological roles of carnitine/organic cation transporters (OCTNs: SLC22A4, SLC22A5 and Slc22a21).Biopharm Drug Dispos. 2013 Jan;34(1):29-44. doi: 10.1002/bdd.1816. Epub 2012 Oct 14.
841 PAR(2) expression in peripheral blood monocytes of patients with rheumatoid arthritis.Ann Rheum Dis. 2012 Jun;71(6):1049-54. doi: 10.1136/annrheumdis-2011-200703. Epub 2012 Jan 30.
842 BAT1 promoter polymorphism is associated with rheumatoid arthritis susceptibility.J Rheumatol. 2008 May;35(5):741-4. Epub 2008 Mar 15.
843 1,4-Galactosyltransferase-I contributes to the inflammatory processes in synovial tissue of patients with rheumatoid arthritis.Inflamm Res. 2010 Dec;59(12):1009-18. doi: 10.1007/s00011-010-0217-1. Epub 2010 May 20.
844 CYB5A polymorphism increases androgens and reduces risk of rheumatoid arthritis in women.Arthritis Res Ther. 2015 Mar 11;17(1):56. doi: 10.1186/s13075-015-0574-9.
845 Enrichment of vitamin D response elements in RA-associated loci supports a role for vitamin D in the pathogenesis of RA.Genes Immun. 2013 Jul-Aug;14(5):325-9. doi: 10.1038/gene.2013.23. Epub 2013 May 2.
846 CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines.Arthritis Rheum. 2005 Mar;52(3):770-8. doi: 10.1002/art.20950.
847 Association of tri-nucleotide (CAG and GGC) repeat polymorphism of androgen receptor gene in Taiwanese women with refractory or remission rheumatoid arthritis.Clin Rheumatol. 2007 Dec;26(12):2051. doi: 10.1007/s10067-007-0616-z. Epub 2007 Apr 13.
848 Genes associated with rheumatoid arthritis and mild inflammatory arthritis. I. Major histocompatibility complex class I, II, and III allotypes.Ann Rheum Dis. 1990 Apr;49(4):219-24. doi: 10.1136/ard.49.4.219.
849 HPRT- mutant T cells in the peripheral blood and synovial tissue of patients with rheumatoid arthritis.Arthritis Rheum. 1998 Oct;41(10):1772-82. doi: 10.1002/1529-0131(199810)41:10<1772::AID-ART9>3.0.CO;2-C.
850 Risk of progression from undifferentiated arthritis to rheumatoid arthritis: the effect of the PTPN22 1858T-allele in anti-citrullinated peptide antibody positive patients.Rheumatology (Oxford). 2007 Jul;46(7):1092-5. doi: 10.1093/rheumatology/kem006. Epub 2007 Mar 6.
851 The interferon regulatory factor 5 gene confers susceptibility to rheumatoid arthritis and influences its erosive phenotype.Ann Rheum Dis. 2011 Jan;70(1):117-21. doi: 10.1136/ard.2010.129171. Epub 2010 Oct 26.
852 Tocilizumab-induced hyperbilirubinemia in Japanese patients with rheumatoid arthritis: its association with UDP glucuronosyltransferase 1A1 gene polymorphisms.Mod Rheumatol. 2012 Aug;22(4):515-23. doi: 10.1007/s10165-011-0537-1. Epub 2011 Oct 13.
853 Survival of lymphocytes is not restricted by IDO-expressing fibroblast from rheumatoid arthritis patients.Immunopharmacol Immunotoxicol. 2019 Apr;41(2):214-223. doi: 10.1080/08923973.2019.1569048. Epub 2019 Feb 4.
854 Clinical and genetic characteristics of upper gastrointestinal disease in rheumatoid arthritis.J Rheumatol. 1987 Aug;14(4):692-9.
855 Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio.PLoS One. 2017 Aug 8;12(8):e0182904. doi: 10.1371/journal.pone.0182904. eCollection 2017.
856 Vitamin D Receptor Polymorphism and DHCR7 Contribute to the Abnormal Interplay Between Vitamin D and Lipid Profile in Rheumatoid Arthritis.Sci Rep. 2019 Feb 22;9(1):2546. doi: 10.1038/s41598-019-38756-8.
857 Glutaminase 1 plays a key role in the cell growth of fibroblast-like synoviocytes in rheumatoid arthritis.Arthritis Res Ther. 2017 Apr 11;19(1):76. doi: 10.1186/s13075-017-1283-3.
858 Methotrexate treatment in rheumatoid arthritis and elevated liver enzymes: A long-term follow-up of predictors, surveillance, and outcome in clinical practice.Int J Rheum Dis. 2019 Jul;22(7):1226-1232. doi: 10.1111/1756-185X.13576. Epub 2019 Apr 22.
859 MSRA polymorphism is associated with the risk of rheumatoid arthritis in a Chinese population.Scand J Rheumatol. 2013;42(2):91-6. doi: 10.3109/03009742.2012.730626. Epub 2012 Dec 18.
860 Impact of interactions of cigarette smoking with NAT2 polymorphisms on rheumatoid arthritis risk in African Americans.Arthritis Rheum. 2012 Mar;64(3):655-64. doi: 10.1002/art.33408.
861 Red cell enzyme types in rheumatic diseases.Hum Hered. 1985;35(2):107-10. doi: 10.1159/000153525.
862 Differential expression of vitamin D associated genes in the aorta of coronary artery disease patients with and without rheumatoid arthritis.PLoS One. 2018 Aug 23;13(8):e0202346. doi: 10.1371/journal.pone.0202346. eCollection 2018.
863 Inhibition of spermidine/spermine N1-acetyltransferase activity: a new therapeutic concept in rheumatoid arthritis.Arthritis Rheumatol. 2014 Jul;66(7):1723-33. doi: 10.1002/art.38574.
864 Rheumatoid arthritis and schizophrenia: a negative association at a dimensional level.Schizophr Res. 2004 Jan 1;66(1):21-9. doi: 10.1016/s0920-9964(03)00017-3.
865 Sepiapterin Reductase Inhibition Leading to Selective Reduction of Inflammatory Joint Pain in Mice and Increased Urinary Sepiapterin Levels in Humans and Mice.Arthritis Rheumatol. 2020 Jan;72(1):57-66. doi: 10.1002/art.41060. Epub 2019 Nov 28.
866 Modification of Sexual Hormones in Rheumatoid Arthritis Patients by M2000 (-D-mannuronic Acid) as a Novel NSAID with Immunosuppressive Property.Endocr Metab Immune Disord Drug Targets. 2018;18(5):530-536. doi: 10.2174/1871530318666180418111354.
867 High frequency of mutant thiopurine S-methyltransferase genotypes in Mexican patients with systemic lupus erythematosus and rheumatoid arthritis.Clin Rheumatol. 2018 Apr;37(4):963-970. doi: 10.1007/s10067-017-3955-4. Epub 2017 Dec 20.
868 IL-12B Gene Polymorphisms and IL-12 p70 Serum Levels Among Patients with Rheumatoid Arthritis.Scand J Immunol. 2017 Feb;85(2):147-154. doi: 10.1111/sji.12514.
869 Circulating Biomarkers for Predicting Infliximab Response in Rheumatoid Arthritis: A Systematic Bioinformatics Analysis.Med Sci Monit. 2017 Apr 17;23:1849-1855. doi: 10.12659/msm.900897.
870 Aberrant expression of aldehyde dehydrogenase 1A (ALDH1A) subfamily genes in acute lymphoblastic leukaemia is a common feature of T-lineage tumours.Br J Haematol. 2015 Jan;168(2):246-57. doi: 10.1111/bjh.13120. Epub 2014 Sep 11.
871 Direct activation of chordoblasts by retinoic acid is required for segmented centra mineralization during zebrafish spine development.Development. 2018 May 8;145(9):dev159418. doi: 10.1242/dev.159418.
872 Metabolomic profiles of induced pluripotent stem cells derived from patients with rheumatoid arthritis and osteoarthritis.Stem Cell Res Ther. 2019 Nov 15;10(1):319. doi: 10.1186/s13287-019-1408-5.
873 Smoothened Regulates Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via Activation of Rho GTPase Signaling.Front Immunol. 2017 Feb 15;8:159. doi: 10.3389/fimmu.2017.00159. eCollection 2017.
874 Superinduction of interleukin 8 mRNA in activated monocyte derived macrophages from rheumatoid arthritis patients.Ann Rheum Dis. 1999 Oct;58(10):648-52. doi: 10.1136/ard.58.10.648.
875 AAA-ATPase p97 suppresses apoptotic and autophagy-associated cell death in rheumatoid arthritis synovial fibroblasts.Oncotarget. 2016 Sep 27;7(39):64221-64232. doi: 10.18632/oncotarget.11890.
876 Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.Arthritis Res Ther. 2010;12(3):R116. doi: 10.1186/ar3053. Epub 2010 Jun 16.
877 ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein.FASEB J. 2006 May;20(7):988-90. doi: 10.1096/fj.05-3877fje. Epub 2006 Apr 3.
878 Deletion of either CD55 or CD97 ameliorates arthritis in mouse models.Arthritis Rheum. 2010 Apr;62(4):1036-42. doi: 10.1002/art.27347.
879 The Rheumatoid Arthritis Risk Gene AIRE Is Induced by Cytokines in Fibroblast-Like Synoviocytes and Augments the Pro-inflammatory Response.Front Immunol. 2019 Jun 18;10:1384. doi: 10.3389/fimmu.2019.01384. eCollection 2019.
880 The transcription factor FBI-1/OCZF/LRF is expressed in osteoclasts and regulates RANKL-induced osteoclast formation in vitro and in vivo.Arthritis Rheum. 2011 Sep;63(9):2744-54. doi: 10.1002/art.30455.
881 Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling.Mol Oncol. 2015 Jan;9(1):17-31. doi: 10.1016/j.molonc.2014.07.010. Epub 2014 Jul 24.
882 Analysis of the candidate gene NRAMP1 in the first 61 ARC National Repository families for rheumatoid arthritis.J Rheumatol. 1997 Jan;24(1):212-4.
883 Activation of nuclear orphan receptor NURR1 transcription by NF-kappa B and cyclic adenosine 5'-monophosphate response element-binding protein in rheumatoid arthritis synovial tissue.J Immunol. 2002 Mar 15;168(6):2979-87. doi: 10.4049/jimmunol.168.6.2979.
884 Phenome-Wide Association Study to Explore Relationships between Immune System Related Genetic Loci and Complex Traits and Diseases.PLoS One. 2016 Aug 10;11(8):e0160573. doi: 10.1371/journal.pone.0160573. eCollection 2016.
885 Gene expression of MASH-1, MATH-1, neuroD and NSCL-2, basic helix-loop-helix proteins, during neural differentiation in P19 embryonal carcinoma cells.Tohoku J Exp Med. 1997 Aug;182(4):327-36. doi: 10.1620/tjem.182.327.
886 A second susceptibility gene for developing rheumatoid arthritis in the human MHC is localized within a 70-kb interval telomeric of the TNF genes in the HLA class III region.Genomics. 2001 Feb 1;71(3):263-70. doi: 10.1006/geno.2000.6371.
887 A new look at the shared epitope hypothesis.Am J Med. 1988 Dec 23;85(6A):20-2. doi: 10.1016/0002-9343(88)90375-0.
888 Distinctive gene expression signatures in rheumatoid arthritis synovial tissue fibroblast cells: correlates with disease activity.Genes Immun. 2007 Sep;8(6):480-91. doi: 10.1038/sj.gene.6364400. Epub 2007 Jun 14.
889 Role of Bcl-3 in the development of follicular helper T cells and in the pathogenesis of rheumatoid arthritis.Arthritis Rheumatol. 2015 Oct;67(10):2651-60. doi: 10.1002/art.39266.
890 Decrease in expression of bone morphogenetic proteins 4 and 5 in synovial tissue of patients with osteoarthritis and rheumatoid arthritis.Arthritis Res Ther. 2006;8(3):R58. doi: 10.1186/ar1923. Epub 2006 Mar 15.
891 HLA-DPB1-COL11A2 and three additional xMHC loci are independently associated with RA in a UK cohort.Genes Immun. 2011 Apr;12(3):169-75. doi: 10.1038/gene.2010.57. Epub 2011 Feb 3.
892 Tacrolimus, a calcineurin inhibitor, overcomes treatment unresponsiveness mediated by P-glycoprotein on lymphocytes in refractory rheumatoid arthritis.J Rheumatol. 2010 Mar;37(3):512-20. doi: 10.3899/jrheum.090048. Epub 2010 Jan 15.
893 Detection of differentially expressed genes in synovial fibroblasts by restriction fragment differential display.Rheumatology (Oxford). 2004 Nov;43(11):1346-52. doi: 10.1093/rheumatology/keh347. Epub 2004 Aug 3.
894 CARD9 mediates dendritic cell-induced development of Lyn deficiency-associated autoimmune and inflammatory diseases.Sci Signal. 2019 Oct 8;12(602):eaao3829. doi: 10.1126/scisignal.aao3829.
895 CASPASE-12 and rheumatoid arthritis in African-Americans.Immunogenetics. 2014 Apr;66(4):281-5. doi: 10.1007/s00251-014-0762-9. Epub 2014 Feb 11.
896 Familial rheumatoid arthritis in patients referred to rheumatology clinics of Tabriz, Iran.Int J Rheum Dis. 2012 Feb;15(1):110-5. doi: 10.1111/j.1756-185X.2011.01664.x. Epub 2011 Sep 14.
897 A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility.Nat Genet. 2010 Jun;42(6):515-9. doi: 10.1038/ng.583. Epub 2010 May 9.
898 Eosinophilic myositis as first manifestation in a patient with type 2 myotonic dystrophy CCTG expansion mutation and rheumatoid arthritis.Neuromuscul Disord. 2015 Feb;25(2):149-52. doi: 10.1016/j.nmd.2014.09.009. Epub 2014 Sep 28.
899 TCR-CD3 gene polymorphisms and expression profile in rheumatoid arthritis.Autoimmunity. 2016 Nov;49(7):466-471. doi: 10.1080/08916934.2016.1174855. Epub 2016 Apr 26.
900 The significance of platelet activation in rheumatoid arthritis.Clin Rheumatol. 2007 May;26(5):768-71. doi: 10.1007/s10067-007-0550-0. Epub 2007 Feb 6.
901 CD84 cell surface signaling molecule: An emerging biomarker and target for cancer and autoimmune disorders.Clin Immunol. 2019 Jul;204:43-49. doi: 10.1016/j.clim.2018.10.017. Epub 2018 Oct 26.
902 Increased expression of C1q receptors on neutrophils from inflammatory joint fluids.Immunol Lett. 1993 May;36(2):195-201. doi: 10.1016/0165-2478(93)90052-4.
903 PSORS1C1 may be involved in rheumatoid arthritis.Immunol Lett. 2013 Jun;153(1-2):9-14. doi: 10.1016/j.imlet.2013.06.001. Epub 2013 Jun 14.
904 High levels of the proNGF peptides LIP1 and LIP2 in the serum and synovial fluid of rheumatoid arthritis patients: evidence for two new cytokines.J Neuroimmunol. 2008 Feb;194(1-2):143-6. doi: 10.1016/j.jneuroim.2007.11.002. Epub 2007 Dec 27.
905 Human secreted stabilin-1-interacting chitinase-like protein aggravates the inflammation associated with rheumatoid arthritis and is a potential macrophage inflammatory regulator in rodents.Arthritis Rheumatol. 2014 May;66(5):1141-52. doi: 10.1002/art.38356.
906 Diagnostic value of glucose-6-phosphate isomerase in rheumatoid arthritis.Clin Chim Acta. 2010 Dec 14;411(23-24):2049-53. doi: 10.1016/j.cca.2010.08.043. Epub 2010 Sep 15.
907 Human endogenous retrovirus HERV-K(HML-2) Rec expression and transcriptional activities in normal and rheumatoid arthritis synovia.J Rheumatol. 2006 Jan;33(1):16-23.
908 Clinicopathological correlations of podoplanin (gp38) expression in rheumatoid synovium and its potential contribution to fibroblast platelet crosstalk.PLoS One. 2014 Jun 16;9(6):e99607. doi: 10.1371/journal.pone.0099607. eCollection 2014.
909 Association of the CTLA-4 gene with rheumatoid arthritis in Chinese Han population.Eur J Hum Genet. 2005 Jul;13(7):823-8. doi: 10.1038/sj.ejhg.5201423.
910 Association of serum lipids with autoantibodies and inflammatory markers in rheumatoid arthritis patients.Clin Chim Acta. 2018 Nov;486:282-290. doi: 10.1016/j.cca.2018.08.028. Epub 2018 Aug 18.
911 Expression and function of microRNA-188-5p in activated rheumatoid arthritis synovial fibroblasts.Int J Clin Exp Pathol. 2015 May 1;8(5):4953-62. eCollection 2015.
912 FK506 augments glucocorticoid-mediated cyclooxygenase-2 down-regulation in human rheumatoid synovial fibroblasts.Lab Invest. 2000 Feb;80(2):135-41. doi: 10.1038/labinvest.3780017.
913 CD13/aminopeptidase N-induced lymphocyte involvement in inflamed joints of patients with rheumatoid arthritis.Arthritis Rheum. 2002 Sep;46(9):2330-8. doi: 10.1002/art.10517.
914 CRABP1 is associated with a poor prognosis in breast cancer: adding to the complexity of breast cancer cell response to retinoic acid.Mol Cancer. 2015 Jul 5;14:129. doi: 10.1186/s12943-015-0380-7.
915 Suppression of vascular permeability and inflammation by targeting of the transcription factor c-Jun.Nat Biotechnol. 2006 Jul;24(7):856-63. doi: 10.1038/nbt1225. Epub 2006 Jul 2.
916 HLA-DR versus HLA-B5-CREG antigens in rheumatoid arthritis (RA).Scand J Rheumatol. 1987;16(4):285-9. doi: 10.3109/03009748709102930.
917 From desk to bed: computational simulations provide indication for rheumatoid arthritis clinical trials.BMC Syst Biol. 2013 Jan 22;7:10. doi: 10.1186/1752-0509-7-10.
918 Effectiveness of etanercept vs cyclophosphamide as treatment for patients with amyloid A amyloidosis secondary to rheumatoid arthritis.Rheumatology (Oxford). 2012 Nov;51(11):2064-9. doi: 10.1093/rheumatology/kes190. Epub 2012 Aug 9.
919 Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins.Arthritis Rheum. 2005 Nov;52(11):3433-8. doi: 10.1002/art.21385.
920 Protective effect of HLA-DRB1*13 alleles during specific phases in the development of ACPA-positive RA.Ann Rheum Dis. 2016 Oct;75(10):1891-8. doi: 10.1136/annrheumdis-2015-207802. Epub 2015 Dec 29.
921 Reduction of in vitro invasion and in vivo cartilage degradation in a SCID mouse model by loss of function of the fibrinolytic system of rheumatoid arthritis synovial fibroblasts.Arthritis Rheum. 2011 Sep;63(9):2584-94. doi: 10.1002/art.30439.
922 Phenotypic and genotypic analysis of mononuclear cells from patients with Felty's syndrome.Ann Rheum Dis. 1990 Feb;49(2):103-6. doi: 10.1136/ard.49.2.103.
923 Isolation of an IgG monoclonal anti-dnaJ antibody from an immunoglobulin combinatorial library from a patient with rheumatoid arthritis.J Rheumatol. 1999 Jul;26(7):1439-45.
924 Smoking induces transcription of the heat shock protein system in the joints.Ann Rheum Dis. 2014 Jul;73(7):1423-6. doi: 10.1136/annrheumdis-2013-204486. Epub 2014 Feb 18.
925 Simultaneous evaluation of in vivo glucocorticoid sensitivity and expression of glucocorticoid receptor alpha-isoform in rheumatoid arthritis patients.Arq Bras Endocrinol Metabol. 2009 Feb;53(1):24-30. doi: 10.1590/s0004-27302009000100005.
926 Downregulation of RCAS1 and upregulation of cytotoxic T cells affects synovial proliferation and apoptosis in rheumatoid arthritis.J Rheumatol. 2008 Sep;35(9):1716-22. Epub 2008 Aug 1.
927 Role of EFNB1 and EFNB2 in Mouse Collagen-Induced Arthritis and Human Rheumatoid Arthritis.Arthritis Rheumatol. 2015 Jul;67(7):1778-88. doi: 10.1002/art.39116.
928 Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus.Hum Mol Genet. 2010 Jun 1;19(11):2313-20. doi: 10.1093/hmg/ddq092. Epub 2010 Mar 1.
929 Identification of citrullinated eukaryotic translation initiation factor 4G1 as novel autoantigen in rheumatoid arthritis.Biochem Biophys Res Commun. 2006 Mar 3;341(1):94-100. doi: 10.1016/j.bbrc.2005.12.160. Epub 2006 Jan 6.
930 Synovial fluid exoglycosidases are predictors of rheumatoid arthritis and are effective in cartilage glycosaminoglycan depletion.Arthritis Rheum. 2003 Aug;48(8):2163-72. doi: 10.1002/art.11093.
931 Comparative Price Analysis of Biological Products for Treatment of Rheumatoid Arthritis.Front Pharmacol. 2018 Sep 20;9:1070. doi: 10.3389/fphar.2018.01070. eCollection 2018.
932 Association between single-nucleotide polymorphisms in the SEC8L1 gene, which encodes a subunit of the exocyst complex, and rheumatoid arthritis in a Japanese population.Arthritis Rheum. 2005 May;52(5):1371-80. doi: 10.1002/art.21013.
933 High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis.Genome Med. 2016 Nov 22;8(1):124. doi: 10.1186/s13073-016-0374-0.
934 Evaluation of 19 autoimmune disease-associated loci with rheumatoid arthritis in a Colombian population: evidence for replication and gene-gene interaction.J Rheumatol. 2011 Sep;38(9):1866-70. doi: 10.3899/jrheum.110199. Epub 2011 Jul 15.
935 Novel approach to identifying autoantibodies in rheumatoid synovitis with a biotinylated human autoantigen library and the enzyme-labeled antigen method.J Immunol Methods. 2013 Jan 31;387(1-2):57-70. doi: 10.1016/j.jim.2012.09.011. Epub 2012 Oct 5.
936 B cells expressing the IgA receptor FcRL4 participate in the autoimmune response in patients with rheumatoid arthritis.J Autoimmun. 2017 Jul;81:34-43. doi: 10.1016/j.jaut.2017.03.004. Epub 2017 Mar 24.
937 Association of forkhead box J3 (FOXJ3) polymorphisms with rheumatoid arthritis.Mol Med Rep. 2013 Oct;8(4):1235-41. doi: 10.3892/mmr.2013.1623. Epub 2013 Aug 9.
938 Peripheral blood gene expression profiling in rheumatoid arthritis.Genes Immun. 2005 Aug;6(5):388-97. doi: 10.1038/sj.gene.6364209.
939 Involvement of membrane protein GDE2 in retinoic acid-induced neurite formation in Neuro2A cells.FEBS Lett. 2007 Feb 20;581(4):712-8. doi: 10.1016/j.febslet.2007.01.035. Epub 2007 Jan 24.
940 Polymorphisms in the glucocorticoid receptor gene and in the glucocorticoid-induced transcript 1 gene are associated with disease activity and response to glucocorticoid bridging therapy in rheumatoid arthritis.Rheumatol Int. 2015 Aug;35(8):1325-33. doi: 10.1007/s00296-015-3235-z. Epub 2015 Feb 28.
941 Association of IL-2RA and IL-2RB genes with erosive status in early rheumatoid arthritis patients (ESPOIR and RMP cohorts).Joint Bone Spine. 2014 May;81(3):228-34. doi: 10.1016/j.jbspin.2013.10.002. Epub 2013 Nov 5.
942 Lack of an association of GNB3 C825T polymorphism and blood pressure in patients with rheumatoid arthritis.Clin Exp Hypertens. 2009 Jul;31(5):428-39. doi: 10.1080/10641960802668748.
943 Induction of a CXCL8 binding site on endothelial syndecan-3 in rheumatoid synovium.Arthritis Rheum. 2005 Aug;52(8):2331-42. doi: 10.1002/art.21222.
944 Genetic variations in GPSM3 associated with protection from rheumatoid arthritis affect its transcript abundance.Genes Immun. 2016 Mar;17(2):139-47. doi: 10.1038/gene.2016.3. Epub 2016 Jan 28.
945 Modulation of synovial cell function by somatostatin in patients with rheumatoid arthritis.Arthritis Rheum. 1997 Dec;40(12):2128-38. doi: 10.1002/art.1780401206.
946 Gastrin-releasing peptide and its receptor increase arthritis fibroblast-like synoviocytes invasiveness through activating the PI3K/AKT pathway.Peptides. 2017 Sep;95:57-61. doi: 10.1016/j.peptides.2017.07.008. Epub 2017 Jul 18.
947 Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12.Am J Hum Genet. 2012 Mar 9;90(3):524-32. doi: 10.1016/j.ajhg.2012.01.010. Epub 2012 Feb 23.
948 Glucocorticoids inhibit induced and non-induced mRNA accumulation of genes encoding hyaluronan synthases (HAS): hydrocortisone inhibits HAS1 activation by blocking the p38 mitogen-activated protein kinase signalling pathway.Rheumatology (Oxford). 2004 Feb;43(2):164-9. doi: 10.1093/rheumatology/keh014. Epub 2003 Sep 16.
949 Occurrence of autoimmune diseases and relationship of autoantibody expression with HLA phenotypes in multicase rheumatoid arthritis families.Scand J Rheumatol. 1993;22(4):152-7. doi: 10.3109/03009749309099263.
950 Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes.Nat Commun. 2018 May 15;9(1):1921. doi: 10.1038/s41467-018-04310-9.
951 Genome-wide DNA methylation patterns in CD4+ T cells from Chinese Han patients with rheumatoid arthritis. Mod Rheumatol. 2017 May;27(3):441-447.
952 Up-regulation of HOXC6, HOXD1, and HOXD8 homeobox gene expression in human neuroblastoma cells following chemical induction of differentiation.Tumour Biol. 1996;17(1):34-47. doi: 10.1159/000217965.
953 Heat shock protein gene expression profile may differentiate between rheumatoid arthritis, osteoarthritis, and healthy controls.Scand J Rheumatol. 2011;40(5):354-7. doi: 10.3109/03009742.2011.552522. Epub 2011 Mar 21.
954 The physiologic increase in expression of some type I IFN-inducible genes during pregnancy is not associated with improved disease activity in pregnant patients with rheumatoid arthritis.Transl Res. 2013 Jun;161(6):505-12. doi: 10.1016/j.trsl.2013.02.007. Epub 2013 Mar 16.
955 MMP-3 expression and release by rheumatoid arthritis fibroblast-like synoviocytes induced with a bacterial ligand of integrin alpha5beta1.Arthritis Res Ther. 2005;7(1):R118-26. doi: 10.1186/ar1462. Epub 2004 Nov 24.
956 Effects of inflammatory cytokine IL-27 on the activation of fibroblast-like synoviocytes in rheumatoid arthritis.Arthritis Res Ther. 2010;12(4):R129. doi: 10.1186/ar3067. Epub 2010 Jul 6.
957 The correlation between interleukin-34 and bone erosion under ultrasound in rheumatoid arthritis.Mod Rheumatol. 2020 Mar;30(2):269-275. doi: 10.1080/14397595.2019.1593576. Epub 2019 Apr 16.
958 The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes.Arthritis Res Ther. 2006;8(3):R80. doi: 10.1186/ar1946. Epub 2006 Apr 28.
959 Identification of a two-loci epistatic interaction associated with susceptibility to rheumatoid arthritis through reverse engineering and multifactor dimensionality reduction.Genomics. 2007 Jul;90(1):6-13. doi: 10.1016/j.ygeno.2007.03.011. Epub 2007 May 4.
960 IRF4 and IRGs Delineate Clinically Relevant Gene Expression Signatures in Systemic Lupus Erythematosus and Rheumatoid Arthritis.Front Immunol. 2019 Jan 7;9:3085. doi: 10.3389/fimmu.2018.03085. eCollection 2018.
961 Inducible but not endothelial nitric oxide synthase polymorphism is associated with susceptibility to rheumatoid arthritis in northwest Spain.Rheumatology (Oxford). 2004 Sep;43(9):1182-5. doi: 10.1093/rheumatology/keh283. Epub 2004 Jun 29.
962 Polymorphism and expression of the galactosyltransferase-associated protein kinase gene in normal individuals and galactosylation-defective rheumatoid arthritis patients.Arthritis Rheum. 1990 Nov;33(11):1655-64. doi: 10.1002/art.1780331108.
963 Human parvovirus B19 transgenic mice become susceptible to polyarthritis.J Immunol. 2004 Oct 1;173(7):4675-83. doi: 10.4049/jimmunol.173.7.4675.
964 Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.Nat Commun. 2016 Aug 23;7:12460. doi: 10.1038/ncomms12460.
965 Associations of killer cell immunoglobulin like receptors with rheumatoid arthritis among North Indian population.Hum Immunol. 2014 Aug;75(8):802-7. doi: 10.1016/j.humimm.2014.05.014. Epub 2014 Jun 6.
966 Killer cell immunoglobulin-like receptor gene's repertoire in rheumatoid arthritis.Scand J Rheumatol. 2006 Mar-Apr;35(2):124-7. doi: 10.1080/03009740500381252.
967 FGF23-Klotho axis in patients with rheumatoid arthritis.Clin Exp Rheumatol. 2020 Jan-Feb;38(1):50-57. Epub 2019 Apr 16.
968 KPNA2 Contributes to the Inflammatory Processes in Synovial Tissue of Patients with Rheumatoid Arthritis and SW982 Cells.Inflammation. 2015 Dec;38(6):2224-34. doi: 10.1007/s10753-015-0205-2.
969 KRN/I-Ag7 mouse arthritis is independent of complement C3.J Clin Immunol. 2011 Oct;31(5):857-63. doi: 10.1007/s10875-011-9562-2. Epub 2011 Jul 6.
970 Association of chondromodulin-II Val58Ile polymorphism with radiographic joint destruction in rheumatoid arthritis.J Rheumatol. 2005 Sep;32(9):1654-61.
971 Association of LILRA2 (ILT1, LIR7) splice site polymorphism with systemic lupus erythematosus and microscopic polyangiitis.Genes Immun. 2008 Apr;9(3):214-23. doi: 10.1038/gene.2008.5. Epub 2008 Feb 14.
972 Retinoic acid receptors and GATA transcription factors activate the transcription of the human lecithin:retinol acyltransferase gene.Int J Biochem Cell Biol. 2009 Mar;41(3):546-53. doi: 10.1016/j.biocel.2008.06.007. Epub 2008 Jul 4.
973 Leucine rich -2 glycoprotein is a potential urinary biomarker for renal tubular injury.Biochem Biophys Res Commun. 2018 Apr 15;498(4):1045-1051. doi: 10.1016/j.bbrc.2018.03.111. Epub 2018 Mar 17.
974 Leukocyte-specific protein 1 regulates T-cell migration in rheumatoid arthritis.Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6535-43. doi: 10.1073/pnas.1514152112. Epub 2015 Nov 9.
975 Identification of genes modulated in rheumatoid arthritis using complementary DNA microarray analysis of lymphoblastoid B cell lines from disease-discordant monozygotic twins.Arthritis Rheum. 2006 Jul;54(7):2047-60. doi: 10.1002/art.21953.
976 Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis: a two-year prospective study (the DAMAGE study cohort).Arthritis Rheum. 2006 Apr;54(4):1122-31. doi: 10.1002/art.21749.
977 The L1 retroelement-related p40 protein induces p38delta MAP kinase.Autoimmunity. 2004 Feb;37(1):57-65. doi: 10.1080/08916930310001637977.
978 Immunochip identifies novel, and replicates known, genetic risk loci for rheumatoid arthritis in black South Africans.Mol Med. 2014 Aug 14;20(1):341-9. doi: 10.2119/molmed.2014.00097.
979 CD161 receptor participates in both impairing NK cell cytotoxicity and the response to glycans and vimentin in patients with rheumatoid arthritis.Clin Immunol. 2010 Jul;136(1):139-47. doi: 10.1016/j.clim.2010.03.005. Epub 2010 Mar 31.
980 MICB*002 and MICB*014 protect against rheumatoid arthritis, whereas MICA*009 and MICA*A6 are associated with rheumatoid arthritis in a Hainan Han Chinese population.Int J Rheum Dis. 2019 Jan;22(1):90-95. doi: 10.1111/1756-185X.13302. Epub 2018 Apr 17.
981 Diet-induced obesity and reduced skin cancer susceptibility in matrix metalloproteinase 19-deficient mice.Mol Cell Biol. 2004 Jun;24(12):5304-13. doi: 10.1128/MCB.24.12.5304-5313.2004.
982 Expression of cAMP response element binding protein (CREB)-binding protein (CBP) and the implication in retinoic acid-inducible transcription activation in human salivary gland adenocarcinoma cell line HSG.Endocr Res. 2003 Aug;29(3):277-89. doi: 10.1081/erc-120025035.
983 miR?60 regulates skeletal muscle proliferation in rheumatoid arthritis by targeting Myo18b.Mol Med Rep. 2019 Dec;20(6):4843-4854. doi: 10.3892/mmr.2019.10775. Epub 2019 Oct 29.
984 Aggregation of rare/low-frequency variants of the mitochondria respiratory chain-related proteins in rheumatoid arthritis patients.J Hum Genet. 2015 Aug;60(8):449-54. doi: 10.1038/jhg.2015.50. Epub 2015 May 28.
985 Role of IL-17 in the Th1 systemic defects in rheumatoid arthritis through selective IL-12Rbeta2 inhibition.Ann Rheum Dis. 2010 Aug;69(8):1562-7. doi: 10.1136/ard.2009.111757. Epub 2010 Jun 11.
986 Association of the Smad3 and NFATc2 gene polymorphisms and their serum levels with susceptibility to rheumatoid arthritis in Polish cohorts.Clin Exp Immunol. 2015 Mar;179(3):444-53. doi: 10.1111/cei.12482.
987 TNF- modulates expression of the circadian clock gene Per2 in rheumatoid synovial cells.Scand J Rheumatol. 2013;42(4):276-80. doi: 10.3109/03009742.2013.765031. Epub 2013 Mar 16.
988 Identification of the NF-B activating protein-like locus as a risk locus for rheumatoid arthritis.Ann Rheum Dis. 2013 Jul;72(7):1249-54. doi: 10.1136/annrheumdis-2012-202076. Epub 2012 Dec 6.
989 Association of polymorphisms in SPARC and NLRP2 genes with rheumatoid arthritis in a Chinese Han population.Mod Rheumatol. 2015 Jan;25(1):67-71. doi: 10.3109/14397595.2014.903595. Epub 2014 Apr 23.
990 Somatic cell plasticity and Niemann-Pick type C2 protein: fibroblast activation.J Biol Chem. 2011 Jan 21;286(3):2078-87. doi: 10.1074/jbc.M110.135897. Epub 2010 Nov 17.
991 COUP-TFI (chicken ovalbumin upstream promoter-transcription factor I) regulates cell migration and axogenesis in differentiating P19 embryonal carcinoma cells.Mol Endocrinol. 2000 Dec;14(12):1918-33. doi: 10.1210/mend.14.12.0562.
992 Expression analysis of Notch-related molecules in peripheral blood T helper cells of patients with rheumatoid arthritis.Scand J Rheumatol. 2010;39(1):26-32. doi: 10.3109/03009740903124424.
993 Olf1/EBF associated zinc finger protein interfered with antinuclear antibody production in patients with systemic lupus erythematosus.Arthritis Res Ther. 2010;12(2):R59. doi: 10.1186/ar2972. Epub 2010 Apr 1.
994 Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor.Arthritis Rheum. 2000 Feb;43(2):250-8. doi: 10.1002/1529-0131(200002)43:2<250::AID-ANR3>3.0.CO;2-P.
995 Putative role of functional interferon regulatory factor 5 (IRF5) polymorphism in rheumatoid arthritis in a Korean population.J Rheumatol. 2008 Nov;35(11):2106-18. doi: 10.3899/jrheum.080114. Epub 2008 Oct 1.
996 Identification of candidate synovial membrane biomarkers after Achyranthes aspera treatment for rheumatoid arthritis.Biochim Biophys Acta. 2016 Mar;1864(3):308-316. doi: 10.1016/j.bbapap.2015.12.010. Epub 2015 Dec 24.
997 Circadian rhythms of cellular immunity in rheumatoid arthritis: a hypothesis-generating study.Clin Exp Rheumatol. 2015 Jan-Feb;33(1):34-43. Epub 2014 Dec 22.
998 PGK1, a glucose metabolism enzyme, may play an important role in rheumatoid arthritis.Inflamm Res. 2016 Oct;65(10):815-25. doi: 10.1007/s00011-016-0965-7. Epub 2016 Jun 24.
999 Vitamin A is required for regulation of polymeric immunoglobulin receptor (pIgR) expression by interleukin-4 and interferon-gamma in a human intestinal epithelial cell line.J Nutr. 1998 Jul;128(7):1063-9. doi: 10.1093/jn/128.7.1063.
1000 Proteins related to the functions of fibroblast-like synoviocytes identified by proteomic analysis.Clin Exp Rheumatol. 2012 Mar-Apr;30(2):213-21. Epub 2012 Apr 13.
1001 Induction of p21(CIP1/Waf1) and activation of p34(cdc2) involved in retinoic acid-induced apoptosis in human hepatoma Hep3B cells.Exp Cell Res. 1999 Apr 10;248(1):87-96. doi: 10.1006/excr.1999.4397.
1002 Evaluation of SUMO1 and POU2AF1 in whole blood from rheumatoid arthritis patients and at risk relatives.Int J Immunogenet. 2019 Apr;46(2):59-66. doi: 10.1111/iji.12414. Epub 2019 Jan 25.
1003 Involvement of simultaneous multiple transcription factor expression, including cAMP responsive element binding protein and OCT-1, for synovial cell outgrowth in patients with rheumatoid arthritis.Ann Rheum Dis. 1998 Aug;57(8):487-94. doi: 10.1136/ard.57.8.487.
1004 Deflazacort modulates the fibrinolytic pattern and reduces uPA-dependent chemioinvasion and proliferation in rheumatoid arthritis synoviocytes.Rheumatology (Oxford). 2005 Oct;44(10):1255-62. doi: 10.1093/rheumatology/kei006. Epub 2005 Jul 5.
1005 The role of eight polymorphisms in three candidate genes in determining the susceptibility, phenotype, and response to anti-TNF therapy in patients with rheumatoid arthritis.Clin Exp Rheumatol. 2012 Nov-Dec;30(6):939-42. Epub 2012 Dec 17.
1006 Prothymosin alpha lacking the nuclear localization signal as an effective gene therapeutic strategy in collagen-induced arthritis.J Immunol. 2007 Apr 1;178(7):4688-94. doi: 10.4049/jimmunol.178.7.4688.
1007 The Gene Curation Coalition: A global effort to harmonize gene-disease evidence resources. Genet Med. 2022 Aug;24(8):1732-1742. doi: 10.1016/j.gim.2022.04.017. Epub 2022 May 4.
1008 CTLA-4IG suppresses reactive oxygen species by preventing synovial adherent cell-induced inactivation of Rap1, a Ras family GTPASE mediator of oxidative stress in rheumatoid arthritis T cells.Arthritis Rheum. 2006 Oct;54(10):3135-43. doi: 10.1002/art.22139.
1009 Transmembrane BAFF from rheumatoid synoviocytes requires interleukin-6 to induce the expression of recombination-activating gene in B lymphocytes.Arthritis Rheum. 2009 May;60(5):1261-71. doi: 10.1002/art.24498.
1010 Subjective Complaints as the Main Reason for Biosimilar Discontinuation After Open-Label Transition From Reference Infliximab to Biosimilar Infliximab.Arthritis Rheumatol. 2018 Jan;70(1):60-68. doi: 10.1002/art.40324. Epub 2017 Dec 7.
1011 Transcriptional regulation of Rex1 (zfp42) in normal prostate epithelial cells and prostate cancer cells.J Cell Physiol. 2010 Jul;224(1):17-27. doi: 10.1002/jcp.22071.
1012 Influence of Extracellular RNAs, Released by Rheumatoid Arthritis Synovial Fibroblasts, on Their Adhesive and Invasive Properties.J Immunol. 2016 Oct 1;197(7):2589-97. doi: 10.4049/jimmunol.1501580. Epub 2016 Aug 22.
1013 Slit3 inhibits Robo3-induced invasion of synovial fibroblasts in rheumatoid arthritis.Arthritis Res Ther. 2010;12(2):R45. doi: 10.1186/ar2955. Epub 2010 Mar 18.
1014 Anti-citrullinated glucose-6-phosphate isomerase peptide antibodies in patients with rheumatoid arthritis are associated with HLA-DRB1 shared epitope alleles and disease activity.Clin Exp Immunol. 2013 Apr;172(1):44-53. doi: 10.1111/cei.12033.
1015 Functional variants in NFKBIE and RTKN2 involved in activation of the NF-B pathway are associated with rheumatoid arthritis in Japanese.PLoS Genet. 2012 Sep;8(9):e1002949. doi: 10.1371/journal.pgen.1002949. Epub 2012 Sep 13.
1016 SPACIA1/SAAL1 Deletion Results in a Moderate Delay in Collagen-Induced Arthritis Activity, along with mRNA Decay of Cyclin-dependent Kinase 6 Gene.Int J Mol Sci. 2018 Nov 30;19(12):3828. doi: 10.3390/ijms19123828.
1017 DNA polymorphism of immunoglobulin kappa confers risk of rheumatoid arthritis.Arthritis Rheum. 1989 May;32(5):634-7. doi: 10.1002/anr.1780320518.
1018 Evidence of epistasis between interleukin 1 and selenoprotein-S with susceptibility to rheumatoid arthritis.Ann Rheum Dis. 2009 Sep;68(9):1494-7. doi: 10.1136/ard.2008.090001. Epub 2008 Aug 26.
1019 Gingival crevicular fluid tissue/blood vessel-type plasminogen activator and plasminogen activator inhibitor-2 levels in patients with rheumatoid arthritis: effects of nonsurgical periodontal therapy.J Periodontal Res. 2017 Jun;52(3):574-581. doi: 10.1111/jre.12425. Epub 2016 Oct 26.
1020 Secreted frizzled-related protein 5 suppresses inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes through down-regulation of c-Jun N-terminal kinase.Rheumatology (Oxford). 2014 Sep;53(9):1704-11. doi: 10.1093/rheumatology/keu167. Epub 2014 Apr 24.
1021 Loss of SH3 domain-binding protein 2 function suppresses bone destruction in tumor necrosis factor-driven and collagen-induced arthritis in mice.Arthritis Rheumatol. 2015 Mar;67(3):656-67. doi: 10.1002/art.38975.
1022 Lack of association between rare mutations of the SIAE gene and rheumatoid arthritis in a Han Chinese population.Genet Mol Res. 2015 Oct 30;14(4):14162-8. doi: 10.4238/2015.October.29.38.
1023 Expression of soluble human signaling lymphocytic activation molecule in vivo.J Allergy Clin Immunol. 1999 Jan;103(1 Pt 1):114-8. doi: 10.1016/s0091-6749(99)70534-8.
1024 Polymorphism of the human immunoglobulin heavy chain locus in rheumatoid arthritis.Autoimmunity. 1997;25(2):109-16. doi: 10.3109/08916939708996277.
1025 A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis.Arthritis Rheumatol. 2017 May;69(5):976-985. doi: 10.1002/art.40051. Epub 2017 Mar 31.
1026 SNAPIN: an endogenous Toll-like receptor ligand in rheumatoid arthritis.Ann Rheum Dis. 2012 Aug;71(8):1411-7. doi: 10.1136/annrheumdis-2011-200899. Epub 2012 Apr 20.
1027 Developmental considerations of sperm protein 17 gene expression in rheumatoid arthritis synoviocytes.Dev Immunol. 2002 Jun;9(2):97-102. doi: 10.1080/1044667021000095186.
1028 Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis.Ann Rheum Dis. 2014 Nov;73(11):2038-46. doi: 10.1136/annrheumdis-2013-204050. Epub 2013 Aug 16.
1029 Serum response elements activate and cAMP responsive elements inhibit expression of transcription factor Egr-1 in synovial fibroblasts of rheumatoid arthritis patients.Int Immunol. 1999 Jan;11(1):47-61. doi: 10.1093/intimm/11.1.47.
1030 Association of increased frequencies of HLA-DPB1*05:01 with the presence of anti-Ro/SS-A and anti-La/SS-B antibodies in Japanese rheumatoid arthritis and systemic lupus erythematosus patients.PLoS One. 2013;8(1):e53910. doi: 10.1371/journal.pone.0053910. Epub 2013 Jan 8.
1031 Association of familial and sporadic rheumatoid arthritis with a single corticotropin-releasing hormone genomic region (8q12.3) haplotype.Arthritis Rheum. 2002 Jan;46(1):75-82. doi: 10.1002/1529-0131(200201)46:1<75::AID-ART10034>3.0.CO;2-3.
1032 Stra6, a retinoic acid-responsive gene, participates in p53-induced apoptosis after DNA damage.Cell Death Differ. 2013 Jul;20(7):910-9. doi: 10.1038/cdd.2013.14. Epub 2013 Mar 1.
1033 CD6 and syntaxin binding protein 6 variants and response to tumor necrosis factor alpha inhibitors in Danish patients with rheumatoid arthritis.PLoS One. 2012;7(6):e38539. doi: 10.1371/journal.pone.0038539. Epub 2012 Jun 7.
1034 A novel nonsense variant in SUPT20H gene associated with Rheumatoid Arthritis identified by Whole Exome Sequencing of multiplex families.PLoS One. 2019 Mar 7;14(3):e0213387. doi: 10.1371/journal.pone.0213387. eCollection 2019.
1035 SUMO4 and MAP3K7IP2 single nucleotide polymorphisms and susceptibility to rheumatoid arthritis.J Rheumatol. 2006 Jun;33(6):1048-51.
1036 A specific p47phox -serine phosphorylated by convergent MAPKs mediates neutrophil NADPH oxidase priming at inflammatory sites.J Clin Invest. 2006 Jul;116(7):2033-43. doi: 10.1172/JCI27544. Epub 2006 Jun 15.
1037 Tespa1 is associated with susceptibility but not severity of rheumatoid arthritis in the Zhejiang Han population in China.Clin Rheumatol. 2015 Apr;34(4):665-71. doi: 10.1007/s10067-015-2900-7. Epub 2015 Mar 4.
1038 Evaluation of amplicor chlamydia PCR and LCX chlamydia LCR to detect Chlamydia trachomatis in synovial fluid.Clin Exp Rheumatol. 2002 Mar-Apr;20(2):185-92.
1039 Joint damage is amplified in rheumatoid arthritis patients with positive thyroid autoantibodies.PeerJ. 2018 Jan 4;6:e4216. doi: 10.7717/peerj.4216. eCollection 2018.
1040 A novel T cell cytokine, secreted osteoclastogenic factor of activated T cells, induces osteoclast formation in a RANKL-independent manner.Arthritis Rheum. 2009 Nov;60(11):3324-35. doi: 10.1002/art.24877.
1041 TMEM187-IRAK1 Polymorphisms Associated with Rheumatoid Arthritis Susceptibility in Tunisian and French Female Populations: Influence of Geographic Origin.J Immunol Res. 2017;2017:4915950. doi: 10.1155/2017/4915950. Epub 2017 Feb 8.
1042 Serum concentrations of soluble 4-1BB and 4-1BB ligand correlated with the disease severity in rheumatoid arthritis.Exp Mol Med. 2004 Feb 29;36(1):13-22. doi: 10.1038/emm.2004.2.
1043 A pro-inflammatory role for A20 and ABIN family proteins in human fibroblast-like synoviocytes in rheumatoid arthritis.Immunol Lett. 2012 Jan 30;141(2):246-53. doi: 10.1016/j.imlet.2011.10.011. Epub 2011 Nov 9.
1044 Investigation of association between the TRAF family genes and RA susceptibility.Ann Rheum Dis. 2007 Oct;66(10):1322-6. doi: 10.1136/ard.2006.065706. Epub 2007 Feb 2.
1045 Clinical associations of the positive anti Ro52 without Ro60 autoantibodies: undifferentiated connective tissue diseases.J Clin Pathol. 2018 Jan;71(1):12-19. doi: 10.1136/jclinpath-2015-203587. Epub 2017 Jun 29.
1046 Deduction of Novel Genes Potentially Involved in Osteoblasts of Rheumatoid Arthritis Using Next-Generation Sequencing and Bioinformatic Approaches.Int J Mol Sci. 2017 Nov 11;18(11):2396. doi: 10.3390/ijms18112396.
1047 Brief Report: Peripheral Osteolysis in Adults Linked to ASAH1 (Acid Ceramidase) Mutations: A New Presentation of Farber's Disease.Arthritis Rheumatol. 2016 Sep;68(9):2323-7. doi: 10.1002/art.39659. Epub 2016 Jul 29.
1048 The Role of Cdkn1A-Interacting Zinc Finger Protein 1 (CIZ1) in DNA Replication and Pathophysiology.Int J Mol Sci. 2016 Feb 5;17(2):212. doi: 10.3390/ijms17020212.
1049 A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus.Ann Rheum Dis. 2017 Jan;76(1):286-294. doi: 10.1136/annrheumdis-2016-209436. Epub 2016 May 18.
1050 A Retrospective Analysis of Subaxial Subluxation After Atlanto-axial Arthrodesis in Patients With Rheumatoid Arthritis Based on Annual Radiographs Obtained for 5 Years.Clin Spine Surg. 2017 Jun;30(5):E598-E602. doi: 10.1097/BSD.0000000000000277.
1051 TDAG8, TRPV1, and ASIC3 involved in establishing hyperalgesic priming in experimental rheumatoid arthritis.Sci Rep. 2017 Aug 21;7(1):8870. doi: 10.1038/s41598-017-09200-6.
1052 Increased sensitivity of rheumatoid synoviocytes to Schnurri-3 expression in TNF- and IL-17A induced osteoblastic differentiation.Bone. 2016 Jun;87:89-96. doi: 10.1016/j.bone.2016.04.008. Epub 2016 Apr 9.
1053 Imbalance of circulating Tfr/Tfh ratio in patients with rheumatoid arthritis.Clin Exp Med. 2019 Feb;19(1):55-64. doi: 10.1007/s10238-018-0530-5. Epub 2018 Oct 4.
1054 Rheumatoid arthritis and periodontal disease: What are the similarities and differences?.Int J Rheum Dis. 2017 Dec;20(12):1887-1901. doi: 10.1111/1756-185X.13240. Epub 2018 Jan 9.
1055 IL-9 receptor: Regulatory role on FLS and pannus formation.Cytokine. 2018 Nov;111:58-62. doi: 10.1016/j.cyto.2018.08.001. Epub 2018 Aug 14.
1056 Constitutive Activation of Integrin 9 Augments Self-Directed Hyperplastic and Proinflammatory Properties of Fibroblast-like Synoviocytes of Rheumatoid Arthritis.J Immunol. 2017 Nov 15;199(10):3427-3436. doi: 10.4049/jimmunol.1700941. Epub 2017 Oct 16.
1057 Upregulated KAT7 in synovial fibroblasts promotes Th17cell differentiation and infiltration in rheumatoid arthritis.Biochem Biophys Res Commun. 2017 Jul 22;489(2):235-241. doi: 10.1016/j.bbrc.2017.05.143. Epub 2017 May 26.
1058 Cross talk between progesterone receptors and retinoic acid receptors in regulation of cytokeratin 5-positive breast cancer cells.Oncogene. 2017 Nov 2;36(44):6074-6084. doi: 10.1038/onc.2017.204. Epub 2017 Jul 10.
1059 Meta-analysis: diagnostic accuracy of antibody against peptidylarginine deiminase 4 by ELISA for rheumatoid arthritis.Clin Rheumatol. 2017 Nov;36(11):2431-2438. doi: 10.1007/s10067-017-3809-0. Epub 2017 Sep 8.
1060 Heterogeneity of the Type I Interferon Signature in Rheumatoid Arthritis: A Potential Limitation for Its Use As a Clinical Biomarker.Front Immunol. 2018 Jan 16;8:2007. doi: 10.3389/fimmu.2017.02007. eCollection 2017.
1061 Pharmacokinetics of LBPT and its primary metabolites, as well as tolerability in the first-in-human study.Eur J Pharm Sci. 2017 Mar 30;100:87-93. doi: 10.1016/j.ejps.2016.12.038. Epub 2017 Jan 3.
1062 TIPE2 expression is increased in peripheral blood mononuclear cells from patients with rheumatoid arthritis.Oncotarget. 2017 Sep 23;8(50):87472-87479. doi: 10.18632/oncotarget.21267. eCollection 2017 Oct 20.
1063 Osteoblastic PLEKHO1 contributes to joint inflammation in rheumatoid arthritis.EBioMedicine. 2019 Mar;41:538-555. doi: 10.1016/j.ebiom.2019.02.009. Epub 2019 Feb 26.
1064 Identification of novel genetic loci for osteoporosis and/or rheumatoid arthritis using cFDR approach.PLoS One. 2017 Aug 30;12(8):e0183842. doi: 10.1371/journal.pone.0183842. eCollection 2017.
1065 Unfolded protein response gene GADD34 is overexpressed in rheumatoid arthritis and related to the presence of circulating anti-citrullinated protein antibodies.Autoimmunity. 2016;49(3):172-8. doi: 10.3109/08916934.2016.1138220. Epub 2016 Feb 1.
1066 Exacerbation of collagen antibody-induced arthritis in transgenic mice overexpressing peroxiredoxin 6.Arthritis Rheumatol. 2015 Nov;67(11):3058-69. doi: 10.1002/art.39284.
1067 Muscle Deficits in Rheumatoid Arthritis Contribute to Inferior Cortical Bone Structure and Trabecular Bone Mineral Density.J Rheumatol. 2017 Dec;44(12):1777-1785. doi: 10.3899/jrheum.170513. Epub 2017 Sep 15.
1068 Lipopolysaccharide mediates hepatic stellate cell activation by regulating autophagy and retinoic acid signaling.Autophagy. 2017;13(11):1813-1827. doi: 10.1080/15548627.2017.1356550. Epub 2017 Nov 21.
1069 Identification and Validation of SAA4 as a Rheumatoid Arthritis Prescreening Marker by Liquid Chromatography Tandem-mass Spectrometry.Molecules. 2017 May 14;22(5):805. doi: 10.3390/molecules22050805.
1070 Biological function integrated prediction of severe radiographic progression in rheumatoid arthritis: a nested case control study.Arthritis Res Ther. 2017 Oct 25;19(1):244. doi: 10.1186/s13075-017-1414-x.
1071 Genetic regulation of dimethylarginines and endothelial dysfunction in rheumatoid arthritis.Amino Acids. 2019 Jul;51(7):983-990. doi: 10.1007/s00726-019-02740-3. Epub 2019 May 6.
1072 The contribution of methotrexate exposure and host factors on transcriptional variance in human liver. Toxicol Sci. 2007 Jun;97(2):582-94.
1073 Cross-Sectional Evaluation of Periodontal Status and Microbiologic and Rheumatoid Parameters in a Large Cohort of Patients With Rheumatoid Arthritis.J Periodontol. 2017 Apr;88(4):368-379. doi: 10.1902/jop.2016.160355. Epub 2016 Nov 18.
1074 Functional characterisation of ADP ribosylation factor-like protein 15 in rheumatoid arthritis synovial fibroblasts.Clin Exp Rheumatol. 2018 Jul-Aug;36(4):581-588. Epub 2018 Feb 14.
1075 Rheumatoid arthritis reprograms circadian output pathways.Arthritis Res Ther. 2019 Feb 6;21(1):47. doi: 10.1186/s13075-019-1825-y.
1076 Self nanoemulsifying granules (SNEGs) of meloxicam: preparation, characterization, molecular modeling and evaluation of in vivo anti-inflammatory activity.Drug Dev Ind Pharm. 2017 Apr;43(4):600-610. doi: 10.1080/03639045.2016.1275665. Epub 2017 Jan 17.
1077 Investigation of gene expression profiles in a rat adjuvant arthritis model suggests an effective role of triptolide via PI3K-AKT signaling.Exp Ther Med. 2019 May;17(5):3999-4006. doi: 10.3892/etm.2019.7425. Epub 2019 Mar 20.
1078 Diagnostic test accuracy of magnetic resonance imaging and ultrasound for detecting bone erosion in patients with rheumatoid arthritis.Clin Rheumatol. 2020 Apr;39(4):1283-1293. doi: 10.1007/s10067-019-04825-6. Epub 2019 Nov 12.
1079 Systemic Resolvin E1 (RvE1) Treatment Does Not Ameliorate the Severity of Collagen-Induced Arthritis (CIA) in Mice: A Randomized, Prospective, and Controlled Proof of Concept Study.Mediators Inflamm. 2019 Oct 31;2019:5689465. doi: 10.1155/2019/5689465. eCollection 2019.
1080 Soluble syndecan-3 binds chemokines, reduces leukocyte migration in vitro and ameliorates disease severity in models of rheumatoid arthritis.Arthritis Res Ther. 2019 Jul 12;21(1):172. doi: 10.1186/s13075-019-1939-2.
1081 Decoy receptor 3 down-regulates centrosomal protein 70kDa specifically in rheumatoid synovial fibroblasts.Mod Rheumatol. 2018 Mar;28(2):287-292. doi: 10.1080/14397595.2017.1341593. Epub 2017 Jul 11.
1082 CHD7 represses the retinoic acid synthesis enzyme ALDH1A3 during inner ear development.JCI Insight. 2018 Feb 22;3(4):e97440. doi: 10.1172/jci.insight.97440. eCollection 2018 Feb 22.
1083 Localization of quantitative trait loci regulating adjuvant-induced arthritis in rats: evidence for genetic factors common to multiple autoimmune diseases.J Immunol. 1998 Oct 15;161(8):4411-9.
1084 Serum and synovial fluid concentrations of cold-inducible RNA-binding protein in patients with rheumatoid arthritis.Int J Rheum Dis. 2018 Jan;21(1):148-154. doi: 10.1111/1756-185X.12892. Epub 2016 Jun 17.
1085 TNF-induced inflammatory genes escape repression in fibroblast-like synoviocytes: transcriptomic and epigenomic analysis.Ann Rheum Dis. 2019 Sep;78(9):1205-1214. doi: 10.1136/annrheumdis-2018-214783. Epub 2019 May 16.
1086 Synovial GATA1 mediates rheumatoid arthritis progression via transcriptional activation of NOS2 signaling.Microbiol Immunol. 2018 Sep;62(9):594-606. doi: 10.1111/1348-0421.12637. Epub 2018 Aug 13.
1087 Effects of non-surgical periodontal therapy on periodontal laboratory and clinical data as well as on disease activity in patients with rheumatoid arthritis.Clin Oral Investig. 2019 Jan;23(1):141-151. doi: 10.1007/s00784-018-2420-3. Epub 2018 Mar 27.
1088 Two rheumatoid arthritis-specific autoantigens correlate microbial immunity with autoimmune responses in joints. J Clin Invest. 2017 Aug 1;127(8):2946-2956.
1089 RHAMM induces progression of rheumatoid arthritis by enhancing the functions of fibroblast-like synoviocytes.BMC Musculoskelet Disord. 2018 Dec 26;19(1):455. doi: 10.1186/s12891-018-2370-6.
1090 Gene expression profiling meta-analysis reveals novel gene signatures and pathways shared between tuberculosis and rheumatoid arthritis.PLoS One. 2019 Mar 7;14(3):e0213470. doi: 10.1371/journal.pone.0213470. eCollection 2019.
1091 Increased Burden of Psychiatric Disorders in Rheumatoid Arthritis.Arthritis Care Res (Hoboken). 2018 Jul;70(7):970-978. doi: 10.1002/acr.23539. Epub 2018 May 21.
1092 Discovery of circulating proteins associated to knee radiographic osteoarthritis.Sci Rep. 2017 Mar 9;7(1):137. doi: 10.1038/s41598-017-00195-8.
1093 Impaired Tip60-mediated Foxp3 acetylation attenuates regulatory T cell development in rheumatoid arthritis.J Autoimmun. 2019 Jun;100:27-39. doi: 10.1016/j.jaut.2019.02.007. Epub 2019 Apr 4.
1094 Associative role of HLA-DRB1 SNP genotypes as risk factors for susceptibility and severity of rheumatoid arthritis: A North-east Indian population-based study.Int J Immunogenet. 2018 Feb;45(1):1-7. doi: 10.1111/iji.12347. Epub 2017 Nov 23.
1095 Impact of the leucocyte immunoglobulin-like receptor A3 (LILRA3) on susceptibility and subphenotypes of systemic lupus erythematosus and Sjgren's syndrome.Ann Rheum Dis. 2015 Nov;74(11):2070-5. doi: 10.1136/annrheumdis-2013-204441. Epub 2014 Jun 6.
1096 Increased serum levels of microfibrillar-associated protein 4 (MFAP4) are not associated with clinical synovitis in rheumatoid arthritis but may reflect underlying cardiovascular comorbidity.Clin Exp Rheumatol. 2020 Jan-Feb;38(1):122-128. Epub 2019 Aug 27.
1097 The DNA Repair Nuclease MRE11A Functions as a Mitochondrial Protector and Prevents T Cell Pyroptosis and Tissue Inflammation.Cell Metab. 2019 Sep 3;30(3):477-492.e6. doi: 10.1016/j.cmet.2019.06.016. Epub 2019 Jul 18.
1098 Role of NFAT5 in the Immune System and Pathogenesis of Autoimmune Diseases.Front Immunol. 2019 Feb 19;10:270. doi: 10.3389/fimmu.2019.00270. eCollection 2019.
1099 Impaired NFKBIE gene function decreases cellular uptake of methotrexate by down-regulating SLC19A1 expression in a human rheumatoid arthritis cell line.Mod Rheumatol. 2016 Jul;26(4):507-16. doi: 10.3109/14397595.2015.1112481. Epub 2016 Jan 4.
1100 Rising Incidence of Acute Hospital Admissions due to Gout.J Rheumatol. 2020 Apr;47(4):619-623. doi: 10.3899/jrheum.190257. Epub 2019 Sep 15.
1101 Differential expressions of NOD-like receptors and their associations with inflammatory responses in rheumatoid arthritis.Clin Exp Rheumatol. 2017 Jul-Aug;35(4):630-637. Epub 2017 Feb 24.
1102 Secreted Protein Acidic and Rich in Cysteine Mediated Biomimetic Delivery of Methotrexate by Albumin-Based Nanomedicines for Rheumatoid Arthritis Therapy.ACS Nano. 2019 May 28;13(5):5036-5048. doi: 10.1021/acsnano.9b01710. Epub 2019 Apr 25.
1103 Serum PGLYRP? is a highly discriminatory biomarker for the diagnosis of rheumatoid arthritis.Mol Med Rep. 2019 Jan;19(1):589-594. doi: 10.3892/mmr.2018.9632. Epub 2018 Nov 8.
1104 Trypsin-2 degrades human type II collagen and is expressed and activated in mesenchymally transformed rheumatoid arthritis synovitis tissue.Am J Pathol. 2005 Oct;167(4):1119-24. doi: 10.1016/S0002-9440(10)61200-X.
1105 RETRACTED: Bone marrow-derived mesenchymal stem cells-secreted exosomal microRNA-192-5p delays inflammatory response in rheumatoid arthritis.Int Immunopharmacol. 2020 Jan;78:105985. doi: 10.1016/j.intimp.2019.105985. Epub 2019 Nov 24.
1106 Ectopic RASGRP2 (CalDAG-GEFI) expression in rheumatoid synovium contributes to the development of destructive arthritis.Ann Rheum Dis. 2018 Dec;77(12):1765-1772. doi: 10.1136/annrheumdis-2018-213588. Epub 2018 Aug 3.
1107 Calgizzarin (S100A11): a novel inflammatory mediator associated with disease activity of rheumatoid arthritis.Arthritis Res Ther. 2017 Apr 26;19(1):79. doi: 10.1186/s13075-017-1288-y.
1108 The efficacy of motivational counselling and SMS reminders on daily sitting time in patients with rheumatoid arthritis: a randomised controlled trial.Ann Rheum Dis. 2017 Sep;76(9):1603-1606. doi: 10.1136/annrheumdis-2016-210953. Epub 2017 Jun 5.
1109 Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis.Int J Mol Sci. 2019 Apr 18;20(8):1923. doi: 10.3390/ijms20081923.
1110 Hepatocyte growth factor receptor signaling mediates the anti-fibrotic action of 9-cis-retinoic acid in glomerular mesangial cells. Am J Pathol. 2005 Oct;167(4):947-57. doi: 10.1016/S0002-9440(10)61185-6.
1111 Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.Nat Immunol. 2019 Jul;20(7):928-942. doi: 10.1038/s41590-019-0378-1. Epub 2019 May 6.
1112 Citrullinated Aggrecan Epitopes as Targets of Autoreactive CD4+ T Cells in Patients With Rheumatoid Arthritis.Arthritis Rheumatol. 2019 Apr;71(4):518-528. doi: 10.1002/art.40768. Epub 2019 Mar 8.
1113 Association of acid phosphatase locus 1*C allele with the risk of cardiovascular events in rheumatoid arthritis patients.Arthritis Res Ther. 2011 Jul 18;13(4):R116. doi: 10.1186/ar3401.
1114 Prognostic factors of methotrexate-associated lymphoproliferative disorders associated with rheumatoid arthritis and plausible application of biological agents.Mod Rheumatol. 2017 Sep;27(5):773-777. doi: 10.1080/14397595.2016.1259714. Epub 2016 Dec 15.
1115 Counter-regulation of regulatory T cells by autoreactive CD8(+) T cells in rheumatoid arthritis.J Autoimmun. 2019 May;99:81-97. doi: 10.1016/j.jaut.2019.02.001. Epub 2019 Feb 16.
1116 Novel insight into the role of -actinin-1 in rheumatoid arthritis.Discov Med. 2014 Feb;17(92):75-80.
1117 A study of Adenosine-Deaminase genetic polymorphism in rheumatoid arthritis.Int J Immunopathol Pharmacol. 2010 Jul-Sep;23(3):791-5. doi: 10.1177/039463201002300313.
1118 Expression of MDC/CCL22 and its receptor CCR4 in rheumatoid arthritis, psoriatic arthritis and osteoarthritis.Cytokine. 2010 Jan;49(1):24-9. doi: 10.1016/j.cyto.2009.10.005. Epub 2009 Nov 25.
1119 ADAM15 in Apoptosis Resistance of Synovial Fibroblasts: Converting Fas/CD95 Death Signals Into the Activation of Prosurvival Pathways by Calmodulin Recruitment.Arthritis Rheumatol. 2019 Jan;71(1):63-72. doi: 10.1002/art.40667. Epub 2018 Nov 20.
1120 Role of ADAMTS-12 in Protecting Against Inflammatory Arthritis in Mice By Interacting With and Inactivating Proinflammatory Connective Tissue Growth Factor.Arthritis Rheumatol. 2018 Nov;70(11):1745-1756. doi: 10.1002/art.40552. Epub 2018 Sep 24.
1121 Increased adenosine-to-inosine RNA editing in rheumatoid arthritis.J Autoimmun. 2020 Jan;106:102329. doi: 10.1016/j.jaut.2019.102329. Epub 2019 Sep 5.
1122 APL-1, an altered peptide ligand derived from heat-shock protein, alone or combined with methotrexate attenuates murine collagen-induced arthritis.Clin Exp Med. 2017 May;17(2):209-216. doi: 10.1007/s10238-016-0412-7. Epub 2016 May 9.
1123 Adiponectin receptor 1 mediates the difference in adiponectin- induced prostaglandin E2 production in rheumatoid arthritis and osteoarthritis synovial fibroblasts.Chin Med J (Engl). 2011 Dec;124(23):3919-24.
1124 Pathophysiological links between rheumatoid arthritis and the Epstein-Barr virus: an update.Joint Bone Spine. 2007 Oct;74(5):418-26. doi: 10.1016/j.jbspin.2007.05.001. Epub 2007 Jun 8.
1125 The role of synthetic manufactured peptides containing common citrullinated epitopes in rheumatoid arthritis diagnosis.Clin Immunol. 2019 Feb;199:7-11. doi: 10.1016/j.clim.2018.12.004. Epub 2018 Dec 10.
1126 Identification of AHNAK as a novel autoantigen in systemic lupus erythematosus.Biochem Biophys Res Commun. 2002 Mar 8;291(4):951-8. doi: 10.1006/bbrc.2002.6534.
1127 Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis. Arthritis Rheum. 2006 Sep;54(9):2830-9. doi: 10.1002/art.22032.
1128 Apolipoprotein m (APOM) levels and APOM rs805297 G/T polymorphism are associated with increased risk of rheumatoid arthritis.Joint Bone Spine. 2014 Jan;81(1):32-6. doi: 10.1016/j.jbspin.2013.03.017. Epub 2013 May 6.
1129 TIM family gene polymorphism and susceptibility to rheumatoid arthritis: Systematic review and meta-analysis.PLoS One. 2019 Feb 7;14(2):e0211146. doi: 10.1371/journal.pone.0211146. eCollection 2019.
1130 A Truncated Variant of ASCC1, a Novel Inhibitor of NF-B, Is Associated with Disease Severity in Patients with Rheumatoid Arthritis.J Immunol. 2015 Dec 1;195(11):5415-20. doi: 10.4049/jimmunol.1501532. Epub 2015 Oct 26.
1131 HTLV-1, Immune Response and Autoimmunity.Viruses. 2015 Dec 24;8(1):5. doi: 10.3390/v8010005.
1132 Correlations Between Sagittal Spinal Balance and Quality of Life in Rheumatoid Arthritis.Clin Spine Surg. 2017 May;30(4):E412-E417. doi: 10.1097/BSD.0000000000000246.
1133 Substance P receptor (NK1) gene expression in synovial tissue in rheumatoid arthritis and osteoarthritis.Scand J Rheumatol. 1998;27(2):135-41. doi: 10.1080/030097498441010.
1134 Transcriptome study of differential expression in schizophrenia.Hum Mol Genet. 2013 Dec 15;22(24):5001-14. doi: 10.1093/hmg/ddt350. Epub 2013 Jul 30.
1135 Regulation of T cell lineage commitment by SMAR1 during inflammatory & autoimmune diseases.Indian J Med Res. 2015 Oct;142(4):405-13. doi: 10.4103/0971-5916.169198.
1136 Effective quantification of 11 tyrosine kinase inhibitors and caffeine in human plasma by validated LC-MS/MS method with potent phospholipids clean-up procedure. Application to therapeutic drug monitoring.Talanta. 2020 Feb 1;208:120450. doi: 10.1016/j.talanta.2019.120450. Epub 2019 Oct 11.
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1138 Differentially Expressed in Chondrocytes 2 (DEC2) Increases the Expression of IL-1 and Is Abundantly Present in Synovial Membrane in Rheumatoid Arthritis.PLoS One. 2015 Dec 28;10(12):e0145279. doi: 10.1371/journal.pone.0145279. eCollection 2015.
1139 Prevalence of autoimmune diseases and clinical significance of autoantibody profile: Data from National Institute of Hygiene in Rabat, Morocco.Hum Immunol. 2019 Jul;80(7):523-532. doi: 10.1016/j.humimm.2019.02.012. Epub 2019 Feb 23.
1140 CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis.Nat Commun. 2015 Sep 25;6:8483. doi: 10.1038/ncomms9483.
1141 Properdin factor B and complement factor C4 allotypes in rheumatoid arthritis: results of a follow-up study.Hum Immunol. 1992 Feb;33(2):148-51. doi: 10.1016/0198-8859(92)90066-v.
1142 Tylophorine-based compounds are therapeutic in rheumatoid arthritis by targeting the caprin-1 ribonucleoprotein complex and inhibiting expression of associated c-Myc and HIF-1.Pharmacol Res. 2020 Feb;152:104581. doi: 10.1016/j.phrs.2019.104581. Epub 2019 Nov 30.
1143 FLIP and MAPK play crucial roles in the MLN51-mediated hyperproliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis.FEBS J. 2008 Jul;275(14):3546-55. doi: 10.1111/j.1742-4658.2008.06500.x.
1144 Overexpression of a minimal domain of calpastatin suppresses IL-6 production and Th17 development via reduced NF-B and increased STAT5 signals.PLoS One. 2011;6(10):e27020. doi: 10.1371/journal.pone.0027020. Epub 2011 Oct 27.
1145 Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis.Genes Immun. 2010 Mar;11(2):142-54. doi: 10.1038/gene.2009.82. Epub 2009 Oct 29.
1146 Stimulation of osteoclast migration and bone resorption by C-C chemokine ligands 19 and 21.Exp Mol Med. 2017 Jul 21;49(7):e358. doi: 10.1038/emm.2017.100.
1147 Eotaxin-3 gene polymorphisms are associated with rheumatoid arthritis in a Korean population.Hum Immunol. 2005 Mar;66(3):314-20. doi: 10.1016/j.humimm.2005.01.002.
1148 Th22 Cells Promote Osteoclast Differentiation via Production of IL-22 in Rheumatoid Arthritis.Front Immunol. 2018 Dec 10;9:2901. doi: 10.3389/fimmu.2018.02901. eCollection 2018.
1149 Chemokine expression in rheumatoid arthritis (RA): evidence of RANTES and macrophage inflammatory protein (MIP)-1 beta production by synovial T cells.Clin Exp Immunol. 1995 Sep;101(3):398-407. doi: 10.1111/j.1365-2249.1995.tb03126.x.
1150 Expression profiles of human CCN genes in patients with osteoarthritis or rheumatoid arthritis.J Orthop Sci. 2015 Jul;20(4):708-16. doi: 10.1007/s00776-015-0727-3. Epub 2015 May 19.
1151 Association of Dendritic Cell Signatures With Autoimmune Inflammation Revealed by Single-Cell Profiling.Arthritis Rheumatol. 2019 May;71(5):817-828. doi: 10.1002/art.40793. Epub 2019 Apr 6.
1152 Low levels of soluble CD1d protein alters NKT cell function in patients with rheumatoid arthritis.Int J Mol Med. 2009 Oct;24(4):481-6. doi: 10.3892/ijmm_00000256.
1153 Restriction fragment length polymorphism of a lymphocyte surface antigen, Blast-1, in Japanese and Caucasians, and in patients with rheumatoid arthritis.Tissue Antigens. 1990 May;35(5):203-5. doi: 10.1111/j.1399-0039.1990.tb01783.x.
1154 Decrease of CD68 Synovial Macrophages in Celastrol Treated Arthritic Rats.PLoS One. 2015 Dec 11;10(12):e0142448. doi: 10.1371/journal.pone.0142448. eCollection 2015.
1155 Analysis of vascular gene expression in arthritic synovium by laser-mediated microdissection.Arthritis Rheum. 2007 Apr;56(4):1094-105. doi: 10.1002/art.22450.
1156 Comparative effectiveness of TNF inhibitors and tocilizumab with and without conventional synthetic disease-modifying antirheumatic drugs in a pan-European observational cohort of bio-nave patients with rheumatoid arthritis.Semin Arthritis Rheum. 2020 Feb;50(1):17-24. doi: 10.1016/j.semarthrit.2019.06.020. Epub 2019 Jun 28.
1157 MicroRNA-27a Inhibits Cell Migration and Invasion of Fibroblast-Like Synoviocytes by Targeting Follistatin-Like Protein 1 in Rheumatoid Arthritis.Mol Cells. 2016 Aug 31;39(8):611-8. doi: 10.14348/molcells.2016.0103. Epub 2016 Aug 8.
1158 CD318 is a ligand for CD6.Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):E6912-E6921. doi: 10.1073/pnas.1704008114. Epub 2017 Jul 31.
1159 Myeloid calcium binding proteins: expression in the differentiated HL-60 cells and detection in sera of patients with connective tissue diseases.J Biochem. 1990 Oct;108(4):650-3. doi: 10.1093/oxfordjournals.jbchem.a123257.
1160 Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans.Arthritis Rheumatol. 2014 May;66(5):1121-32. doi: 10.1002/art.38353.
1161 Identifying Clinical Factors Associated With Low Disease Activity and Remission of Rheumatoid Arthritis During Pregnancy.Arthritis Care Res (Hoboken). 2017 Sep;69(9):1297-1303. doi: 10.1002/acr.23143. Epub 2017 Aug 13.
1162 Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci.Arthritis Rheum. 2011 Apr;63(4):884-93. doi: 10.1002/art.30235.
1163 A HEV-restricted sulfotransferase is expressed in rheumatoid arthritis synovium and is induced by lymphotoxin-alpha/beta and TNF-alpha in cultured endothelial cells.BMC Immunol. 2005 Mar 7;6:6. doi: 10.1186/1471-2172-6-6.
1164 Treat to target approach for asthma.J Asthma. 2020 Jun;57(6):687-690. doi: 10.1080/02770903.2019.1591443. Epub 2019 Mar 23.
1165 Proteomic surveillance of autoimmunity in osteoarthritis: identification of triosephosphate isomerase as an autoantigen in patients with osteoarthritis.Arthritis Rheum. 2004 May;50(5):1511-21. doi: 10.1002/art.20189.
1166 CIP2A facilitates apoptotic resistance of fibroblast-like synoviocytes in rheumatoid arthritis independent of c-Myc expression.Rheumatol Int. 2013 Sep;33(9):2241-8. doi: 10.1007/s00296-013-2711-6. Epub 2013 Mar 2.
1167 SOCS3 participates in cholinergic pathway regulation of synovitis in rheumatoid arthritis.Connect Tissue Res. 2018 May;59(3):287-294. doi: 10.1080/03008207.2017.1380633. Epub 2017 Oct 4.
1168 A potential role of myeloid DAP12-associating lectin (MDL)-1 in the regulation of inflammation in rheumatoid arthritis patients.PLoS One. 2014 Jan 21;9(1):e86105. doi: 10.1371/journal.pone.0086105. eCollection 2014.
1169 Expression and function of dectin-1 is defective in monocytes from patients with systemic lupus erythematosus and rheumatoid arthritis.J Clin Immunol. 2013 Feb;33(2):368-77. doi: 10.1007/s10875-012-9821-x. Epub 2012 Oct 25.
1170 Expressions of circadian clock genes represent disease activities of RA patients treated with biological DMARDs.Mod Rheumatol. 2020 Mar;30(2):293-300. doi: 10.1080/14397595.2019.1602242. Epub 2019 May 2.
1171 A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides.Ann Rheum Dis. 2015 Mar;74(3):e15. doi: 10.1136/annrheumdis-2013-204591. Epub 2014 Feb 14.
1172 Increased antibody levels to stage-specific Epstein-Barr virus antigens in systemic autoimmune diseases reveal a common pathology.Scand J Clin Lab Invest. 2019 Feb-Apr;79(1-2):7-16. doi: 10.1080/00365513.2018.1550807. Epub 2019 Feb 6.
1173 Polymorphisms of COTL1 gene identified by proteomic approach and their association with autoimmune disorders.Exp Mol Med. 2009 May 31;41(5):354-61. doi: 10.3858/emm.2009.41.5.040.
1174 Mediators of inflammation are down-regulated while apoptosis is up-regulated in rheumatoid arthritis synovial tissue by polymerized collagen.Clin Exp Immunol. 2002 Oct;130(1):140-9. doi: 10.1046/j.1365-2249.2002.01955.x.
1175 Synergistic effect of glucosamine and vitamin E against experimental rheumatoid arthritis in neonatal rats.Biomed Pharmacother. 2018 Sep;105:835-840. doi: 10.1016/j.biopha.2018.05.136. Epub 2018 Jun 18.
1176 Inhibition of angiogenesis by arsenic trioxide via TSP-1-TGF-1-CTGF-VEGF functional module in rheumatoid arthritis.Oncotarget. 2017 Aug 3;8(43):73529-73546. doi: 10.18632/oncotarget.19867. eCollection 2017 Sep 26.
1177 CTHRC1: A New Candidate Biomarker for Improved Rheumatoid Arthritis Diagnosis.Front Immunol. 2019 Jun 12;10:1353. doi: 10.3389/fimmu.2019.01353. eCollection 2019.
1178 Association of Cullin1 haplotype variants with rheumatoid arthritis and response to methotrexate.Pharmacogenet Genomics. 2011 Sep;21(9):590-3. doi: 10.1097/FPC.0b013e3283492af7.
1179 Implication of CXCL5 (epithelial neutrophil-activating peptide 78) in the development of insulin resistance in patients with rheumatoid arthritis.Clin Exp Rheumatol. 2019 May-Jun;37(3):373-379. Epub 2018 Sep 17.
1180 Initiation of Disease-Modifying Therapies in Rheumatoid Arthritis Is Associated With Changes in Blood Pressure.J Clin Rheumatol. 2018 Jun;24(4):203-209. doi: 10.1097/RHU.0000000000000736.
1181 Hydroxytyrosol promotes autophagy by regulating SIRT1 against advanced oxidation protein productinduced NADPH oxidase and inflammatory response.Int J Mol Med. 2019 Oct;44(4):1531-1540. doi: 10.3892/ijmm.2019.4300. Epub 2019 Aug 5.
1182 Changes in apoptotic gene expression in lymphocytes from rheumatoid arthritis and systemic lupus erythematosus patients compared with healthy lymphocytes.J Clin Immunol. 2010 Sep;30(5):649-58. doi: 10.1007/s10875-010-9429-y. Epub 2010 Jun 9.
1183 Extracellular traps and PAD4 released by macrophages induce citrullination and auto-antibody production in autoimmune arthritis.J Autoimmun. 2019 Dec;105:102297. doi: 10.1016/j.jaut.2019.06.008. Epub 2019 Jul 2.
1184 Genetic and expression analysis of SNPs in the human deoxyribonuclease II: SNPs in the promoter region reduce its in vivo activity through decreased promoter activity.Electrophoresis. 2012 Sep;33(18):2852-8. doi: 10.1002/elps.201200260.
1185 A noncanonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis.Nat Immunol. 2019 Feb;20(2):141-151. doi: 10.1038/s41590-018-0293-x. Epub 2019 Jan 14.
1186 Collagen-induced arthritis mediated by HLA-DR1 (*0101) and HLA-DR4 (*0401).Am J Med Sci. 2004 Apr;327(4):169-79. doi: 10.1097/00000441-200404000-00002.
1187 Hypermethylation of EBF3 and IRX1 genes in synovial fibroblasts of patients with rheumatoid arthritis.Mol Cells. 2013 Apr;35(4):298-304. doi: 10.1007/s10059-013-2302-0. Epub 2013 Feb 26.
1188 Fibulin-4 is a target of autoimmunity predominantly in patients with osteoarthritis.J Immunol. 2006 Mar 1;176(5):3196-204. doi: 10.4049/jimmunol.176.5.3196.
1189 EF-hand domain containing 2 (Efhc2) is crucial for distal segmentation of pronephros in zebrafish.Cell Biosci. 2018 Oct 16;8:53. doi: 10.1186/s13578-018-0253-z. eCollection 2018.
1190 ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation.J Biol Chem. 2004 Mar 26;279(13):12794-803. doi: 10.1074/jbc.M308593200. Epub 2004 Jan 8.
1191 ENHO gene expression and serum adropin level in rheumatoid arthritis and systemic lupus erythematosus.Adv Clin Exp Med. 2018 Dec;27(12):1637-1641. doi: 10.17219/acem/75944.
1192 Local production of complement proteins in rheumatoid arthritis synovium.Arthritis Rheum. 2002 Apr;46(4):934-45. doi: 10.1002/art.10183.
1193 Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases.PLoS One. 2019 Oct 9;14(10):e0223246. doi: 10.1371/journal.pone.0223246. eCollection 2019.
1194 Detection of TT virus in patients with idiopathic inflammatory myopathies.Ann N Y Acad Sci. 2005 Jun;1050:304-13. doi: 10.1196/annals.1313.032.
1195 Expression of TNF-alpha and related signaling molecules in the peripheral blood mononuclear cells of rheumatoid arthritis patients.Mediators Inflamm. 2006;2006(3):12682. doi: 10.1155/MI/2006/12682.
1196 Reduction of SR Ca(2+) leak and arrhythmogenic cellular correlates by SMP-114, a novel CaMKII inhibitor with oral bioavailability.Basic Res Cardiol. 2017 Jul;112(4):45. doi: 10.1007/s00395-017-0637-y. Epub 2017 Jun 13.
1197 Fibrosis-4 index at diagnosis can predict all-cause mortality in patients with rheumatoid arthritis: A retrospective monocentric study.Mod Rheumatol. 2020 Jan;30(1):70-77. doi: 10.1080/14397595.2018.1558760. Epub 2019 Jan 15.
1198 Highly Expression of CD11b and CD32 on Peripheral Blood Mononuclear Cells from Patients with Adult-Onset Still's Disease.Int J Mol Sci. 2017 Jan 19;18(1):202. doi: 10.3390/ijms18010202.
1199 Brief Report: Anti-Carbamylated Protein Antibodies in Rheumatoid Arthritis Patients Are Reactive With Specific Epitopes of the Human Fibrinogen -Chain.Arthritis Rheumatol. 2017 Jul;69(7):1381-1386. doi: 10.1002/art.40098. Epub 2017 Jun 5.
1200 A mutation in a CD44 variant of inflammatory cells enhances the mitogenic interaction of FGF with its receptor.J Clin Invest. 2003 Apr;111(8):1211-20. doi: 10.1172/JCI17100.
1201 FHL2 regulates the resolution of tissue damage in chronic inflammatory arthritis.Ann Rheum Dis. 2015 Dec;74(12):2216-23. doi: 10.1136/annrheumdis-2013-205061. Epub 2014 Aug 14.
1202 Incidence of rheumatoid arthritis, psoriatic arthritis and polymyalgia rheumatica in an inland area of central Italy: results of the CAMPO-RHE study.Postgrad Med. 2018 Jan;130(1):137-141. doi: 10.1080/00325481.2018.1399774. Epub 2017 Nov 3.
1203 Analysis of TAP and HLA-DM polymorphism in thai rheumatoid arthritis.Hum Immunol. 2000 Mar;61(3):309-13. doi: 10.1016/s0198-8859(99)00163-9.
1204 Fms-like tyrosine kinase 3 ligand controls formation of regulatory T cells in autoimmune arthritis.PLoS One. 2013;8(1):e54884. doi: 10.1371/journal.pone.0054884. Epub 2013 Jan 21.
1205 Association of FOXJ1 polymorphisms with systemic lupus erythematosus and rheumatoid arthritis in Korean population.Exp Mol Med. 2007 Dec 31;39(6):805-11. doi: 10.1038/emm.2007.87.
1206 Rosmarinic acid reduces the resistance of gastric carcinoma cells to 5-fluorouracil by downregulating FOXO4-targeting miR-6785-5p.Biomed Pharmacother. 2019 Jan;109:2327-2334. doi: 10.1016/j.biopha.2018.10.061. Epub 2018 Nov 30.
1207 Discovery and analysis of inflammatory disease-related genes using cDNA microarrays.Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2150-5. doi: 10.1073/pnas.94.6.2150.
1208 Gene expression profile predicting the response to anti-TNF treatment in patients with rheumatoid arthritis; analysis of GEO datasets.Joint Bone Spine. 2014 Jul;81(4):325-30. doi: 10.1016/j.jbspin.2014.01.013. Epub 2014 Feb 20.
1209 CR6-interacting factor 1 controls autoimmune arthritis by regulation of signal transducer and activator of transcription 3 pathway and T helper type 17 cells.Immunology. 2019 Apr;156(4):413-421. doi: 10.1111/imm.13042. Epub 2019 Jan 28.
1210 MicroRNAs in rheumatoid arthritis: From pathogenesis to clinical impact.Autoimmun Rev. 2019 Nov;18(11):102391. doi: 10.1016/j.autrev.2019.102391. Epub 2019 Sep 11.
1211 GDF11 antagonizes TNF--induced inflammation and protects against the development of inflammatory arthritis in mice.FASEB J. 2019 Mar;33(3):3317-3329. doi: 10.1096/fj.201801375RR. Epub 2018 Nov 8.
1212 A longitudinal genome-wide association study of anti-tumor necrosis factor response among Japanese patients with rheumatoid arthritis.Arthritis Res Ther. 2016 Jan 18;18:12. doi: 10.1186/s13075-016-0920-6.
1213 RNA sequencing to predict response to TNF- inhibitors reveals possible mechanism for nonresponse in smokers.Expert Rev Clin Immunol. 2018 Jul;14(7):623-633. doi: 10.1080/1744666X.2018.1480937. Epub 2018 Jun 6.
1214 Measurement of absolute copy number variation of Glutathione S-Transferase M1 gene by digital droplet PCR and association analysis in Tunisian Rheumatoid Arthritis population.J Clin Lab Anal. 2018 Mar;32(3):e22300. doi: 10.1002/jcla.22300. Epub 2017 Jul 13.
1215 Association of GTF2IRD1-GTF2I polymorphisms with neuromyelitis optica spectrum disorders in Han Chinese patients.Neural Regen Res. 2019 Feb;14(2):346-353. doi: 10.4103/1673-5374.244800.
1216 Granzyme A Contributes to Inflammatory Arthritis in Mice Through Stimulation of Osteoclastogenesis.Arthritis Rheumatol. 2017 Feb;69(2):320-334. doi: 10.1002/art.39857.
1217 Increased intra-articular granzyme M may trigger local IFN-1/IL-29 response in rheumatoid arthritis.Clin Exp Rheumatol. 2020 Mar-Apr;38(2):220-226. doi: 10.55563/clinexprheumatol/ffb107. Epub 2019 Jun 6.
1218 Histone Protein Epitope Mapping for Autoantibody Recognition in Rheumatoid Arthritis.Methods Mol Biol. 2019;1901:221-228. doi: 10.1007/978-1-4939-8949-2_18.
1219 The potential role of human endogenous retrovirus K10 in the pathogenesis of rheumatoid arthritis: a preliminary study.Ann Rheum Dis. 2006 May;65(5):612-6. doi: 10.1136/ard.2004.031146. Epub 2005 Sep 28.
1220 Expression analysis of three isoforms of hyaluronan synthase and hyaluronidase in the synovium of knees in osteoarthritis and rheumatoid arthritis by quantitative real-time reverse transcriptase polymerase chain reaction.Arthritis Res Ther. 2004;6(6):R514-20. doi: 10.1186/ar1223. Epub 2004 Sep 22.
1221 Manifestation of rheumatoid arthritis in a patient with hereditary haemochromatosis.Rheumatol Int. 2006 Aug;26(10):939-41. doi: 10.1007/s00296-006-0113-8. Epub 2006 Feb 9.
1222 Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis.Am J Hum Genet. 2016 Aug 4;99(2):366-74. doi: 10.1016/j.ajhg.2016.06.019.
1223 An Immunochip-based interaction study of contrasting interaction effects with smoking in ACPA-positive versus ACPA-negative rheumatoid arthritis.Rheumatology (Oxford). 2016 Jan;55(1):149-55. doi: 10.1093/rheumatology/kev285. Epub 2015 Aug 13.
1224 Association of biomarkers of inflammation and HLA-DRB1 gene locus with risk of developing rheumatoid arthritis in females.Rheumatol Int. 2019 Dec;39(12):2147-2157. doi: 10.1007/s00296-019-04429-y. Epub 2019 Aug 26.
1225 Polymorphisms within the human leucocyte antigen-E gene and their associations with susceptibility to rheumatoid arthritis as well as clinical outcome of anti-tumour necrosis factor therapy. Clin Exp Immunol. 2015 Dec;182(3):270-7.
1226 Identification of autoantibodies to the I protein of the heterogeneous nuclear ribonucleoprotein complex in patients with systemic sclerosis.Arthritis Rheum. 1996 Oct;39(10):1669-76. doi: 10.1002/art.1780391009.
1227 Expression of HOXB2, a retinoic acid signaling target in pancreatic cancer and pancreatic intraepithelial neoplasia.Clin Cancer Res. 2005 May 1;11(9):3587-96. doi: 10.1158/1078-0432.CCR-04-1813.
1228 Regulatory effects of paeoniflorin-6'-O-benzene sulfonate (CP-25) on dendritic cells maturation and activation via PGE2-EP4 signaling in adjuvant-induced arthritic rats.Inflammopharmacology. 2019 Oct;27(5):997-1010. doi: 10.1007/s10787-019-00575-8. Epub 2019 Feb 15.
1229 HOXD10 silencing suppresses human fibroblast-like synoviocyte migration in rheumatoid arthritis via downregulation of the p38/JNK pathway.Exp Ther Med. 2018 Sep;16(3):1621-1628. doi: 10.3892/etm.2018.6432. Epub 2018 Jul 9.
1230 Expression of HOXD9 in fibroblast-like synoviocytes from rheumatoid arthritis patients.Int J Mol Med. 2002 Jul;10(1):41-8.
1231 Expression and Functions of Immediate Early Response Gene X-1 (IEX-1) in Rheumatoid Arthritis Synovial Fibroblasts.PLoS One. 2016 Oct 13;11(10):e0164350. doi: 10.1371/journal.pone.0164350. eCollection 2016.
1232 IFI44L promoter methylation as a blood biomarker for systemic lupus erythematosus.Ann Rheum Dis. 2016 Nov;75(11):1998-2006. doi: 10.1136/annrheumdis-2015-208410. Epub 2016 Jan 19.
1233 NF-B1/IKK Gene Expression and Clinical Activity in Patients With Rheumatoid Arthritis.Lab Med. 2017 Dec 22;49(1):11-17. doi: 10.1093/labmed/lmx033.
1234 Genetic variant of IL-10RA and susceptibility to rheumatoid arthritis in a Chinese population.Clin Rheumatol. 2017 Apr;36(4):825-830. doi: 10.1007/s10067-016-3449-9. Epub 2016 Oct 29.
1235 IL-18BP is decreased in osteoporotic women: Prevents Inflammasome mediated IL-18 activation and reduces Th17 differentiation.Sci Rep. 2016 Sep 21;6:33680. doi: 10.1038/srep33680.
1236 IL-38: A New Player in Inflammatory Autoimmune Disorders.Biomolecules. 2019 Aug 5;9(8):345. doi: 10.3390/biom9080345.
1237 The IL-20 Cytokine Family in Rheumatoid Arthritis and Spondyloarthritis.Front Immunol. 2018 Sep 25;9:2226. doi: 10.3389/fimmu.2018.02226. eCollection 2018.
1238 IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors.Am J Hum Genet. 2019 May 2;104(5):879-895. doi: 10.1016/j.ajhg.2019.03.012. Epub 2019 Apr 18.
1239 Identification of IRX1 as a Risk Locus for Rheumatoid Factor Positivity in Rheumatoid Arthritis in a Genome-Wide Association Study.Arthritis Rheumatol. 2016 Jun;68(6):1384-91. doi: 10.1002/art.39591.
1240 Iroquois transcription factor irx2a is required for multiciliated and transporter cell fate decisions during zebrafish pronephros development.Sci Rep. 2019 Apr 23;9(1):6454. doi: 10.1038/s41598-019-42943-y.
1241 High Interleukin-37 (IL-37) Expression and Increased Mucin-Domain Containing-3 (TIM-3) on Peripheral T Cells in Patients with Rheumatoid Arthritis.Med Sci Monit. 2018 Aug 14;24:5660-5667. doi: 10.12659/MSM.909254.
1242 Persistence of a large population of exhausted monoclonal B cells in mixed cryoglobuliemia after the eradication of hepatitis C virus infection.J Clin Immunol. 2012 Aug;32(4):729-35. doi: 10.1007/s10875-012-9677-0. Epub 2012 Mar 2.
1243 Junctional adhesion molecule C mediates leukocyte adhesion to rheumatoid arthritis synovium.Arthritis Rheum. 2008 Oct;58(10):3020-9. doi: 10.1002/art.23867.
1244 Enhanced expression of tumor necrosis factor receptor mRNA and protein in mononuclear cells isolated from rheumatoid arthritis synovial joints.Eur J Immunol. 1992 Jul;22(7):1907-12. doi: 10.1002/eji.1830220734.
1245 Combining naproxen and a dual amylin and calcitonin receptor agonist improves pain and structural outcomes in the collagen-induced arthritis rat model.Arthritis Res Ther. 2019 Feb 22;21(1):68. doi: 10.1186/s13075-019-1819-9.
1246 Induction of Krppel-like factor 2 reduces K/BxN serum-induced arthritis.J Cell Mol Med. 2019 Feb;23(2):1386-1395. doi: 10.1111/jcmm.14041. Epub 2018 Dec 3.
1247 Inhibitory NKG2A and activating NKG2D and NKG2C natural killer cell receptor genes: susceptibility for rheumatoid arthritis.Tissue Antigens. 2008 Oct;72(4):342-6. doi: 10.1111/j.1399-0039.2008.01110.x. Epub 2008 Aug 12.
1248 Influence of CD94 and NKG2A variants on susceptibility to rheumatoid arthritis and efficacy of anti-TNF treatment.Joint Bone Spine. 2016 Jan;83(1):75-9. doi: 10.1016/j.jbspin.2015.06.010. Epub 2015 Oct 6.
1249 An SNP-guided microRNA map of fifteen common human disorders identifies a consensus disease phenocode aiming at principal components of the nuclear import pathway.Cell Cycle. 2008 Aug 15;7(16):2570-83. doi: 10.4161/cc.7.16.6524. Epub 2008 Aug 30.
1250 Association of Distinct Fine Specificities of Anti-Citrullinated Peptide Antibodies With Elevated Immune Responses to Prevotella intermedia in a Subgroup of Patients With Rheumatoid Arthritis and Periodontitis.Arthritis Rheumatol. 2017 Dec;69(12):2303-2313. doi: 10.1002/art.40227. Epub 2017 Oct 30.
1251 The soluble leukocyte-associated Ig-like receptor (LAIR)-2 antagonizes the collagen/LAIR-1 inhibitory immune interaction.J Immunol. 2008 Feb 1;180(3):1662-9. doi: 10.4049/jimmunol.180.3.1662.
1252 LBH Gene Transcription Regulation by the Interplay of an Enhancer Risk Allele and DNA Methylation in Rheumatoid Arthritis.Arthritis Rheumatol. 2016 Nov;68(11):2637-2645. doi: 10.1002/art.39746.
1253 Non-synonymous single nucleotide polymorphisms in genes for immunoregulatory galectins: association of galectin-8 (F19Y) occurrence with autoimmune diseases in a Caucasian population.Biochim Biophys Acta. 2012 Oct;1820(10):1512-8. doi: 10.1016/j.bbagen.2012.05.015. Epub 2012 Jun 7.
1254 Galectin-9 Is a Possible Promoter of Immunopathology in Rheumatoid Arthritis by Activation of Peptidyl Arginine Deiminase 4 (PAD-4) in Granulocytes.Int J Mol Sci. 2019 Aug 19;20(16):4046. doi: 10.3390/ijms20164046.
1255 Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis.J Exp Med. 2009 Jun 8;206(6):1435-49. doi: 10.1084/jem.20082251. Epub 2009 May 18.
1256 Evaluation of differentially expressed genes by a combination of cDNA array and RAP-PCR using the AtlasImage 2.0 software.J Autoimmun. 2003 Sep;21(2):161-6. doi: 10.1016/s0896-8411(03)00088-x.
1257 Gene-gene interaction and RNA splicing profiles of MAP2K4 gene in rheumatoid arthritis.Clin Immunol. 2015 May;158(1):19-28. doi: 10.1016/j.clim.2015.02.011. Epub 2015 Feb 27.
1258 MAST3 modulates the inflammatory response and proliferation of fibroblast-like synoviocytes in rheumatoid arthritis.Int Immunopharmacol. 2019 Dec;77:105900. doi: 10.1016/j.intimp.2019.105900. Epub 2019 Oct 20.
1259 Association study of MIA3 rs17465637 polymorphism with cardiovascular disease in rheumatoid arthritis patients.DNA Cell Biol. 2012 Aug;31(8):1412-7. doi: 10.1089/dna.2012.1672. Epub 2012 May 11.
1260 HLA haplotypes and susceptibility to rheumatoid arthritis. More than class II genes.Scand J Rheumatol. 2002;31(5):275-8. doi: 10.1080/030097402760375160.
1261 Regulation of CCR5 expression and MIP-1alpha production in CD4+ T cells from patients with rheumatoid arthritis.Clin Exp Immunol. 2003 May;132(2):371-8. doi: 10.1046/j.1365-2249.2003.02126.x.
1262 Platelets induce a proinflammatory phenotype in monocytes via the CD147 pathway in rheumatoid arthritis.Arthritis Res Ther. 2014 Nov 18;16(6):478. doi: 10.1186/s13075-014-0478-0.
1263 Evaluation of pain intensity in people with rheumatoid arthritis using the MOS intensity scale.Med Clin (Barc). 2019 Aug 2;153(3):106-111. doi: 10.1016/j.medcli.2018.04.017. Epub 2018 May 25.
1264 The possible role of heat shock protein-70 induction in collagen-induced arthritis in rats.Physiol Int. 2019 Jun 1;106(2):128-139. doi: 10.1556/2060.106.2019.17. Epub 2019 Jul 2.
1265 Bone marrow mesenchymal stem cells in rheumatoid arthritis, spondyloarthritis, and ankylosing spondylitis: problems rather than solutions?.Arthritis Res Ther. 2019 Nov 13;21(1):239. doi: 10.1186/s13075-019-2014-8.
1266 New trajectories in the treatment of interstitial lung disease: treat the disease or treat the underlying pattern?.Curr Opin Pulm Med. 2019 Sep;25(5):442-449. doi: 10.1097/MCP.0000000000000600.
1267 Myosin IXB gene region and gluten intolerance: linkage to coeliac disease and a putative dermatitis herpetiformis association.J Med Genet. 2008 Apr;45(4):222-7. doi: 10.1136/jmg.2007.053991. Epub 2007 Dec 12.
1268 Variants in TNFAIP3, STAT4, and C12orf30 loci associated with multiple autoimmune diseases are also associated with juvenile idiopathic arthritis.Arthritis Rheum. 2009 Jul;60(7):2124-30. doi: 10.1002/art.24618.
1269 Identification of Naf1/ABIN-1 among TNF-alpha-induced expressed genes in human synoviocytes using oligonucleotide microarrays.FEBS Lett. 2003 Sep 11;551(1-3):8-12. doi: 10.1016/s0014-5793(03)00823-8.
1270 A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity.Arthritis Res Ther. 2007;9(5):R98. doi: 10.1186/ar2299.
1271 Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies.Arthritis Rheum. 2006 Jun;54(6):1906-16. doi: 10.1002/art.21890.
1272 Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes.Arthritis Res Ther. 2005;7(4):R844-51. doi: 10.1186/ar1752. Epub 2005 Apr 28.
1273 RIPK1 inhibition attenuates experimental autoimmune arthritis via suppression of osteoclastogenesis.J Transl Med. 2019 Mar 15;17(1):84. doi: 10.1186/s12967-019-1809-3.
1274 -2,3-Sialyltransferase 1 and neuraminidase-3 from monocytes in patients with rheumatoid arthritis correlate with disease activity measures: A pilot study.J Chin Med Assoc. 2019 Mar;82(3):179-185. doi: 10.1097/JCMA.0000000000000027.
1275 Identification of transcription regulatory relationships in rheumatoid arthritis and osteoarthritis.Clin Rheumatol. 2013 May;32(5):609-15. doi: 10.1007/s10067-012-2143-9. Epub 2013 Jan 8.
1276 NLRP6 facilitates the interaction between TAB2/3 and TRIM38 in rheumatoid arthritis fibroblast-like synoviocytes.FEBS Lett. 2017 Apr;591(8):1141-1149. doi: 10.1002/1873-3468.12622. Epub 2017 Mar 30.
1277 N-myristoyltransferase deficiency impairs activation of kinase AMPK and promotes synovial tissue inflammation.Nat Immunol. 2019 Mar;20(3):313-325. doi: 10.1038/s41590-018-0296-7. Epub 2019 Feb 4.
1278 Development of PEGylated carboxylic acid-modified polyamidoamine dendrimers as bone-targeting carriers for the treatment of bone diseases.J Control Release. 2017 Sep 28;262:10-17. doi: 10.1016/j.jconrel.2017.07.018. Epub 2017 Jul 11.
1279 TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.N Engl J Med. 2007 Sep 20;357(12):1199-209. doi: 10.1056/NEJMoa073491. Epub 2007 Sep 5.
1280 Whole exome sequencing in Finnish families identifies new candidate genes for osteoarthritis.PLoS One. 2018 Aug 29;13(8):e0203313. doi: 10.1371/journal.pone.0203313. eCollection 2018.
1281 Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation.Arthritis Rheum. 2007 Nov;56(11):3541-53. doi: 10.1002/art.22983.
1282 Atypical protein kinase C iota expression and aurothiomalate sensitivity in human lung cancer cells.Cancer Res. 2008 Jul 15;68(14):5888-95. doi: 10.1158/0008-5472.CAN-08-0438.
1283 Association of Autoimmune Regulator Gene Rs2075876 Variant, but Not Gene Expression with Alopecia Areata in Males: A Case-control Study.Immunol Invest. 2020 Feb;49(1-2):146-165. doi: 10.1080/08820139.2019.1671450. Epub 2019 Oct 11.
1284 Plasma and synovial fluid programmed cell death 5 (PDCD5) levels are inversely associated with TNF- and disease activity in patients with rheumatoid arthritis.Biomarkers. 2013 Mar;18(2):155-9. doi: 10.3109/1354750X.2012.759277. Epub 2013 Jan 18.
1285 Podoplanin in Inflammation and Cancer.Int J Mol Sci. 2019 Feb 6;20(3):707. doi: 10.3390/ijms20030707.
1286 PER2 is downregulated by the LPS-induced inflammatory response in synoviocytes in rheumatoid arthritis and is implicated in disease susceptibility.Mol Med Rep. 2017 Jul;16(1):422-428. doi: 10.3892/mmr.2017.6578. Epub 2017 May 11.
1287 Serum alarm antiproteases in systemic sclerosis patients.Hum Immunol. 2017 Sep;78(9):559-564. doi: 10.1016/j.humimm.2017.06.002. Epub 2017 Jun 9.
1288 Downregulated microRNA-135a ameliorates rheumatoid arthritis by inactivation of the phosphatidylinositol 3-kinase/AKT signaling pathway via phosphatidylinositol 3-kinase regulatory subunit 2.J Cell Physiol. 2019 Aug;234(10):17663-17676. doi: 10.1002/jcp.28390. Epub 2019 Mar 25.
1289 Metastable Atrial State Underlies the Primary Genetic Substrate for MYL4 Mutation-Associated Atrial Fibrillation.Circulation. 2020 Jan 28;141(4):301-312. doi: 10.1161/CIRCULATIONAHA.119.044268. Epub 2019 Nov 16.
1290 Expression and Regulation of PIWIL-Proteins and PIWI-Interacting RNAs in Rheumatoid Arthritis.PLoS One. 2016 Nov 28;11(11):e0166920. doi: 10.1371/journal.pone.0166920. eCollection 2016.
1291 Tumor-necrosis factor-alpha induces retinoic acid-inducible gene-I in rheumatoid fibroblast-like synoviocytes.Immunol Lett. 2009 Jan 29;122(1):89-93. doi: 10.1016/j.imlet.2008.12.005. Epub 2009 Jan 4.
1292 Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene.PLoS One. 2014 Feb 10;9(2):e87645. doi: 10.1371/journal.pone.0087645. eCollection 2014.
1293 PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing.Nat Immunol. 2018 Sep;19(9):942-953. doi: 10.1038/s41590-018-0179-y. Epub 2018 Aug 13.
1294 Molecular signature of retinoic acid treatment in acute promyelocytic leukemia.Oncogene. 2005 May 5;24(20):3358-68. doi: 10.1038/sj.onc.1208498.
1295 Polymorphisms in STAT4, PTPN2, PSORS1C1 and TRAF3IP2 Genes Are Associated with the Response to TNF Inhibitors in Patients with Rheumatoid Arthritis.PLoS One. 2017 Jan 20;12(1):e0169956. doi: 10.1371/journal.pone.0169956. eCollection 2017.
1296 Identification of novel mutations in CD2BP1 gene in clinically proven rheumatoid arthritis patients of south India.Eur J Med Genet. 2016 Aug;59(8):404-12. doi: 10.1016/j.ejmg.2016.05.009. Epub 2016 May 13.
1297 Anti-TNF treatment decreases the previously increased serum Indian Hedgehog levels in patients with ankylosing spondylitis and affects the expression of functional Hedgehog pathway target genes.Semin Arthritis Rheum. 2015 Jun;44(6):646-51. doi: 10.1016/j.semarthrit.2015.01.004. Epub 2015 Jan 23.
1298 TGF responsive tyrosine phosphatase promotes rheumatoid synovial fibroblast invasiveness.Ann Rheum Dis. 2016 Jan;75(1):295-302. doi: 10.1136/annrheumdis-2014-205790. Epub 2014 Nov 6.
1299 The prevalence and clinical significance of anti-PUF60 antibodies in patients with idiopathic inflammatory myopathy.Clin Rheumatol. 2018 Jun;37(6):1573-1580. doi: 10.1007/s10067-018-4031-4. Epub 2018 Mar 15.
1300 TNF-/calreticulin dual signaling induced NLRP3 inflammasome activation associated with HuR nucleocytoplasmic shuttling in rheumatoid arthritis.Inflamm Res. 2019 Jul;68(7):597-611. doi: 10.1007/s00011-019-01244-w. Epub 2019 May 22.
1301 Inflammasomes and human autoimmunity: A comprehensive review.J Autoimmun. 2015 Jul;61:1-8. doi: 10.1016/j.jaut.2015.05.001. Epub 2015 May 23.
1302 Tocilizumab modulates serum levels of adiponectin and chemerin in patients with rheumatoid arthritis: potential cardiovascular protective role of IL-6 inhibition.Clin Exp Rheumatol. 2019 Mar-Apr;37(2):293-300. Epub 2018 Aug 27.
1303 Expression and functional influence of cellular retinoic acid-binding protein II in renal cell carcinoma.Urol Int. 2005;75(3):269-76. doi: 10.1159/000087807.
1304 Changes in Radixin Expression and Interaction with Efflux Transporters in the Liver of Adjuvant-Induced Arthritic Rats.Inflammation. 2020 Feb;43(1):85-94. doi: 10.1007/s10753-019-01097-9.
1305 A novel gene-expression-signature-based model for prediction of response to Tripterysium glycosides tablet for rheumatoid arthritis patients.J Transl Med. 2018 Jul 4;16(1):187. doi: 10.1186/s12967-018-1549-9.
1306 Extracellular Vesicles Transfer the Receptor Programmed Death-1 in Rheumatoid Arthritis.Front Immunol. 2017 Jul 24;8:851. doi: 10.3389/fimmu.2017.00851. eCollection 2017.
1307 Generation of a robust model for inducing autoimmune arthritis in Sprague Dawley rats.J Pharmacol Toxicol Methods. 2020 Mar-Apr;102:106659. doi: 10.1016/j.vascn.2019.106659. Epub 2019 Dec 16.
1308 Local expression of the serum amyloid A and formyl peptide receptor-like 1 genes in synovial tissue is associated with matrix metalloproteinase production in patients with inflammatory arthritis.Arthritis Rheum. 2004 Jun;50(6):1788-99. doi: 10.1002/art.20301.
1309 SAMD9 is a (epi-) genetically regulated anti-inflammatory factor activated in RA patients.Mol Cell Biochem. 2019 Jun;456(1-2):135-144. doi: 10.1007/s11010-019-03499-7. Epub 2019 Feb 4.
1310 Constitutive upregulation of the transforming growth factor-beta pathway in rheumatoid arthritis synovial fibroblasts.Arthritis Res Ther. 2007;9(3):R59. doi: 10.1186/ar2217.
1311 Synthesis and activity of substituted 4-(indazol-3-yl)phenols as pathway-selective estrogen receptor ligands useful in the treatment of rheumatoid ... J Med Chem. 2004 Dec 16;47(26):6435-8.
1312 Analysis of critical molecules and signaling pathways in osteoarthritis and rheumatoid arthritis.Mol Med Rep. 2013 Feb;7(2):603-7. doi: 10.3892/mmr.2012.1224. Epub 2012 Dec 4.
1313 Increased miR-223 expression in T cells from patients with rheumatoid arthritis leads to decreased insulin-like growth factor-1-mediated interleukin-10 production.Clin Exp Immunol. 2014 Sep;177(3):641-51. doi: 10.1111/cei.12374.
1314 Expression of the precursor of secretoneurin, secretogranin II, in the synovium of patients with rheumatoid arthritis and osteoarthritis.J Rheumatol. 2000 Oct;27(10):2347-50.
1315 Syndecan-4 involves in the pathogenesis of rheumatoid arthritis by regulating the inflammatory response and apoptosis of fibroblast-like synoviocytes.J Cell Physiol. 2020 Feb;235(2):1746-1758. doi: 10.1002/jcp.29093. Epub 2019 Jul 15.
1316 Increased prevalence of semaphorin 3C, a repellent of sympathetic nerve fibers, in the synovial tissue of patients with rheumatoid arthritis.Arthritis Rheum. 2004 Apr;50(4):1156-63. doi: 10.1002/art.20110.
1317 Expression of Semaphorin 4A and its potential role in rheumatoid arthritis.Arthritis Res Ther. 2015 Aug 25;17(1):227. doi: 10.1186/s13075-015-0734-y.
1318 Ellagic acid attenuates testicular disruption in rheumatoid arthritis via targeting inflammatory signals, oxidative perturbations and apoptosis.Life Sci. 2019 Dec 15;239:117012. doi: 10.1016/j.lfs.2019.117012. Epub 2019 Oct 31.
1319 Dysregulation of interleukin-10-dependent gene expression in rheumatoid arthritis synovial macrophages.Arthritis Rheum. 2006 Sep;54(9):2711-21. doi: 10.1002/art.22055.
1320 The RA-MAP Consortium: a working model for academia-industry collaboration.Nat Rev Rheumatol. 2018 Jan;14(1):53-60. doi: 10.1038/nrrheum.2017.200. Epub 2017 Dec 7.
1321 The functional PTPN22 C1858T polymorphism confers risk for rheumatoid arthritis in patients from Central Mexico.Clin Rheumatol. 2016 Jun;35(6):1457-62. doi: 10.1007/s10067-016-3223-z. Epub 2016 Mar 7.
1322 Calreticulin induced endothelial ICAM-1 up-regulation associated with tristetraprolin expression alteration through PI3K/Akt/eNOS/p38 MAPK signaling pathway in rheumatoid arthritis.Mol Immunol. 2019 Mar;107:10-20. doi: 10.1016/j.molimm.2019.01.005. Epub 2019 Jan 9.
1323 Gene transfer of a cell cycle modulator exerts anti-inflammatory effects in the treatment of arthritis.J Immunol. 2003 Nov 1;171(9):4913-9. doi: 10.4049/jimmunol.171.9.4913.
1324 Proinflammatory Differentiation of Macrophages Through Microparticles That Form Immune Complexes Leads to T- and B-Cell Activation in Systemic Autoimmune Diseases.Front Immunol. 2019 Aug 28;10:2058. doi: 10.3389/fimmu.2019.02058. eCollection 2019.
1325 Systemic treatment with resveratrol alleviates adjuvant arthritis-interstitial lung disease in rats via modulation of JAK/STAT/RANKL signaling pathway.Pulm Pharmacol Ther. 2019 Jun;56:69-74. doi: 10.1016/j.pupt.2019.03.011. Epub 2019 Mar 28.
1326 The analysis of CIS, SOCS1, SOSC2 and SOCS3 transcript levels in peripheral blood mononuclear cells of systemic lupus erythematosus and rheumatoid arthritis patients.Clin Exp Med. 2008 Dec;8(4):179-85. doi: 10.1007/s10238-008-0006-0. Epub 2008 Sep 27.
1327 Genetic polymorphisms modifying oxidative stress are associated with disease activity in rheumatoid arthritis patients.Dis Markers. 2009;26(1):41-8. doi: 10.3233/DMA-2009-0603.
1328 Dyrk1A promotes the proliferation, migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis via down-regulating Spry2 and activating the ERK MAPK pathway.Tissue Cell. 2018 Dec;55:63-70. doi: 10.1016/j.tice.2018.10.002. Epub 2018 Oct 28.
1329 Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis.Ann Rheum Dis. 2018 Jul;77(7):1063-1069. doi: 10.1136/annrheumdis-2017-212614. Epub 2018 Mar 7.
1330 Peficitinib Inhibits the Chemotactic Activity of Monocytes via Proinflammatory Cytokine Production in Rheumatoid Arthritis Fibroblast-Like Synoviocytes.Cells. 2019 Jun 9;8(6):561. doi: 10.3390/cells8060561.
1331 Clinical and functional significance of STEAP4-splice variant in CD14(+) monocytes in patients with rheumatoid arthritis.Clin Exp Immunol. 2018 Mar;191(3):338-348. doi: 10.1111/cei.13076. Epub 2017 Nov 16.
1332 Flexible two-layer dissolving and safing microneedle transdermal of neurotoxin: A biocomfortable attempt to treat Rheumatoid Arthritis.Int J Pharm. 2019 May 30;563:91-100. doi: 10.1016/j.ijpharm.2019.03.033. Epub 2019 Mar 16.
1333 Serum substance P: an indicator of disease activity and subclinical inflammation in rheumatoid arthritis.Clin Rheumatol. 2018 Apr;37(4):901-908. doi: 10.1007/s10067-017-3929-6. Epub 2017 Dec 18.
1334 T cell activation Rho GTPase activating protein (TAGAP) is upregulated in clinical and experimental arthritis.Cytokine. 2018 Apr;104:130-135. doi: 10.1016/j.cyto.2017.10.002. Epub 2017 Oct 7.
1335 A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice.Exp Mol Med. 2019 Apr 26;51(4):1-19. doi: 10.1038/s12276-019-0244-0.
1336 Multidrug resistance 1 (MDR1) 3435C>T gene polymorphism influences the clinical phenotype and methotrexate-induced adverse events in South Indian Tamil rheumatoid arthritis. Eur J Clin Pharmacol. 2015 Aug;71(8):959-65.
1337 The oncoprotein TBX3 is controlling severity in experimental arthritis.Arthritis Res Ther. 2019 Jan 10;21(1):16. doi: 10.1186/s13075-018-1797-3.
1338 Down-regulation of miR-10a-5p promotes proliferation and restricts apoptosis via targeting T-box transcription factor 5 in inflamed synoviocytes.Biosci Rep. 2018 Apr 13;38(2):BSR20180003. doi: 10.1042/BSR20180003. Print 2018 Apr 27.
1339 Suicidal Behavior Among Hospitalized Adults With Inflammatory Bowel Disease: A United States Nationwide Analysis.Inflamm Bowel Dis. 2017 Dec 19;24(1):25-34. doi: 10.1093/ibd/izx005.
1340 Associations between single-nucleotide polymorphisms of RFC-1, GGH, MTHFR , TYMS, and TCII genes and the efficacy and toxicity of methotrexate treatment in patients with rheumatoid arthritis.Pol Arch Med Wewn. 2015;125(3):152-61. doi: 10.20452/pamw.2707. Epub 2015 Jan 19.
1341 LncRNA DILC participates in rheumatoid arthritis by inducing apoptosis of fibroblast-like synoviocytes and down-regulating IL-6.Biosci Rep. 2019 May 2;39(5):BSR20182374. doi: 10.1042/BSR20182374. Print 2019 May 31.
1342 MMP-8 and TIMP-1 are associated to periodontal inflammation in patients with rheumatoid arthritis under methotrexate immunosuppression - First results of a cross-sectional study.J Microbiol Immunol Infect. 2019 Jun;52(3):386-394. doi: 10.1016/j.jmii.2017.07.016. Epub 2017 Sep 4.
1343 Increased circulating myeloid-derived suppressor cells correlated negatively with Th17 cells in patients with rheumatoid arthritis.Scand J Rheumatol. 2013;42(2):85-90. doi: 10.3109/03009742.2012.716450. Epub 2012 Nov 6.
1344 Erratum to "Increased Expression of TLR10 in B Cell Subsets Correlates with Disease Activity in Rheumatoid Arthritis".Mediators Inflamm. 2019 Mar 10;2019:8419439. doi: 10.1155/2019/8419439. eCollection 2019.
1345 Role of Chondrocytes in the Development of Rheumatoid Arthritis Via Transmembrane Protein 147-Mediated NF-B Activation.Arthritis Rheumatol. 2020 Jun;72(6):931-942. doi: 10.1002/art.41182. Epub 2020 May 2.
1346 Topical all-trans retinoic acid (RA) induces an early, coordinated increase in RA-inducible skin-specific gene/psoriasin and cellular RA-binding protein II mRNA levels which precedes skin erythema.Arch Dermatol Res. 1996 Oct;288(11):664-9. doi: 10.1007/BF02505275.
1347 Dihydroartemisinin derivative DC32 attenuates collagen-induced arthritis in mice by restoring the Treg/Th17 balance and inhibiting synovitis through down-regulation of IL-6.Int Immunopharmacol. 2018 Dec;65:233-243. doi: 10.1016/j.intimp.2018.10.015. Epub 2018 Oct 15.
1348 Trex-1 deficiency in rheumatoid arthritis synovial fibroblasts.Arthritis Rheum. 2010 Sep;62(9):2673-9. doi: 10.1002/art.27567.
1349 Forkhead box o3a suppresses lipopolysaccharide-stimulated proliferation and inflammation in fibroblast-like synoviocytes through regulating tripartite motif-containing protein 3.J Cell Physiol. 2019 Nov;234(11):20139-20148. doi: 10.1002/jcp.28615. Epub 2019 Apr 13.
1350 GILZ: a new link between the hypothalamic pituitary adrenal axis and rheumatoid arthritis?.Immunol Cell Biol. 2014 Oct;92(9):747-51. doi: 10.1038/icb.2014.56. Epub 2014 Jul 22.
1351 MiR-338-5p suppresses rheumatoid arthritis synovial fibroblast proliferation and invasion by targeting ADAMTS-9.Clin Exp Rheumatol. 2018 Mar-Apr;36(2):195-202. Epub 2017 Aug 28.
1352 High levels of soluble GPR56/ADGRG1 are associated with positive rheumatoid factor and elevated tumor necrosis factor in patients with rheumatoid arthritis.J Microbiol Immunol Infect. 2018 Aug;51(4):485-491. doi: 10.1016/j.jmii.2016.11.010. Epub 2017 Jun 28.
1353 Association study of AFF1 rs340630 polymorphism with genetic susceptibility to rheumatoid arthritis in Chinese population.Braz J Med Biol Res. 2018;51(7):e7126. doi: 10.1590/1414-431x20187126. Epub 2018 May 17.
1354 Clues to pathogenesis of spondyloarthropathy derived from synovial fluid mononuclear cell gene expression profiles.J Rheumatol. 2002 Oct;29(10):2159-64.
1355 Fertility and Ovarian Reserve among Women with Rheumatoid Arthritis.J Rheumatol. 2019 May;46(5):455-459. doi: 10.3899/jrheum.180176. Epub 2018 Nov 15.
1356 Phosphoproteome analysis of synoviocytes from patients with rheumatoid arthritis.Int J Rheum Dis. 2017 Jun;20(6):708-721. doi: 10.1111/1756-185X.12997. Epub 2017 Mar 5.
1357 Contribution of Genetic Factors to Lower DHEAS in Patients with Rheumatoid Arthritis.Cell Mol Neurobiol. 2018 Jan;38(1):379-383. doi: 10.1007/s10571-017-0522-0. Epub 2017 Jul 15.
1358 The 4GalT1 affects the fibroblast-like synoviocytes invasion in rheumatoid arthritis by modifying N-linked glycosylation of CXCR3.Eur J Cell Biol. 2017 Mar;96(2):172-181. doi: 10.1016/j.ejcb.2017.02.001. Epub 2017 Feb 10.
1359 Bcl2 like protein-12 suppresses Foxp3(+) regulatory T cells in patients with rheumatoid arthritis.Am J Transl Res. 2019 May 15;11(5):3048-3055. eCollection 2019.
1360 Amelioration of adjuvant-induced arthritis in CCDC134-overexpressing transgenic mice.Biochem Biophys Res Commun. 2017 Aug 19;490(2):111-116. doi: 10.1016/j.bbrc.2017.05.166. Epub 2017 May 29.
1361 Associations between WNT1-inducible signaling pathway protein-1 (WISP-1) genetic polymorphisms and clinical aspects of rheumatoid arthritis among Chinese Han subjects.Medicine (Baltimore). 2019 Nov;98(44):e17604. doi: 10.1097/MD.0000000000017604.
1362 CD109 regulates the inflammatory response and is required for the pathogenesis of rheumatoid arthritis.Ann Rheum Dis. 2019 Dec;78(12):1632-1641. doi: 10.1136/annrheumdis-2019-215473. Epub 2019 Aug 27.
1363 Placement of selected new FDA-approved drugs in Medicare Part D formularies, 2009-2013.Am J Manag Care. 2018 Jun 1;24(6):e175-e182.
1364 Different Contributions of CDKAL1, KIF21B, and LRRK2/MUC19 Polymorphisms to SAPHO Syndrome, Rheumatoid Arthritis, Ankylosing Spondylitis, and Seronegative Spondyloarthropathy.Genet Test Mol Biomarkers. 2017 Feb;21(2):122-126. doi: 10.1089/gtmb.2016.0112. Epub 2016 Dec 12.
1365 Extracellular Chromatin Triggers Release of Soluble CEACAM8 Upon Activation of Neutrophils.Front Immunol. 2019 Jun 14;10:1346. doi: 10.3389/fimmu.2019.01346. eCollection 2019.
1366 Vitamin A and Retinoic Acid Exhibit Protective Effects on Necrotizing Enterocolitis by Regulating Intestinal Flora and Enhancing the IntestinalEpithelial Barrier.Arch Med Res. 2018 Jan;49(1):1-9. doi: 10.1016/j.arcmed.2018.04.003. Epub 2018 Apr 24.
1367 Deletion of calponin 2 in macrophages attenuates the severity of inflammatory arthritis in mice.Am J Physiol Cell Physiol. 2016 Oct 1;311(4):C673-C685. doi: 10.1152/ajpcell.00331.2015. Epub 2016 Aug 3.
1368 An overlap of Alport syndrome and rheumatoid arthritis in a patient and literature review.BMC Nephrol. 2019 Jul 23;20(1):277. doi: 10.1186/s12882-019-1462-3.
1369 Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis.Immunity. 2017 Jul 18;47(1):66-79.e5. doi: 10.1016/j.immuni.2017.06.018.
1370 A phase III study of BCD-055 compared with innovator infliximab in patients with active rheumatoid arthritis: 54-week results from the LIRA study.Rheumatol Int. 2019 Sep;39(9):1537-1546. doi: 10.1007/s00296-019-04359-9. Epub 2019 Jul 10.
1371 Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption.J Immunol. 2017 May 1;198(9):3436-3447. doi: 10.4049/jimmunol.1601716. Epub 2017 Mar 17.
1372 DPP-4 Inhibitor-Induced Rheumatoid Arthritis Among Diabetics: A Nested Case-Control Study.Diabetes Ther. 2018 Feb;9(1):141-151. doi: 10.1007/s13300-017-0353-5. Epub 2017 Dec 13.
1373 Hypomethylation of CYP2E1 and DUSP22 Promoters Associated With Disease Activity and Erosive Disease Among Rheumatoid Arthritis Patients.Arthritis Rheumatol. 2018 Apr;70(4):528-536. doi: 10.1002/art.40408. Epub 2018 Feb 18.
1374 Dishevelled2 promotes apoptosis and inhibits inflammatory cytokine secretion in rheumatoid arthritis fibroblast-like synoviocytes through crosstalk with the NF-B pathway.Oncotarget. 2017 Feb 21;8(8):12649-12663. doi: 10.18632/oncotarget.15172.
1375 STA-21, a STAT-3 inhibitor, attenuates the development and progression of inflammation in collagen antibody-induced arthritis.Immunobiology. 2017 Feb;222(2):206-217. doi: 10.1016/j.imbio.2016.10.001. Epub 2016 Oct 3.
1376 EOMES-positive CD4(+) Tcells are increased in PTPN22 (1858T) risk allele carriers.Eur J Immunol. 2018 Apr;48(4):655-669. doi: 10.1002/eji.201747296. Epub 2018 Feb 28.
1377 Baricitinib for Previously Treated Moderate or Severe Rheumatoid Arthritis: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.Pharmacoeconomics. 2018 Jul;36(7):769-778. doi: 10.1007/s40273-018-0616-7.
1378 Genetic deletion of GIT2 prolongs functional recovery and suppresses chondrocyte differentiation in rats with rheumatoid arthritis.J Cell Biochem. 2018 Feb;119(2):1538-1547. doi: 10.1002/jcb.26313. Epub 2017 Sep 18.
1379 Glycogen Metabolism and Rheumatoid Arthritis: The Role of Glycogen Synthase 1 in Regulation of Synovial Inflammation via Blocking AMP-Activated Protein Kinase Activation.Front Immunol. 2018 Jul 27;9:1714. doi: 10.3389/fimmu.2018.01714. eCollection 2018.
1380 Proteomics analysis reveals differential pattern of widespread protein expression and novel role of histidine-rich glycoprotein and lipopolysaccharide-binding protein in rheumatoid arthritis.Int J Biol Macromol. 2018 Apr 1;109:704-710. doi: 10.1016/j.ijbiomac.2017.12.075. Epub 2017 Dec 13.
1381 Absence of Pharmacokinetic Interactions between the Bruton's Tyrosine Kinase Inhibitor Fenebrutinib and Methotrexate.J Pharmacol Exp Ther. 2019 Oct;371(1):202-207. doi: 10.1124/jpet.119.257089. Epub 2019 Aug 1.
1382 Type I Interferon Gene Response Is Increased in Early and Established Rheumatoid Arthritis and Correlates with Autoantibody Production.Front Immunol. 2017 Mar 20;8:285. doi: 10.3389/fimmu.2017.00285. eCollection 2017.
1383 Type-III interferons and rheumatoid arthritis: Correlation between interferon lambda 1 (interleukin 29) and antimutated citrullinated vimentin antibody levels.Autoimmunity. 2017 Mar;50(2):82-85. doi: 10.1080/08916934.2017.1289181. Epub 2017 Feb 14.
1384 The Impact of MicroRNA-223-3p on IL-17 Receptor D Expression in Synovial Cells.PLoS One. 2017 Jan 5;12(1):e0169702. doi: 10.1371/journal.pone.0169702. eCollection 2017.
1385 Characterization of novel anti-IL-26 neutralizing monoclonal antibodies for the treatment of inflammatory diseases including psoriasis.MAbs. 2019 Nov-Dec;11(8):1428-1442. doi: 10.1080/19420862.2019.1654305. Epub 2019 Aug 18.
1386 IRAK2 is associated with susceptibility to rheumatoid arthritis.Clin Rheumatol. 2018 Apr;37(4):927-933. doi: 10.1007/s10067-017-3906-0. Epub 2017 Nov 11.
1387 Identification of novel biomarker as citrullinated inter-alpha-trypsin inhibitor heavy chain 4, specifically increased in sera with experimental and rheumatoid arthritis.Arthritis Res Ther. 2018 Apr 10;20(1):66. doi: 10.1186/s13075-018-1562-7.
1388 Downregulation of lncRNA ITSN1-2 correlates with decreased disease risk and activity of rheumatoid arthritis (RA), and reduces RA fibroblast-like synoviocytes proliferation and inflammation via inhibiting NOD2/RIP2 signaling pathway.Am J Transl Res. 2019 Aug 15;11(8):4650-4666. eCollection 2019.
1389 Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling.J Neurosci. 2017 Mar 8;37(10):2565-2579. doi: 10.1523/JNEUROSCI.2121-16.2017. Epub 2017 Feb 2.
1390 New genes associated with rheumatoid arthritis identified by gene expression profiling.Int J Immunogenet. 2017 Jun;44(3):107-113. doi: 10.1111/iji.12313. Epub 2017 Apr 2.
1391 Enhanced neutrophil autophagy and increased concentrations of IL-6, IL-8, IL-10 and MCP-1 in rheumatoid arthritis.Int Immunopharmacol. 2018 Dec;65:119-128. doi: 10.1016/j.intimp.2018.09.011. Epub 2018 Oct 9.
1392 Association of MTMR3 rs12537 at miR-181a binding site with rheumatoid arthritis and systemic lupus erythematosus risk in Egyptian patients.Sci Rep. 2019 Aug 23;9(1):12299. doi: 10.1038/s41598-019-48770-5.
1393 Expression of host defense scavenger receptors in spondylarthropathy.Arthritis Rheum. 2001 Apr;44(4):931-9. doi: 10.1002/1529-0131(200104)44:4<931::AID-ANR150>3.0.CO;2-T.
1394 Retinoic acid enhances germ cell differentiation of mouse skin-derived stem cells.J Ovarian Res. 2018 Mar 1;11(1):19. doi: 10.1186/s13048-018-0390-3.
1395 CCR5 silencing reduces inflammatory response, inhibits viability, and promotes apoptosis of synovial cells in rat models of rheumatoid arthritis through the MAPK signaling pathway.J Cell Physiol. 2019 Aug;234(10):18748-18762. doi: 10.1002/jcp.28514. Epub 2019 May 7.
1396 Mannan-Binding Lectin-Associated Serine Protease 1/3 Cleavage of Pro-Factor D into Factor D In Vivo and Attenuation of Collagen Antibody-Induced Arthritis through Their Targeted Inhibition by RNA Interference-Mediated Gene Silencing.J Immunol. 2016 Nov 1;197(9):3680-3694. doi: 10.4049/jimmunol.1600719. Epub 2016 Oct 5.
1397 Two new inflammatory markers associated with disease activity score-28 in patients with rheumatoid arthritis: Albumin to fibrinogen ratio and C-reactive protein to albumin ratio.Int Immunopharmacol. 2018 Sep;62:293-298. doi: 10.1016/j.intimp.2018.07.007. Epub 2018 Jul 23.
1398 METTL3 Attenuates LPS-Induced Inflammatory Response in Macrophages via NF-B Signaling Pathway.Mediators Inflamm. 2019 Oct 24;2019:3120391. doi: 10.1155/2019/3120391. eCollection 2019.
1399 Conserved 33-kb haplotype in the MHC class III region regulates chronic arthritis.Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):E3716-24. doi: 10.1073/pnas.1600567113. Epub 2016 Jun 14.
1400 Nesfatin-1 and visfatin expression is associated with reduced atherosclerotic disease risk in patients with rheumatoid arthritis.Peptides. 2018 Apr;102:31-37. doi: 10.1016/j.peptides.2018.02.002. Epub 2018 Feb 21.
1401 TNF- induces expression of the circadian clock gene Bmal1 via dual calcium-dependent pathways in rheumatoid synovial cells.Biochem Biophys Res Commun. 2018 Jan 8;495(2):1675-1680. doi: 10.1016/j.bbrc.2017.12.015. Epub 2017 Dec 5.
1402 Prolonged immunomodulation in inflammatory arthritis using the selective Kv1.3 channel blocker HsTX1[R14A] and its PEGylated analog.Clin Immunol. 2017 Jul;180:45-57. doi: 10.1016/j.clim.2017.03.014. Epub 2017 Apr 4.
1403 Rheumatoid arthritis-associated DNA methylation sites in peripheral blood mononuclear cells.Ann Rheum Dis. 2019 Jan;78(1):36-42. doi: 10.1136/annrheumdis-2018-213970. Epub 2018 Oct 8.
1404 lncRNA NTT/PBOV1 Axis Promotes Monocyte Differentiation and Is Elevated in Rheumatoid Arthritis.Int J Mol Sci. 2018 Sep 18;19(9):2806. doi: 10.3390/ijms19092806.
1405 Integrative analysis for identification of shared markers from various functional cells/tissues for rheumatoid arthritis.Immunogenetics. 2017 Feb;69(2):77-86. doi: 10.1007/s00251-016-0956-4. Epub 2016 Nov 3.
1406 Hypericin-photodynamic therapy inhibits proliferation and induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes cell line MH7A.Iran J Basic Med Sci. 2018 Feb;21(2):130-137. doi: 10.22038/IJBMS.2018.23871.5991.
1407 A Comprehensive Gene Expression Meta-analysis Identifies Novel Immune Signatures in Rheumatoid Arthritis Patients.Front Immunol. 2017 Feb 2;8:74. doi: 10.3389/fimmu.2017.00074. eCollection 2017.
1408 Expression of chemokines CXCL4 and CXCL7 by synovial macrophages defines an early stage of rheumatoid arthritis.Ann Rheum Dis. 2016 Apr;75(4):763-71. doi: 10.1136/annrheumdis-2014-206921. Epub 2015 Apr 9.
1409 Disease-Drug Interaction of Sarilumab and Simvastatin in Patients with Rheumatoid Arthritis.Clin Pharmacokinet. 2017 Jun;56(6):607-615. doi: 10.1007/s40262-016-0462-8.
1410 Resolution of TLR2-induced inflammation through manipulation of metabolic pathways in Rheumatoid Arthritis.Sci Rep. 2017 Feb 22;7:43165. doi: 10.1038/srep43165.
1411 Oligomeric S100A4 Is Associated With Monocyte Innate Immune Memory and Bypass of Tolerance to Subsequent Stimulation With Lipopolysaccharides.Front Immunol. 2019 Apr 15;10:791. doi: 10.3389/fimmu.2019.00791. eCollection 2019.
1412 Retinoic acid signalling is a candidate regulator of the expression of pituitary-specific transcription factor Prop1 in the developing rodent pituitary.J Neuroendocrinol. 2018 Mar;30(3):e12570. doi: 10.1111/jne.12570.
1413 Effects of once-monthly minodronate versus risedronate in osteoporosis patients with rheumatoid arthritis: a 12-month randomized head-to-head comparison.Osteoporos Int. 2018 Jul;29(7):1637-1642. doi: 10.1007/s00198-018-4494-9. Epub 2018 Mar 24.
1414 Regulator of Calcineurin 3 Ameliorates Autoimmune Arthritis by Suppressing Th17 Cell Differentiation.Am J Pathol. 2017 Sep;187(9):2034-2045. doi: 10.1016/j.ajpath.2017.05.008. Epub 2017 Jul 10.
1415 Maresin 1 improves the Treg/Th17 imbalance in rheumatoid arthritis through miR-21.Ann Rheum Dis. 2018 Nov;77(11):1644-1652. doi: 10.1136/annrheumdis-2018-213511. Epub 2018 Jul 25.
1416 Hypoxiainduced autophagy is inhibited by PADI4 knockdown, which promotes apoptosis of fibroblastlike synoviocytes in rheumatoid arthritis.Mol Med Rep. 2018 Apr;17(4):5116-5124. doi: 10.3892/mmr.2018.8501. Epub 2018 Jan 26.
1417 Siglec-9 is upregulated in rheumatoid arthritis and suppresses collagen-induced arthritis through reciprocal regulation of Th17-/Treg-cell differentiation.Scand J Immunol. 2017 Jun;85(6):433-440. doi: 10.1111/sji.12543.
1418 Dissecting the Role of NF-b Protein Family and Its Regulators in Rheumatoid Arthritis Using Weighted Gene Co-Expression Network.Front Genet. 2019 Nov 20;10:1163. doi: 10.3389/fgene.2019.01163. eCollection 2019.
1419 A pure polysaccharide from Ephedra sinica treating on arthritis and inhibiting cytokines expression.Int J Biol Macromol. 2016 May;86:177-88. doi: 10.1016/j.ijbiomac.2016.01.010. Epub 2016 Mar 17.
1420 Association of CD8(+) T-cells with bone erosion in patients with rheumatoid arthritis.Int J Rheum Dis. 2018 Feb;21(2):440-446. doi: 10.1111/1756-185X.13090. Epub 2017 May 16.
1421 Bone Remodeling and the Role of TRAF3 in Osteoclastic Bone Resorption.Front Immunol. 2018 Sep 28;9:2263. doi: 10.3389/fimmu.2018.02263. eCollection 2018.