Details of the Drug

General Information of Drug (ID: DMN8HRU)

Drug Name
Methoxyphenamine
Synonyms
Euspirol; METHOXYPHENAMINE; Methamphetamine, 2-methoxy; Methoxifenaminio; Methoxiphenadrin; Methoxiphenadrinum; Methoxyphenadrine; Methoxyphenamin; Methoxyphenamine [INN:BAN]; Methoxyphenaminum; Methoxyphenaminum [INN-Latin]; Metossifenamina [DCIT]; Metoxifenaminio [INN-Spanish]; Orthoxine; Ortodrinex; Ortoxine; Oxalacetic acid orthoxine; Proasma; 2-Methoxy-N,alpha-dimethylphenethylamin; 2-Methoxy-N-methylamphetamine; 2-Methoxymethamphetamine; 93-30-1; Asmi; EINECS 202-237-7; o-Methoxy-N,alpha-dimethylphenethylamine
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 179.26
Logarithm of the Partition Coefficient (xlogp) 2.6
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 2
Chemical Identifiers
Formula
C11H17NO
IUPAC Name
1-(2-methoxyphenyl)-N-methylpropan-2-amine
Canonical SMILES
CC(CC1=CC=CC=C1OC)NC
InChI
OEHAYUOVELTAPG-UHFFFAOYSA-N
InChIKey
1S/C11H17NO/c1-9(12-2)8-10-6-4-5-7-11(10)13-3/h4-7,9,12H,8H2,1-3H3
Cross-matching ID
PubChem CID
4117
ChEBI ID
CHEBI:134817
CAS Number
93-30-1
DrugBank ID
DB13624
INTEDE ID
DR1049

Molecular Interaction Atlas of This Drug


Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 2D6 (CYP2D6)
Main DME 		DECB0K3 CP2D6_HUMAN Substrate [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Metabolism of methoxyphenamine and 2-methoxyamphetamine in P4502D6-transfected cells and cell preparations. Xenobiotica. 1995 Sep;25(9):895-906.