Details of the Drug

General Information of Drug (ID: DMNUXKA)

Drug Name

INCAGN01876

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 2	[1]
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Drug Type

Antibody

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Activation-inducible TNFR family receptor (TNFRSF18)	TTG6LA7	TNR18_HUMAN	Agonist	[2]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Solid tumour/cancer

ICD Disease Classification

2A00-2F9Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Activation-inducible TNFR family receptor (TNFRSF18)	DTT	TNFRSF18	2.39E-03	-0.54	-0.7

Molecular Expression Atlas (MEA)

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References

1	ClinicalTrials.gov (NCT03277352) INCAGN01876 in Combination With Immune Therapies in Subjects With Advanced or Metastatic Malignancies. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Agenus.