Details of the Drug

General Information of Drug (ID: DMNZAVE)

• Drug Name: 1h-Benoximidazole-2-Carboxylic Acid
• Synonyms: 1H-Benzimidazole-2-carboxylic acid; 2849-93-6; 2-Benzimidazolecarboxylic acid; 1H-benzo[d]imidazole-2-carboxylic acid; Benzimidazole-2-carboxylic acid; 1H-Benzoimidazole-2-carboxylic acid; 1H-1,3-benzodiazole-2-carboxylic acid; Benzoimidazole-2-carboxylic acid; benzimidazole-2-yl-carboxylic acid; 1H-BENOXIMIDAZOLE-2-CARBOXYLIC ACID; 1h-1,3-benzimidazole-2-carboxylic acid; RHXSYTACTOMVLJ-UHFFFAOYSA-N; PubChem8062; AC1L5PLZ; benzimidazolecarboxylic acid; AC1Q1HJ4; benzimidazole carboxylic acid; 2-Carboxy-1H-benzimidazole

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 162.15
  Logarithm of the Partition Coefficient (xlogp); 1.1
  Rotatable Bond Count (rotbonds); 1
  Hydrogen Bond Donor Count (hbonddonor); 2
  Hydrogen Bond Acceptor Count (hbondacc); 3
• Chemical Identifiers:
  Formula: C8H6N2O2
  IUPAC Name: 1H-benzimidazole-2-carboxylic acid
  Canonical SMILES: C1=CC=C2C(=C1)NC(=N2)C(=O)O
  InChI: InChI=1S/C8H6N2O2/c11-8(12)7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H,9,10)(H,11,12)
  InChIKey: RHXSYTACTOMVLJ-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 233240
  ChEBI ID: CHEBI:46117
  CAS Number: 2849-93-6
  DrugBank ID: DB03028
  TTD ID: D0W5NB

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cathepsin D (CTSD)	TTPT2QI	CATD_HUMAN	Inhibitor	[1]

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.