Details of the Drug

General Information of Drug (ID: DMO1D9E)

Drug Name

VX-522

Indication

Disease Entry	ICD 11	Status	REF
Cystic fibrosis	CA25	Phase 1	[1]
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Drug Type

mRNA therapy

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
cAMP-dependent chloride channel (CFTR)	TTRLZHP	CFTR_HUMAN	Not Available	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT05668741) A Phase 1 Single Dose Escalation Study Evaluating the Safety and Tolerability of VX-522 in Subjects 18 Years of Age and Older With Cystic Fibrosis and a CFTR Genotype Not Responsive to CFTR Modulator Therapy. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Vertex