Details of the Drug

General Information of Drug (ID: DMO2JBC)

• Drug Name: Methamphetamine hydrochloride
• Synonyms: Methamphetamine HCL; Methamphetamine hydrochloride; Methamphetaminium chloride; Methylamphetamine hydrochloride; Methylisomyn; Norodin hydrochloride; Adipex; Chestox; Deofed; Des-O-E; Desepin; Desodex; Desoxo-5; Desoxyfed; Desoxyne; Destim; Dexoval; Dexstim; Dextim; Dosoxy; Doxyfed; Drinalfa; Efroxine; Eufodrinal; Gerovit; Hyphet; Isophen; Isophen (VAN); Obedrin-LA; Pervitin; Philopon; Soxysympamine; Syndrox; Tonedron; d-Methaphetamine hydrochloride; (+)-Methamphetamine hydrochloride; 51-57-0; S-(+)-Methamphetamine hydrochloride
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight; 185.69
  Logarithm of the Partition Coefficient; Not Available
  Rotatable Bond Count; 3
  Hydrogen Bond Donor Count; 2
  Hydrogen Bond Acceptor Count; 1
• Chemical Identifiers:
  Formula: C10H16ClN
  IUPAC Name: (2S)-N-methyl-1-phenylpropan-2-amine;hydrochloride
  Canonical SMILES: CC(CC1=CC=CC=C1)NC.Cl
  InChI: TWXDDNPPQUTEOV-FVGYRXGTSA-N
  InChIKey: 1S/C10H15N.ClH/c1-9(11-2)8-10-6-4-3-5-7-10;/h3-7,9,11H,8H2,1-2H3;1H/t9-;/m0./s1
• Cross-matching ID:
  PubChem CID: 66124
  ChEBI ID: CHEBI:35340
  CAS Number: 51-57-0
  INTEDE ID: DR1041

Molecular Interaction Atlas of This Drug

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Cytochrome P450 2D6 (CYP2D6) Main DME	DECB0K3	CP2D6_HUMAN	Substrate	[1]

References

• [1] Cytochrome P450 2D6.1 and cytochrome P450 2D6.10 differ in catalytic activity for multiple substrates. Pharmacogenetics. 2001 Aug;11(6):477-87.