Details of the Drug

General Information of Drug (ID: DMO3KU5)

• Drug Name: Diclosan
• Synonyms: SONECLOSAN; DICLOSAN; 3380-30-1; 5-chloro-2-(4-chlorophenoxy)phenol; 5-Chloro-2-(p-chlorophenoxy)phenol; UNII-814H7B74XK; hydroxydichlorodiphenyl ether; Phenol, 5-chloro-2-(p-chlorophenoxy)-; 814H7B74XK; Snoclosan; Soneclosan [INN]; DCN; Tinosan HP-100; Phenol, 5-chloro-2-(4-chlorophenoxy)-; AC1L2CUC; AC1Q3QSN; EC 429-290-0; SCHEMBL465591; CHEMBL1232142; CTK1C4131; DTXSID80187464; ZINC2027016; ACT08242; AKOS027382858; DB04393; 4,4'-dichloro-2-hydroxydiphenyl ether

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 255.09
  Logarithm of the Partition Coefficient (xlogp); 4.4
  Rotatable Bond Count (rotbonds); 2
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 2
• Chemical Identifiers:
  Formula: C12H8Cl2O2
  IUPAC Name: 5-chloro-2-(4-chlorophenoxy)phenol
  Canonical SMILES: C1=CC(=CC=C1OC2=C(C=C(C=C2)Cl)O)Cl
  InChI: InChI=1S/C12H8Cl2O2/c13-8-1-4-10(5-2-8)16-12-6-3-9(14)7-11(12)15/h1-7,15H
  InChIKey: BYNQFCJOHGOKSS-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 18807
  CAS Number: 3380-30-1
  DrugBank ID: DB04393
  TTD ID: D03PJO

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Fatty acid synthetase I (Bact inhA)	TTVTX4N	INHA_MYCTU	Inhibitor	[1]

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.