Details of the Drug

General Information of Drug (ID: DMOVE31)

Drug Name
PRT-064445
Synonyms Anticoagulant antidote (bleeding), Portola; Factor Xa inhibitor antidote (bleeding), Portola
Indication
Disease Entry ICD 11 Status REF
Bleeding disorder GA20-GA21 Investigative [1]
Cross-matching ID
TTD ID
D0SP5Q

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor Xa (F10) TTCIHJA FA10_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Bleeding disorder
ICD Disease Classification GA20-GA21
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Coagulation factor Xa (F10) DTT F10 4.84E-02 -0.28 -0.9
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Semuloparin for the prevention of venous thromboembolic events in cancer patients. Drugs Today (Barc). 2012 Jul;48(7):451-7.