Details of the Drug

General Information of Drug (ID: DMPEZHC)

• Drug Name: N-glycylglycinehydroxamic acid
• Synonyms: N-glycylglycinehydroxamic acid; CHEMBL462481; AKOS013308170

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 147.13
  Logarithm of the Partition Coefficient (xlogp); -1.4
  Rotatable Bond Count (rotbonds); 3
  Hydrogen Bond Donor Count (hbonddonor); 4
  Hydrogen Bond Acceptor Count (hbondacc); 4
• Chemical Identifiers:
  Formula: C4H9N3O3
  IUPAC Name: 2-amino-N-[2-(hydroxyamino)-2-oxoethyl]acetamide
  Canonical SMILES: C(C(=O)NCC(=O)NO)N
  InChI: InChI=1S/C4H9N3O3/c5-1-3(8)6-2-4(9)7-10/h10H,1-2,5H2,(H,6,8)(H,7,9)
  InChIKey: NXTDAODSZSXXAY-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 10057636
  TTD ID: D09YRL

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Urease (Bact ureC)	TTAS2UO	URE1_KLEAE	Inhibitor	[1]

References

• [1] Design, synthesis, and evaluation of novel organophosphorus inhibitors of bacterial ureases. J Med Chem. 2008 Sep 25;51(18):5736-44.