Details of the Drug

General Information of Drug (ID: DMPSNSC)

Drug Name
XTMAB-16
Indication
Disease Entry ICD 11 Status REF
Sarcoidosis 4B20.5 Phase 1/2 [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
DU7G5P

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tumor necrosis factor (TNF) TTF8CQI TNFA_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Sarcoidosis
ICD Disease Classification 4B20.5
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tumor necrosis factor (TNF) DTT TNF 8.51E-01 0.05 0.27
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT05890729) A Seamless, Phase 1b/2 Multiple Ascending Dose/Proof of Concept Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis With or Without Extrapulmonary Manifestations. U.S.National Institutes of Health.
2 Clinical pipeline report, company report or official report of Xentria