Details of the Drug

General Information of Drug (ID: DMQ1GH4)

Drug Name
AEF0117
Indication
Disease Entry ICD 11 Status REF
Marijuana use disorder 6C41 Phase 2 [1]
Drug Type
Small molecular drug
Cross-matching ID
PubChem CID
139433957
TTD ID
DN8VS3

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cannabinoid receptor 1 (CB1) TT6OEDT CNR1_HUMAN Antagonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Marijuana use disorder
ICD Disease Classification 6C41
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Cannabinoid receptor 1 (CB1) DTT CNR1 5.59E-02 -0.22 -0.45
Cannabinoid receptor 1 (CB1) DTT CNR1 7.68E-01 -0.06 -0.46
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03717272) Effect of AEF0117 on Subjective Effects of Cannabis in CUD Subjects. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Affimed Therapeutics.