Details of the Drug

General Information of Drug (ID: DMRD8B8)

Drug Name

NSI-189

Synonyms

NSI-189; 1270138-40-3; (4-benzylpiperazin-1-yl)(2-(isopentylamino)pyridin-3-yl)methanone; UNII-YVE9U408ZL; YVE9U408ZL; NSI 189; (4-benzylpiperazin-1-yl)-[2-(3-methylbutylamino)pyridin-3-yl]methanone; Methanone, (2-((3-methylbutyl)amino)-3-pyridinyl)(4-(phenylmethyl)-1-piperazinyl)-; Methanone, [2-[(3-methylbutyl)amino]-3-pyridinyl][4-(phenylmethyl)-1-piperazinyl]-; NSI189; SCHEMBL9999791; EX-A277; MolPort-028-747-097; NS189; BCP08748; AOB87795; ZINC98023167; AKOS025395148; CS-2029; SB17520; NCGC00371142-05; DA-46482; AK199356

Indication

Disease Entry	ICD 11	Status	REF
Major depressive disorder	6A70.3	Phase 2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C22H30N4O
Canonical SMILES: CC(C)CCNC1=C(C=CC=N1)C(=O)N2CCN(CC2)CC3=CC=CC=C3
InChI: 1S/C22H30N4O/c1-18(2)10-12-24-21-20(9-6-11-23-21)22(27)26-15-13-25(14-16-26)17-19-7-4-3-5-8-19/h3-9,11,18H,10,12-17H2,1-2H3,(H,23,24)
InChIKey: DYTOQURYRYYNOR-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 50922681
CAS Number: 1270138-40-3
TTD ID: D06VHG

References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)