Details of the Drug

General Information of Drug (ID: DMRECC2)

Drug Name

YH006

Indication

Disease Entry	ICD 11	Status	REF
Aggressive cancer	2A00-2F9Z	Investigative	[1]
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Drug Type

Bispecific antibody

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cytotoxic T-lymphocyte protein 4 (CTLA-4)	TTI2S1D	CTLA4_HUMAN	Not Available	[1]
OX40L receptor (CD134)	TTL31H0	TNR4_HUMAN	Not Available	[1]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Aggressive cancer

ICD Disease Classification

2A00-2F9Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
OX40L receptor (CD134)	DTT	TNFRSF4	2.17E-06	1.01	1.66
Cytotoxic T-lymphocyte protein 4 (CTLA-4)	DTT	CTLA4	2.73E-01	0.02	0.05

Molecular Expression Atlas (MEA)

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References

1	Clinical pipeline report, company report or official report of Biocytogen