Details of the Drug

General Information of Drug (ID: DMRKOS1)

Drug Name
Oxilofrine
Synonyms Oxilofrine hydrochloride; Carnigen (TN)
Indication
Disease Entry ICD 11 Status REF
Orthostatic hypotension BA21 Approved [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 181.23
Logarithm of the Partition Coefficient (xlogp) 0.6
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C10H15NO2
IUPAC Name
4-[(1R,2S)-1-hydroxy-2-(methylamino)propyl]phenol
Canonical SMILES
C[C@@H]([C@@H](C1=CC=C(C=C1)O)O)NC
InChI
InChI=1S/C10H15NO2/c1-7(11-2)10(13)8-3-5-9(12)6-4-8/h3-7,10-13H,1-2H3/t7-,10-/m0/s1
InChIKey
OXFGTKPPFSCSMA-XVKPBYJWSA-N
Cross-matching ID
PubChem CID
688009
ChEBI ID
CHEBI:134822
CAS Number
365-26-4
DrugBank ID
DB11610
TTD ID
D07QLG

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adrenergic receptor (ADR) TTVIREA NOUNIPROTAC Modulator [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015