General Information of Drug (ID: DMRKYD6)

Drug Name
2-acetyl-3-hydroxycyclohex-2-enone
Synonyms
CHEMBL73025; 37514-00-4; SCHEMBL5628771; CTK1B5605; DTXSID50472617; YKOOMGHHVDVJAY-UHFFFAOYSA-N; 2-Acetyl-3-hydroxy-cyclohex-2-enone; 2-Acetyl-3-hydroxy-2-cyclohexen-1-one; 2-Cyclohexen-1-one, 2-acetyl-3-hydroxy-
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 154.16
Logarithm of the Partition Coefficient (xlogp) 0.7
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C8H10O3
IUPAC Name
2-acetyl-3-hydroxycyclohex-2-en-1-one
Canonical SMILES
CC(=O)C1=C(CCCC1=O)O
InChI
InChI=1S/C8H10O3/c1-5(9)8-6(10)3-2-4-7(8)11/h10H,2-4H2,1H3
InChIKey
YKOOMGHHVDVJAY-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
11788412
CAS Number
37514-00-4
TTD ID
D0R0XE

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Hydroxyphenylpyruvate dioxygenase (HPD) TT8DSFC HPPD_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Enzyme inhibition potency enhancement by active site metal chelating and hydrogen bonding induced conformation-restricted cyclopropanecarbonyl deri... Bioorg Med Chem Lett. 2006 Dec 1;16(23):6024-7.