Details of the Drug

General Information of Drug (ID: DMRT3FK)

Drug Name
RO5461111
Indication
Disease Entry ICD 11 Status REF
Systemic lupus erythematosus 4A40.0 Preclinical [1]
Cross-matching ID
PubChem CID
59543651
TTD ID
DC9J1Y

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cathepsin S (CTSS) TTUMQVO CATS_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Cathepsin S inhibition suppresses systemic lupus erythematosus and lupus nephritis because cathepsin S is essential for MHC class II-mediated CD4 T cell and B cell priming. Ann Rheum Dis. 2015 Feb;74(2):452-63.