Details of the Drug

General Information of Drug (ID: DMSPBOW)

Drug Name

AIC100

Indication

Disease Entry	ICD 11	Status	REF
Thyroid cancer	2D10	Phase 1	[1]
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Drug Type

CAR T Cell Therapy

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Intercellular adhesion molecule ICAM-1 (ICAM1)	TTCT6F7	ICAM1_HUMAN	Not Available	[2]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Thyroid cancer

ICD Disease Classification

2D10

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Intercellular adhesion molecule ICAM-1 (ICAM1)	DTT	ICAM1	5.21E-01	0.38	0.32

Molecular Expression Atlas (MEA)

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References

1	ClinicalTrials.gov (NCT04420754) Study of AIC100 in Relapsed/Refractory Thyroid Cancer. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of AffyImmune Therapeutics.