Details of the Drug

General Information of Drug (ID: DMSRUKQ)

Drug Name
DPN-205-734
Synonyms 5-(4-Cyanophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
Indication
Disease Entry ICD 11 Status REF
Cardiac disease BA00-BE2Z Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 235.24
Logarithm of the Partition Coefficient (xlogp) 0.8
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C14H9N3O
IUPAC Name
5-(4-cyanophenyl)-6-methyl-2-oxo-1H-pyridine-3-carbonitrile
Canonical SMILES
CC1=C(C=C(C(=O)N1)C#N)C2=CC=C(C=C2)C#N
InChI
InChI=1S/C14H9N3O/c1-9-13(6-12(8-16)14(18)17-9)11-4-2-10(7-15)3-5-11/h2-6H,1H3,(H,17,18)
InChIKey
NMIRAZSAZYNODX-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
145915
CAS Number
88594-78-9
TTD ID
D09TDK

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Phosphodiesterase (PDE) TTUST1O NOUNIPROTAC Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Pharmacological actions of DPN 205-734, a novel cardiotonic agent. J Cardiovasc Pharmacol. 1988 Oct;12(4):451-60.