Details of the Drug

General Information of Drug (ID: DMUR6OV)

Drug Name

RG-7356

Synonyms

RO-5429083; AR-001 series, ARIUS; ARH460-16-2; ChARH460-16-2; H460-16-2; MuARH460-16-2; Anti-CD44 antibody (cancer), ARIUS; Anti-CD44 mAb (cancer), Roche; Chimeric ARH460-16-2-IgG1; Chimeric ARH460-16-2-IgG2; (ch)ARH460-16-2-IgG1; (ch)ARH460-16-2-IgG2

Indication

Disease Entry	ICD 11	Status	REF
Haematological malignancy	2B33.Y	Discontinued in Phase 1	[1]
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Drug Type

Antibody

Cross-matching ID

TTD ID: D0DC1I

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Hyaluronic acid receptor (LYVE1)	TTG8DNU	LYVE1_HUMAN	Not Available	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034685)
2	Preclinical evaluation of 89Zr-labeled anti-CD44 monoclonal antibody RG7356 in mice and cynomolgus monkeys: Prelude to Phase 1 clinical studies. MAbs. 2014 Mar-Apr;6(2):567-75.